{"id":880,"date":"2016-11-01T15:40:04","date_gmt":"2016-11-01T14:40:04","guid":{"rendered":"http:\/\/the-three-city-study-3c.com\/?page_id=13"},"modified":"2022-02-22T10:44:09","modified_gmt":"2022-02-22T09:44:09","slug":"publications","status":"publish","type":"page","link":"https:\/\/the-three-city-study-3c.com\/index.php\/publications\/","title":{"rendered":"Publications"},"content":{"rendered":"<p><div class=\"fusion-fullwidth fullwidth-box fusion-builder-row-1 fusion-flex-container fusion-parallax-none nonhundred-percent-fullwidth non-hundred-percent-height-scrolling lazyload\" style=\"background-color: rgba(255,255,255,0);background-position: center center;background-repeat: no-repeat;border-width: 0px 0px 0px 0px;border-color:#eae9e9;border-style:solid;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;\" data-bg=\"https:\/\/the-three-city-study-3c.com\/wp-content\/uploads\/2021\/05\/science-hero.jpg\" ><div class=\"fusion-builder-row fusion-row fusion-flex-align-items-flex-start\" style=\"max-width:1216.8px;margin-left: calc(-4% \/ 2 );margin-right: calc(-4% \/ 2 );\"><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-0 fusion_builder_column_1_1 1_1 fusion-flex-column\"><div class=\"fusion-column-wrapper fusion-flex-justify-content-flex-start fusion-content-layout-column\" style=\"background-position:left top;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;padding: 84px 0px 41px 0px;\"><div style=\"text-align:center;\"><span class=\" fusion-imageframe imageframe-none imageframe-1 hover-type-none\"><img width=\"181\" height=\"154\" title=\"3C_2-removebg-preview\" src=\"data:image\/svg+xml,%3Csvg%20xmlns%3D%27http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg%27%20width%3D%27181%27%20height%3D%27154%27%20viewBox%3D%270%200%20181%20154%27%3E%3Crect%20width%3D%27181%27%20height%3D%27154%27%20fill-opacity%3D%220%22%2F%3E%3C%2Fsvg%3E\" data-orig-src=\"https:\/\/the-three-city-study-3c.com\/wp-content\/uploads\/2021\/08\/3C_2-removebg-preview.png\" class=\"lazyload img-responsive wp-image-1021\"\/><\/span><\/div><style type=\"text\/css\">@media only screen and (max-width:1024px) {.fusion-title.fusion-title-1{margin-top:0px!important; margin-right:0px!important;margin-bottom:31px!important;margin-left:0px!important;}}@media only screen and (max-width:640px) {.fusion-title.fusion-title-1{margin-top:0px!important; margin-right:0px!important;margin-bottom:20px!important; margin-left:0px!important;}}<\/style><div class=\"fusion-title title fusion-title-1 fusion-sep-none fusion-title-text fusion-title-size-one\" style=\"margin-top:0px;margin-right:0px;margin-bottom:31px;margin-left:0px;\"><h1 class=\"title-heading-left fusion-responsive-typography-calculated\" style=\"margin:0;color:#ffbfbf;--fontSize:110;line-height:1.1;\"><div style=\"text-align: center;\"><span style=\"color: #ffffff; font-family: var(--h1_typography-font-family); font-size: var(--h1_typography-font-size); font-style: var(--h1_typography-font-style,normal); font-weight: var(--h1_typography-font-weight); letter-spacing: var(--h1_typography-letter-spacing); background-color: rgba(255, 255, 255, 0);\">Publications<\/span><\/div><\/h1><\/div><\/div><style type=\"text\/css\">.fusion-body .fusion-builder-column-0{width:100% !important;margin-top : 0px;margin-bottom : 0px;}.fusion-builder-column-0 > .fusion-column-wrapper {padding-top : 84px !important;padding-right : 0px !important;margin-right : 1.92%;padding-bottom : 41px !important;padding-left : 0px !important;margin-left : 1.92%;}@media only screen and (max-width:1024px) {.fusion-body .fusion-builder-column-0{width:100% !important;order : 0;}.fusion-builder-column-0 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}@media only screen and (max-width:640px) {.fusion-body .fusion-builder-column-0{width:100% !important;order : 0;}.fusion-builder-column-0 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}<\/style><\/div><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-1 fusion_builder_column_1_4 1_4 fusion-flex-column\"><div class=\"fusion-column-wrapper fusion-flex-justify-content-flex-start fusion-content-layout-column\" style=\"background-position:left top;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;padding: 0px 0px 60px 0px;\"><div style=\"text-align:right;\"><style type=\"text\/css\">.fusion-button.button-1 .fusion-button-text, .fusion-button.button-1 i {color:#ffffff;}.fusion-button.button-1 .fusion-button-icon-divider{border-color:#ffffff;}.fusion-button.button-1:hover .fusion-button-text, .fusion-button.button-1:hover i,.fusion-button.button-1:focus .fusion-button-text, .fusion-button.button-1:focus i,.fusion-button.button-1:active .fusion-button-text, .fusion-button.button-1:active{color:#ffffff;}.fusion-button.button-1:hover .fusion-button-icon-divider, .fusion-button.button-1:hover .fusion-button-icon-divider, .fusion-button.button-1:active .fusion-button-icon-divider{border-color:#ffffff;}.fusion-button.button-1:hover, .fusion-button.button-1:focus, .fusion-button.button-1:active{border-color:#ffffff;}.fusion-button.button-1 {border-color:#ffffff;border-radius:0px;}.fusion-button.button-1{background: #73c221;}.fusion-button.button-1:hover,.button-1:focus,.fusion-button.button-1:active{background: #035ac3;}<\/style><a class=\"fusion-button button-flat button-xlarge button-custom button-1 fusion-button-default-span fusion-button-default-type\" target=\"_self\" href=\"https:\/\/the-three-city-study-3c.com\/\"><span class=\"fusion-button-text\">Accueil<\/span><\/a><\/div><\/div><style type=\"text\/css\">.fusion-body .fusion-builder-column-1{width:25% !important;margin-top : 0px;margin-bottom : 0px;}.fusion-builder-column-1 > .fusion-column-wrapper {padding-top : 0px !important;padding-right : 0px !important;margin-right : 7.68%;padding-bottom : 60px !important;padding-left : 0px !important;margin-left : 7.68%;}@media only screen and (max-width:1024px) {.fusion-body .fusion-builder-column-1{width:100% !important;order : 0;}.fusion-builder-column-1 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}@media only screen and (max-width:640px) {.fusion-body .fusion-builder-column-1{width:100% !important;order : 0;}.fusion-builder-column-1 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}<\/style><\/div><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-2 fusion_builder_column_1_4 1_4 fusion-flex-column\"><div class=\"fusion-column-wrapper fusion-flex-justify-content-flex-start fusion-content-layout-column\" style=\"background-position:left top;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;padding: 0px 0px 0px 0px;\"><div style=\"text-align:center;\"><style type=\"text\/css\">.fusion-button.button-2 .fusion-button-text, .fusion-button.button-2 i {color:#ffffff;}.fusion-button.button-2 .fusion-button-icon-divider{border-color:#ffffff;}.fusion-button.button-2:hover .fusion-button-text, .fusion-button.button-2:hover i,.fusion-button.button-2:focus .fusion-button-text, .fusion-button.button-2:focus i,.fusion-button.button-2:active .fusion-button-text, .fusion-button.button-2:active{color:#ffffff;}.fusion-button.button-2:hover .fusion-button-icon-divider, .fusion-button.button-2:hover .fusion-button-icon-divider, .fusion-button.button-2:active .fusion-button-icon-divider{border-color:#ffffff;}.fusion-button.button-2:hover, .fusion-button.button-2:focus, .fusion-button.button-2:active{border-color:#ffffff;}.fusion-button.button-2 {border-color:#ffffff;border-radius:0px;}.fusion-button.button-2{background: #73c221;}.fusion-button.button-2:hover,.button-2:focus,.fusion-button.button-2:active{background: #035ac3;}<\/style><a class=\"fusion-button button-flat button-xlarge button-custom button-2 fusion-button-default-span fusion-button-default-type\" target=\"_self\" href=\"https:\/\/the-three-city-study-3c.com\/index.php\/about-2\/\"><span class=\"fusion-button-text\">L&rsquo;\u00e9tude<\/span><\/a><\/div><\/div><style type=\"text\/css\">.fusion-body .fusion-builder-column-2{width:25% !important;margin-top : 0px;margin-bottom : 0px;}.fusion-builder-column-2 > .fusion-column-wrapper {padding-top : 0px !important;padding-right : 0px !important;margin-right : 7.68%;padding-bottom : 0px !important;padding-left : 0px !important;margin-left : 7.68%;}@media only screen and (max-width:1024px) {.fusion-body .fusion-builder-column-2{width:100% !important;order : 0;}.fusion-builder-column-2 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}@media only screen and (max-width:640px) {.fusion-body .fusion-builder-column-2{width:100% !important;order : 0;}.fusion-builder-column-2 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}<\/style><\/div><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-3 fusion_builder_column_1_4 1_4 fusion-flex-column\"><div class=\"fusion-column-wrapper fusion-flex-justify-content-flex-start fusion-content-layout-column\" style=\"background-position:left top;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;padding: 0px 0px 0px 0px;\"><div style=\"text-align:left;\"><style type=\"text\/css\">.fusion-button.button-3 .fusion-button-text, .fusion-button.button-3 i {color:#ffffff;}.fusion-button.button-3 .fusion-button-icon-divider{border-color:#ffffff;}.fusion-button.button-3:hover .fusion-button-text, .fusion-button.button-3:hover i,.fusion-button.button-3:focus .fusion-button-text, .fusion-button.button-3:focus i,.fusion-button.button-3:active .fusion-button-text, .fusion-button.button-3:active{color:#ffffff;}.fusion-button.button-3:hover .fusion-button-icon-divider, .fusion-button.button-3:hover .fusion-button-icon-divider, .fusion-button.button-3:active .fusion-button-icon-divider{border-color:#ffffff;}.fusion-button.button-3:hover, .fusion-button.button-3:focus, .fusion-button.button-3:active{border-color:#ffffff;}.fusion-button.button-3 {border-color:#ffffff;border-radius:0px;}.fusion-button.button-3{background: #73c221;}.fusion-button.button-3:hover,.button-3:focus,.fusion-button.button-3:active{background: #035ac3;}<\/style><a class=\"fusion-button button-flat button-xlarge button-custom button-3 fusion-button-default-span fusion-button-default-type\" target=\"_self\" href=\"https:\/\/the-three-city-study-3c.com\/index.php\/equipe\/\"><span class=\"fusion-button-text\">\u00e9quipe scientifique<\/span><\/a><\/div><\/div><style type=\"text\/css\">.fusion-body .fusion-builder-column-3{width:25% !important;margin-top : 0px;margin-bottom : 0px;}.fusion-builder-column-3 > .fusion-column-wrapper {padding-top : 0px !important;padding-right : 0px !important;margin-right : 7.68%;padding-bottom : 0px !important;padding-left : 0px !important;margin-left : 7.68%;}@media only screen and (max-width:1024px) {.fusion-body .fusion-builder-column-3{width:100% !important;order : 0;}.fusion-builder-column-3 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}@media only screen and (max-width:640px) {.fusion-body .fusion-builder-column-3{width:100% !important;order : 0;}.fusion-builder-column-3 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}<\/style><\/div><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-4 fusion_builder_column_1_4 1_4 fusion-flex-column\"><div class=\"fusion-column-wrapper fusion-flex-justify-content-flex-start fusion-content-layout-column\" style=\"background-position:left top;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;padding: 0px 0px 0px 0px;\"><div style=\"text-align:left;\"><style type=\"text\/css\">.fusion-button.button-4 .fusion-button-text, .fusion-button.button-4 i {color:#ffffff;}.fusion-button.button-4 .fusion-button-icon-divider{border-color:#ffffff;}.fusion-button.button-4:hover .fusion-button-text, .fusion-button.button-4:hover i,.fusion-button.button-4:focus .fusion-button-text, .fusion-button.button-4:focus i,.fusion-button.button-4:active .fusion-button-text, .fusion-button.button-4:active{color:#ffffff;}.fusion-button.button-4:hover .fusion-button-icon-divider, .fusion-button.button-4:hover .fusion-button-icon-divider, .fusion-button.button-4:active .fusion-button-icon-divider{border-color:#ffffff;}.fusion-button.button-4:hover, .fusion-button.button-4:focus, .fusion-button.button-4:active{border-color:#ffffff;}.fusion-button.button-4 {border-color:#ffffff;border-radius:0px;}.fusion-button.button-4{background: #73c221;}.fusion-button.button-4:hover,.button-4:focus,.fusion-button.button-4:active{background: #035ac3;}<\/style><a class=\"fusion-button button-flat button-xlarge button-custom button-4 fusion-button-default-span fusion-button-default-type\" target=\"_self\" href=\"https:\/\/the-three-city-study-3c.com\/index.php\/recherches\"><span class=\"fusion-button-text\">Recherches scientifiques<\/span><\/a><\/div><\/div><style type=\"text\/css\">.fusion-body .fusion-builder-column-4{width:25% !important;margin-top : 0px;margin-bottom : 0px;}.fusion-builder-column-4 > .fusion-column-wrapper {padding-top : 0px !important;padding-right : 0px !important;margin-right : 7.68%;padding-bottom : 0px !important;padding-left : 0px !important;margin-left : 7.68%;}@media only screen and (max-width:1024px) {.fusion-body .fusion-builder-column-4{width:100% !important;order : 0;}.fusion-builder-column-4 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}@media only screen and (max-width:640px) {.fusion-body .fusion-builder-column-4{width:100% !important;order : 0;}.fusion-builder-column-4 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}<\/style><\/div><\/div><style type=\"text\/css\">.fusion-body .fusion-flex-container.fusion-builder-row-1{ padding-top : 0px;margin-top : 0px;padding-right : 30px;padding-bottom : 0px;margin-bottom : 0px;padding-left : 30px;}<\/style><\/div><div class=\"fusion-fullwidth fullwidth-box fusion-builder-row-2 fusion-flex-container nonhundred-percent-fullwidth non-hundred-percent-height-scrolling\" style=\"background-color: rgba(255,255,255,0);background-position: center center;background-repeat: no-repeat;border-width: 0px 0px 0px 0px;border-color:#eae9e9;border-style:solid;\" ><div class=\"fusion-builder-row fusion-row fusion-flex-align-items-flex-start\" style=\"max-width:1216.8px;margin-left: calc(-4% \/ 2 );margin-right: calc(-4% \/ 2 );\"><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-5 fusion_builder_column_1_1 1_1 fusion-flex-column\"><div class=\"fusion-column-wrapper fusion-flex-justify-content-flex-start fusion-content-layout-column\" style=\"background-position:left top;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;padding: 0px 0px 0px 0px;\"><div class=\"fusion-text fusion-text-1\"><h2 style=\"text-align: center; color: #73c221;\">Les articles scientifiques<\/h2>\n<\/div><\/div><style type=\"text\/css\">.fusion-body .fusion-builder-column-5{width:100% !important;margin-top : 0px;margin-bottom : 0px;}.fusion-builder-column-5 > .fusion-column-wrapper {padding-top : 0px !important;padding-right : 0px !important;margin-right : 1.92%;padding-bottom : 0px !important;padding-left : 0px !important;margin-left : 1.92%;}@media only screen and (max-width:1024px) {.fusion-body .fusion-builder-column-5{width:100% !important;order : 0;}.fusion-builder-column-5 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}@media only screen and (max-width:640px) {.fusion-body .fusion-builder-column-5{width:100% !important;order : 0;}.fusion-builder-column-5 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}<\/style><\/div><\/div><style type=\"text\/css\">.fusion-body .fusion-flex-container.fusion-builder-row-2{ padding-top : 0px;margin-top : 46px;padding-right : 30px;padding-bottom : 0px;margin-bottom : 0px;padding-left : 30px;}<\/style><\/div><div class=\"fusion-fullwidth fullwidth-box fusion-builder-row-3 fusion-flex-container nonhundred-percent-fullwidth non-hundred-percent-height-scrolling\" style=\"background-color: rgba(255,255,255,0);background-position: center center;background-repeat: no-repeat;border-width: 0px 0px 0px 0px;border-color:#eae9e9;border-style:solid;\" ><div class=\"fusion-builder-row fusion-row fusion-flex-align-items-flex-start\" style=\"max-width:1216.8px;margin-left: calc(-4% \/ 2 );margin-right: calc(-4% \/ 2 );\"><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-6 fusion_builder_column_1_1 1_1 fusion-flex-column\"><div class=\"fusion-column-wrapper fusion-flex-justify-content-flex-start fusion-content-layout-column\" style=\"background-position:left top;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;padding: 0px 0px 85px 0px;\"><style type=\"text\/css\">.fusion-accordian  #accordion-880-1 .panel-title a .fa-fusion-box{ color: #ffffff;}.fusion-accordian  #accordion-880-1 .panel-title a .fa-fusion-box:before{ font-size: 16px; width: 16px;}.fusion-accordian  #accordion-880-1 .panel-title a{font-size:24px;}.fusion-accordian  #accordion-880-1 .fa-fusion-box { background-color: #212934;border-color: #212934;}.fusion-accordian  #accordion-880-1 .panel-title a:hover, #accordion-880-1 .fusion-toggle-boxed-mode:hover .panel-title a { color: #65bc7b;}.fusion-accordian  #accordion-880-1 .panel-title .active .fa-fusion-box,.fusion-accordian  #accordion-880-1 .panel-title a:hover .fa-fusion-box { background-color: #65bc7b!important;border-color: #65bc7b!important;}<\/style><div class=\"accordian fusion-accordian\"><div class=\"panel-group\" id=\"accordion-880-1\"><div class=\"fusion-panel panel-default\"><div class=\"panel-heading\"><h4 class=\"panel-title toggle\"><a aria-expanded=\"false\" aria-controls=\"bcf8c7311d1f1902d\" role=\"button\" data-toggle=\"collapse\" data-parent=\"#accordion-880-1\" data-target=\"#bcf8c7311d1f1902d\" href=\"#bcf8c7311d1f1902d\"><span class=\"fusion-toggle-icon-wrapper\" aria-hidden=\"true\"><i class=\"fa-fusion-box\" aria-hidden=\"true\"><\/i><\/span><span class=\"fusion-toggle-heading\">2002<\/span><\/a><\/h4><\/div><div id=\"bcf8c7311d1f1902d\" class=\"panel-collapse collapse \"><div class=\"panel-body toggle-content fusion-clearfix\">\n<p>Alp\u00e9rovitch A, Amouyel P, Dartigues JF, Ducimeti\u00e8re P, Mazoyer B, Ritchie K, Tzourio C.<strong>\u00a0Epidemiological studies on aging in France: from the PAQUID study to the Three-City study.<\/strong>\u00a0C R Biol. 2002;325(6):665-72. Review. French<\/p>\n<\/div><\/div><\/div><\/div><\/div><style type=\"text\/css\">.fusion-accordian  #accordion-880-2 .panel-title a .fa-fusion-box{ color: #ffffff;}.fusion-accordian  #accordion-880-2 .panel-title a .fa-fusion-box:before{ font-size: 16px; width: 16px;}.fusion-accordian  #accordion-880-2 .panel-title a{font-size:24px;}.fusion-accordian  #accordion-880-2 .fa-fusion-box { background-color: #212934;border-color: #212934;}.fusion-accordian  #accordion-880-2 .panel-title a:hover, #accordion-880-2 .fusion-toggle-boxed-mode:hover .panel-title a { color: #65bc7b;}.fusion-accordian  #accordion-880-2 .panel-title .active .fa-fusion-box,.fusion-accordian  #accordion-880-2 .panel-title a:hover .fa-fusion-box { background-color: #65bc7b!important;border-color: #65bc7b!important;}<\/style><div class=\"accordian fusion-accordian\"><div class=\"panel-group\" id=\"accordion-880-2\"><div class=\"fusion-panel panel-default\"><div class=\"panel-heading\"><h4 class=\"panel-title toggle\"><a aria-expanded=\"false\" aria-controls=\"b40fa044b7f0dea29\" role=\"button\" data-toggle=\"collapse\" data-parent=\"#accordion-880-2\" data-target=\"#b40fa044b7f0dea29\" href=\"#b40fa044b7f0dea29\"><span class=\"fusion-toggle-icon-wrapper\" aria-hidden=\"true\"><i class=\"fa-fusion-box\" aria-hidden=\"true\"><\/i><\/span><span class=\"fusion-toggle-heading\">2003<\/span><\/a><\/h4><\/div><div id=\"b40fa044b7f0dea29\" class=\"panel-collapse collapse \"><div class=\"panel-body toggle-content fusion-clearfix\">\n<div class=\"cms_bloc cms_bloc_text\">\n<p>The 3C Study Group. Vascular factors and risk of dementia.\u00a0<strong>Design of the Three-City Study and baseline characteristics of the study population.<\/strong>\u00a0<em>Neuroepidemiology<\/em>. 2003; 22:316-325.<\/p>\n<\/div>\n<div class=\"spacer\"><\/div>\n<div class=\"cms_bloc cms_bloc_text\"><\/div>\n<\/div><\/div><\/div><\/div><\/div><style type=\"text\/css\">.fusion-accordian  #accordion-880-3 .panel-title a .fa-fusion-box{ color: #ffffff;}.fusion-accordian  #accordion-880-3 .panel-title a .fa-fusion-box:before{ font-size: 16px; width: 16px;}.fusion-accordian  #accordion-880-3 .panel-title a{font-size:24px;}.fusion-accordian  #accordion-880-3 .fa-fusion-box { background-color: #212934;border-color: #212934;}.fusion-accordian  #accordion-880-3 .panel-title a:hover, #accordion-880-3 .fusion-toggle-boxed-mode:hover .panel-title a { color: #65bc7b;}.fusion-accordian  #accordion-880-3 .panel-title .active .fa-fusion-box,.fusion-accordian  #accordion-880-3 .panel-title a:hover .fa-fusion-box { background-color: #65bc7b!important;border-color: #65bc7b!important;}<\/style><div class=\"accordian fusion-accordian\"><div class=\"panel-group\" id=\"accordion-880-3\"><div class=\"fusion-panel panel-default\"><div class=\"panel-heading\"><h4 class=\"panel-title toggle\"><a aria-expanded=\"false\" aria-controls=\"b3c05d69e47bbd850\" role=\"button\" data-toggle=\"collapse\" data-parent=\"#accordion-880-3\" data-target=\"#b3c05d69e47bbd850\" href=\"#b3c05d69e47bbd850\"><span class=\"fusion-toggle-icon-wrapper\" aria-hidden=\"true\"><i class=\"fa-fusion-box\" aria-hidden=\"true\"><\/i><\/span><span class=\"fusion-toggle-heading\">2004<\/span><\/a><\/h4><\/div><div id=\"b3c05d69e47bbd850\" class=\"panel-collapse collapse \"><div class=\"panel-body toggle-content fusion-clearfix\">\n<p>Larrieu S, Letenneur L, Berr C, Dartigues JF, Ritchie K, Alp\u00e9rovitch A, Tavernier B, Barberger-Gateau P.\u00a0<strong>Sociodemographic differences in dietary habits in a population-based sample of elderly subjects in the 3C Study.<\/strong>\u00a0<em>J Nutr Health Aging<\/em>\u00a02004; 8:497-502.<\/p>\n<p>Larrieu S, P\u00e9r\u00e8s K, Letenneur L, Berr C, Dartigues JF, Ritchie K, F\u00e9vrier B, Alp\u00e9rovitch A, Barberger-Gateau P.\u00a0<strong>Relationship between body mass index and different domains of disability in older persons: The 3C Study.<\/strong>\u00a0<em>Int J Obes Relat Metab Disord<\/em>\u00a02004; 28:1555-60.<\/p>\n<p>Ritchie K, Artero S, Beluche I, Ancelin ML, Mann A, Dupuy AM, Malafosse A, Boulenger JP.<strong>\u00a0Prevalence of DSM-IV psychiatric disorder in the French elderly population.\u00a0<\/strong>Br J Psychiatry. 2004 Feb;184:147-52. (Esprit cohort, subgroup of Montpellier 3C).<\/p>\n<p>Zureik M, Gari\u00e9py J, Courbon D, Dartigues JF, Ritchie K, Tzourio C,<br \/>\nAlp\u00e9rovitch A, Simon A, Ducimeti\u00e8re P.\u00a0<strong>Alcohol consumption and large artery structure in older French adults.<\/strong>\u00a0The Three-City Study.\u00a0<em>Stroke<\/em>\u00a02004; 35:2770-2775.<\/p>\n<\/div><\/div><\/div><\/div><\/div><style type=\"text\/css\">.fusion-accordian  #accordion-880-4 .panel-title a .fa-fusion-box{ color: #ffffff;}.fusion-accordian  #accordion-880-4 .panel-title a .fa-fusion-box:before{ font-size: 16px; width: 16px;}.fusion-accordian  #accordion-880-4 .panel-title a{font-size:24px;}.fusion-accordian  #accordion-880-4 .fa-fusion-box { background-color: #212934;border-color: #212934;}.fusion-accordian  #accordion-880-4 .panel-title a:hover, #accordion-880-4 .fusion-toggle-boxed-mode:hover .panel-title a { color: #65bc7b;}.fusion-accordian  #accordion-880-4 .panel-title .active .fa-fusion-box,.fusion-accordian  #accordion-880-4 .panel-title a:hover .fa-fusion-box { background-color: #65bc7b!important;border-color: #65bc7b!important;}<\/style><div class=\"accordian fusion-accordian\"><div class=\"panel-group\" id=\"accordion-880-4\"><div class=\"fusion-panel panel-default\"><div class=\"panel-heading\"><h4 class=\"panel-title toggle\"><a aria-expanded=\"false\" aria-controls=\"03699bcf43e1d4ca8\" role=\"button\" data-toggle=\"collapse\" data-parent=\"#accordion-880-4\" data-target=\"#03699bcf43e1d4ca8\" href=\"#03699bcf43e1d4ca8\"><span class=\"fusion-toggle-icon-wrapper\" aria-hidden=\"true\"><i class=\"fa-fusion-box\" aria-hidden=\"true\"><\/i><\/span><span class=\"fusion-toggle-heading\">2005<\/span><\/a><\/h4><\/div><div id=\"03699bcf43e1d4ca8\" class=\"panel-collapse collapse \"><div class=\"panel-body toggle-content fusion-clearfix\">\n<p>Barberger-Gateau P, Jutand MA, Letenneur L, Larrieu S, Berr C, Tavernier B and the Three-City Study Investigators.\u00a0<strong>Correlates of regular fish consumption in French elderly community dwellers: data from the Three-City study.<\/strong>\u00a0<em>Eur J Clin Nutrition<\/em>\u00a02005; 59:817-825.<\/p>\n<p>Cowppli-Bony P, Fabrigoule C, Letenneur et al.\u00a0<strong>Validity of the five-word screening test for Alzheimer\u2019s disease in a population-based study.<\/strong>\u00a0<em>Rev Neurol<\/em>\u00a0(Paris) 2005; 161:1205-1212.<\/p>\n<p>De Bisschop C, Marty ML, Tessier JF, Barberger-Gateau P, Dartigues JF, Gu\u00e9nard H.\u00a0<strong>Expiratory flow limitation and obstruction in the elderly.<\/strong>\u00a0<em>Eur Respir J<\/em>\u00a02005; 26:594-601.<\/p>\n<p>Dufouil C*, Richard F*, Fi\u00e9vet N, Dartigues JF, Ritchie K, Tzourio C, Amouyel P, Alp\u00e9rovitch A. A<strong>POE genotype, cholesterol level, lipid-lowering treatment and dementia. The Three-City Study.<\/strong>\u00a0<em>Neurology<\/em>\u00a02005; 64:1531-1538.<\/p>\n<p>Elbaz A, Ripert M, Tavernier B, F\u00e9vrier B, Zureik M, Gari\u00e9py J, Alp\u00e9rovitch A, Tzourio C.\u00a0<strong>Common carotid artery intima-media thickness, carotid plaques, and walking speed.<\/strong>\u00a0<em>Stroke<\/em>\u00a02005; 36:2198-2202.<\/p>\n<p>Feart C, Pallet V, Boucheron C, Higueret D, Alfos S, Letenneur L, Dartigues JF, Higueret P.\u00a0<strong>Aging affects the retinoic acid and the triiodothyronine nuclear receptor mRNA expression in human peripheral blood mononuclear cells.<\/strong>Eur J Endocrinol 2005 Mar;152(3):449-58<\/p>\n<p>Lechevallier-Michel N, Gautier-Bertrand M, Alp\u00e9rovitch A, Berr C, Belmin J, Legrain S, Saint-Jean O, Tavernier B, Dartigues JF, Fourrier-R\u00e9galat A.\u00a0<strong>Frequency and risk factors of potentially inappropriate medication use in a French community-dwelling elderly population: Results from the 3C Study.<\/strong>\u00a0<em>Eur J Clin Pharmacol<\/em>\u00a02005; 60:813-819.<\/p>\n<\/div><\/div><\/div><\/div><\/div><style type=\"text\/css\">.fusion-accordian  #accordion-880-5 .panel-title a .fa-fusion-box{ color: #ffffff;}.fusion-accordian  #accordion-880-5 .panel-title a .fa-fusion-box:before{ font-size: 16px; width: 16px;}.fusion-accordian  #accordion-880-5 .panel-title a{font-size:24px;}.fusion-accordian  #accordion-880-5 .fa-fusion-box { background-color: #212934;border-color: #212934;}.fusion-accordian  #accordion-880-5 .panel-title a:hover, #accordion-880-5 .fusion-toggle-boxed-mode:hover .panel-title a { color: #65bc7b;}.fusion-accordian  #accordion-880-5 .panel-title .active .fa-fusion-box,.fusion-accordian  #accordion-880-5 .panel-title a:hover .fa-fusion-box { background-color: #65bc7b!important;border-color: #65bc7b!important;}<\/style><div class=\"accordian fusion-accordian\"><div class=\"panel-group\" id=\"accordion-880-5\"><div class=\"fusion-panel panel-default\"><div class=\"panel-heading\"><h4 class=\"panel-title toggle\"><a aria-expanded=\"false\" aria-controls=\"21079ab1100c4467f\" role=\"button\" data-toggle=\"collapse\" data-parent=\"#accordion-880-5\" data-target=\"#21079ab1100c4467f\" href=\"#21079ab1100c4467f\"><span class=\"fusion-toggle-icon-wrapper\" aria-hidden=\"true\"><i class=\"fa-fusion-box\" aria-hidden=\"true\"><\/i><\/span><span class=\"fusion-toggle-heading\">2006<\/span><\/a><\/h4><\/div><div id=\"21079ab1100c4467f\" class=\"panel-collapse collapse \"><div class=\"panel-body toggle-content fusion-clearfix\">\n<p>Artero S, Astruc B, Courtet P, Ritchie K.\u00a0<strong>Life-time history of suicide attempts and coronary artery disease in a community-dwelling elderly population.<\/strong>\u00a0<em>International Journal of Geriatric Psychiatry<\/em>\u00a02006; 21:108-112.<\/p>\n<p>Brindel P, Hanon O,\u00a0 Dartigues JF, Ritchie K, Lacombe JM, Alp\u00e9rovitch A, Tzourio C for the 3C Study investigators.\u00a0<strong>Prevalence, awareness, treatment and control of hypertension in the elderly. The Three-City Study.<\/strong>\u00a0<em>J Hypertension<\/em>\u00a02006; 24:51-58.<\/p>\n<p>Debette S, Lambert JC, Gari\u00e9py J, Fievet N, Tzourio C, Dartigues JF, Ritchie K, Dupuy AM, Alp\u00e9rovitch A, Ducimeti\u00e8re P, Amouyel P, Zureik M.\u00a0<strong>New insight into the association of apoE genetic variants with carotid plaques and intima-media thickness.<\/strong>\u00a0<em>Stroke<\/em>\u00a02006; 37:2917-2923.<\/p>\n<p>Harrabi I, Rondeau V, Dartigues JF et al.\u00a0<strong>Effects of particulate air pollution on systolic blood pressure:A population-based approach.<\/strong>\u00a0<em>Environ Res<\/em>\u00a02006; 101:89-93.<\/p>\n<p>Soumar\u00e9 A, Elbaz E, Ducros V, Tavernier B, Alp\u00e9rovitch A ,Tzourio C.\u00a0<strong>Homocysteine and the motor function in the elderly \u2013 The Three-City Study.<\/strong>\u00a0<em>Neurology<\/em>\u00a02006; 67:285-290.<\/p>\n<\/div><\/div><\/div><\/div><\/div><style type=\"text\/css\">.fusion-accordian  #accordion-880-6 .panel-title a .fa-fusion-box{ color: #ffffff;}.fusion-accordian  #accordion-880-6 .panel-title a .fa-fusion-box:before{ font-size: 16px; width: 16px;}.fusion-accordian  #accordion-880-6 .panel-title a{font-size:24px;}.fusion-accordian  #accordion-880-6 .fa-fusion-box { background-color: #212934;border-color: #212934;}.fusion-accordian  #accordion-880-6 .panel-title a:hover, #accordion-880-6 .fusion-toggle-boxed-mode:hover .panel-title a { color: #65bc7b;}.fusion-accordian  #accordion-880-6 .panel-title .active .fa-fusion-box,.fusion-accordian  #accordion-880-6 .panel-title a:hover .fa-fusion-box { background-color: #65bc7b!important;border-color: #65bc7b!important;}<\/style><div class=\"accordian fusion-accordian\"><div class=\"panel-group\" id=\"accordion-880-6\"><div class=\"fusion-panel panel-default\"><div class=\"panel-heading\"><h4 class=\"panel-title toggle\"><a aria-expanded=\"false\" aria-controls=\"af13c35c0014141fb\" role=\"button\" data-toggle=\"collapse\" data-parent=\"#accordion-880-6\" data-target=\"#af13c35c0014141fb\" href=\"#af13c35c0014141fb\"><span class=\"fusion-toggle-icon-wrapper\" aria-hidden=\"true\"><i class=\"fa-fusion-box\" aria-hidden=\"true\"><\/i><\/span><span class=\"fusion-toggle-heading\">2007<\/span><\/a><\/h4><\/div><div id=\"af13c35c0014141fb\" class=\"panel-collapse collapse \"><div class=\"panel-body toggle-content fusion-clearfix\">\n<p>Amieva H, Carcaillon L, Rouze L&rsquo;Alzit-Schuermans P, Millet X, Dartigues JF, Fabrigoule C.<strong>\u00a0Cued and uncued memory tests: norms in elderly adults from the 3 Cities epidemiological study.<\/strong>Rev Neurol (Paris). 2007;163(2):205-21. French<\/p>\n<p>Barberger-Gateau P, Raffaitin C, Letenneur L, Berr C, Tzourio C, Dartigues JF, Alp\u00e9rovitch A.\u00a0<strong>Dietary patterns and risk of dementia: the Three-City cohort study.<\/strong>\u00a0<em>Neurology<\/em>\u00a02007; 69:1921-1930.<\/p>\n<p>Bourdel-Marchasson I, Helmer C, Barberger-Gateau P, Peuchant E, F\u00e9vrier B, Ritchie K, Dartigues JF.\u00a0<strong>Characteristics of undiagnosed diabetes in community dwelling French elderly: The 3C study.<\/strong>\u00a0D<em>iabetes Research and Clinical Practice<\/em>\u00a02007; 76:257-264.<\/p>\n<p>Empana JP, Zureik M, Gari\u00e9py J, Courbon D, Dartigues JF, Ritchie K, Tzourio C, Alp\u00e9rovitch A, Ducimeti\u00e8re P.\u00a0<strong>Metabolic syndrome and carotid artery structure in non-institutionalized elderly subjects-The Three-City Study.<\/strong>\u00a0<em>Stroke<\/em>\u00a02007; 38:893-899.<\/p>\n<p>Feart C, Jutand MA, Larrieu S, Letenneur L, Delcourt C, Combe C, Barberger-Gateau P.\u00a0<strong>Energy, macronutrient and fatty acid intake of French elderly community dwellers and association with socio-demographic characteristics: data from the 3C-Bordeaux sample of the Three-City Study.<\/strong>\u00a0<em>Br J Nutrition<\/em>\u00a02007; 98:1046-1057.<\/p>\n<p>Godin O, Dufouil C, Ritchie K, Dartigues JF, Tzourio C, Alp\u00e9rovitch A.\u00a0<strong>Depressive symptoms, major depressive episode and cognition il the elderly: the Three-City Study.<\/strong>\u00a0<em>Neuroepidemiology<\/em>\u00a02007; 28:101-108.<\/p>\n<p>Ritchie K, Carri\u00e8re I, Portet F, de Mendoca A, Dartigues JF, Rouaud 0, Barberger-Gateau P, Ancelin, ML.\u00a0<strong>The neuroprotective effect of caffeine: a prospective population study (The Three City Study).<\/strong>\u00a0<em>Neurology<\/em>\u00a02007; 69:536-545.<\/p>\n<p>Tsuno N, Jaussent I, Dauvilliers Y, Touchon J, Ritchie K, Besset A.\u00a0<strong>Determinants of excessive daytime sleepiness in a French community-dwelling population.\u00a0<\/strong>\u00a0<em>J Sleep Res<\/em>\u00a02007; 16:364-371.<\/p>\n<\/div><\/div><\/div><\/div><\/div><style type=\"text\/css\">.fusion-accordian  #accordion-880-7 .panel-title a .fa-fusion-box{ color: #ffffff;}.fusion-accordian  #accordion-880-7 .panel-title a .fa-fusion-box:before{ font-size: 16px; width: 16px;}.fusion-accordian  #accordion-880-7 .panel-title a{font-size:24px;}.fusion-accordian  #accordion-880-7 .fa-fusion-box { background-color: #212934;border-color: #212934;}.fusion-accordian  #accordion-880-7 .panel-title a:hover, #accordion-880-7 .fusion-toggle-boxed-mode:hover .panel-title a { color: #65bc7b;}.fusion-accordian  #accordion-880-7 .panel-title .active .fa-fusion-box,.fusion-accordian  #accordion-880-7 .panel-title a:hover .fa-fusion-box { background-color: #65bc7b!important;border-color: #65bc7b!important;}<\/style><div class=\"accordian fusion-accordian\"><div class=\"panel-group\" id=\"accordion-880-7\"><div class=\"fusion-panel panel-default\"><div class=\"panel-heading\"><h4 class=\"panel-title toggle\"><a aria-expanded=\"false\" aria-controls=\"eee7783d98efae95f\" role=\"button\" data-toggle=\"collapse\" data-parent=\"#accordion-880-7\" data-target=\"#eee7783d98efae95f\" href=\"#eee7783d98efae95f\"><span class=\"fusion-toggle-icon-wrapper\" aria-hidden=\"true\"><i class=\"fa-fusion-box\" aria-hidden=\"true\"><\/i><\/span><span class=\"fusion-toggle-heading\">2008<\/span><\/a><\/h4><\/div><div id=\"eee7783d98efae95f\" class=\"panel-collapse collapse \"><div class=\"panel-body toggle-content fusion-clearfix\">\n<p>Artero S, Ancelin M-L, Portet F, Dupuy ,\u00a0 Berr C , Dartigues J-F, Tzourio C, Rouaud O, Poncet M, Pasquier F , Auriacombe S, Touchon J, Ritchie K .\u00a0<strong>Risk profiles for Mild Cognitive Impairment and progression to dementia are gender specific.<\/strong>\u00a0<em>Journal of Neurology, Neurosurgery and Psychiatry<\/em>\u00a02008; 79:979-984.<\/p>\n<p>Avila-Funes JA, Helmer C, Amieva H, Barberger-Gateau P, Le Goff M, Ritchie K, Portet F, Carri\u00e8re I, Tavernier B, Gutrti\u00e9rez-Robledo LM, Dartigues, JF.\u00a0<strong>Frailty among community-dwelling elderly people in France: the three-city study.<\/strong>\u00a0<em>J Gerontol A Biol Sci Med Sci<\/em>\u00a02008; 63:1089-1096<\/p>\n<p>Ben Salem D, Walker PM, Aho S, Tavernier B, Giroud M, Tzourio C, Ricolfi F, Brunotte F.\u00a0<strong>Brain flexibility and balance and gait performances mark morphological and metabolic abnormalities in the elderly.<\/strong>\u00a0<em>J Clin Neurosci<\/em>. 2008 Dec;15(12):1360-5. Epub 2008 Oct 26<\/p>\n<p>Ben Salem D, Walker PM, Bejot Y, Aho SL, Tavernier B, Rouaud O, Ricolfi F, Brunotte F.\u00a0<strong>N-acetylaspartate\/creatine and choline\/creatine ratios in the thalami, insular cortex and white matter as markers of hypertension and cognitive impairment in the elderly.<\/strong>\u00a0<em>Hypertens Res<\/em>. 2008;31(10):1851-7<\/p>\n<p>Bruandet A, Richard F, Tzourio C, Berr C, Dartigues Jf, Alperovitch A, Amouyel P, Helbecque N.\u00a0<strong>Haplotypes across ACE and the risk of Alzheimer disease. The Three-City Study.<\/strong>\u00a0<em>J Alz Disease<\/em>\u00a02008; 13:333-339.<\/p>\n<p>Chaudieu I*, Beluche I*, Norton J, Boulenger JP, Ritchie K, Ancelin ML.\u00a0<strong>Abnormal reactions to environmental stress in elderly persons with anxiety disorders:evidence from a population study of diurnal cortisol changes.\u00a0\u00a0<\/strong><em>Journal of Affective Disorders<\/em>\u00a02008; 106:307-313.<\/p>\n<p>Debette S, Courbon D, Leone N, Gari\u00e9py J, Tzourio C, Dartigues JF, Barberger-Gateau P, Ritchie K, Alp\u00e9rovitch A, Amouyel P, Ducimeti\u00e8re P, Zureik M.\u00a0<strong>Tea consumption is inversely associated with carotid plaques in women.<\/strong>\u00a0<em>Arterioscl Thromb Vasc Biol<\/em>\u00a02008; 28:353-359.<\/p>\n<p>Debette S, Leone N, Courbon D, Gari\u00e9py J, Tzourio C, Dartigues JF, Ritchie K, Alp\u00e9rovitch A, Ducimeti\u00e8re P, Amouyel P, Zureik M.<strong>\u00a0Calf circumference is inversely associated with carotid plaques.<\/strong>\u00a0<em>Stroke<\/em>\u00a02008; 39:2958-2965<\/p>\n<p>Dupuy AM, Carri\u00e8re I, Scali J, Cristol JP, Ritchie K, Dartigues JF, Gambert P, Ancelin ML.\u00a0<strong>Lipid levels and cardiovascular risk in elderly women:a general population study of the effects of hormonal treatment and lipid-lowering agents.<\/strong>\u00a0<em>Climacteric<\/em>\u00a02008; 11:74-83.<\/p>\n<p>Feart C, Peuchant E, Letenneur L, Samieri C, Montagnier D, Fourrier-Reglat A, Barberger-Gateau P.\u00a0<strong>Plasma eicosapentaenoic acid (EPA) is inversely associated with severity of depressive symptomatology in the elderly: data from the Bordeaux sample of the Three-City study.<\/strong>\u00a0<em>American Journal of Clinical Nutrition<\/em>\u00a02008; 87:1156-1162.<\/p>\n<p>Godin O, Dufouil C, Maillard P, Delcroix N, Mazoyer B, Crivello F, Alp\u00e9rovitch A, Tzourio C.\u00a0<strong>White matter lesions as a predictor of depression in the elderly- The 3C-Dijon study.<\/strong>\u00a0<em>Biological Psychiatry<\/em>\u00a02008; 63:663-669.<\/p>\n<p>Helmer C, P\u00e9r\u00e8s K, Pariente A, Pasquier F, Auriacombe S, Poncet M, Portet F, Rouaud O, Ritchie K, Tzourio C, Dartigues JF.\u00a0<strong>Primary and secondary care consultations in elderly demented individuals in France. Results from the Three-City Study.\u00a0<\/strong><em>Dement Geriatr Cogn Disord<\/em>. 2008; 26(5):407-15.<\/p>\n<p>Helmer C, Bricout H, Gin H, Barberger-Gateau P.\u00a0<strong>Macronutrient intake and discrepancy with nutritional recommendations in a group of elderly diabetic subjects.\u00a0<\/strong><em>Br J Nutr<\/em>. 2008; 99:632-638.<\/p>\n<p>Lafont S, Laumon B, Helmer C, Dartigues JF, Fabrigoule C.\u00a0<strong>Driving cessation and self-reported car crashes in older drivers: the impact of cognitive impairment and dementia in a population-based study.<\/strong>\u00a0<em>J Geriatr Psychiatry Neurology<\/em>\u00a02008; 21:171-182.<\/p>\n<p>Larrieu S, Carcaillon L, Lefranc A, Helmer C, Dartigues JF, Tavernier B, Ledrans M, Filleul M.\u00a0<strong>Factors associated with morbidity during the 2003 heat wave in two population-based cohort of elderly subjects:PAQUID and the Three-City Study.<\/strong>\u00a0\u00a0<em>Eur J Epidemiol<\/em>\u00a02008; 23:295-302.<\/p>\n<p>Lenoir H, Lacombe JM, Dufouil C, Ducimeti\u00e8re P, Hanon O, Ritchie K, Dartigues JF, Alp\u00e9rovitch A, Tzourio C.\u00a0<strong>Relationship between blood pressure and depression in the elderly.<\/strong>\u00a0<strong>The Three-City (3C)<\/strong>\u00a0Study.\u00a0<em>J Hypertension<\/em>\u00a02008; 26:1765-1772.<\/p>\n<p>Leone N , Ducimeti\u00e8re P, Gari\u00e9py J, Courbon D, Tzourio C, Dartigues JF, Tzourio C, Alp\u00e9rovitch A, Amouyel P, Safar ME, Zureik M.\u00a0<strong>Distension of carotid artery and risk of coronary events \u2013 The Three-City study.<\/strong>\u00a0<em>Arterioscl Thromb Vasc Biol<\/em>\u00a02008; 1392-1397.<\/p>\n<p>Maillard P,\u00a0 Delcroix N, Crivello F, Dufouil C, Gicquel S, Joliot M, Tzourio-Mazoyer N, Alp\u00e9rovitch A, Tzourio C,\u00a0 Mazoyer M.\u00a0<strong>An automated procedure for the assessment of white matter hyperintensities on multispectral (T1, T2, PD) MRI and its between-centre reproducibility evaluation on two large community databases.<\/strong>\u00a0<em>Neuroradiology<\/em>\u00a02008; 50:31-42.<\/p>\n<p>Ryan J, Carri\u00e8re I, Ritchie K, Stewart R, Toulemonde G, Dartigues JF, Tzourio C, Ancelin ML.\u00a0<strong>Late-life depression, gender and mortality:the influence of gender and antidepressant use.<\/strong>\u00a0<em>British J Psychiatry<\/em>\u00a02008; 192:10-18.<\/p>\n<p>Ryan J, Carri\u00e8re I., Scali J. Ritchie K. and Ancelin M.L.\u00a0\u00a0<strong>Lifetime hormonal factors may predict late-life depression in women.<\/strong>\u00a0<em>International Psychogeriatrics<\/em>\u00a02008; 20:1203-1218.<\/p>\n<p>Samieri C, F\u00e9art C, Letenneur L, Dartigues J-F, P\u00e9r\u00e8s K,\u00a0 Auriacombe S, Peuchant E, Delcourt C, Barberger-Gateau P.\u00a0<strong>Low plasma eicosapentaenoic acid (EPA) and depressive symptomatology are independent predictors of dementia risk.<\/strong>\u00a0<em>American Journal of Clinical Nutrition<\/em>\u00a02008; 88: 714-721.<\/p>\n<p>Samieri C, Jutand MA, F\u00e9art C,\u00a0 Capuron L, Letenneur L, Barberger-Gateau P.\u00a0<strong>Dietary patterns derived by hybrid clustering method in older persons: association with cognition, mood and self-rated health.<\/strong>\u00a0<em>Journal of the American Dietetic Association<\/em>\u00a02008; 108(9):1461-1471.<\/p>\n<p>Soudry A, Dufouil C, Ritchie K, Dartigues JF, Tzourio C, Alp\u00e9rovitch A.\u00a0<strong>Factors associated with change in antidepressant use in a community-dwelling elderly cohort.<\/strong>\u00a0<em>Eur J Clin Pharmacol<\/em>\u00a02008; 64:51-59.<\/p>\n<p>Soudry A, Dufouil C, Ritchie K, Dartigues JF, Tzourio C, Alp\u00e9rovitch A.\u00a0<strong>Factors associated with antidepressant use in depressed and non depressed community-dwelling elderly.<\/strong>\u00a0<em>Int J Geriatr Psychiatry\u00a0<\/em>2008; 23: 324-30.<\/p>\n<p>Stewart R, Dufouil C, Godin O, Ritchie K, Maillard P, Delcroix N, Crivello F, Mazoyer B, Tzourio C.\u00a0<strong>Neuroimaging correlates of subjective memory deficits in a community population.<\/strong>\u00a0<em>Neurology<\/em>\u00a02008; 70:1601-1607.<\/p>\n<p>Vidal JS, Dufouil C, Ducros V, Tzourio C.\u00a0<strong>Homocysteine, Folate and Cognition in a Large Community-Based Sample of Elderly People &#8211; The 3C Dijon Study.<\/strong>\u00a0<em>Neuroepidemiology<\/em>\u00a02008; 30:207-214.<\/p>\n<\/div><\/div><\/div><\/div><\/div><style type=\"text\/css\">.fusion-accordian  #accordion-880-8 .panel-title a .fa-fusion-box{ color: #ffffff;}.fusion-accordian  #accordion-880-8 .panel-title a .fa-fusion-box:before{ font-size: 16px; width: 16px;}.fusion-accordian  #accordion-880-8 .panel-title a{font-size:24px;}.fusion-accordian  #accordion-880-8 .fa-fusion-box { background-color: #212934;border-color: #212934;}.fusion-accordian  #accordion-880-8 .panel-title a:hover, #accordion-880-8 .fusion-toggle-boxed-mode:hover .panel-title a { color: #65bc7b;}.fusion-accordian  #accordion-880-8 .panel-title .active .fa-fusion-box,.fusion-accordian  #accordion-880-8 .panel-title a:hover .fa-fusion-box { background-color: #65bc7b!important;border-color: #65bc7b!important;}<\/style><div class=\"accordian fusion-accordian\"><div class=\"panel-group\" id=\"accordion-880-8\"><div class=\"fusion-panel panel-default\"><div class=\"panel-heading\"><h4 class=\"panel-title toggle\"><a aria-expanded=\"false\" aria-controls=\"28c0a55b082340abf\" role=\"button\" data-toggle=\"collapse\" data-parent=\"#accordion-880-8\" data-target=\"#28c0a55b082340abf\" href=\"#28c0a55b082340abf\"><span class=\"fusion-toggle-icon-wrapper\" aria-hidden=\"true\"><i class=\"fa-fusion-box\" aria-hidden=\"true\"><\/i><\/span><span class=\"fusion-toggle-heading\">2009<\/span><\/a><\/h4><\/div><div id=\"28c0a55b082340abf\" class=\"panel-collapse collapse \"><div class=\"panel-body toggle-content fusion-clearfix\">\n<div class=\"cms_bloc cms_bloc_text\">\n<p>Akbaraly TN, Portet F, Fustinoni S, Dartigues JF, Artero S, Rouaud O, Touchon J, Ritchie K, Berr C..\u00a0\u00a0<strong>Leisure activity and risk of dementia: results from the Three-City Study.<\/strong>\u00a0<em>Neurology<\/em>2009; 73:854-61<\/p>\n<p>Alp\u00e9rovitch A, Lacombe JM, Hanon O, Dartigues JF, Ritchie K, Ducimeti\u00e8re P, Tzourio C.\u00a0<strong>Relation of blood pressure and outdoor temperature in large sample of elderly individuals.<\/strong>\u00a0<em>Archives of Internal Medecine\u00a0<\/em>2009; 169:75-80<\/p>\n<p>Alp\u00e9rovitch A, Bertrand M, Jougla E, Vidal JS, Ducimeti\u00e8re P, Helmer C, Ritchie K, Pavillon G, Tzourio C. Do we really know the cause of death of the very old\u00a0?\u00a0<strong>Comparison between official mortality statistics and cohort study classification.<\/strong>\u00a0<em>Eur J Epidemiol<\/em>. 2009; 24:669-675]\n<p>Avila-Funes JA, Amieva H, Barberger-Gateau P, Le Goff M, Raoux N, Ritchie K, Carriere I, Tavernier B, Tzourio C, Gutierrez-Robledo LM, Dartigues JF.\u00a0<strong>Cognitive Impairment Improves the Predictive Validity of the Phenotype of Frailty for Adverse Health Outcomes: The Three-City Study.<\/strong>\u00a0J<em>ournal of the American Geriatrics Society<\/em>\u00a02009; 57:453-61.<\/p>\n<p>Beluche I*, Chaudieu*, Norton J, Carri\u00e8re I, Boulenger JP, Ritchie K, Ancelin ML.\u00a0<strong>Persistence of abnormal cortisol levels in elderly depressed persons after recovery from major depression.<\/strong>\u00a0<em>Journal of Psychiatric Research<\/em>\u00a02009; 43:773-783<\/p>\n<p>Berdot S, Bertrand M, Dartigues JF, Fourrier A, Tavernier B, Ritchie K, Alp\u00e9rovitch A.\u00a0<strong>Inappropriate medication use and risk of falls \u2013 a prospective study in a large community-dwelling elderly cohort.\u00a0<\/strong><em>BMC Geriatr<\/em>. 2009 Jul 23 9: 30.<\/p>\n<p><span class=\"rprtbody\">Berr C, Portet F, Carriere I, Akbaraly T, Feart C, Gourlet V, Combe N, Barberger-Gateau P, Ritchie K.\u00a0<strong>Olive oil and cognition: the Three-City cohort study.<\/strong>\u00a0<em>Dem Ger Cog Dis<\/em>\u00a02009; 28; 357-364<\/span><\/p>\n<p>Bineau S, Dufouil C, Helmer C, Ritchie K, Empana JP, Ducimeti\u00e8re P, Alp\u00e9rovitch A, Bousser MG, Tzourio C.\u00a0<strong>Framingham stroke risk function in a large population-based cohort of elderly people: the 3C Study.<\/strong>\u00a0<em>Stroke<\/em>\u00a02009; 40:1564-1570<\/p>\n<p>Buyck JF, Dufouil C, Ducimeti\u00e8re P, Alp\u00e9rovitch A, Bousser MG, Kurth T, Tzourio C.\u00a0<strong>Cerebral white matter lesions are associated with the risk of stroke but not with other vascular events. The 3C-Dijon Study.<\/strong>\u00a0<em>Stroke<\/em>\u00a02009; 40:2327-2331<\/p>\n<p><span class=\"rprtbody\">Capuron L, Moranis A, Combe N, Cousson-G\u00e9lie F, Fuchs D, De Smedt-Peyrusse V, Barberger-Gateau P, Lay\u00e9 S.\u00a0<strong>Vitamine E status and quality of life in the elderly: influence of inflammatory processes.<\/strong>\u00a0<em>Br J Nutrition<\/em>\u00a02009; 102:1390-94<\/span><\/p>\n<p>Carcaillon L, Amieva H, Auriacombe S, Helmer C, Dartigues JF. A subtest of the MMSE as a valid test of episodic memory?\u00a0<strong>Comparison with the Free and Cued Reminding Test.<\/strong>\u00a0D<em>ement Geriatr Cogn Disord<\/em>. 2009; 27:429-38.<\/p>\n<p><span class=\"rprtbody\">Carcaillon L, Gaussem P, Ducimeti\u00e8re P, Giroud M, Ritchie K, Scarabin PY.\u00a0<strong>Elevated plasma fibrin D-dimer as a risk factor for vascular dementia: the Three-City cohort study<\/strong><em><strong>.<\/strong>\u00a0J Throm Haemost<\/em>\u00a02009; 7:1912-8<\/span><\/p>\n<p>Carri\u00e8re I., Fourrier-Reglat A., Dartigues J-F., Rouaud O., Pasquier F., Ritchie K. and Ancelin M.L.\u00a0<strong>Drugs with anticholinergic properties, cognitive decline and dementia in an elderly general population (The Three City Study).<\/strong>\u00a0<em>Arch Intern Med<\/em>\u00a02009; 169:1317-24<\/p>\n<p>Chapuis J, Hot D, Hansmannel F, Kerdraon O, Ferreira S, Hubans C, Maurage CA, Huot L, Bensemain F, Laumet G, Ayral AM, Fi\u00e9vet N, Hauw JJ, DeKosky ST, Lemoine Y, Iwatsubo T, Wavrabt-Devri\u00e8ze F, Dartigues JF, Tzourio C, Bu\u00e9e L, Pasquier F, Berr C, Mann D, Lendon C, Alp\u00e9rovitch A, Kamboh Mi, Amouyel P, Lambert JC.<strong>\u00a0Transcriptomic and genetic studies identify IL-33 as a candidate gene for Alzheimer\u2019s disease.<\/strong>\u00a0<em>Molecular Psychiatry<\/em>\u00a02009; 14:1004-16<\/p>\n<p>Debette S, Bevan S, Dartigues JF, Sitzer M, Lorenz M, Ducimeti\u00e8re P, Amouyel P, Markus HS.\u00a0<strong>Fractalkine receptor\/ligand genetic variants and carotid intima-media thickness.\u00a0<\/strong><em>Stroke<\/em>\u00a02009; 40:2212-4<\/p>\n<p>Dumurgier J, Elbaz A, Ducimeti\u00e8re P, Tavernier B, Alp\u00e9rovitch A, Tzourio C.\u00a0<strong>Slow walking speed and cardiovascular death in well functioning older adults: prospective cohort study.<\/strong>\u00a0<em>BMJ<\/em>\u00a02009; 339:<\/p>\n<p>Empana JP, Dauvilliers Y, Dartigues JF, Ritchie K, Gariepy J, Jouven X, Tzourio C, Amouyel P, Besset A, Ducimeti\u00e8re P.\u00a0<strong>Excessive daytime sleepiness is an independent risk factor for cardiovascular mortality in community-dwelling elderly.<\/strong>\u00a0<strong>The Three-City Study.<\/strong>\u00a0<em>Stroke<\/em>\u00a02009; 40:1219-1224<\/p>\n<p>F\u00e9art C, Samieri\u00a0 C, Rondeau V, Ami\u00e9va H, Portet F, Dartigues JF, Scarmeas N, Barberger-Gateau P.\u00a0<strong>Adherence to the Mediterranean Diet, Cognitive Decline and Risk of Dementia.<\/strong>\u00a0<em>JAMA<\/em>, 2009; 302:638-48<\/p>\n<p>Godin O, Maillard P, Crivello F, Alp\u00e9rovitch A, Mazoyer B, Tzourio C, Dufouil C.\u00a0<strong>Hippocampal atrophy, whole brain volumes and white matter lesions. The 3C-Dijon MRI study.<\/strong>\u00a0<em>Cerebrovasc Dis<\/em>\u00a02009; 28:2327-31<\/p>\n<p>Godin O, Tzourio C,\u00a0 Maillard P, Alp\u00e9rovitch A,\u00a0 Mazoyer B, Dufouil C.\u00a0\u00a0<strong>Apolipoprotein E genotype is related to progression of white matter lesions load.<\/strong>\u00a0<em>Stroke<\/em>\u00a02009; 40:3186-90<\/p>\n<p>Isaac V, Stewart R, Artero S, Ancelin M-L, Ritchie K.\u00a0<strong>Social activity and improvement in depressive symptoms in the elderly: a prospective community cohort study.<\/strong>\u00a0<em>Am\u00a0 J Geriatric Psychiatry\u00a0<\/em>2009; 17:688-696<\/p>\n<p>Lachouri M, Gourlet V, D&rsquo;Athis P, Tzourio C, Quantin C.\u00a0<strong>Changes in blood pressure in a large cohort of elderly individuals: Study 3C.<\/strong>\u00a0Arch Cardiovasc Dis. 2009;102(2):127-34. Epub 2009 Feb 12.<\/p>\n<p>Lambert JC, Schraen-Maschke S, Richard F, Fievet N, Rouaud O, Berr C, Dartigues J-F, Tzourio C, Alp\u00e9rovitch A, Bu\u00e9e L, Amouyel P.\u00a0<strong>Association of plasma A\u03b2 with risk of dementia : the prospective 3C-study.\u00a0<\/strong><em>Neurology<\/em>\u00a02009; 73:847-853<\/p>\n<p>Lambert JC, Heath S, Even G, Campion D, Sleegers K, Hiltunen M, Combarros O, Zelenika D, Bullido MJ, Tavernier B, Letenneur L, Bettens K, Berr C, Pasquier F, Fi\u00e9vet N, Barberger-Gateau P, Engelborghs S, De Deyn P, Mateo I, Franck A, Helisalmi S, Porcellini E, Hanon O; the European Alzheimer&rsquo;s Disease Initiative Investigators, de Pancorbo MM, Lendon C, Dufouil C, Jaillard C, Leveillard T, Alvarez V, Bosco P, Mancuso M, Panza F, Nacmias B, Boss\u00f9 P, Piccardi P, Annoni G, Seripa D, Galimberti D, Hannequin D, Licastro F, Soininen H, Ritchie K, Blanch\u00e9 H, Dartigues JF, Tzourio C, Gut I, Van Broeckhoven C, Alp\u00e9rovitch A, Lathrop M, Amouyel P.\u00a0<strong>Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer\u2019s disease.<\/strong>\u00a0<em>Nat Genet<\/em>. 2009;41:1094-1099<\/p>\n<p>Noize P., Bazin F., Dufouil C., Lechevallier-Michel N., Ancelin M.L, Dartigues J.F., Tzourio C., Moore N. and Fourrier-R\u00e9glat A.\u00a0<strong>Comparison of health insurance claims and patient interviews in assessing drug use: data from the Three-City Study.<\/strong>\u00a0<em>Pharmacoepidemiology and Drug Safety<\/em>, 2009; 18(4):310-9.<\/p>\n<p>Maillard P, Crivello F, Dufouil C, Tzourio-Mazoyer N, Tzourio C and Mazoyer B.\u00a0<strong>Longitudinal follow-up of individual white matter hyperintensities in a large cohort of healthy elderly .<\/strong>\u00a0<em>Neuroradiology<\/em>\u00a02009; 51:209-220<\/p>\n<p>Raffaitin C, Gin H, Empana JP, Helmer C, Berr C, Tzourio C, Portet F, Dartigues JF, Alperovitch A, Barberger-Gateau P.\u00a0<strong>Metabolic syndrome and risk for incident Alzheimer&rsquo;s disease and vascular dementia: the three-city study.<\/strong>\u00a0<em>Diabetes Care<\/em>. 2009: 32:169-74<\/p>\n<p>Ritchie K*, Jaussent I *, Stewart R, Dupuy AM, Courtet P, Ancelin ML, Malafosse A.\u00a0<strong>Adverse childhood environment and late-life depression.<\/strong>\u00a0<em>Journal of Clinical Psychiatry<\/em>\u00a02009; 70:1281-88<\/p>\n<p>Ryan J, Carri\u00e8re I, Scali J, Ritchie K, Ancelin ML.\u00a0<strong>Life-time estrogen exposure and cognitive functioning in later life.<\/strong>\u00a0<em>Psychoneuroendocrinology<\/em>, 2009; 34:287-298<\/p>\n<p>Ryan J, Carri\u00e8re I, Scali J, Dartigues JF, Tzourio C, Ritchie K, Ancelin ML.\u00a0<strong>Characteristics of hormone therapy and the association with cognitive function and dementia: the prospective Three City Study.<\/strong>\u00a0<em>Neurology<\/em>\u00a02009; 73:1729-37<\/p>\n<p>Scali J, Ryan J, Carri\u00e8re I, Ritchie K, Ancelin ML.<strong>\u00a0A prospective study of hormonal treatment and anxiety disorders in community-dwelling elderly women (the Esprit Study).<\/strong>\u00a0J Affect Disord. 2009 May;115(1-2):274-9. Epub 2008 Oct 11<\/p>\n<p>Soumar\u00e9 A, Elbaz A, Zhu Y, Maillard P, Crivello F, Tavernier B, Dufouil C, Mazoyer B, and Tzourio C.\u00a0<strong>White matter lesions volume and motor performances in the elderly.<\/strong>\u00a0<em>Ann Neurol<\/em>2009; 65: 706-15<\/p>\n<p>Soumar\u00e9 A, Tavernier B, Alp\u00e9rovitch A, Tzourio C, Elbaz.\u00a0<strong>A cross-sectional and longitudinal study of the relation between walking speed and cognitive function in community-dwelling elderly people.<\/strong>\u00a0Journal of Gerontology:\u00a0<em>Medical Sciences<\/em>\u00a02009; 64:1058-65<\/p>\n<\/div>\n<div class=\"spacer\"><\/div>\n<div class=\"cms_bloc cms_bloc_text\"><\/div>\n<\/div><\/div><\/div><\/div><\/div><style type=\"text\/css\">.fusion-accordian  #accordion-880-9 .panel-title a .fa-fusion-box{ color: #ffffff;}.fusion-accordian  #accordion-880-9 .panel-title a .fa-fusion-box:before{ font-size: 16px; width: 16px;}.fusion-accordian  #accordion-880-9 .panel-title a{font-size:24px;}.fusion-accordian  #accordion-880-9 .fa-fusion-box { background-color: #212934;border-color: #212934;}.fusion-accordian  #accordion-880-9 .panel-title a:hover, #accordion-880-9 .fusion-toggle-boxed-mode:hover .panel-title a { color: #65bc7b;}.fusion-accordian  #accordion-880-9 .panel-title .active .fa-fusion-box,.fusion-accordian  #accordion-880-9 .panel-title a:hover .fa-fusion-box { background-color: #65bc7b!important;border-color: #65bc7b!important;}<\/style><div class=\"accordian fusion-accordian\"><div class=\"panel-group\" id=\"accordion-880-9\"><div class=\"fusion-panel panel-default\"><div class=\"panel-heading\"><h4 class=\"panel-title toggle\"><a aria-expanded=\"false\" aria-controls=\"5ba7ae19282df0603\" role=\"button\" data-toggle=\"collapse\" data-parent=\"#accordion-880-9\" data-target=\"#5ba7ae19282df0603\" href=\"#5ba7ae19282df0603\"><span class=\"fusion-toggle-icon-wrapper\" aria-hidden=\"true\"><i class=\"fa-fusion-box\" aria-hidden=\"true\"><\/i><\/span><span class=\"fusion-toggle-heading\">2010<\/span><\/a><\/h4><\/div><div id=\"5ba7ae19282df0603\" class=\"panel-collapse collapse \"><div class=\"panel-body toggle-content fusion-clearfix\">\n<p>Akbaraly TN, Kivimaki M, Ancelin ML, Barberger-Gateau P, Mura T, Tzourio C, Touchon J, Ritchie K, Berr C.\u00a0<strong>Metabolic syndrome, its components, and mortality in the elderly.<\/strong>\u00a0<em>J Clin Endocrinol Metab<\/em>\u00a02010 Nov; 95(11):E327-32. Epub 2010 Sep 1.<\/p>\n<p>Ancelin ML, Carri\u00e8re I, Boulenger JP, Malafosse A, Stewart R, Cristol JP, Ritchie K, Chaudieu I, Dupuy AM.<strong>\u00a0Gender and genotype modulation of the association between lipid levels and depressive symptomatology in community-dwelling elderly (the ESPRIT study).<\/strong>\u00a0Biol Psychiatry. 2010 Jul 15;68(2):125-32. Epub 2010 May 26.<\/p>\n<p>Auriacombe S, Helmer C, Amieva H, Berr C, Dubois B, Dartigues JF.\u00a0<strong>Validity of the free and cued selective reminding test in predicting dementia: the 3C study.<\/strong>\u00a0<em>Neurology<\/em>\u00a02010; 74:1760-7.<\/p>\n<p>Beluche I, Carri\u00e8re I, Ritchie K Ancelin ML.\u00a0<strong>A prospective study of diurnal cortisol and cognitive function in community-dwelling elderly people.<\/strong>\u00a0<em>Psychological Medicin<\/em>e 2010; 40:1039-1049<\/p>\n<p><span class=\"title\">Bentayeb M, Helmer C, Raherison C, Dartigues JF, Tessier JF, Annesi-Maesano I.\u00a0<strong>Bronchitis-like symptoms and proximity air pollution in French elderly.<\/strong>\u00a0<em>Respir Med<\/em>\u00a02010; 104(6): 880-8. Epub 2010 Feb 2.PMID: 20129767<\/span><\/p>\n<p>Bonaventure A, Kurth T, Pico F, Barberger-Gateau P, Ritchie K, Stapf C, Tzourio C.\u00a0<strong>Serum triglycerides and the risk of hemorrhagic stroke vs. ischemic vascular events: the Three-City Study.<\/strong>\u00a0<em>Atherosclerosis<\/em>\u00a02010; 30:159-167<\/p>\n<p>Crivello F, Lema\u00eetre H, Dufouil C, Grassiot B, Delcroix N, Tzourio-Mazoyer N, Tzourio C, Mazoyer B.\u00a0<strong>Effects of ApoE-epsilon4 allele load and age on the rates of grey matter and hippocampal volumes loss in a longitudinal cohort of 1186 healthy elderly persons.<\/strong>\u00a0<em>Neuroimage<\/em>\u00a02010; 53(3): 1064-9.<\/p>\n<p>Debette S, Bis JC, Fornage M, Schmidt H, Ikram MA, Sigurdsson S, Heiss G, Struchalin M, Smith AV, van der Lugt A, DeCarli C, Lumley T, Knopman DS, Enzinger C, Eiriksdottir G, Koudstaal PJ, DeStefano AL, Psaty BM, Dufouil C, Catellier DJ, Fazekas F, Aspelund T, Aulchenko YS, Beiser A, Rotter JI, Tzourio C, Shibata DK, Tscherner M, Harris TB, Rivadeneira F, Atwood LD, Rice K, Gottesman RF, van Buchem MA, Uitterlinden AG, Kelly-Hayes M, Cushman M, Zhu Y, Boerwinkle E, Gudnason V, Hofman A, Romero JR, Lopez O, van Duijn CM, Au R, Heckbert SR, Wolf PA, Mosley TH, Seshadri S, Breteler MM, Schmidt R, Launer LJ, Longstreth WT Jr.\u00a0<strong>Genome-wide association studies of MRI-defined brain infarcts: meta-analysis<\/strong>\u00a0from the CHARGE Consortium.\u00a0<em>Stroke<\/em>\u00a02010; 41(2): 210-7<\/p>\n<p>Delcourt C, Korobelnik JF, Barberger-Gateau P, Delfyer MN, Rougier MB, Le Goff\u00a0 M, Malet F, Colin J, Dartigues JF.\u00a0<strong>Nutrition and age-related eye diseases\u00a0: the\u00a0 ALIENOR (antioxydants, lipides essentiels, nutrition et maladies oculaires) study.<\/strong>\u00a0<em>J Nutr Health Aging<\/em>\u00a02010\u00a0; 14\u00a0:854-61 (the ALIENOR study is conducted in a sub-group of the 3C-Bordeaux cohort.)<\/p>\n<p>Dumurgier J, Elbaz A, Dufouil C, Tavernier B, Tzourio C\u00a0<strong>Hypertension and lower walking speed in the elderly: the Three-City study.<\/strong><em>\u00a0J Hypertens<\/em>\u00a02010; 28(7):1506-14.<\/p>\n<p>F\u00e9art C, Siewe A, Samieri C, Peuchant E, Helmer C, Alfos S, Pallet V, Barberger-Gateau P.\u00a0<strong>Plasma retinol and association with socio-demographic and dietary characteristics of free-living older persons: the Bordeaux sample of the three-city study.<\/strong>\u00a0<em>Int J Vitam Nutr Res<\/em>\u00a02010; 80:32-44<\/p>\n<p>F\u00e9art C, Samieri C, Barberger-Gateau P.<strong>\u00a0Mediterranean diet and cognitive function in older adults. Curr Opin Clin Nutr Metab Care.<\/strong>\u00a02010 Jan;13(1):14-8.<\/p>\n<p>Godin O, Tzourio C, Rouaud O, Zhu Y, Maillard P, Pasquier F, Crivello F, Alp\u00e9rovitch A, Mazoyer B, Dufouil C.\u00a0<strong>Joint effect of white matter lesions and hippocampal volumes on severity of cognitive decline: the 3C-Dijon MRI study.<\/strong>\u00a0<em>J Alzheimers Dis<\/em>\u00a02010; 20(2):453-63.<\/p>\n<p><span class=\"title\">Lambert JC, Sleegers K, Gonz\u00e1lez-P\u00e9rez A, Ingelsson M, Beecham GW, Hiltunen M, Combarros O, Bullido MJ, Brouwers N, Bettens K, Berr C, Pasquier F, Richard F, Dekosky ST, Hannequin D, Haines JL, Tognoni G, Fi\u00e9vet N, Dartigues JF, Tzourio C, Engelborghs S, Arosio B, Coto E, De Deyn P, Del Zompo M, Mateo I, Boada M, Antunez C, Lopez-Arrieta J, Epelbaum J, Schjeide BM, Frank-Garcia A, Giedraitis V, Helisalmi S, Porcellini E, Pilotto A, Forti P, Ferri R, Delepine M, Zelenika D, Lathrop M, Scarpini E, Siciliano G, Solfrizzi V, Sorbi S, Spalletta G, Ravaglia G, Valdivieso F, Veps\u00e4l\u00e4inen S, Alvarez V, Bosco P, Mancuso M, Panza F, Nacmias B, Boss\u00f9 P, Hanon O, Piccardi P, Annoni G, Mann D, Marambaud P, Seripa D, Galimberti D, Tanzi RE, Bertram L, Lendon C, Lannfelt L, Licastro F, Campion D, Pericak-Vance MA, Soininen H, Van Broeckhoven C, Alp\u00e9rovitch A, Ruiz A, Kamboh MI, Amouyel P.\u00a0<strong>The CALHM1 P86L polymorphism is a genetic modifier of age at onset in Alzheimer&rsquo;s disease: a meta-analysis study.<\/strong>\u00a0<em>J Alzheimer\u2019s Dis<\/em>\u00a02010; 22(1): 247-55<\/span><\/p>\n<p><span class=\"title\">Lambert JC, Grenier-Boley B, Chouraki V, Heath S, Zelenika D, Fievet N, Hannequin D, Pasquier F, Hanon O, Brice A, Epelbaum J, Berr C, Dartigues JF, Tzourio C, Campion D, Lathrop M, Amouyel P.\u00a0<strong>Implication of the immune system in Alzheimer&rsquo;s disease: evidence from genome-wide pathway analysis.\u00a0<\/strong>\u00a0<em>J Alzheimers Dis<\/em>\u00a02010; 20(4):1107-18<\/span><\/p>\n<p>Le Fur I, Laumet G, Richard F, Fi\u00e9vet N, Berr C, Rouaud O, Delcourt C, Amouyel P, Lambert JC.\u00a0<strong>Association study of the CFH Y402H polymorphism with Alzheimer\u2019s disease.<\/strong>\u00a0Neurobiol Aging 2010; 31:165-66.<\/p>\n<p><span class=\"title\">Laumet G, Chouraki V, Grenier-Boley B, Legry V, Heath S, Zelenika D, Fievet N, Hannequin D, Delepine M, Pasquier F, Hanon O, Brice A, Epelbaum J, Berr C, Dartigues JF, Tzourio C, Campion D, Lathrop M, Bertram L, Amouyel P, Lambert JC.\u00a0<strong>Systematic analysis of candidate genes for Alzheimer&rsquo;s disease in a French, genome-wide association study.\u00a0<\/strong><em>J Alzheimers Dis<\/em>\u00a02010; 20(4): 1181-8<\/span><\/p>\n<p>Plichart M, Barberger-Gateau P, Tzourio C, Amouyel P, P\u00e9r\u00e8s K, Ritchie K, Jouven X, Ducimeti\u00e8re P, Empana JP.\u00a0<strong>Disability and incident coronary heart disease in older community-dwelling adults: the Three-City Study.<\/strong>\u00a0<em>J Am Geriatr Soc<\/em>2010; 58:636-42<\/p>\n<p>Power T, Stewart R, Ancelin ML, Jaussent I, Malafosse A, Ritchie K.\u00a0<strong>5-HTTLPR genotype, stressful life events and late-life depression: No evidence of interaction in a French population.<\/strong>\u00a0<em>Neurobiology of Aging\u00a0<\/em>2010<em>;31:886-887<\/em>;<\/p>\n<p>Ritchie K, Artero S, Portet F, Brickman AM, Muraskin J, Beanino E, Ancelin ML, Carri\u00e8re I.\u00a0<strong>Caffeine, cognitive functioning and white matter lesions in the elderly: establishing causality from epidemiological evidence.<\/strong>\u00a0<em>J Alzheimer\u2019s Disease\u00a0<\/em>2010; 20:S161-S166.<\/p>\n<p>Ritchie K* Carri\u00e8re I*, Ritchie C, Berr C, Artero S, Ancelin ML.\u00a0<strong>Can we design population prevention programs to reduce dementia incidence? Simulation of the impact of removal of specific risk factors.<\/strong>\u00a0<em>British Medical Journal\u00a0<\/em>2010, Aug 5;341:c3885. doi: 10.1136\/bmj.c3885.\u00a0<em>&amp; Author replyEpub Sep 3.<\/em><\/p>\n<p>Ritchie K, Ancelin ML, Beanino E, Portet., Brickman A, Dartigues JF, Tzourio C, Dupuy AM, Ritchie C, Berr C, Artero S.\u00a0<strong>Retrospective identification and characterization of Mild Cognitive Impairment from a prospective population cohort.<\/strong>\u00a0<em>Am J Geriatric Psychiatry\u00a0<\/em>2010<em>,<\/em>\u00a018:692-700.<\/p>\n<p><span class=\"title\">Scali J, Ryan J, Carri\u00e8re I, Dartigues JF, Tavernier B, Ritchie K, Ancelin ML.\u00a0<strong>A prospective study of hormone therapy and depression in community-dwelling elderly women: the three city study.<\/strong>\u00a0<em>J Clin Psychiatry<\/em>\u00a0\u00a02010; 71:1673-9<\/span><\/p>\n<p><span class=\"title\">Seshadri S, Fitzpatrick AL, Ikram MA, DeStefano AL, Gudnason V, Boada M, Bis JC, Smith AV, Carassquillo MM, Lambert JC, Harold D, Schrijvers EM, Ramirez-Lorca R, Debette S, Longstreth WT Jr, Janssens AC, Pankratz VS, Dartigues JF, Hollingworth P, Aspelund T, Hernandez I, Beiser A, Kuller LH, Koudstaal PJ, Dickson DW, Tzourio C, Abraham R, Antunez C, Du Y, Rotter JI, Aulchenko YS, Harris TB, Petersen RC, Berr C, Owen MJ, Lopez-Arrieta J, Varadarajan BN, Becker JT, Rivadeneira F, Nalls MA, Graff-Radford NR, Campion D, Auerbach S, Rice K, Hofman A, Jonsson PV, Schmidt H, Lathrop M, Mosley TH, Au R, Psaty BM, Uitterlinden AG, Farrer LA, Lumley T, Ruiz A, Williams J, Amouyel P, Younkin SG, Wolf PA, Launer LJ, Lopez OL, van Duijn CM, Breteler MM; CHARGE Consortium; GERAD1 Consortium; EADI1 Consortium.<strong>\u00a0Genome-wide analysis of genetic loci associated with Alzheimer disease.<\/strong>\u00a0<em>JAMA<\/em>\u00a02010; 303(18): 1832-40<\/span><\/p>\n<p>Soremekun M, Stewart R, Portet F, Artero S, Ancelin ML, Ritchie K.\u00a0<strong>Neurological signs and late-life depressive symptoms in a community population: the ESPRIT study.<\/strong>\u00a0Int J Geriatr Psychiatry. 2010 Jul;25(7):672-8.<\/p>\n<p>Straczek C, Ducimetiere P, Barberger-Gateau P, Helmer C, Ritchie K, Jouven X, Carcaillon L, Amouyel P, Tzourio C, Empana JP.\u00a0<strong>Higher level of systemic C-reactive protein is independently predictive of coronary heart disease in older community-dwelling adults: the three-city study.\u00a0<\/strong><em>J Am Geriatr Soc 2010<\/em>\u00a0; 58(1):129-35<\/p>\n<p>Zhu YC, Tzourio C, Soumar\u00e9 A, Mazoyer B, Dufouil C, Chabriat H.\u00a0<strong>Severity of dilated Virchow-Robin spaces is associated with age, blood pressure, and MRI markers of small vessel disease: a population-based study.<\/strong>\u00a0<em>Stroke<\/em>\u00a02010; 41(11): 2483-90.<\/p>\n<p>Zhu YC, Dufouil C, Soumar\u00e9 A, Mazoyer B, Chabriat H, Tzourio C.\u00a0<strong>High Degree of Dilated Virchow-Robin Spaces on MRI is Associated with Increased Risk of Dementia.\u00a0<\/strong><em>J Alzheimer\u2019s Dis 2010 Aug 30.<\/em>\u00a0<\/p>\n<\/div><\/div><\/div><\/div><\/div><style type=\"text\/css\">.fusion-accordian  #accordion-880-10 .panel-title a .fa-fusion-box{ color: #ffffff;}.fusion-accordian  #accordion-880-10 .panel-title a .fa-fusion-box:before{ font-size: 16px; width: 16px;}.fusion-accordian  #accordion-880-10 .panel-title a{font-size:24px;}.fusion-accordian  #accordion-880-10 .fa-fusion-box { background-color: #212934;border-color: #212934;}.fusion-accordian  #accordion-880-10 .panel-title a:hover, #accordion-880-10 .fusion-toggle-boxed-mode:hover .panel-title a { color: #65bc7b;}.fusion-accordian  #accordion-880-10 .panel-title .active .fa-fusion-box,.fusion-accordian  #accordion-880-10 .panel-title a:hover .fa-fusion-box { background-color: #65bc7b!important;border-color: #65bc7b!important;}<\/style><div class=\"accordian fusion-accordian\"><div class=\"panel-group\" id=\"accordion-880-10\"><div class=\"fusion-panel panel-default\"><div class=\"panel-heading\"><h4 class=\"panel-title toggle\"><a aria-expanded=\"false\" aria-controls=\"73659ea57c764069a\" role=\"button\" data-toggle=\"collapse\" data-parent=\"#accordion-880-10\" data-target=\"#73659ea57c764069a\" href=\"#73659ea57c764069a\"><span class=\"fusion-toggle-icon-wrapper\" aria-hidden=\"true\"><i class=\"fa-fusion-box\" aria-hidden=\"true\"><\/i><\/span><span class=\"fusion-toggle-heading\">2011<\/span><\/a><\/h4><\/div><div id=\"73659ea57c764069a\" class=\"panel-collapse collapse \"><div class=\"panel-body toggle-content fusion-clearfix\">\n<div class=\"cms_bloc cms_bloc_text\">\n<p>Akbaraly TN, Ancelin ML, Jaussent I, Ritchie K, Barberger-Gateau P, Dufouil C, Kivimaki M, Berr C, Ritchie K.\u00a0<strong>Metabolic syndrome and onset of depressive symptoms in the elderly.<\/strong>\u00a0<em>Diabetes Care<\/em>, 2011, 34(4):904-9.<\/p>\n<p>Allanore Y, Saad M, Philippe D, Avouac J, Distler JHW, Amouyel P, Matucci-Cerinic M, Riemekasten G, Airo P, Melchers I, Hachulla E, Daniele C, Hans-Erich W, Wipff J, Lambert J-C, Hunzelmann N, Tiev K, Caramaschi P, Diot E, Kowal-Bielecka O, Valentini G, Mouthon L, Laszlo C, Damjanov N, Salvi E, Conti C, Muller M, Muller-Ladner U, Riccieri O, Ruiz B, Cracowski J-L, Letenneur L, Dupuy A-M, Meyer O, Kahan A, Munnich A, Boileau C, Martinez M.\u00a0<strong>Genomewide scan identifies TNIP1, PSOR1C1 and RHOB as novel risk loci for systemic sclerosis.<\/strong><em>Plos Genet.<\/em>, 2011;7:e1002091.<\/p>\n<p>Ancelin ML*, Carri\u00e8re I*, Helmer C, Rouaud O, Pasquier F, Berr C, Chaudieu I, Ritchie K.\u00a0<strong>Steroid and nonsteroidal anti-inflammatory drugs, cognitive decline, and dementia.<\/strong>\u00a0\u00a0<em>Neurobiology of Aging,<\/em>\u00a02011, doi:10.1016\/j.neurobiolaging.2011.09.038.<\/p>\n<p><span class=\"Paragraphedeliste\">Artero S, Touchon J, Dupuy A-M, Malafosse A, RitchieK.\u00a0<strong>War exposure, 5-HTTPLPR genotype and life-time risk of depression.\u00a0<\/strong><em>British Journal of Psychiatry.\u00a0<\/em>2011; 199:43-8.<\/span><\/p>\n<p>Barberger-Gateau P, Samieri C, F\u00e9art C, Plourde M.\u00a0<strong>Dietary omega 3 polyunsaturated fatty acids and Alzheimer&rsquo;s disease: interaction with apolipoprotein E genotype.<\/strong>\u00a0Curr Alzheimer Res. 2011 Aug;8(5):479-91. Review<\/p>\n<p>Breton G, Froissart M, Janus N, Launay-Vacher V, Berr C, Tzourio C, Helmer C, Stengel B.\u00a0<strong>Inappropriate drug use and mortality in community-dwelling elderly with impaired kidney function- the Three-City population-based study.\u00a0<\/strong><em>Nephrol Dial Transplant.\u00a0<\/em>2011 Sep;26(9):2852-9.<\/p>\n<p>Cacciolati C, Hanon O, Alp\u00e9rovitch A, Dufouil C, Tzourio C.<strong>\u00a0Masked hypertension in the elderly: cross-sectional analysis of a population-based sample.<\/strong>\u00a0<em>Am J Hypertens.\u00a0<\/em>2011 Jun;24(6):674-80.<\/p>\n<p>Capuron, L., S. Schroecksnadel, C. F\u00e9art, A. Aubert, D. Higueret, P. Barberger-Gateau, S. Lay\u00e9 and D. Fuchs. 2011.<strong>Chronic low-grade inflammation in elderly persons Is associated with altered tryptophan and tyrosine metabolism: role in neuropsychiatric symptoms<\/strong>.\u00a0<em>Biological Psychiatry,<\/em>\u00a070, 175-82.<\/p>\n<p><span class=\"desc\">Carcaillon L, Alhenc-Gelas M, Bejot Y, Spaft C, Ducimeti\u00e8re P, Ritchie K, Dartigues JF, Scarabin PY.\u00a0<strong>Increased thrombin generation is associated with acute ischemic stroke but not with coronary heart disease in the elderly: the Three-City cohort study.\u00a0<\/strong><em>Arterioscler Thromb Vasc Biol<\/em><em>.<\/em> 2011;31:1445-51<\/span><\/p>\n<p>Carri\u00e8re I, Gutierrez LA, P\u00e9r\u00e8s K, Berr C, Barberger-Gateau P, Ritchie K, Ancelin ML.\u00a0<strong>Late life depression and incident activity limitations: influence of gender and symptom severity.\u00a0<\/strong><em>Journal of Affective Disorders<\/em>, 2011, 133:42-50.<\/p>\n<p>Chaudieu I, Norton J, Ritchie K, Birmes P, Vaiva G, Ancelin ML.<strong>\u00a0Long-term health consequences of exposure to trauma in general elderly population: The mediating role of reexperiencing posttraumatic symptoms.<\/strong>\u00a0<em>Journal of Clinical Psychiatry\u00a0<\/em>2011, 72(7):929-935.<\/p>\n<p><span class=\"Paragraphedeliste\">Cyprien F, Courtet P, Malafosse A, Maller J, Meslin C, Bonaf\u00e9 A, Le Bars E, Menjot de Champfleur N<sup>\u00a0<\/sup>, Ritchie K, Artero S.\u00a0<strong>Suicidal behavior is associated with reduced corpus callosum area.<\/strong><em>Biological Psychiatry.\u00a0<\/em>2011; 70:320-326.<\/span><\/p>\n<p>Danaei G, Finucane MM, Lin JK, Singh GM, Paciorek CJ, Cowan MJ, Farzadfar F, Stevens GA, Lim SS, Riley LM, Ezzati M;\u00a0<strong>Global Burden of Metabolic Risk Factors of Chronic Diseases Collaborating Group (Blood Pressure). National, regional, and global trends in systolic blood pressure since 1980: systematic analysis of health examination surveys and epidemiological studies with 786 country-years and 5\u00b74 million participants.\u00a0<\/strong><em>Lancet.\u00a0<\/em>2011 Feb 12;377(9765):568-77.<\/p>\n<p>Delcourt C, Delyfer MN, Rougier MB, Amouyel P, Colin J, Le Goff M, Malet F, Dartigues JF, Lambert JC, Korobelnik JF.<strong>\u00a0Associations of Complement Factor H and smoking with early age-related macular degeneration: the Alienor Study.<\/strong>\u00a0<em>IOVS<\/em>\u00a02011; 52: 5955-62. (the ALIENOR study is conducted in a sub-group of the 3C-Bordeaux cohort.)<\/p>\n<p><span class=\"title\">Empana J, Tafflet M, Escolano S, Vergnaux A, Bineau S, Ruidavets J, Montaye M, Haas B, Czernichow S, Balkau B, Ducimetiere P.\u00a0<strong>Predicting CHD risk in France: a pooled analysis of the D.E.S.I.R., Three City, PRIME, and SU.VI.MAX studies.\u00a0<\/strong><em>Eur J Cardiovasc Prev Rehabil<\/em>. 2011;18:175-8<\/span><\/p>\n<p>Feart, C., M.J. Torres, C. Samieri, M.A. Jutand, E. Peuchant, A.P. Simopoulos and P. Barberger Gateau. 2011.<strong>\u00a0Adherence to a Mediterranean Diet and plasma fatty acids: data from the Bordeaux sample of the Three-City study<\/strong>.<em>\u00a0Brit J Nutr<\/em>, 106 (1), 149-58.<\/p>\n<p>Feart C, Helmer C, Fleury H, B\u00e9jot Y, Ritchie K, Amouyel P, Schraen-Maschke S, Bu\u00e9e L, Lambert JC, Letenneur L, Dartigues JF. <strong>Association between IgM anti-herpes simplex virus and plasma amyloid-beta levels.<\/strong>\u00a0PLoS One. 2011;6(12):e29480. Epub 2011 Dec 28<\/p>\n<p>Feart, C., K. P\u00e9r\u00e8s, C. Samieri, L. Letenneur, J.-F. Dartigues and P. Barberger-Gateau. 2011.<strong>\u00a0Adherence to a Mediterranean diet and onset of disability in older persons<\/strong>.\u00a0<em>European Journal of Epidemiology<\/em>, e pub, 1-10<\/p>\n<p>Fornage M, Debette S, Bis JC, Schmidt H, Ikram MA, Dufouil C, Sigurdsson S,<\/p>\n<p>Lumley T, DeStefano AL, Fazekas F, Vrooman HA, Shibata DK, Maillard P, Zijdenbos A, Smith AV, Gudnason H, de Boer R, Cushman M, Mazoyer B, Heiss G, Vernooij MW,Enzinger C, Glazer NL, Beiser A, Knopman DS, Cavalieri M, Niessen WJ, Harris TB, Petrovic K, Lopez OL, Au R, Lambert JC, Hofman A, Gottesman RF, Garcia M,Heckbert SR, Atwood LD, Catellier DJ, Uitterlinden AG, Yang Q, Smith NL, AspelundT, Romero JR, Rice K, Taylor KD, Nalls MA, Rotter JI, Sharrett R, van Duijn CM,Amouyel P, Wolf PA, Gudnason V, van der Lugt A, Boerwinkle E, Psaty BM, Seshadri S, Tzourio C, Breteler MM, Mosley TH, Schmidt R, Longstreth WT, DeCarli C, Launer LJ.\u00a0<strong>Genome-wide association studies of cerebral white matter lesion burden: the CHARGE consortium.<\/strong>\u00a0<em>Ann Neurol<\/em>. 2011 Jun;69(6):928-39.<\/p>\n<p>Genin E, Hannequin D, Wallon D, Sleegers K, Hiltunen M, Combarros O, Bullido MJ, Engelborghs S, De Deyn P, Berr C, Pasquier F, Dubois B, Tognoni G, Fievet N, Brouwers N, Bettens K, Arosio B, Coto E, Del Zompo M, Mateo I, Epelbaum J, Franck-Garcia A, Helisalmi S, Porcellini E, Pilotto A, Forti P, Ferri R, Scarpini E, Siciliano G, Solfrizzi V, Sorbi \u00a0S, Spalletta G, Valdivesio F, Vepsalainen S, Alvarez V, Bosco P, Mancuso M, Panza F, Nacmias B, Bossu P, Hanon O, Piccardi P, Annoni G, Seripa D, Galimberti D, Licastro F, Soininen H, Dartigues J-F, Kamboh MI, Van Broeckhoven C, Lambert J-C, Amouyel P, Campion D.\u00a0<strong>APOE and Alzheimer\u2019s disease : a major gene with semi-dominant inheritance.\u00a0<\/strong><em>Mol Psychiatry<\/em>, 2011;16:903-7.<\/p>\n<p>Germain M, Saut N, Greliche N, Dina C, Lambert JC, Perret C, Cohen W, Oudot-Mellakh T, Antoni G, Alessi MC, Zelenika D, Cambien F, Tiret L, Bertrand M, Dupuy AM, Letenneur L, Lathrop M, Emmerich J, Amouyel P, Tr\u00e9gou\u00ebt DA, Morange PE.\u00a0<strong>Genetics of venous thrombosis: insights from a new genome wide association study.\u00a0<\/strong><em>PLoS One<\/em>. 2011;6(9):e25581.<\/p>\n<p>Godin O, Tzourio C, Maillard P, Mazoyer B, Dufouil C.\u00a0<strong>Antihypertensive treatment and change in blood pressure are associated with the progression of white matter lesion volumes: the Three-City (3C)-Dijon Magnetic Resonance Imaging Study.<\/strong><em>\u00a0Circulation.\u00a0<\/em>2011 Jan 25;123(3):266-73.<\/p>\n<p>Grimaud O, Dufouil C, Alp\u00e9rovitch A, Pico F, Ritchie K, Helmer C, Tzourio C, Chauvin P.<strong>\u00a0Incidence of ischaemic stroke according to income level among older people: the 3C study.<\/strong>\u00a0<em>Age Ageing.<\/em>\u00a02011 Jan;40(1):116-21.<\/p>\n<p>Helmer C, Stengel B, Metzger M , Froissart M, Massy ZA, Tzourio C, Berr C, Dartigues JF.\u00a0<strong>Chronic Kidney Disease, cognitive decline and incident dementia: the 3C study.\u00a0\u00a0<\/strong><em>Neurology\u00a0<\/em>2011; 77(23):2043-2051,<\/p>\n<p>Hollingworth P, Harold D, Sims R, Gerrish A, Lambert JC, Carrasquillo MM, Abraham R, Hamshere ML, Pahwa JS, Moskvina V, Dowzell K, Jones N, Stretton A, Thomas C, Richards A, Ivanov D, Widdowson C, Chapman J, Lovestone S, Powell J, Proitsi P, Lupton MK, Brayne C, Rubinsztein DC, Gill M, Lawlor B, Lynch A, Brown KS, Passmore PA, Craig D, McGuinness B, Todd S, Holmes C, Mann D, Smith AD, Beaumont H, Warden D, Wilcock G, Love S, Kehoe PG, Hooper NM, Vardy ER, Hardy J, Mead S, Fox NC, Rossor M, Collinge J, Maier W, Jessen F, R\u00fcther E, Sch\u00fcrmann B,Heun R, K\u00f6lsch H, van den Bussche H, Heuser I, Kornhuber J, Wiltfang J, Dichgans M, Fr\u00f6lich L, Hampel H, Gallacher J, H\u00fcll M, Rujescu D, Giegling I, Goate AM,Kauwe JS, Cruchaga C, Nowotny P, Morris JC, Mayo K, Sleegers K, Bettens K,Engelborghs S, De Deyn PP, Van Broeckhoven C, Livingston G, Bass NJ, Gurling H,McQuillin A, Gwilliam R, Deloukas P, Al-Chalabi A, Shaw CE, Tsolaki M, Singleton AB, Guerreiro R, M\u00fchleisen TW, N\u00f6then MM, Moebus S, J\u00f6ckel KH, Klopp N, Wichmann HE, Pankratz VS, Sando SB, Aasly JO, Barcikowska M, Wszolek ZK, Dickson DW,Graff-Radford NR, Petersen RC; Alzheimer&rsquo;s Disease Neuroimaging Initiative, vanDuijn CM, Breteler MM, Ikram MA, DeStefano AL, Fitzpatrick AL, Lopez O, LaunerLJ, Seshadri S; CHARGE consortium, Berr C, Campion D, Epelbaum J, Dartigues JF,Tzourio C, Alp\u00e9rovitch A, Lathrop M; EADI1 consortium, Feulner TM, Friedrich P,Riehle C, Krawczak M, Schreiber S, Mayhaus M, Nicolhaus S, Wagenpfeil S,Steinberg S, Stefansson H, Stefansson K, Snaedal J, Bj\u00f6rnsson S, Jonsson PV,Chouraki V, Genier-Boley B, Hiltunen M, Soininen H, Combarros O, Zelenika D,Delepine M, Bullido MJ, Pasquier F, Mateo I, Frank-Garcia A, Porcellini E, Hanon O, Coto E, Alvarez V, Bosco P, Siciliano G, Mancuso M, Panza F, Solfrizzi V,Nacmias B, Sorbi S, Boss\u00f9 P, Piccardi P, Arosio B, Annoni G, Seripa D, Pilotto A,Scarpini E, Galimberti D, Brice A, Hannequin D, Licastro F, Jones L, Holmans PA, Jonsson T, Riemenschneider M, Morgan K, Younkin SG, Owen MJ, O&rsquo;Donovan M, Amouyel, P, Williams J.\u00a0<strong>Common variants at ABCA7, MS4A6A\/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer&rsquo;s disease.<\/strong>\u00a0<em>Nat Genet.<\/em>\u00a02011 May;43(5):429-35.<\/p>\n<p>Hong MG, Alexeyenko A, Lambert JC, Amouyel P, Prince JA.\u00a0<strong>Genome-wide pathway analysis implicates intracellular transmembrane protein transport in Alzheimer disease.\u00a0<\/strong><em>J Hum Genet.<\/em>, 2010;55:707-9.<\/p>\n<p><span class=\"title\">Jaussent I, Dauvilliers Y, Ancelin ML, Dartigues JF, Tavernier B, Touchon J, Ritchie K, Besset A.\u00a0<strong>Insomnia Symptoms in Older Adults: Associated Factors and Gender Differences.\u00a0<\/strong><em>Am J Geriatr Psychiatry<\/em> 2011; 19:88-9<\/span><\/p>\n<p>Jaussent I, Bouyer J, Ancelin ML, AkbaralyTN, P\u00e9r\u00e8s K, Ritchie K, Besset A, Dauvilliers Y.\u00a0<strong>Insomnia and daytime sleepiness are risk factors for depressive symptoms in the elderly.\u00a0<\/strong><em>Sleep<\/em>, 2011, 34(8):1103-10.<\/p>\n<p>Lambert JC, Dallongeville J, Ellis KA, Schraen-Maschke S, Lui J, Laws S, Dumont J, Richard F, Cottel D, Berr C, Ames D, Masters CL, Rowe CC, Szoeke C, Tzourio C, Dartigues JF, Bu\u00e9e L, Martins R, Amouyel P.\u00a0<strong>Association of plasma A\u00df peptides with blood pressure in the elderly.<\/strong>\u00a0<em>PLoS One<\/em>. 2011 Apr 15;6(4):e18536.<\/p>\n<p>Legeai C, Jouven X, Tafflet M, Dartigues J, Helmer C, Ritchie K, Amouyel P, Tzourio C, Ducimeti\u00e8re P, Empana J<strong>. Resting heart rate, mortality and future coronary heart disease in the elderly: the 3C study.\u00a0<\/strong><em>Eur J Cardiovasc Prev Rehabil.<\/em>\u00a02011 Jun;18(3):488-97.<\/p>\n<p>Lenoir H, Dufouil C, Auriacombe S, Lacombe JM, Dartigues JF, Ritchie K, Tzourio C.\u00a0<strong>Depression history, depressive symptoms, and incident dementia: the 3C Study.\u00a0<\/strong><em>J Alzheimers Dis<\/em>. 2011;26(1):27-38.<\/p>\n<p>Leone N, Courbon D, Berr C, Barberger-Gateau P, Tzourio C, Alp\u00e9rovitch A, Zureik M.\u00a0<strong>Abdominal obesity and late-onset asthma: cross-sectional and longitudinal results: the 3C Study.\u00a0<\/strong><em>Obesity<\/em>\u00a02011 Oct 20. doi: 10.1038\/oby.2011.308. [Epub ahead of print]\n<p>Merle B, Delyfer MN, Korobelnik JF, Rougier MB, Colin J, Malet F, F\u00e9art C, Le Goff M, Dartigues JF, Barberger-Gateau P, Delcourt C.\u00a0<strong>Dietary omega 3 fatty acids and the risk for age-related maculopathy: the Alienor Study.\u00a0<\/strong><em>IOVS<\/em>\u00a02011; 52: 6004-11. (the ALIENOR study is conducted in a sub-group of the 3C-Bordeaux cohort.)<\/p>\n<p>Montlahuc C, Soumar\u00e9 A, Dufouil C, Berr C, Dartigues JF, Poncet M, Tzourio C, Alp\u00e9rovitch A.\u00a0<strong>Self-rated health and risk of incident dementia: a community-based elderly cohort, the 3C study.<\/strong>\u00a0<em>Neurology<\/em>\u00a02011;77(15):1457-64.<\/p>\n<p>Morange PE, Oudot-Mellakh T, Germain M, Saut n, Antoni G, Alessi MC, Bertrand M, Dupuy AM, Letenneur L, Lathrop M, Lopez LM, Lambert JC, Emmerich J, Amouyel P, Tregouet D.\u00a0<strong>KNG1 Ile581Thr and susceptibility to venous thrombosis.\u00a0<\/strong><em>Blood<\/em>, 2011;117:3692-4.<\/p>\n<p>Nalls MA, Plagnol V, Hernandez DG, Sharma M, Sheerin UM, Saad M, Sim\u00f3n-S\u00e1nchez J, Schulte C, Lesage S, Sveinbj\u00f6rnsd\u00f3ttir S, Arepalli S, Barker R, Ben-Shlomo Y, Berendse HW, Berg D, Bhatia K, de Bie RM, Biffi A, Bloem B, Bochdanovits Z, Bonin M, Bras JM, Brockmann K, Brooks J, Burn DJ, Charlesworth G, Chen H, Chinnery PF, Chong S, Clarke CE, Cookson MR, Cooper M, Corvol JC, Counsell C, Damier P, Dartigues JF, Deloukas P, Deuschl G, Dexter DT, van Dijk KD, Dillman A, Durif F, D\u00fcrr A, Edkins S, Evans JR, Foltynie T, Gao J, Gardner M, Gibbs JR, Goate A, Gray E, Guerreiro R, G\u00fastafsson \u00d3, Harris C, van Hilten JJ, Hofman A, Hollenbeck A, Hu M, Huang X, Huber H, Hudson G, Hunt SE, Huttenlocher J, Illig T, J\u00f3nsson PV, Lambert JC, Langford C, Lees A, Lichtner P, Limousin P, Lopez G, Lorenz D, McNeill A, Moorby C, Moore M, Morris HR, Morrison KE, Mudanohwo E, O&rsquo;Sullivan S, Pearson J, Perlmutter JS, P\u00e9tursson H, Pollak P, Post B, Potter S, Ravina B, Revesz T, Riess O, Rivadeneira F, Rizzu P, Ryten M, Sawcer S, Schapira A, Scheffer H, Shaw K, Shoulson I, Sidransky E, Smith C, Spencer CC, Stef\u00e1nsson H, Steinberg S, Stockton JD, Strange A, Talbot K, Tanner CM, Tashakkori-Ghanbaria A, Tison F, Trabzuni D, Traynor BJ, Utterlinden AG, Velseboer D, Vidailhet M, Walker R, van de Warrenburg B, Wickremaratchi M, Williams N, Williams-Gray CH, Winder-Rhodes S, Stef\u00e1nsson K, Martinez M, Hardy J, Heutink P, Brice A, Gasser T, Singleton AB, Wood NW.\u00a0<strong>Imputation of sequence variants for identification of genetic risks for Parkinson&rsquo;s disease: a meta-analysis of genome-wide association studies.\u00a0<\/strong><em>Lancet<\/em>, 2011, 19;377:641-9.<\/p>\n<p>Plagnol V, Nalls MA, Bras JM, Hernandez DG, Sharma M, Sheerin UM, Saad M, Sim\u00f3n-S\u00e1nchez J, Schulte C, Lesage S, Sveinbj\u00f6rnsd\u00f3ttir S, Amouyel P, Arepalli S, Band G, Barker RA, Bellinguez C, Ben-Shlomo Y, Berendse HW, Berg D, Bhatia K, de Bie RM, Biffi A, Bloem B, Bochdanovits Z, Bonin M, Brockmann K, Brooks J, Burn DJ, Charlesworth G, Chen H, Chinnery PF, Chong S, Clarke CE, Cookson MR, Cooper JM, Corvol JC, Counsell C, Damier P, Dartigues JF, Deloukas P, Deuschl G, Dexter DT, van Dijk KD, Dillman A, Durif F, D\u00fcrr A, Edkins S, Evans JR, Foltynie T, Freeman C, Gao J, Gardner M, Gibbs JR, Goate A, Gray E, Guerreiro R, G\u00fastafsson \u00d3, Harris C, Hellenthal G, van Hilten JJ, Hofman A, Hollenbeck A, Holton J, Hu M, Huang X, Huber H, Hudson G, Hunt SE, Huttenlocher J, Illig T, J\u00f3nsson PV, Langford C, Lees A, Lichtner P, Limousin P, Lopez G, Lorenz D, McNeill A, Moorby C, Moore M, Morris H, Morrison KE, Mudanohwo E, O&rsquo;Sullivan SS, Pearson J, Pearson R, Perlmutter JS, P\u00e9tursson H, Pirinen M, Pollak P, Post B, Potter S, Ravina B, Revesz T, Riess O, Rivadeneira F, Rizzu P, Ryten M, Sawcer S, Schapira A, Scheffer H, Shaw K, Shoulson I, Sidransky E, de Silva R, Smith C, Spencer CC, Stef\u00e1nsson H, Steinberg S, Stockton JD, Strange A, Su Z, Talbot K, Tanner CM, Tashakkori-Ghanbaria A, Tison F, Trabzuni D, Traynor BJ, Uitterlinden AG, Vandrovcova J, Velseboer D, Vidailhet M, Vukcevic D, Walker R, van de Warrenburg B, Weale ME, Wickremaratchi M, Williams N, Williams-Gray CH, Winder-Rhodes S, Stef\u00e1nsson K, Martinez M, Donnelly P, Singleton AB, Hardy J, Heutink P, Brice A, Gasser T, Wood NW.\u00a0<strong>International Parkinson&rsquo;s Disease Genomics Consortium (IPDGC); Wellcome Trust Case Control Consortium 2 (WTCCC2). A two-stage meta-analysis identifies several new loci for Parkinson&rsquo;s disease.<\/strong>\u00a0PLoS Genet. 2011 Jun;7(6):e1002142. Epub 2011 Jun 30.<\/p>\n<p>Plichart M, Celermajer DS, Zureik M, Helmer C, Jouven X, Ritchie K, Tzourio C, Ducimeti\u00e8re P, Empana JP.<strong>\u00a0Carotid intima-media thickness in plaque-free site, carotid plaques and coronary heart disease risk prediction in older adults. The Three-City Study.\u00a0<\/strong><em>Atherosclerosis<\/em>\u00a02011; 219:917-24<\/p>\n<p>Raffaitin C, F\u00e9art C, Le Goff M, Amieva H, Helmer C, Akbaraly TN, Tzourio C, Gin H, Barberger-Gateau P.<strong>\u00a0Metabolic syndrome and cognitive decline in French elders: the Three-City Study.<\/strong>\u00a0<em>Neurology<\/em>. 2011 Feb 8;76(6):518-25.<\/p>\n<p>Ritchie K, Jaussent I, Stewart R, Dupuy AM, Courtet P, Malafosse A, Ancelin ML.\u00a0<strong>Adverse childhood environment and late-life cognitive functioning.<\/strong>\u00a0Int J Geriatr\u00a0<em>Psychiatry<\/em>\u00a02011; 26:503-510.<\/p>\n<p>Ryan J, Scali J, Carri\u00e8re I, Dartigues JF, Tzourio C, Scarabin PY, Ritchie K, Ancelin ML.<strong>Oestrogen receptor polymorphisms and late-life depression.<\/strong><em>British Journal of Psychiatry<\/em>, 2011, 199:126-31.<\/p>\n<p><span class=\"details\">Ryan J, Scali J, Carri\u00e8re I, Scarabin PY, Ritchie K, Ancelin ML.\u00a0<strong>Estrogen receptor gene variants are associated with anxiety disorders in older women.\u00a0<\/strong><em>Psychoneuroendocrinology<\/em><em>.<\/em>\u00a02011 Nov;36(10):1582-6.<\/span><\/p>\n<p>Saad M, Lesage S, Saint-Pierre A, Corvol JC, Zelenika D, Lambert JC, Vidailhet M, Mellick GD, Lohmann E, Durif F, Pollak P, Damier P, Tison F, Silburn PA, Tzourio C, Forlani S, Loriot AM, Giroud M, Helmer C, Portet F, Amouyel P, Lathrop M, Elbaz A, Durr A, Martinez M, Brice A.\u00a0<strong>Genome-wide association study confirms BST1 and suggest a locus on 12q24 as risk loci for Parkinson\u2019s disease in the European population.<\/strong>\u00a0<em>Hum Mol Genet<\/em>, 2011;20:615-27.<\/p>\n<p>Samieri C, F\u00e9art C, Proust-Lima C, Peuchant E, Tzourio C, Stapf C, Berr C, Barberger-Gateau P.\u00a0<strong>Olive oil consumption, plasma oleic acid, and stroke incidence: the Three-City Study.<\/strong><em>Neurology.<\/em>\u00a02011;77(5):418-25.<\/p>\n<p>Samieri, C., C. Feart, C. Proust-Lima, E. Peuchant, J. Dartigues, H. Amieva and P. Barberger-Gateau. 2011.<strong>\u00a0Omega-3 fatty acids and cognitive decline: modulation by ApoEepsilon4 allele and depression.<\/strong><em>\u00a0Neurobiology of Aging<\/em>, 32 (12), 2317.e13-22.<\/p>\n<p>Stengel B, Metzger M, Froissart M, Rainfray M, Berr C, Tzourio C, Helmer C.\u00a0<strong>Epidemiology and prognostic significance of chronic kidney disease in the elderly- the Three-City prospective cohort study.\u00a0<\/strong><em>Nephrol Dial Transplant.<\/em>\u00a02011 Oct;26(10):3286-95.<\/p>\n<p>Stewart R, Godin O, Crivello F, Maillard P, Mazoyer B, Tzourio C, Dufouil C.\u00a0<strong>Longitudinal neuroimaging correlates of subjective memory impairment: 4-year prospective community study.<\/strong>\u00a0<em>Br J Psychiatry\u00a0<\/em>2011;198(3):199-205.<\/p>\n<p>Straczek C, M. Tafflet, P. Barberger-Gateau, M Bertrand, A.M.Dupuy, P. Ducimeti\u00e8re, JP. Empana.\u00a0<strong>Do lipids and apolipoproteins predict coronary heart disease under statin and fibrate therapy in the primary prevention setting in community-dwelling elderly subjects? The 3C Study.<\/strong>\u00a0<em>Atherosclerosis<\/em>\u00a02011; 214:426-31.<\/p>\n<p>Zhu YC, Dufouil C, Mazoyer B, Soumar\u00e9 A, Ricolfi F, Tzourio C, Chabriat H.\u00a0<strong>Frequency and location of dilated Virchow-Robin spaces in elderly people: a population-based 3D MR imaging study.<\/strong><em>\u00a0Am J Neuroradiol<\/em>. 2011; 32(4):709-13.<\/p>\n<\/div>\n<\/div><\/div><\/div><\/div><\/div><style type=\"text\/css\">.fusion-accordian  #accordion-880-11 .panel-title a .fa-fusion-box{ color: #ffffff;}.fusion-accordian  #accordion-880-11 .panel-title a .fa-fusion-box:before{ font-size: 16px; width: 16px;}.fusion-accordian  #accordion-880-11 .panel-title a{font-size:24px;}.fusion-accordian  #accordion-880-11 .fa-fusion-box { background-color: #212934;border-color: #212934;}.fusion-accordian  #accordion-880-11 .panel-title a:hover, #accordion-880-11 .fusion-toggle-boxed-mode:hover .panel-title a { color: #65bc7b;}.fusion-accordian  #accordion-880-11 .panel-title .active .fa-fusion-box,.fusion-accordian  #accordion-880-11 .panel-title a:hover .fa-fusion-box { background-color: #65bc7b!important;border-color: #65bc7b!important;}<\/style><div class=\"accordian fusion-accordian\"><div class=\"panel-group\" id=\"accordion-880-11\"><div class=\"fusion-panel panel-default\"><div class=\"panel-heading\"><h4 class=\"panel-title toggle\"><a aria-expanded=\"false\" aria-controls=\"bcf4b927d848d5be5\" role=\"button\" data-toggle=\"collapse\" data-parent=\"#accordion-880-11\" data-target=\"#bcf4b927d848d5be5\" href=\"#bcf4b927d848d5be5\"><span class=\"fusion-toggle-icon-wrapper\" aria-hidden=\"true\"><i class=\"fa-fusion-box\" aria-hidden=\"true\"><\/i><\/span><span class=\"fusion-toggle-heading\">2012<\/span><\/a><\/h4><\/div><div id=\"bcf4b927d848d5be5\" class=\"panel-collapse collapse \"><div class=\"panel-body toggle-content fusion-clearfix\">\n<p>Avila-Funes JA, Carcaillon L, Helmer C, Carri\u00e8re I, Ritchie K, Rouaud O, Tzourio C, Dartigues JF, Amieva H.<strong>\u00a0Is frailty a prodromal stage of vascular dementia? Results from the three-city study.<\/strong>\u00a0J Am Geriatr Soc. 2012 Sep;60(9):1708-12<\/p>\n<p>Ancelin ML, Carri\u00e8re I, Barberger-Gateau P, Auriacombe S, Rouaud O, Fourlanos S, Berr C, Dupuy AM, Ritchie K.\u00a0<strong>Lipid lowering agents, cognitive decline, and dementia: the three-city study.<\/strong>\u00a0J Alzheimers Dis. 2012;30(3):629-37.<\/p>\n<p>Ancelin ML, Carri\u00e8re I, Helmer C, Rouaud O, Pasquier F, Berr C, Chaudieu I, Ritchie K.\u00a0<strong>Steroid and nonsteroidal anti-inflammatory drugs, cognitive decline, and dementia.<\/strong>\u00a0Neurobiol Aging. 2012;33(9):2082-90. Epub 2011 Nov 8.<\/p>\n<p>Bazin F, Noize P, Dartigues JF, Ritchie KA, Tavernier B, Moore N, Pariente A, Fourrier-Reglat A.\u00a0<strong>Engagement in leisure activities and benzodiazepine use in a French community-dwelling elderly population.<\/strong>\u00a0Int J Geriatr Psychiatry. 2012;27(7):716-721. Epub 2011 Aug 31<\/p>\n<p>Bergua V, Meillon C, Potvin O, Bouisson J, Le Goff M, Rouaud O, Ritchie K, Dartigues JF, Amieva H.\u00a0<strong>The STAI-Y trait scale: psychometric properties and normative data from a large population-based study of elderly people.<\/strong>\u00a0Int Psychogeriatr. 2012 Jul;24(7):1163-71. Epub 2012 Mar 21.<\/p>\n<p>Bis JC, DeCarli C, Smith AV, van der Lijn F, Crivello F, Fornage M, Debette S, Shulman JM, Schmidt H, Srikanth V, Schuur M, Yu L, Choi SH, Sigurdsson S, Verhaaren BF, DeStefano AL, Lambert JC, Jack CR Jr, Struchalin M, Stankovich J, Ibrahim-Verbaas CA, Fleischman D, Zijdenbos A, den Heijer T, Mazoyer B, Coker LH, Enzinger C, Danoy P, Amin N, Arfanakis K, van Buchem MA, de Bruijn RF, Beiser A, Dufouil C, Huang J, Cavalieri M, Thomson R, Niessen WJ, Chibnik LB, Gislason GK, Hofman A, Pikula A, Amouyel P, Freeman KB, Phan TG, Oostra BA, Stein JL, Medland SE, Vasquez AA, Hibar DP, Wright MJ, Franke B, Martin NG, Thompson PM; Enhancing Neuro Imaging Genetics through Meta-Analysis Consortium, Nalls MA, Uitterlinden AG, Au R, Elbaz A, Beare RJ, van Swieten JC, Lopez OL, Harris TB, Chouraki V, Breteler MM, De Jager PL, Becker JT, Vernooij MW, Knopman D, Fazekas F, Wolf PA, van der Lugt A, Gudnason V, Longstreth WT Jr, Brown MA, Bennett DA, van Duijn CM, Mosley TH, Schmidt R, Tzourio C, Launer LJ, Ikram MA, Seshadri S;\u00a0<strong>Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium. 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Epub 2012 Aug 16<\/p>\n<p>Canonico M, Brailly-Tabard S, Gaussem P, Setiao J, Rouaud O, Ryan J, Carcaillon L, Guiochon-Mantel A, Scarabin PY.<strong>\u00a0Endogenous oestradiol as a positive correlate of plasma fibrinogen among older postmenopausal women: a population-based study (the Three-City cohort study).<\/strong>\u00a0Clin Endocrinol (Oxf). 2012;77(6):905-10<\/p>\n<p>Chasman DI, Fuchsberger C, Pattaro C, Teumer A, B\u00f6ger CA, Endlich K, Olden M, Chen MH, Tin A, Taliun D, Li M, Gao X, Gorski M, Yang Q, Hundertmark C, Foster MC, O&rsquo;Seaghdha CM, Glazer N, Isaacs A, Liu CT, Smith AV, O&rsquo;Connell JR, Struchalin M, Tanaka T, Li G, Johnson AD, Gierman HJ, Feitosa MF, Hwang SJ, Atkinson EJ, Lohman K, Cornelis MC, Johansson A, T\u00f6njes A, Dehghan A, Lambert JC, Holliday EG, Sorice R, Kutalik Z, Lehtim\u00e4ki T, Esko T, Deshmukh H, Ulivi S, Chu AY, Murgia F, Trompet S, Imboden M, Coassin S, Pistis G; CARDIoGRAM Consortium; ICBP Consortium; CARe Consortium; WTCCC2, Harris TB, Launer LJ, Aspelund T, Eiriksdottir G, Mitchell BD, Boerwinkle E, Schmidt H, Cavalieri M, Rao M, Hu F, Demirkan A, Oostra BA, de Andrade M, Turner ST, Ding J, Andrews JS, Freedman BI, Giulianini F, Koenig W, Illig T, Meisinger C, Gieger C, Zgaga L, Zemunik T, Boban M, Minelli C, Wheeler HE, Igl W, Zaboli G, Wild SH, Wright AF, Campbell H, Ellinghaus D, N\u00f6thlings U, Jacobs G, Biffar R, Ernst F, Homuth G, Kroemer HK, Nauck M, Stracke S, V\u00f6lker U, V\u00f6lzke H, Kovacs P, Stumvoll M, M\u00e4gi R, Hofman A, Uitterlinden AG, Rivadeneira F, Aulchenko YS, Polasek O, Hastie N, Vitart V, Helmer C, Wang JJ, Stengel B, Ruggiero D, Bergmann S, K\u00e4h\u00f6nen M, Viikari J, Nikopensius T, Province M, Ketkar S, Colhoun H, Doney A, Robino A, Kr\u00e4mer BK, Portas L, Ford I, Buckley BM, Adam M, Thun GA, Paulweber B, Haun M, Sala C, Mitchell P, Ciullo M, Kim SK, Vollenweider P, Raitakari O, Metspalu A, Palmer C, Gasparini P, Pirastu M, Jukema JW, Probst-Hensch NM, Kronenberg F, Toniolo D, Gudnason V, Shuldiner AR, Coresh J, Schmidt R, Ferrucci L, Siscovick DS, van Duijn CM, Borecki IB, Kardia SL, Liu Y, Curhan GC, Rudan I, Gyllensten U, Wilson JF, Franke A, Pramstaller PP, Rettig R, Prokopenko I, Witteman J, Hayward C, Ridker PM, Parsa A, Bochud M, Heid IM, Kao WH, Fox CS, K\u00f6ttgen A.\u00a0<strong>Integration of genome-wide association studies with biological knowledge identifies six novel genes related to kidney function.<\/strong>\u00a0Hum Mol Genet. 2012;21(24):5329-43. Epub 2012 Sep 8<\/p>\n<p>Davydov DM, Stewart R, Ritchie K, Chaudieu I.\u00a0<strong>Depressed mood and blood pressure: the moderating effect of situation-specific arousal levels.<\/strong>\u00a0Int J Psychophysiol. 2012;85(2):212-23. Epub 2012 May 1 (cohorte esprit)<\/p>\n<p>De Hollander EL, Bemelmans WJ, Boshuizen HC, Friedrich N, Wallaschofski H, Guallar-Castill\u00f3n P, Walter S, Zillikens MC, Rosengren A, Lissner L, Bassett JK, Giles GG, Orsini N, Heim N, Visser M, de Groot LC; WC elderly collaborators.\u00a0<strong>The association between waist circumference and risk of mortality considering body mass index in 65- to 74-year-olds: a meta-analysis of 29 cohorts involving more than 58 000 elderly persons.<\/strong>\u00a0Int J Epidemiol. 2012 Jun;41(3):805-17. Epub 2012 Mar 31<\/p>\n<p>Delcourt C, Delyfer MN, Rougier MB, Lambert JC, Amouyel P, Colin J, Malet F, Le Goff M, Dartigues JF, Korobelnik JF.\u00a0<strong>ARMS2 A69S polymorphism and the risk for age-related maculopathy: the ALIENOR study.<\/strong>\u00a0Arch Ophthalmol. 2012 Aug 1;130(8):1077-8<\/p>\n<p>Dumurgier J, Crivello F, Mazoyer B, Ahmed I, Tavernier B, Grabli D, Fran\u00e7ois C, Tzourio-Mazoyer N, Tzourio C, Elbaz A.\u00a0<strong>MRI atrophy of the caudate nucleus and slower walking speed in the elderly. Neuroimage.<\/strong>\u00a02012 Apr 2;60(2):871-8. Epub 2012 Jan 28<\/p>\n<p>Feart C, Alles B, Merle B, Samieri C, Barberger-Gateau P.\u00a0<strong>Adherence to a Mediterranean diet and energy, macro-, and micronutrient intakes in older persons.<\/strong>\u00a0J Physiol Biochem. 2012;68(4):691-700. Epub 2012 Jul 4<\/p>\n<p>Foubert-Samier A, Catheline G, Amieva H, Dilharreguy B, Helmer C, Allard M, Dartigues JF.<strong>\u00a0Education, occupation, leisure activities, and brain reserve: a population-based study.<\/strong>\u00a0Neurobiol Aging. 2012 Feb;33(2):423.e15-25.Epub 2010 Nov 12<\/p>\n<p>Germain M, Saut N, Oudot-Mellakh T, Letenneur L, Dupuy AM, Bertrand M, Alessi MC, Lambert JC, Zelenika D, Emmerich J, Tiret L, Cambien F, Lathrop M, Amouyel P, Morange PE, Tr\u00e9gou\u00ebt DA.\u00a0<strong>Caution in interpreting results from imputation analysis when linkage disequilibrium extends over a large distance: a case study on venous thrombosis.<\/strong>\u00a0PLoS One. 2012;7(6):e38538. Epub 2012 Jun 4<\/p>\n<p>Glymour MM, Ch\u00eane G, Tzourio C, Dufouil C.\u00a0<strong>Brain MRI markers and dropout in a longitudinal study of cognitive aging: The Three-City Dijon Study.<\/strong>\u00a0Neurology. 2012 Sep 25;79(13):1340-8. Epub 2012 Sep 12.<\/p>\n<p>Glymour MM, Tzourio C, Dufouil C.\u00a0<strong>Is cognitive aging predicted by one&rsquo;s own or one&rsquo;s parents&rsquo; educational level? results from the three-city study.<\/strong>\u00a0Am J Epidemiol. 2012 Apr 15;175(8):750-9. Epub 2012 Apr 2.<\/p>\n<p>Godin O, Elbejjani M, Kaufman JS. <strong>Body mass index, blood pressure, and risk of depression in the elderly: a marginal structural model<\/strong>. Am J Epidemiol. 2012;176(3):204-13. Epub 2012 Jul 10<\/p>\n<p>Hamilton G, Killick R; Genetic and Environmental Risk for Alzheimer&rsquo;s Disease Consortium; Translational Genomics Research Institute Consortium, Lambert JC, Amouyel P; European Alzheimer Disease Initiative, Carrasquillo MM, Pankratz VS, Graff-Radford NR, Dickson DW, Petersen RC, Younkin SG, Powell JF, Wade-Martins R.\u00a0<strong>Functional and genetic analysis of haplotypic sequence variation at the nicastrin genomic locus.<\/strong>\u00a0Neurobiol Aging. 2012 Aug;33(8):1848.e1-13. Epub 2012 Mar 8.<\/p>\n<p>Hong MG, Reynolds CA, Feldman AL, Kallin M, Lambert JC, Amouyel P, Ingelsson E, Pedersen NL, Prince JA.\u00a0<strong>Genome-wide and gene-based association implicates FRMD6 in Alzheimer disease.<\/strong>Hum Mutat. 2012 Mar;33(3):521-9. Epub 2012 Jan 23<\/p>\n<p>Jaussent I, Bouyer J, Ancelin ML, Berr C, Foubert-Samier A, Ritchie K, Ohayon MM, Besset A, Dauvilliers Y.\u00a0<strong>Excessive Sleepiness is Predictive of Cognitive Decline in the Elderly.<\/strong>\u00a0Sleep. 2012;35(9):1201-7.<\/p>\n<p>Keller MF, Saad M, Bras J, Bettella F, Nicolaou N, Sim\u00f3n-S\u00e1nchez J, Mittag F, B\u00fcchel F, Sharma M, Gibbs JR, Schulte C, Moskvina V, Durr A, Holmans P, Kilarski LL, Guerreiro R, Hernandez DG, Brice A, Ylikotila P, Stef\u00e1nsson H, Majamaa K, Morris HR, Williams N, Gasser T, Heutink P, Wood NW, Hardy J, Martinez M, Singleton AB, Nalls MA; International Parkinson&rsquo;s Disease Genomics Consortium (IPDGC); Wellcome Trust Case Control Consortium 2 (WTCCC2).\u00a0<strong>Using genome-wide complex trait analysis to quantify &lsquo;missing heritability&rsquo; in Parkinson&rsquo;s disease.<\/strong>\u00a0Hum Mol Genet. 2012 Nov 15;21(22):4996-5009. Epub 2012 Aug 13.<\/p>\n<p>Leone N, Courbon D, Berr C, Barberger-Gateau P, Tzourio C, Alp\u00e9rovitch A, Zureik M.<strong>\u00a0Abdominal obesity and late-onset asthma: cross-sectional and longitudinal results: the 3C study.<\/strong>\u00a0Obesity (Silver Spring). 2012 Mar;20(3):628-35. Epub 2011 Oct 20<\/p>\n<p>Manetti M, Allanore Y, Saad M, Fatini C, Cohignac V, Guiducci S, Romano E, Air\u00f3 P, Caramaschi P, Tinazzi I, Riccieri V, Della Rossa A, Abbate R, Caporali R, Cuomo G, Valesini G, Dieud\u00e9 P, Hachulla E, Cracowski JL, Tiev K, Letenneur L, Amouyel P, Lambert JC, Chiocchia G, Martinez M, Ibba-Manneschi L, Matucci-Cerinic M.<strong>\u00a0Evidence for caveolin-1 as a new susceptibility gene regulating tissue fibrosis in systemic sclerosis.<\/strong>\u00a0Ann Rheum Dis. 2012;71(6):1034-41. Epub 2012 Mar 8<\/p>\n<p>Marti H, Carcaillon L, Chavance M.\u00a0<strong>Multiple imputation for estimating hazard ratios and predictive abilities in case-cohort surveys.<\/strong>\u00a0BMC Med Res Methodol. 2012;12:24. doi: 10.1186\/1471-2288-12-24<\/p>\n<p>Mittag F, B\u00fcchel F, Saad M, Jahn A, Schulte C, Bochdanovits Z, Sim\u00f3n-S\u00e1nchez J, Nalls MA, Keller M, Hernandez DG, Gibbs JR, Lesage S, Brice A, Heutink P, Martinez M, Wood NW, Hardy J, Singleton AB, Zell A, Gasser T, Sharma M; International Parkinson\u2019s Disease Genomics Consortium.\u00a0<strong>Use of support vector machines for disease risk prediction in genome-wide association studies: concerns and opportunities.<\/strong>\u00a0Hum Mutat. 2012 Dec;33(12):1708-18. Epub 2012 Aug 3.<\/p>\n<p>Noize P, Bazin F, Pariente A, Dufouil C, Ancelin ML, Helmer C, Moore N, Fourrier-R\u00e9glat A.<strong>\u00a0Validity of chronic drug exposure presumed from repeated patient interviews varied according to drug class.<\/strong>\u00a0J Clin Epidemiol. 2012;65(10):1061-8. doi: 10.1016\/j.jclinepi.2012.04.009. Epub 2012 Jul 21.<\/p>\n<p>Norton J, Ancelin ML, Stewart R, Berr C, Ritchie K, Carri\u00e8re I.\u00a0<strong>Anxiety symptoms and disorder predict activity limitations in the elderly.<\/strong>\u00a0J Affect Disord. 2012 Dec 10;141(2-3):276-85. doi: 10.1016\/j.jad.2012.04.002. 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Epub 2012 Mar 29<\/p>\n<p>Plichart M, Empana JP, Lambert JC, Amouyel P, Tiret L, Letenneur L, Berr C, Tzourio C, Ducimeti\u00e8re P.\u00a0<strong>Single polymorphism nucleotide rs1333049 on chromosome 9p21 is associated with carotid plaques but not with common carotid intima-media thickness in older adults. A combined analysis of the Three-City and the EVA studies.<\/strong>\u00a0Atherosclerosis. 2012 May;222(1):187-90. Epub 2012 Mar 3.<\/p>\n<p>Portet F, Brickman AM, Stern Y, Scarmeas N, Muraskin J, Provenzano FA, Berr C, Bonaf\u00e9 A, Artero S, Ritchie K, Akbaraly TN.\u00a0<strong>Metabolic syndrome and localization of white matter hyperintensities in the elderly population.<\/strong>\u00a0Alzheimers Dement. 2012;8(5 Suppl):S88-95.e1. 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Epub 2011 Nov 3.<\/p>\n<p>Ryan J, Ancelin ML.Polymorphisms of estrogen receptors and risk of depression: therapeutic implications.Drugs. 2012;72(13):1725-38. doi: 10.2165\/11635960-000000000-00000. Review<\/p>\n<p>Samieri C, Maillard P, Crivello F, Proust-Lima C, Peuchant E, Helmer C, Amieva H, Allard M, Dartigues JF, Cunnane SC, Mazoyer BM, Barberger-Gateau P.\u00a0<strong>Plasma long-chain omega-3 fatty acids and atrophy of the medial temporal lobe.<\/strong>\u00a0Neurology. 2012 Aug 14;79(7):642-50. Epub 2012 Aug 1.<\/p>\n<p>Satizabal CL, Zhu YC, Mazoyer B, Dufouil C, Tzourio C.\u00a0<strong>Circulating IL-6 and CRP are associated with MRI findings in the elderly: the 3C-Dijon Study.<\/strong>\u00a0Neurology. 2012 Mar 6;78(10):720-7. Epub 2012 Feb 22.<\/p>\n<p>Scarabin-Carr\u00e9 V, Canonico M, Brailly-Tabard S, Trabado S, Ducimeti\u00e8re P, Giroud M, Ryan J, Helmer C, Plu-Bureau G, Guiochon-Mantel A, Scarabin PY.<strong>\u00a0High level of plasma estradiol as a new predictor of ischemic arterial disease in older postmenopausal women: the three-city cohort study.<\/strong>\u00a0J Am Heart Assoc. 2012;1(3):e001388. 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Epub 2012 Jul 11.<\/p>\n<p>Soisson V, Brailly-Tabard S, Empana JP, F\u00e9art C, Ryan J, Bertrand M, Guiochon-Mantel A, Scarabin PY.\u00a0<strong>Low plasma testosterone and elevated carotid intima-media thickness: importance of low-grade inflammation in elderly men<\/strong>. Atherosclerosis. 2012;223(1):244-9. Epub 2012 May 16<\/p>\n<p>Stein JL, Medland SE, Vasquez AA, Hibar DP, Senstad RE, Winkler AM, Toro R, Appel K, Bartecek R, Bergmann \u00d8, Bernard M, Brown AA, Cannon DM, Chakravarty MM, Christoforou A, Domin M, Grimm O, Hollinshead M, Holmes AJ, Homuth G, Hottenga JJ, Langan C, Lopez LM, Hansell NK, Hwang KS, Kim S, Laje G, Lee PH, Liu X, Loth E, Lourdusamy A, Mattingsdal M, Mohnke S, Maniega SM, Nho K, Nugent AC, O&rsquo;Brien C, Papmeyer M, P\u00fctz B, Ramasamy A, Rasmussen J, Rijpkema M, Risacher SL, Roddey JC, Rose EJ, Ryten M, Shen L, Sprooten E, Strengman E, Teumer A, Trabzuni D, Turner J, van Eijk K, van Erp TG, van Tol MJ, Wittfeld K, Wolf C, Woudstra S, Aleman A, Alhusaini S, Almasy L, Binder EB, Brohawn DG, Cantor RM, Carless MA, Corvin A, Czisch M, Curran JE, Davies G, de Almeida MA, Delanty N, Depondt C, Duggirala R, Dyer TD, Erk S, Fagerness J, Fox PT, Freimer NB, Gill M, G\u00f6ring HH, Hagler DJ, Hoehn D, Holsboer F, Hoogman M, Hosten N, Jahanshad N, Johnson MP, Kasperaviciute D, Kent JW Jr, Kochunov P, Lancaster JL, Lawrie SM, Liewald DC, Mandl R, Matarin M, Mattheisen M, Meisenzahl E, Melle I, Moses EK, M\u00fchleisen TW, Nauck M, N\u00f6then MM, Olvera RL, Pandolfo M, Pike GB, Puls R, Reinvang I, Renter\u00eda ME, Rietschel M, Roffman JL, Royle NA, Rujescu D, Savitz J, Schnack HG, Schnell K, Seiferth N, Smith C, Steen VM, Vald\u00e9s Hern\u00e1ndez MC, Van den Heuvel M, van der Wee NJ, Van Haren NE, Veltman JA, V\u00f6lzke H, Walker R, Westlye LT, Whelan CD, Agartz I, Boomsma DI, Cavalleri GL, Dale AM, Djurovic S, Drevets WC, Hagoort P, Hall J, Heinz A, Jack CR Jr, Foroud TM, Le Hellard S, Macciardi F, Montgomery GW, Poline JB, Porteous DJ, Sisodiya SM, Starr JM, Sussmann J, Toga AW, Veltman DJ, Walter H, Weiner MW; Alzheimer&rsquo;s Disease Neuroimaging Initiative; EPIGEN Consortium; IMAGEN Consortium; Saguenay Youth Study Group, Bis JC, Ikram MA, Smith AV, Gudnason V, Tzourio C, Vernooij MW, Launer LJ, DeCarli C, Seshadri S; Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium, Andreassen OA, Apostolova LG, Bastin ME, Blangero J, Brunner HG, Buckner RL, Cichon S, Coppola G, de Zubicaray GI, Deary IJ, Donohoe G, de Geus EJ, Espeseth T, Fern\u00e1ndez G, Glahn DC, Grabe HJ, Hardy J, Hulshoff Pol HE, Jenkinson M, Kahn RS, McDonald C, McIntosh AM, McMahon FJ, McMahon KL, Meyer-Lindenberg A, Morris DW, M\u00fcller-Myhsok B, Nichols TE, Ophoff RA, Paus T, Pausova Z, Penninx BW, Potkin SG, S\u00e4mann PG, Saykin AJ, Schumann G, Smoller JW, Wardlaw JM, Weale ME, Martin NG, Franke B, Wright MJ, Thompson PM; Enhancing Neuro Imaging Genetics through Meta-Analysis Consortium.\u00a0<strong>Identification of common variants associated with human hippocampal and intracranial volumes.<\/strong>\u00a0Nat Genet. 2012 Apr 15;44(5):552-61. doi: 10.1038\/ng.2250.<\/p>\n<p>Tregouet DA, Sabater-Lleal M, Bruzelius M, Emmerich J, Amouyel P, Dartigues JF, Kieler H, Morange PE.\u00a0<strong>Lack of association of non-synonymous FUT2 and ALPL polymorphisms with venous thrombosis.<\/strong>\u00a0J Thromb Haemost. 2012 Aug;10(8):1693-5.<\/p>\n<p>Zhu YC, Chabriat H, Godin O, Dufouil C, Rosand J, Greenberg SM, Smith EE, Tzourio C, Viswanathan A.\u00a0<strong>Distribution of white matter hyperintensity in cerebral hemorrhage and healthy aging.<\/strong>\u00a0J Neurol. 2012;259(3):530-6<\/p>\n<\/div><\/div><\/div><\/div><\/div><style type=\"text\/css\">.fusion-accordian  #accordion-880-12 .panel-title a .fa-fusion-box{ color: #ffffff;}.fusion-accordian  #accordion-880-12 .panel-title a .fa-fusion-box:before{ font-size: 16px; width: 16px;}.fusion-accordian  #accordion-880-12 .panel-title a{font-size:24px;}.fusion-accordian  #accordion-880-12 .fa-fusion-box { background-color: #212934;border-color: #212934;}.fusion-accordian  #accordion-880-12 .panel-title a:hover, #accordion-880-12 .fusion-toggle-boxed-mode:hover .panel-title a { color: #65bc7b;}.fusion-accordian  #accordion-880-12 .panel-title .active .fa-fusion-box,.fusion-accordian  #accordion-880-12 .panel-title a:hover .fa-fusion-box { background-color: #65bc7b!important;border-color: #65bc7b!important;}<\/style><div class=\"accordian fusion-accordian\"><div class=\"panel-group\" id=\"accordion-880-12\"><div class=\"fusion-panel panel-default\"><div class=\"panel-heading\"><h4 class=\"panel-title toggle\"><a aria-expanded=\"false\" aria-controls=\"f6e3ebfb3654d1e9c\" role=\"button\" data-toggle=\"collapse\" data-parent=\"#accordion-880-12\" data-target=\"#f6e3ebfb3654d1e9c\" href=\"#f6e3ebfb3654d1e9c\"><span class=\"fusion-toggle-icon-wrapper\" aria-hidden=\"true\"><i class=\"fa-fusion-box\" aria-hidden=\"true\"><\/i><\/span><span class=\"fusion-toggle-heading\">2013<\/span><\/a><\/h4><\/div><div id=\"f6e3ebfb3654d1e9c\" class=\"panel-collapse collapse \"><div class=\"panel-body toggle-content fusion-clearfix\">Ancelin ML, Ripoche E, Dupuy AM, Barberger-Gateau P, Auriacombe S, Rouaud O, Berr C, Carri\u00e8re I, Ritchie K.\u00a0<strong>Sex differences in the associations between lipid levels and incident dementia.<\/strong>\u00a0J Alzheimers Dis. 2013 Jan 1;34(2):519-28. doi: 10.3233\/JAD-121228<\/p>\n<p>Ancelin ML, Carri\u00e8re I, Scali J, Ritchie K, Chaudieu I, Ryan J. <strong>Angiotensin-converting enzyme gene variants are associated with both cortisol secretion and late-life depression.<\/strong> Transl Psy chiatry. 2013 Nov 5;3:e322. doi: 10.1038\/tp.2013.95<\/p>\n<p>Artaud F, Dugravot A, Sabia S, Singh-Manoux A, Tzourio C, Elbaz A. <strong>Unhealthy behaviours and disability in older adults: the Three-City Dijon cohort study.<\/strong> BMJ 2013;347:f4240. doi: 10.1136\/bmj.f4240<\/p>\n<p>Barberger-Gateau P, Lambert JC, F\u00e9art C, P\u00e9r\u00e8s K, Ritchie K, Dartigues JF, Alp\u00e9rovitch A.\u00a0<strong>From genetics to dietetics: the contribution of epidemiology to understanding Alzheimer&rsquo;s disease.<\/strong>\u00a0J Alzheimers Dis. 2013;33 Suppl 1:S457-63<\/p>\n<p>Brisset M, Boutouyrie P, Pico F, Zhu Y, Zureik M, Schilling S, Dufouil C, Mazoyer B, Laurent S, Tzourio C, Debette S.\u00a0<strong>Large-vessel correlates of cerebral small-vessel disease.<\/strong>\u00a0Neurology. 2013 Feb 12;80(7):662-669. Epub 2013 Jan 23.<\/p>\n<p>Cacciolati C, Tzourio C, Hanon O.\u00a0<strong>Blood pressure variability in elderly persons with white-coat and masked hypertension compared to those with normotension and sustained hypertension.<\/strong>\u00a0Am J Hypertens. 2013 Mar;26(3):367-72. Epub 2012 Dec 21<\/p>\n<p>Cacciolati C, Hanon O, Dufouil C, Alp\u00e9rovitch A, Tzourio C.<strong>\u00a0Categories of hypertension in the elderly and their 1-year evolution. The Three-City Study.<\/strong>\u00a0J Hypertens. 2013 Apr;31(4):680-9. doi: 10.1097\/HJH.0b013e32835ee0ca<\/p>\n<p>Carri\u00e8re I, Delcourt C, Daien V, P\u00e9r\u00e8s K, F\u00e9art C, Berr C, Laure Ancelin M, Ritchie K. <strong>A prospective study of the bi-directional association between vision loss and depression in the elderly<\/strong>. J Affect Disord. 2013;151(1):164-70. Epub 2013 Jun 1<\/p>\n<p>Carri\u00e8re I, Ryan J, Norton J, Scali J, Stewart R, Ritchie K, Ancelin ML. <strong>Anxiety and mortality risk in community-dwelling elderly people.<\/strong> Br J Psychiatry. 2013;203(3):303-9. Epub 2013 Aug 8<\/p>\n<p>Chapuis J, Hansmannel F, Gistelinck M, Mounier A, Van Cauwenberghe C, Kolen KV, Geller F, Sottejeau Y, Harold D, Dourlen P, Grenier-Boley B, Kamatani Y, Delepine B, Demiautte F, Zelenika D, Zommer N, Hamdane M, Bellenguez C, Dartigues JF, Hauw JJ, Letronne F, Ayral AM, Sleegers K, Schellens A, Broeck LV, Engelborghs S, De Deyn PP, Vandenberghe R, O&rsquo;Donovan M, Owen M, Epelbaum J, Mercken M, Karran E, Bantscheff M, Drewes G, Joberty G, Campion D, Octave JN, Berr C, Lathrop M, Callaerts P, Mann D, Williams J, Bu\u00e9e L, Dewachter I, Van Broeckhoven C, Amouyel P, Moechars D, Dermaut B, Lambert JC. <strong>Increased expression of BIN1 mediates Alzheimer genetic risk by modulating tau pathology.<\/strong> Mol Psychiatry. 2013;18(11):1225-34<\/p>\n<p>Cheng CY, Schache M, Ikram MK, Young TL, Guggenheim JA, Vitart V, Macgregor S, Verhoeven VJ, Barathi VA, Liao J, Hysi PG, Bailey-Wilson JE, St Pourcain B, Kemp JP, McMahon G, Timpson NJ, Evans DM, Montgomery GW, Mishra A, Wang YX, Wang JJ, Rochtchina E, Polasek O, Wright AF, Amin N, van Leeuwen EM, Wilson JF, Pennell CE, van Duijn CM, de Jong PT, Vingerling JR, Zhou X, Chen P, Li R, Tay WT, Zheng Y, Chew M; Consortium for Refractive Error and Myopia, Burdon KP, Craig JE, Iyengar SK, Igo RP Jr, Lass JH Jr; The Fuchs\u2019 Genetics Multi-Center Study Group, Chew EY, Haller T, Mihailov E, Metspalu A, Wedenoja J, Simpson CL, Wojciechowski R, H\u00f6hn R, Mirshahi A, Zeller T, Pfeiffer N, Lackner KJ; Wellcome Trust Case Control Consortium 2, Bettecken T, Meitinger T, Oexle K, Pirastu M, Portas L, Nag A, Williams KM, Yonova-Doing E, Klein R, Klein BE, Hosseini SM, Paterson AD; Diabetes Control and Complications Trial\/Epidemiology of Diabetes Interventions, and Complications Research Group, Makela KM, Lehtimaki T, Kahonen M, Raitakari O, Yoshimura N, Matsuda F, Chen LJ, Pang CP, Yip SP, Yap MK, Meguro A, Mizuki N, Inoko H, Foster PJ, Zhao JH, Vithana E, Tai ES, Fan Q, Xu L, Campbell H, Fleck B, Rudan I, Aung T, Hofman A, Uitterlinden AG, Bencic G, Khor CC, Forward H, P\u00e4rssinen O, Mitchell P, Rivadeneira F, Hewitt AW, Williams C, Oostra BA, Teo YY, Hammond CJ, Stambolian D, Mackey DA, Klaver CC, Wong TY, Saw SM, Baird PN. <strong>Nine Loci for Ocular Axial Length Identified through Genome-wide Association Studies, Including Shared Loci with Refractive Error.<\/strong> Am J Hum Genet. 2013;93(2):264-77<\/p>\n<p>Cougnard-Gr\u00e9goire A, Delyfer MN, Korobelnik JF, Rougier MB, Malet F, Le Goff M, Dartigues JF, Colin J, Barberger-Gateau P, Delcourt C.\u00a0<strong>Long-Term Blood Pressure and Age-Related Macular Degeneration: The ALIENOR Study.<\/strong>\u00a0Invest Ophthalmol Vis Sci. 2013;54(3):1905-12.<\/p>\n<p>Culverhouse RC, Bowes L, Breslau N, Nurnberger JI Jr, Burmeister M, Fergusson DM, Munaf\u00f2 M, Saccone NL, Bierut LJ; 5-HTTLPR, Stress, and Depression Consortium. <strong>Protocol for a collaborative meta-analysis of 5-HTTLPR, stress, and depression.<\/strong> BMC Psychiatry. 2013 Nov 12;13:304. doi: 10.1186\/1471-244X-13-304<\/p>\n<p>Danaei G, Singh GM, Paciorek CJ, Lin JK, Cowan MJ, Finucane MM, Farzadfar F, Stevens GA, Riley LM, Lu Y, Rao M, Ezzati M; Global Burden of Metabolic Risk Factors of Chronic Diseases Collaborating Group.<strong> The global cardiovascular risk transition: associations of four metabolic risk factors with national income, urbanization, and Western diet in 1980 and 2008.<\/strong> Circulation. 2013;127(14):1493-502, 1502e1-8. doi: 10.1161\/CIRCULATIONAHA.113.001470. Epub 2013 Mar 12<\/p>\n<p>Dartigues JF, Foubert-Samier A, Helmer C.<strong> Relationship between educational level and dementia: Social factor and age-related chronic disease.<\/strong> Rev Epidemiol Sante Publique. 2013;61 Suppl 3:S195-8. Epub 2013 Jul 5. French<\/p>\n<p>Delva F, Pimouguet C, Helmer C, P\u00e9res K, Br\u00e9chat B, Le Goff M, Jacqmin-Gadda H, Amieva H, Orgogozo JM, Auriacombe S, Berr C, Tzourio C, Barberger-Gateau P, Dartigues JF. <strong>A Simple Score to Predict Survival with Dementia in the General Population.<\/strong> Neuroepidemiology. 2013;41(1):20-28. Epub 2013 Mar 19<\/p>\n<p>Elbaz A, Vicente-Vytopilova P, Tavernier B, Sabia S, Dumurgier J, Mazoyer B, Singh-Manoux A, Tzourio C.<strong> Motor function in the elderly: evidence for the reserve hypothesis.<\/strong> Neurology 2013;81:417-426. Epub 2013 Jun 26<\/p>\n<p>Engberink AO, Pimouguet C, Amouyal M, Gerassimo O, Bourrel G, Berr C. <strong>Determinants of support for dementia patients in general practice: a qualitative approach based on an epidemiological cohort.<\/strong> Geriatr Psychol Neuropsychiatr Vieil. 2013;11(2):157-167<\/p>\n<p>Feart C, Lorrain S, Ginder Coupez V, Samieri C, Letenneur L, Paineau D, Barberger-Gateau P. <strong>Adherence to a Mediterranean diet and risk of fractures in French older persons.<\/strong> Osteoporos Int. 2013;24(12):3031-41. Epub 2013 Jun 20<\/p>\n<p>F\u00e9art C, Samieri C, All\u00e8s B, Barberger-Gateau P. <strong>Potential benefits of adherence to the Mediterranean diet on cognitive health.<\/strong> Proc Nutr Soc. 2013;72(1):140-52. Epub 2012 Dec 11<\/p>\n<p>Gabelle A, Richard F, Gutierrez LA, Schraen S, Delva F, Rouaud O, Bu\u00e9e L, Dartigues JF, Touchon J, Lambert JC, Berr C.\u00a0<strong>Plasma amyloid-\u03b2 levels and prognosis in incident dementia cases of the 3-City Study.<\/strong>\u00a0J Alzheimers Dis. 2013;33(2):381-91<\/p>\n<p>Genziani M, Stewart R, B\u00e9jot Y, Amieva H, Artero S, Ritchie K.\u00a0<strong>Subjective memory impairment, objective cognitive functioning and social activity in French older people: findings from the Three Cities study.<\/strong>\u00a0Geriatr Gerontol Int. 2013 Jan;13(1):139-45. Epub 2012 Jun 7<\/p>\n<p>Germain M, Eyries M, Montani D, Poirier O, Girerd B, Dorfm\u00fcller P, Coulet F, Nadaud S, Maugenre S, Guignabert C, Carpentier W, Vonk-Noordegraaf A, L\u00e9vy M, Chaouat A, Lambert JC, Bertrand M, Dupuy AM, Letenneur L, Lathrop M, Amouyel P, de Ravel TJ, Delcroix M, Austin ED, Robbins IM, Hemnes AR, Loyd JE, Berman-Rosenzweig E, Barst RJ, Chung WK, Simonneau G, Tr\u00e9gou\u00ebt DA, Humbert M, Soubrier F. <strong>Genome-wide association analysis identifies a susceptibility locus for pulmonary arterial hypertension.<\/strong> Nat Genet. 2013;45(5):518-21. Epub 2013 Mar 17<\/p>\n<p>Guerreiro R, Wojtas A, Bras J, Carrasquillo M, Rogaeva E, Majounie E, Cruchaga C, Sassi C, Kauwe JS, Younkin S, Hazrati L, Collinge J, Pocock J, Lashley T, Williams J, Lambert JC, Amouyel P, Goate A, Rademakers R, Morgan K, Powell J, St George-Hyslop P, Singleton A, Hardy J;<strong>\u00a0Alzheimer Genetic Analysis Group. TREM2 variants in Alzheimer&rsquo;s disease.<\/strong>\u00a0N Engl J Med. 2013 Jan 10;368(2):117-27. Epub 2012 Nov 14<\/p>\n<p>Greliche N, Germain M, Lambert JC, Cohen W, Bertrand M, Dupuis AM, Letenneur L, Lathrop M, Amouyel P, Morange PE, Tr\u00e9gou\u00ebt DA.\u00a0<strong>A genome-wide search for common SNP x SNP interactions on the risk of venous thrombosis.<\/strong>\u00a0BMC Med Genet. 2013;14:36. doi: 10.1186\/1471-2350-14-36<\/p>\n<p>Grimaud O, Lapostolle A, Berr C, Helmer C, Dufouil C, Kihal W, Alp\u00e9rovitch A, Chauvin P. <strong>Gender differences in the association between socioeconomic status and subclinical atherosclerosis.<\/strong> PLoS One. 2013;8(11):e80195<\/p>\n<p>Helmer C, Malet F, Rougier MB, Schweitzer C, Colin J, Delyfer MN, Korobelnik JF, Barberger-Gateau P, Dartigues JF, Delcourt C. <strong>Is there a link between open-angle glaucoma and dementia? The 3C-alienor cohort.<\/strong> Ann Neurol. 2013;74(2):171-9<\/p>\n<p>Holmans P, Moskvina V, Jones L, Sharma M; International Parkinson&rsquo;s Disease Genomics Consortium, Vedernikov A, Buchel F, Sadd M, Bras JM, Bettella F, Nicolaou N, Sim\u00f3n-S\u00e1nchez J, Mittag F, Gibbs JR, Schulte C, Durr A, Guerreiro R, Hernandez D, Brice A, Stef\u00e1nsson H, Majamaa K, Gasser T, Heutink P, Wood NW, Martinez M, Singleton AB, Nalls MA, Hardy J, Morris HR, Williams NM.\u00a0<strong>A pathway-based analysis provides additional support for an immune-related genetic susceptibility to Parkinson&rsquo;s disease.<\/strong>\u00a0Hum Mol Genet. 2013 Mar 1;22(5):1039-49. Epub 2012 Dec 7<\/p>\n<p>Jaussent I, Empana JP, Ancelin ML, Besset A, Helmer C, Tzourio C, Ritchie K, Bouyer J, Dauvilliers Y.\u00a0<strong>Insomnia, daytime sleepiness and cardio-cerebrovascular diseases in the elderly: a 6-year prospective study.<\/strong>\u00a0PLoS One. 2013;8(2):e56048. Epub 2013 Feb 14<\/p>\n<p>Jaussent I, Ancelin ML, Berr C, P\u00e9r\u00e8s K, Scali J, Besset A, Ritchie K, Dauvilliers Y. <strong>Hypnotics and mortality in an elderly general population: a 12-year prospective study.<\/strong> BMC Med. 2013;11(1):212<\/p>\n<p>Klebe S, Golmard JL, Nalls MA, Saad M, Singleton AB, Bras JM, Hardy J, Simon-Sanchez J, Heutink P, Kuhlenb\u00e4umer G, Charfi R, Klein C, Hagenah J, Gasser T, Wurster I, Lesage S, Lorenz D, Deuschl G, Durif F, Pollak P, Damier P, Tison F, Durr A, Amouyel P, Lambert JC, Tzourio C, Maubaret C, Charbonnier-Beaupel F, Tahiri K, Vidailhet M, Martinez M, Brice A, Corvol JC; French Parkinson&rsquo;s Disease Genetics Study Group and the International Parkinson&rsquo;s Disease Genomics Consortium (IPDGC).<strong> The Val158Met COMT polymorphism is a modifier of the age at onset in Parkinson&rsquo;s disease with a sexual dimorphism.<\/strong> J Neurol Neurosurg Psychiatry. 2013;84(6):666-73. doi: 10.1136\/jnnp-2012-304475. Epub 2013 Feb 13<\/p>\n<p>Koumakis E, Bouaziz M, Dieud\u00e9 P, Ruiz B, Riemekasten G, Airo P, M\u00fcller-Nurasyid M, Cusi D, Matucci-Cerinic M, Melchers I, Salvi E, Strauch K, Peters A, Cuomo G, Hachulla E, Diot E, Hunzelmann N, Caramaschi P, Riccieri V, Distler JH, Tarner I, Avouac J, Letenneur L, Amouyel P, Lambert JC, Chiocchia G, Boileau C, Allanore Y. <strong>A regulatory variant in CCR6 is associated with anti-topoisomerase positive systemic sclerosis susceptibility.<\/strong> Arthritis Rheum. 2013;65(12):3202-8<\/p>\n<p>Lambert JC, Grenier-Boley B, Harold D, Zelenika D, Chouraki V, Kamatani Y, Sleegers K, Ikram MA, Hiltunen M, Reitz C, Mateo I, Feulner T, Bullido M, Galimberti D, Concari L, Alvarez V, Sims R, Gerrish A, Chapman J, Deniz-Naranjo C, Solfrizzi V, Sorbi S, Arosio B, Spalletta G, Siciliano G, Epelbaum J, Hannequin D, Dartigues JF, Tzourio C, Berr C, Schrijvers EM, Rogers R, Tosto G, Pasquier F, Bettens K, Van Cauwenberghe C, Fratiglioni L, Graff C, Delepine M, Ferri R, Reynolds CA, Lannfelt L, Ingelsson M, Prince JA, Chillotti C, Pilotto A, Seripa D, Boland A, Mancuso M, Boss\u00f9 P, Annoni G, Nacmias B, Bosco P, Panza F, Sanchez-Garcia F, Del Zompo M, Coto E, Owen M, O&rsquo;Donovan M, Valdivieso F, Caffarra P, Scarpini E, Combarros O, Bu\u00e9e L, Campion D, Soininen H, Breteler M, Riemenschneider M, Van Broeckhoven C, Alp\u00e9rovitch A, Lathrop M, Tr\u00e9gou\u00ebt DA, Williams J, Amouyel P.<strong>\u00a0Genome-wide haplotype association study identifies the FRMD4A gene as a risk locus for Alzheimer&rsquo;s disease.<\/strong>\u00a0Mol Psychiatry. 2013 Apr;18(4):461-70. doi: 10.1038\/mp.2012.14. Epub 2012 Mar 20.<\/p>\n<p>Lambert JC, Ibrahim-Verbaas CA, Harold D, Naj AC, Sims R, Bellenguez C, Jun G, Destefano AL, Bis JC, Beecham GW, Grenier-Boley B, Russo G, Thornton-Wells TA, Jones N, Smith AV, Chouraki V, Thomas C, Ikram MA, Zelenika D, Vardarajan BN, Kamatani Y, Lin CF, Gerrish A, Schmidt H, Kunkle B, Dunstan ML, Ruiz A, Bihoreau MT, Choi SH, Reitz C, Pasquier F, Hollingworth P, Ramirez A, Hanon O, Fitzpatrick AL, Buxbaum JD, Campion D, Crane PK, Baldwin C, Becker T, Gudnason V, Cruchaga C, Craig D, Amin N, Berr C, Lopez OL, De Jager PL, Deramecourt V, Johnston JA, Evans D, Lovestone S, Letenneur L, Mor\u00f3n FJ, Rubinsztein DC, Eiriksdottir G, Sleegers K, Goate AM, Fi\u00e9vet N, Huentelman MJ, Gill M, Brown K, Kamboh MI, Keller L, Barberger-Gateau P, McGuinness B, Larson EB, Green R, Myers AJ, Dufouil C, Todd S, Wallon D, Love S, Rogaeva E, Gallacher J, St George-Hyslop P, Clarimon J, Lleo A, Bayer A, Tsuang DW, Yu L, Tsolaki M, Boss\u00f9 P, Spalletta G, Proitsi P, Collinge J, Sorbi S, Sanchez-Garcia F, Fox NC, Hardy J, Naranjo MC, Bosco P, Clarke R, Brayne C, Galimberti D, Mancuso M, Matthews F; European Alzheimer&rsquo;s Disease Initiative (EADI); Genetic and Environmental Risk in Alzheimer&rsquo;s Disease (GERAD); Alzheimer&rsquo;s Disease Genetic Consortium (ADGC); Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE), Moebus S, Mecocci P, Del Zompo M, Maier W, Hampel H, Pilotto A, Bullido M, Panza F, Caffarra P, Nacmias B, Gilbert JR, Mayhaus M, Lannfelt L, Hakonarson H, Pichler S, Carrasquillo MM, Ingelsson M, Beekly D, Alvarez V, Zou F, Valladares O, Younkin SG, Coto E, Hamilton-Nelson KL, Gu W, Razquin C, Pastor P, Mateo I, Owen MJ, Faber KM, Jonsson PV, Combarros O, O&rsquo;Donovan MC, Cantwell LB, Soininen H, Blacker D, Mead S, Mosley TH Jr, Bennett DA, Harris TB, Fratiglioni L, Holmes C, de Bruijn RF, Passmore P, Montine TJ, Bettens K, Rotter JI, Brice A, Morgan K, Foroud TM, Kukull WA, Hannequin D, Powell JF, Nalls MA, Ritchie K, Lunetta KL, Kauwe JS, Boerwinkle E, Riemenschneider M, Boada M, Hiltunen M, Martin ER, Schmidt R, Rujescu D, Wang LS, Dartigues JF, Mayeux R, Tzourio C, Hofman A, N\u00f6then MM, Graff C, Psaty BM, Jones L, Haines JL, Holmans PA, Lathrop M, Pericak-Vance MA, Launer LJ, Farrer LA, van Duijn CM, Van Broeckhoven C, Moskvina V, Seshadri S, Williams J, Schellenberg GD, Amouyel P. <strong>Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer&rsquo;s disease<\/strong>. Nat Genet. 2013 Dec;45(12):1452-8<\/p>\n<p>Merle BM, Delyfer MN, Korobelnik JF, Rougier MB, Malet F, F\u00e9art C, Le Goff M, Peuchant E, Letenneur L, Dartigues JF, Colin J, Barberger-Gateau P, Delcourt C. <strong>High Concentrations of Plasma n3 Fatty Acids Are Associated with Decreased Risk for Late Age-Related Macular Degeneration.<\/strong>\u00a0J Nutr. 2013 Apr;143(4):505-11. Epub 2013 Feb 13.<\/p>\n<p>Merle BM, Maubaret C, Korobelnik JF, Delyfer MN, Rougier MB, Lambert JC, Amouyel P, Malet F, Le Goff M, Dartigues JF, Barberger-Gateau P, Delcourt C. <strong>Association of HDL-Related Loci with Age-Related Macular Degeneration and Plasma Lutein and Zeaxanthin: the Alienor Study.<\/strong> PLoS One. 2013;8(11):e79848<\/p>\n<p>Mortamais M, Reynes C, Brickman AM, Provenzano FA, Muraskin J, Portet F, Berr C, Touchon J, Bonaf\u00e9 A, le Bars E, Maller JJ, Meslin C, Sabatier R, Ritchie K, Artero S.\u00a0<strong>Spatial distribution of cerebral white matter lesions predicts progression to mild cognitive impairment and dementia.<\/strong>\u00a0PLoS One. 2013;8(2):e56972. Epub 2013 Feb 14. 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Epub 2013 Sep 12<\/p>\n<p>P\u00e9quignot R, Tzourio C, P\u00e9res K, Ancellin ML, Perier MC, Ducimeti\u00e8re P, Empana JP.\u00a0<strong>Depressive symptoms, antidepressants and disability and future coronary heart disease and stroke events in older adults: the Three City Study.<\/strong>\u00a0Eur J Epidemiol. 2013 Mar;28(3):249-56. Epub 2013 Jan 22.<\/p>\n<p>Pichler I, Del Greco M F, G\u00f6gele M, Lill CM, Bertram L, Do CB, Eriksson N, Foroud T, Myers RH; PD GWAS Consortium, Nalls M, Keller MF; International Parkinson&rsquo;s Disease Genomics Consortium; Wellcome Trust Case Control Consortium 2, Benyamin B, Whitfield JB; Genetics of Iron Status Consortium, Pramstaller PP, Hicks AA, Thompson JR, Minelli C. <strong>Serum iron levels and the risk of Parkinson disease: a mendelian randomization study.<\/strong> PLoS Med. 2013;10(6):e1001462. doi: 10.1371\/journal.pmed.1001462. Epub 2013 Jun 4. 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Epub 2013 Mar 26<\/p>\n<p>Ritchie K, Norton J, Mann A, Carri\u00e8re I, Ancelin ML.<strong> Late-Onset Agoraphobia: General Population Incidence and Evidence for a Clinical Subtype.<\/strong> Am J Psychiatry. 2013;170(7):790-798<\/p>\n<p>Rodr\u00edguez-Ma\u00f1as L, F\u00e9art C, Mann G, Vi\u00f1a J, Chatterji S, Chodzko-Zajko W, Gonzalez-Cola\u00e7o Harmand M, Bergman H, Carcaillon L, Nicholson C, Scuteri A, Sinclair A, Pelaez M, Van der Cammen T, Beland F, Bickenbach J, Delamarche P, Ferrucci L, Fried LP, Guti\u00e9rrez-Robledo LM, Rockwood K, Rodr\u00edguez Artalejo F, Serviddio G, Vega E; FOD-CC group (Appendix 1). <strong>Searching for an operational definition of frailty: a Delphi method based consensus statement: the frailty operative definition-consensus conference project.<\/strong> J Gerontol A Biol Sci Med Sci. 2013;68(1):62-7. Epub 2012 Apr 16<\/p>\n<p>Ryan J, Carri\u00e8re I, Carcaillon L, Dartigues JF, Auriacombe S, Rouaud O, Berr C, Ritchie K, Scarabin PY, Ancelin ML.<strong>\u00a0Estrogen receptor polymorphisms and incident dementia: The prospective 3C study. Alzheimers Dement.<\/strong>\u00a02013 Mar 9. doi:pii: S1552-5260(13)00011-3. 10.1016\/j.jalz.2012.12.008. [Epub ahead of print]\n<p>Sachdev PS, Lipnicki DM, Kochan NA, Crawford JD, Rockwood K, Xiao S, Li J, Li X, Brayne C, Matthews FE, Stephan BC, Lipton RB, Katz MJ, Ritchie K, Carri\u00e8re I, Ancelin ML, Seshadri S, Au R, Beiser AS, Lam LC, Wong CH, Fung AW, Kim KW, Han JW, Kim TH, Petersen RC, Roberts RO, Mielke MM, Ganguli M, Dodge H, Hughes T, Anstey KJ, Cherbuin N, Butterworth P, Ng TP, Gao Q, Reppermund S, Brodaty H, Meguro K, Schupf N, Manly J, Stern Y, Lobo A, Lopez-Anton R, Santab\u00e1rbara J. <strong>COSMIC (Cohort Studies of Memory in an International Consortium): An international consortium to identify risk and protective factors and biomarkers of cognitive ageing and dementia in diverse ethnic and sociocultural groups.<\/strong> BMC Neurol. 2013;13(1):165<\/p>\n<p>Samieri C, Ginder Coupez V, Lorrain S, Letenneur L, All\u00e8s B, F\u00e9art C, Paineau D, Barberger-Gateau P.\u00a0<strong>Nutrient patterns and risk of fracture in older subjects: results from the Three-City Study.<\/strong> Osteoporos Int. 2013 Apr;24(4):1295-305<\/p>\n<p>Samieri C, Lorrain S, Buaud B, Vaysse C, Berr C, Peuchant E, Cunnane SC, Barberger-Gateau P. <strong>Relationship between diet and plasma long-chain n-3 PUFA in older people:Impact of Apolipoprotein E genotype. <\/strong>J Lipid Res. 2013;54(9):2559-67. Epub 2013 Jun 25<\/p>\n<p>Satizabal CL, Zhu YC, Dufouil C, Tzourio C.\u00a0<strong>Inflammatory Proteins and the Severity of Dilated Virchow-Robin Spaces in the Elderly.\u00a0<\/strong>J Alzheimers Dis. 2013;33(2):323-8<\/p>\n<p>Schilling S, Destefano AL, Sachdev PS, Choi SH, Mather KA, Decarli CD, Wen W, H\u00f8gh P, Raz N, Au R, Beiser A, Wolf PA, Romero JR, Zhu YC, Lunetta KL, Farrer L, Dufouil C, Kuller LH, Mazoyer B, Seshadri S, Tzourio C, Debette S. A<strong>POE genotype and MRI markers of cerebrovascular disease: Systematic review and meta-analysis.<\/strong> Neurology. 2013;81(3):292-300<\/p>\n<p>Soisson V, Brailly-Tabard S, Helmer C, Rouaud O, Ancelin ML, Zerhouni C, Guiochon-Mantel A, Scarabin PY. <strong>A J-shaped association between plasma testosterone and risk of ischemic arterial event in elderly men: The French 3C cohort study.<\/strong> Maturitas. 2013;75(3):282-8. doi: 10.1016\/j.maturitas.2013.04.012. Epub 2013 May 22<\/p>\n<p>Straczek C, Marti-Soler H, Tafflet M, Perier MC, Dupuy AM, Tzourio C, Barberger-Gateau P, Empana JP. <strong>Comparable incremental value of standard and nonstandard lipids for coronary heart disease risk assessment in elderly adults: the three city study.<\/strong> J Am Geriatr Soc. 2013;61(7):1234-6. doi: 10.1111\/jgs.12347<\/p>\n<p>Tang W, Teichert M, Chasman DI, Heit JA, Morange PE, Li G, Pankratz N, Leebeek FW, Par\u00e9 G, de Andrade M, Tzourio C, Psaty BM, Basu S, Ruiter R, Rose L, Armasu SM, Lumley T, Heckbert SR, Uitterlinden AG, Lathrop M, Rice KM, Cushman M, Hofman A, Lambert JC, Glazer NL, Pankow JS, Witteman JC, Amouyel P, Bis JC, Bovill EG, Kong X, Tracy RP, Boerwinkle E, Rotter JI, Tr\u00e9gou\u00ebt DA, Loth DW, Stricker BH, Ridker PM, Folsom AR, Smith NL.<strong>A Genome-Wide Association Study for Venous Thromboembolism: The Extended Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium.<\/strong> Genet Epidemiol. 2013;37(5):512-21. Epub 2013 May 5<\/div><\/div><\/div><\/div><\/div><style type=\"text\/css\">.fusion-accordian  #accordion-880-13 .panel-title a .fa-fusion-box{ color: #ffffff;}.fusion-accordian  #accordion-880-13 .panel-title a .fa-fusion-box:before{ font-size: 16px; width: 16px;}.fusion-accordian  #accordion-880-13 .panel-title a{font-size:24px;}.fusion-accordian  #accordion-880-13 .fa-fusion-box { background-color: #212934;border-color: #212934;}.fusion-accordian  #accordion-880-13 .panel-title a:hover, #accordion-880-13 .fusion-toggle-boxed-mode:hover .panel-title a { color: #65bc7b;}.fusion-accordian  #accordion-880-13 .panel-title .active .fa-fusion-box,.fusion-accordian  #accordion-880-13 .panel-title a:hover .fa-fusion-box { background-color: #65bc7b!important;border-color: #65bc7b!important;}<\/style><div class=\"accordian fusion-accordian\"><div class=\"panel-group\" id=\"accordion-880-13\"><div class=\"fusion-panel panel-default\"><div class=\"panel-heading\"><h4 class=\"panel-title toggle\"><a aria-expanded=\"false\" aria-controls=\"b60a30ebedcba4588\" role=\"button\" data-toggle=\"collapse\" data-parent=\"#accordion-880-13\" data-target=\"#b60a30ebedcba4588\" href=\"#b60a30ebedcba4588\"><span class=\"fusion-toggle-icon-wrapper\" aria-hidden=\"true\"><i class=\"fa-fusion-box\" aria-hidden=\"true\"><\/i><\/span><span class=\"fusion-toggle-heading\">2014<\/span><\/a><\/h4><\/div><div id=\"b60a30ebedcba4588\" class=\"panel-collapse collapse \"><div class=\"panel-body toggle-content fusion-clearfix\">\n<p>Alp\u00e9rovitch A, Blachier M, Soumar\u00e9 A, Ritchie K, Dartigues JF, Richard-Harston S, Tzourio C. <strong>Blood pressure variability and risk of dementia in an elderly cohort, the Three-City Study.<\/strong> Alzheimers Dement. 2014;10(5 Suppl):S330-7. Epub 2013 Aug 15<\/p>\n<p>Avila-Funes JA, Meillon C, Gonz\u00e1lez-Cola\u00e7o Harmand M, Tzourio C, Dartigues JF, Amieva H. <strong>Association between frailty and carotid central structure changes: the Three-City Study.<\/strong> J Am Geriatr Soc. 2014;62(10):1906-11. Epub 2014 Oct 3.<\/p>\n<p>Ancelin ML, Ripoche E, Dupuy AM, Samieri C, Rouaud O, Berr C, Carri\u00e8re I, Ritchie K. <strong>Gender-specific associations between lipids and cognitive decline in the elderly.<\/strong> Eur Neuropsychopharmacol. 2014;24(7):1056-66. Epub 2014 Feb 17<\/p>\n<p>Asayama K, Thijs L, Brguljan-Hitij J, Niiranen TJ, Hozawa A, Boggia J, Aparicio LS, Hara A, Johansson JK, Ohkubo T, Tzourio C, Stergiou GS, Sandoya E, Tsuji I, Jula AM, Imai Y, Staessen JA; International Database of Home Blood Pressure in Relation to Cardiovascular Outcome (IDHOCO) investigators. <strong>Risk stratification by self-measured home blood pressure across categories of conventional blood pressure: a participant-level meta-analysis.<\/strong> PLoS Med. 2014;11(1):e1001591. Epub 2014 Jan 21<\/p>\n<p>Barberger-Gateau P. <strong>Nutrition and brain aging: how can we move ahead?<\/strong> Eur J Clin Nutr. 2014;68(11):1245-9. Epub 2014 Aug 27.<\/p>\n<p>Benitez BA, Jin SC, Guerreiro R, Graham R, Lord J, Harold D, Sims R, Lambert JC, Gibbs JR, Bras J, Sassi C, Harari O, Bertelsen S, Lupton MK, Powell J, Bellenguez C, Brown K, Medway C, Haddick PC, van der Brug MP, Bhangale T, Ortmann W, Behrens T, Mayeux R, Pericak-Vance MA, Farrer LA, Schellenberg GD, Haines JL, Turton J, Braae A, Barber I, Fagan AM, Holtzman DM, Morris JC; 3C Study Group; EADI consortium; Alzheimer&rsquo;s Disease Genetic Consortium (ADGC); Alzheimer&rsquo;s Disease Neuroimaging Initiative (ADNI); GERAD Consortium, Williams J, Kauwe JS, Amouyel P, Morgan K, Singleton A, Hardy J, Goate AM, Cruchaga C. <strong>Missense variant in TREML2 protects against Alzheimer&rsquo;s disease.<\/strong> Neurobiol Aging. 2014;35(6):1510.e19-26. Epub 2013 Dec 21<\/p>\n<p>Bernard C, Helmer C, Dilharreguy B, Amieva H, Auriacombe S, Dartigues JF, Allard M, Catheline G. <strong>Time course of brain volume changes in the preclinical phase of Alzheimer&rsquo;s disease.<\/strong> Alzheimers Dement. 2014;10(2):143-151.e1.Epub 2014 Jan 10<\/p>\n<p>Brickman AM, Schupf N, Manly JJ, Stern Y, Luchsinger JA, Provenzano FA, Narkhede A, Razlighi Q, Collins-Praino L, Artero S, Akbaraly TN, Ritchie K, Mayeux R, Portet F. <strong>APOE \u03b54 and risk for Alzheimer&rsquo;s disease: do regionally distributed white matter hyperintensities play a role?<\/strong> Alzheimers Dement. 2014;10(6):619-29. Epub 2014 Oct<\/p>\n<p>Carcaillon L, Brailly-Tabard S, Ancelin ML, Rouaud O, Dartigues JF, Guiochon-Mantel A, Scarabin PY. <strong>High plasma estradiol interacts with diabetes on risk of dementia in older postmenopausal women.<\/strong> Neurology. 2014;82(6):504-11.Epub 2014 Jan 29<\/p>\n<p>Carcaillon L, Brailly-Tabard S, Ancelin ML, Tzourio C, Foubert-Samier A, Dartigues JF, Guiochon-Mantel A, Scarabin PY. <strong>Low testosterone and the risk of dementia in elderly men: Impact of age and education.<\/strong> Alzheimers Dement. 2014;10(5 Suppl):S306-14. Epub 2013 Sep 10.<\/p>\n<p>Carriere I, P\u00e9r\u00e8s K, Ancelin ML, Gourlet V, Berr C, Barberger-Gateau P, Bouillon K, Kivimaki M, Ritchie K, Akbaraly T. <strong>Metabolic Syndrome and Disability: Findings From the Prospective Three-City Study.<\/strong> J Gerontol A Biol Sci Med Sci. 2014;69(1):79-86. Epub 2013 Jul 5<\/p>\n<p>Chouraki V, De Bruijn RF, Chapuis J, Bis JC, Reitz C, Schraen S, Ibrahim-Verbaas CA, Grenier-Boley B, Delay C, Rogers R, Demiautte F, Mounier A, Fitzpatrick AL; The Alzheimer&rsquo;s Disease Neuroimaging Initiative, Berr C, Dartigues JF, Uitterlinden AG, Hofman A, Breteler M, Becker JT, Lathrop M, Schupf N, Alp\u00e9rovitch A, Mayeux R, van Duijn CM, Bu\u00e9e L, Amouyel P, Lopez OL, Ikram MA, Tzourio C, Lambert JC. <strong>A genome-wide association meta-analysis of plasma A\u03b2 peptides concentrations in the elderly.<\/strong> Mol Psychiatry. 2014;19(12):1326-35. Epub 2014 Feb 18.<\/p>\n<p>Cougnard-Gr\u00e9goire A, Delyfer MN, Korobelnik JF, Rougier MB, Le Goff M, Dartigues JF, Barberger-Gateau P, Delcourt C. <strong>Elevated high-density lipoprotein cholesterol and age-related macular degeneration: the Alienor study.<\/strong> PLoS One. 2014;9(3):e90973<\/p>\n<p>Crivello F, Tzourio-Mazoyer N, Tzourio C, Mazoyer B. <strong>Longitudinal assessment of global and regional rate of grey matter atrophy in 1,172 healthy older adults: modulation by sex and age.<\/strong> PLoS One. 2014; 9(12):e114478.<\/p>\n<p>Cyprien F, Courtet P, Poulain V, Maller J, Meslin C, Bonaf\u00e9 A, Le Bars E, Ancelin ML, Ritchie K, Artero S. <strong>Corpus callosum size may predict late-life depression in women: A 10-year follow-up study.<\/strong> J Affect Disord. 2014;165:16-23. Epub 2014 Apr 24<\/p>\n<p>Debette S, Wolf C, Lambert JC, Crivello F, Soumar\u00e9 A, Zhu YC, Schilling S, Dufouil C, Mazoyer B, Amouyel P, Tzourio C, Elbaz A. <strong>Abdominal obesity and lower gray matter volume: a Mendelian randomization study.<\/strong> Neurobiol Aging. 2014;35(2):378-86. Epub 2013 Aug 31<\/p>\n<p>Delcourt C, Cougnard-Gr\u00e9goire A, Boniol M, Carri\u00e8re I, Dor\u00e9 JF, Delyfer MN, Rougier MB, Le Goff M, Dartigues JF, Barberger-Gateau P, Korobelnik JF. <strong>Lifetime exposure to ambient ultraviolet radiation and the risk for cataract extraction and age-related macular degeneration: the Alienor Study.<\/strong> Invest Ophthalmol Vis Sci. 2014;55(11):7619-27<\/p>\n<p>Delva F, Edjolo A, P\u00e9r\u00e8s K, Berr C, Barberger-Gateau P, Dartigues JF. <strong>Hierarchical structure of the activities of daily living scale in dementia.<\/strong> J Nutr Health Aging. 2014;18(7):698-704<\/p>\n<p>Dong J, Gao J, Nalls M, Gao X, Huang X, Han J, Singleton AB, Chen H; International Parkinson&rsquo;s Disease Genomics Consortium (IPDGC). <strong>Susceptibility loci for pigmentation and melanoma in relation to Parkinson&rsquo;s disease.<\/strong> Neurobiol Aging. 2014;35(6):1512.e5-10. Epub 2013 Dec 27.<\/p>\n<p>Dumurgier J, Singh-Manoux A, Tavernier B, Tzourio C, Elbaz A. <strong>Lipid-Lowering Drugs Associated With Slower Motor Decline in the Elderly Adults.<\/strong> J Gerontol A Biol Sci Med Sci. 2014;69(2):199-206. Epub 2013 Oct 4<\/p>\n<p>Elbejjani M, Fuhrer R, Abrahamowicz M, Mazoyer B, Crivello F, Tzourio C, Dufouil C. <strong>Hippocampal atrophy and subsequent depressive symptoms in older men and women: results from a 10-year prospective cohort. Am J Epidemiol.<\/strong> 2014;180(4):385-93. Epub 2014 Aug 1<\/p>\n<p>Escott-Price V, Bellenguez C, Wang LS, Choi SH, Harold D, Jones L, Holmans P, Gerrish A, Vedernikov A, Richards A, DeStefano AL, Lambert JC, Ibrahim-Verbaas CA, Naj AC, Sims R, Jun G, Bis JC, Beecham GW, Grenier-Boley B, Russo G, Thornton-Wells TA, Denning N, Smith AV, Chouraki V, Thomas C, Ikram MA, Zelenika D, Vardarajan BN, Kamatani Y, Lin CF, Schmidt H, Kunkle B, Dunstan ML, Vronskaya M; United Kingdom Brain Expression Consortium, Johnson AD, Ruiz A, Bihoreau MT, Reitz C, Pasquier F, Hollingworth P, Hanon O, Fitzpatrick AL, Buxbaum JD, Campion D, Crane PK, Baldwin C, Becker T, Gudnason V, Cruchaga C, Craig D, Amin N, Berr C, Lopez OL, De Jager PL, Deramecourt V, Johnston JA, Evans D, Lovestone S, Letenneur L, Hern\u00e1ndez I, Rubinsztein DC, Eiriksdottir G, Sleegers K, Goate AM, Fi\u00e9vet N, Huentelman MJ, Gill M, Brown K, Kamboh MI, Keller L, Barberger-Gateau P, McGuinness B, Larson EB, Myers AJ, Dufouil C, Todd S, Wallon D, Love S, Rogaeva E, Gallacher J, George-Hyslop PS, Clarimon J, Lleo A, Bayer A, Tsuang DW, Yu L, Tsolaki M, Boss\u00f9 P, Spalletta G, Proitsi P, Collinge J, Sorbi S, Garcia FS, Fox NC, Hardy J, Naranjo MC, Bosco P, Clarke R, Brayne C, Galimberti D, Scarpini E, Bonuccelli U, Mancuso M, Siciliano G, Moebus S, Mecocci P, Zompo MD, Maier W, Hampel H, Pilotto A, Frank-Garc\u00eda A, Panza F, Solfrizzi V, Caffarra P, Nacmias B, Perry W, Mayhaus M, Lannfelt L, Hakonarson H, Pichler S, Carrasquillo MM, Ingelsson M, Beekly D, Alvarez V, Zou F, Valladares O, Younkin SG, Coto E, Hamilton-Nelson KL, Gu W, Razquin C, Pastor P, Mateo I, Owen MJ, Faber KM, Jonsson PV, Combarros O, O&rsquo;Donovan MC, Cantwell LB, Soininen H, Blacker D, Mead S, Mosley TH Jr, Bennett DA, Harris TB, Fratiglioni L, Holmes C, de Bruijn RF, Passmore P, Montine TJ, Bettens K, Rotter JI, Brice A, Morgan K, Foroud TM, Kukull WA, Hannequin D, Powell JF, Nalls MA, Ritchie K, Lunetta KL, Kauwe JS, Boerwinkle E, Riemenschneider M, Boada M, Hiltunen M, Martin ER, Schmidt R, Rujescu D, Dartigues JF, Mayeux R, Tzourio C, Hofman A, N\u00f6then MM, Graff C, Psaty BM, Haines JL, Lathrop M, Pericak-Vance MA, Launer LJ, Van Broeckhoven C, Farrer LA, van Duijn CM, Ramirez A, Seshadri S, Schellenberg GD, Amouyel P, Williams J. <strong>Gene-wide analysis detects two new susceptibility genes for Alzheimer&rsquo;s disease.<\/strong> PLoS One. 2014;9(6):e94661<\/p>\n<p>Global Burden of Metabolic Risk Factors for Chronic Diseases Collaboration. <strong>Cardiovascular disease, chronic kidney disease, and diabetes mortality burden of cardiometabolic risk factors from 1980 to 2010: a comparative risk assessment.Lancet Diabetes Endocrinol.<\/strong> 2014;2(8):634-47. Epub 2014 May 16<\/p>\n<p>Gusareva ES, Carrasquillo MM, Bellenguez C, Cuyvers E, Colon S, Graff-Radford NR, Petersen RC, Dickson DW, Mahachie John JM, Bessonov K, Van Broeckhoven C; the GERAD1 Consortium, Harold D, Williams J, Amouyel P, Sleegers K, Ertekin-Taner N, Lambert JC, Van Steen K.<strong> Genome-wide association interaction analysis for Alzheimer&rsquo;s disease.<\/strong> Neurobiol Aging. 2014;35(11):2436-43. Epub 2014 May 28<\/p>\n<p>Herbert A, Cruickshank JK, Laurent S, Boutouyrie P; on behalf of The Reference Values for Arterial Measurements Collaboration; on behalf of The Reference Values for Arterial Measurements Collaboration. <strong>Establishing reference values for central blood pressure and its amplification in a general healthy population and according to cardiovascular risk factors.<\/strong> Eur Heart J. 2014;35(44):3122-33. Epub 2014 Aug 11<\/p>\n<p>Hysi PG, Cheng CY, Springelkamp H, Macgregor S, Bailey JN, Wojciechowski R, Vitart V, Nag A, Hewitt AW, H\u00f6hn R, Venturini C, Mirshahi A, Ramdas WD, Thorleifsson G, Vithana E, Khor CC, Stefansson AB, Liao J, Haines JL, Amin N, Wang YX, Wild PS, Ozel AB, Li JZ, Fleck BW, Zeller T, Staffieri SE, Teo YY, Cuellar-Partida G, Luo X, Allingham RR, Richards JE, Senft A, Karssen LC, Zheng Y, Bellenguez C, Xu L, Iglesias AI, Wilson JF, Kang JH, van Leeuwen EM, Jonsson V, Thorsteinsdottir U, Despriet DD, Ennis S, Moroi SE, Martin NG, Jansonius NM, Yazar S, Tai ES, Amouyel P, Kirwan J, van Koolwijk LM, Hauser MA, Jonasson F, Leo P, Loomis SJ, Fogarty R, Rivadeneira F, Kearns L, Lackner KJ, de Jong PT, Simpson CL, Pennell CE, Oostra BA, Uitterlinden AG, Saw SM, Lotery AJ, Bailey-Wilson JE, Hofman A, Vingerling JR, Maubaret C, Pfeiffer N, Wolfs RC, Lemij HG, Young TL, Pasquale LR, Delcourt C, Spector TD, Klaver CC, Small KS, Burdon KP, Stefansson K, Wong TY; BMES GWAS Group; NEIGHBORHOOD Consortium; Wellcome Trust Case Control Consortium 2, Viswanathan A, Mackey DA, Craig JE, Wiggs JL, van Duijn CM, Hammond CJ, Aung T. <strong>Genome-wide analysis of multi-ancestry cohorts identifies new loci influencing intraocular pressure and susceptibility to glaucoma. <\/strong>Nat Genet. 2014;46(10):1126-30. Epub 2014 Aug 31<\/p>\n<p>Kaffashian S, Tzourio C, Soumar\u00e9 A, Dufouil C, Zhu Y, Crivello F, Maillard P, Schraen-Maschke S, Mazoyer B, Bu\u00e9e L, Debette S. <strong>Plasma \u03b2-amyloid and MRI markers of cerebral small vessel disease: Three-City Dijon study. <\/strong>Neurology. 2014;83(22):2038-45. Epub 2014 Oct 29<\/p>\n<p>Malet F, Le Goff M, Colin J, Schweitzer C, Delyfer MN, Korobelnik JF, Rougier MB, Radeau T, Dartigues JF, Delcourt C. <strong>Dry eye disease in French elderly subjects: the Alienor Study.<\/strong> Acta Ophthalmol. 2014;92(6):e429-36. Epub 2013 Jun 7<\/p>\n<p>Marie Dit Asse L, Fabrigoule C, Helmer C, Laumon B, Lafont S. <strong>Automobile driving in older adults: factors affecting driving restriction in men and women.<\/strong> J Am Geriatr Soc. 2014;62(11):2071-8<\/p>\n<p>Mortamais M, Portet F, Brickman AM, Provenzano FA, Muraskin J, Akbaraly TN, Berr C, Touchon J, Bonaf\u00e9 A, le Bars E, Menjot de Champfleur N, Maller JJ, Meslin C, Sabatier R, Ritchie K, Artero S. <strong>Education Modulates the Impact of White Matter Lesions on the Risk of Mild Cognitive Impairment and Dementia.<\/strong> Am J Geriatr Psychiatry. 2014;22(11):1336-45. Epub 2013 Sep 8.<\/p>\n<p>Nalls MA, Saad M, Noyce AJ, Keller MF, Schrag A, Bestwick JP, Traynor BJ, Gibbs JR, Hernandez DG, Cookson MR, Morris HR, Williams N, Gasser T, Heutink P, Wood N, Hardy J, Martinez M, Singleton AB; International Parkinson&rsquo;s Disease Genomics Consortium (IPDGC); Wellcome Trust Case Control Consortium 2 (WTCCC2); North American Brain Expression Consortium (NABEC); United Kingdom Brain Expression Consortium (UKBEC). <strong>Genetic comorbidities in Parkinson&rsquo;s disease.<\/strong> Hum Mol Genet. 2014;23(3):831-41.Epub 2013 Sep 20<\/p>\n<p>Philipps V, Amieva H, Andrieu S, Dufouil C, Berr C, Dartigues JF, Jacqmin-Gadda H, Proust-Lima C. <strong>Normalized Mini-Mental State Examination for Assessing Cognitive Change in Population-Based Brain Aging Studies. Neuroepidemiology.<\/strong> 2014;43(1):15-25. Epub 2014 Sep 18<\/p>\n<p>Rocanin-Arjo A, Cohen W, Carcaillon L, Fr\u00e8re C, Saut N, Letenneur L, Alhenc-Gelas M, Dupuy AM, Bertrand M, Alessi MC, Germain M, Wild PS, Zeller T, Cambien F, Goodall AH, Amouyel P, Scarabin PY, Tr\u00e9gou\u00ebt DA, Morange PE; CardioGenics Consortium. <strong>A meta-analysis of genome-wide association studies identifies ORM1 as a novel gene controlling thrombin generation potential.<\/strong> Blood. 2014;123(5):777-85. Epub 2013 Dec 19<\/p>\n<p>Rist PM, Tzourio C, Elbaz A, Soumar\u00e9 A, Dufouil C, Mazoyer B, Kurth T. <strong>Structural brain lesions and restless legs syndrome: a cross-sectional population-based study.<\/strong> BMJ Open. 2014;4(11):e005938. doi: 10.1136\/bmjopen-2014-005938.<\/p>\n<p>Ritchie K, Ancelin ML, Amieva H, Rouaud O, Carri\u00e8re I. <strong>The association between caffeine and cognitive decline: examining alternative causal hypotheses.<\/strong> Int Psychogeriatr. 2014;26(4):581-90. Epub 2014 Jan 15<\/p>\n<p>Ryan J, Artero S, Carri\u00e8re I, Scali J, Maller JJ, Meslin C, Ritchie K, Scarabin PY, Ancelin ML. <strong>Brain volumes in late life: gender, hormone treatment, and estrogen receptor variants. <\/strong>Neurobiol Aging. 2014;35(3):645-54. Epub 2013 Oct 23<\/p>\n<p>Ryan J, Carri\u00e8re I, Carcaillon L, Dartigues JF, Auriacombe S, Rouaud O, Berr C, Ritchie K, Scarabin PY, Ancelin ML. <strong>Estrogen receptor polymorphisms and incident dementia: the prospective 3C study.<\/strong> Alzheimers Dement. 2014;10(1):27-35<\/p>\n<p>Ryan J, Scali J, Carri\u00e8re I, Amieva H, Rouaud O, Berr C, Ritchie K, Ancelin ML.Impact of a premature menopause on cognitive function in later life. BJOG. 2014;121(13):1729-39. Epub 2014 May 7<\/p>\n<p>Sabia S, Dumurgier J, Tavernier B, Head J, Tzourio C, Elbaz A. <strong>Change in walking speed preceding death: results from a prospective longitudinal cohort study.<\/strong> J Gerontol A Biol Sci Med Sci 2014;69(3):354-62. Epub 2013 Aug 2<\/p>\n<p>Scarabin-Carr\u00e9 V, Brailly-Tabard S, Ancelin ML, Maubaret C, Guiochon-Mantel A, Canonico M, Scarabin PY. <strong>Plasma estrogen levels, estrogen receptor gene variation and ischemic arterial disease in postmenopausal women: the Three-City prospective Cohort Study.<\/strong> J Clin Endocrinol Metab. 2014;99(8):E1539-46. doi: 10.1210\/jc.2013-4472. Epub 2014 May 13<\/p>\n<p>Schilling S, Tzourio C, Dufouil C, Zhu Y, Berr C, Alp\u00e9rovitch A, Crivello F, Mazoyer B, Debette S. <strong>Plasma lipids and cerebral small vessel disease. Neurology.<\/strong> 2014;83(20):1844-52. Epub 2014 Oct 15.<\/p>\n<p>Singh B, Parsaik AK, Mielke MM, Erwin PJ, Knopman DS, Petersen RC, Roberts RO. <strong>Association of mediterranean diet with mild cognitive impairment and Alzheimer&rsquo;s disease: a systematic review and meta-analysis.<\/strong> J Alzheimers Dis. 2014;39(2):271-82. Review.<\/p>\n<p>Seidowsky A, Massy ZA, Metzger M, Stengel B. <strong>Resistant hypertension and chronic kidney disease: epidemiology and prognosis.<\/strong>Nephrol Ther. 2014;10(3):137-44. Epub 2014 Apr 13. French.<\/p>\n<p>Torres MJ, Dorigny B, Kuhn M, Berr C, Barberger-Gateau P, Letenneur L. <strong>Nutritional status in community-dwelling elderly in france in urban and rural areas.<\/strong> PLoS One. 2014;9(8):e105137<\/p>\n<p>Tzourio C, Laurent S, Debette S. <strong>Is hypertension associated with an accelerated aging of the brain?<\/strong> Hypertension. 2014;63(5):894-903. Epub 2014 Feb 24<\/p>\n<p>Yao M, Zhu YC, Soumar\u00e9 A, Dufouil C, Mazoyer B, Tzourio C, Chabriat H. <strong>Hippocampal perivascular spaces are related to aging and blood pressure but not to cognition.<\/strong> Neurobiol Aging. 2014;35(9):2118-25. Epub 2014 Mar 22<\/p>\n<\/div><\/div><\/div><\/div><\/div><style type=\"text\/css\">.fusion-accordian  #accordion-880-14 .panel-title a .fa-fusion-box{ color: #ffffff;}.fusion-accordian  #accordion-880-14 .panel-title a .fa-fusion-box:before{ font-size: 16px; width: 16px;}.fusion-accordian  #accordion-880-14 .panel-title a{font-size:24px;}.fusion-accordian  #accordion-880-14 .fa-fusion-box { background-color: #212934;border-color: #212934;}.fusion-accordian  #accordion-880-14 .panel-title a:hover, #accordion-880-14 .fusion-toggle-boxed-mode:hover .panel-title a { color: #65bc7b;}.fusion-accordian  #accordion-880-14 .panel-title .active .fa-fusion-box,.fusion-accordian  #accordion-880-14 .panel-title a:hover .fa-fusion-box { background-color: #65bc7b!important;border-color: #65bc7b!important;}<\/style><div class=\"accordian fusion-accordian\"><div class=\"panel-group\" id=\"accordion-880-14\"><div class=\"fusion-panel panel-default\"><div class=\"panel-heading\"><h4 class=\"panel-title toggle\"><a aria-expanded=\"false\" aria-controls=\"cc33c8bc78b607923\" role=\"button\" data-toggle=\"collapse\" data-parent=\"#accordion-880-14\" data-target=\"#cc33c8bc78b607923\" href=\"#cc33c8bc78b607923\"><span class=\"fusion-toggle-icon-wrapper\" aria-hidden=\"true\"><i class=\"fa-fusion-box\" aria-hidden=\"true\"><\/i><\/span><span class=\"fusion-toggle-heading\">2015<\/span><\/a><\/h4><\/div><div id=\"cc33c8bc78b607923\" class=\"panel-collapse collapse \"><div class=\"panel-body toggle-content fusion-clearfix\">\n<p>Akbaraly TN, Jaussent I, Besset A, Bertrand M, Barberger-Gateau P, Ritchie K, Ferrie JE, Kivimaki M, Dauvilliers Y. <strong>Sleep Complaints and Metabolic Syndrome in an Elderly Population: The Three-City Study.<\/strong> Am J Geriatr Psychiatry. 2015;23(8):818-28. Epub 2014 Oct 15 4.2<\/p>\n<p>Alp\u00e9rovitch A, Kurth T, Bertrand M, Ancelin ML, Helmer C, Debette S, Tzourio C.<strong> Primary prevention with lipid lowering drugs and long term risk of vascular events in older people: population based cohort study.<\/strong> BMJ. 2015 May 19;350:h2335. doi: 10.1136\/bmj.h2335 17.4<\/p>\n<p>Ancelin ML, Farr\u00e9 A, Carri\u00e8re I, Ritchie K, Chaudieu I, Ryan J. <strong>C-reactive protein gene variants: independent association with late-life depression and circulating protein levels.<\/strong> Transl Psychiatry. 2015 Jan 20;5:e499. doi: 10.1038\/tp.2014.145 4.4<\/p>\n<p>Artaud F, Singh-Manoux A, Dugravot A, Tzourio C, Elbaz A. <strong>Decline in Fast Gait Speed as a Predictor of Disability in Older Adults. <\/strong>J Am Geriatr Soc. 2015;63(6):1129-36. Epub 2015 Jun 11 4.6<\/p>\n<p>Bernard C, Dilharreguy B, Helmer C, Chanraud S, Amieva H, Dartigues JF, Allard M, Catheline G. <strong>PCC characteristics at rest in 10-year memory decliners.<\/strong> Neurobiol Aging. 2015;36(10):2812-20. Epub 2015 Jul 9. 5.0<\/p>\n<p>Blanche P, Proust-Lima C, Loub\u00e8re L, Berr C, Dartigues JF, Jacqmin-Gadda H. <strong>Quantifying and comparing dynamic predictive accuracy of joint models for longitudinal marker and time-to-event in presence of censoring and competing risks.<\/strong> Biometrics. 2015;71(1):102-13. Epub 2014 Oct 13. 1.6<\/p>\n<p>Bousquet J, Anto JM, Berkouk K, Gergen P, Pinto Antunes J, Aug\u00e9 P, Camuzat T, Bringer J, Mercier J, Best N, Bourret R, Akdis M, Arshad SH, Bedbrook A, Berr C, Bush A, Cavalli G, Charles MA, Clavel-Chapelon F, Gillman M, Gold DR, Goldberg M, Holloway JW, Iozzo P, Jacquemin S, Jeandel C, Kauffmann F, Keil T, Koppelman GH, Krauss-Etschmann S, Kuh D, Lehmann S, Lodrup Carlsen KC, Maier D, M\u00e9chali M, Mel\u00e9n E, Moatti JP, Momas I, N\u00e9rin P, Postma DS, Ritchie K, Robine JM, Samolinski B, Siroux V, Slagboom PE, Smit HA, Sunyer J, Valenta R, Van de Perre P, Verdier JM, Vrijheid M, Wickman M, Yiallouros P, Zins M. <strong>Developmental determinants in non-communicable chronic diseases and ageing.<\/strong> Thorax. 2015;70(6):595-7. Epub 2015 Jan 23. 8.6<\/p>\n<p>Br\u00fcck K, Jager KJ, Dounousi E, Kainz A, Nitsch D, \u00c4rnl\u00f6v J, Rothenbacher D, Browne G, Capuano V, Ferraro PM, Ferrieres J, Gambaro G, Guessous I, Hallan S, Kastarinen M, Navis G, Gonzalez AO, Palmieri L, Romundstad S, Spoto B, Stengel B, Tomson C, Tripepi G, V\u00f6lzke H, Wi\u0229cek A, Gansevoort R, Sch\u00f6ttker B, Wanner C, Vinhas J, Zoccali C, Van Biesen W, Stel VS; European CKD Burden Consortium. <strong>Methodology used in studies reporting chronic kidney disease prevalence: a systematic literature review.<\/strong> Nephrol Dial Transplant. 2015;30 Suppl 4:iv6-16. 3.6<\/p>\n<p>Carcaillon L, Plichart M, Zureik M, Rouaud O, Majed B, Ritchie K, Tzourio C, Dartigues JF, Empana JP. <strong>Carotid plaque as a predictor of dementia in older adults: the Three-City Study.<\/strong> Alzheimers Dement. 2015;11(3):239-48. Epub 2014 Dec 12 12.4<\/p>\n<p>Carri\u00e8re I, Mura T, P\u00e9r\u00e8s K, Norton J, Jaussent I, Edjolo A, Rouaud O, Berr C, Ritchie K, Ancelin ML. <strong>Elderly Benzodiazepine Users at Increased Risk of Activity Limitations: Influence of Chronicity, Indications, and Duration of Action-The Three-City Cohort.<\/strong> Am J Geriatr Psychiatry. 2015;23(8):840-51. Epub 2014 Nov 6 4.2<\/p>\n<p>Catheline G, Amieva H, Dilharreguy B, Bernard C, Duperron MG, Helmer C, Dartigues JF, Allard M. <strong>Semantic retrieval over time in the aging brain: Structural evidence of hippocampal contribution.<\/strong> Hippocampus. 2015;25(9):1008-16. Epub 2015 Mar 25 4.2<\/p>\n<p>Charroud C, Steffener J, Bars EL, Deverdun J, Bonafe A, Abdennour M, Portet F, Molino F, Stern Y, Ritchie K, Champfleur NM, Akbaraly TN. <strong>Working memory activation of neural networks in the elderly as a function of information processing phase and task complexity.<\/strong> Neurobiol Learn Mem. 2015; 125:211-23. Epub 2015 Oct 8 3.6<\/p>\n<p>Chauhan G, Adams HH, Bis JC, Weinstein G, Yu L, T\u00f6glhofer AM, Smith AV, J van der Lee S, Gottesman RF, Thomson R, Wang J, Yang Q, Niessen WJ, Lopez OL, Becker JT, Phan TG, Beare RJ, Arfanakis K, Fleischman D, Vernooij MW, Mazoyer B, Schmidt H, Srikanth V, Knopman DS, Jack CR Jr, Amouyel P, Hofman A, DeCarli C, Tzourio C, van Duijn CM, Bennett DA, Schmidt R, Longstreth WT Jr, Mosley TH, Fornage M, Launer LJ, Seshadri S, Ikram MA, Debette S.<strong> Association of Alzheimer&rsquo;s disease GWAS loci with MRI markers of brain aging.<\/strong> Neurobiol Aging. 2015;36(4):1765.e7-16. Epub 2015 Jan 6 5.0<\/p>\n<p>Cougnard-Gr\u00e9goire A, Merle BM, Korobelnik JF, Rougier MB, Delyfer MN, F\u00e9art C, Le Goff M, Dartigues JF, Barberger-Gateau P, Delcourt C. <strong>Vitamin D Deficiency in Community-Dwelling Elderly Is Not Associated with Age-Related Macular Degeneration.<\/strong> J Nutr. 2015;145(8):1865-72. 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Epub 2015 Apr 11. 4.2<\/p>\n<p>Verhaaren BF, Debette S, Bis JC, Smith JA, Ikram MK, Adams HH, Beecham AH, Rajan KB, Lopez LM, Barral S, van Buchem MA, van der Grond J, Smith AV, Hegenscheid K, Aggarwal NT, de Andrade M, Atkinson EJ, Beekman M, Beiser AS, Blanton SH, Boerwinkle E, Brickman AM, Bryan RN, Chauhan G, Chen CP, Chouraki V, de Craen AJ, Crivello F, Deary IJ, Deelen J, De Jager PL, Dufouil C, Elkind MS, Evans DA, Freudenberger P, Gottesman RF, Gu\u00f0nason V, Habes M, Heckbert SR, Heiss G, Hilal S, Hofer E, Hofman A, Ibrahim-Verbaas CA, Knopman DS, Lewis CE, Liao J, Liewald DC, Luciano M, van der Lugt A, Martinez OO, Mayeux R, Mazoyer B, Nalls MA, Nauck M, Niessen WJ, Oostra BA, Psaty BM, Rice KM, Rotter JI, von Sarnowski B, Schmidt H, Schreiner PJ, Schuur M, Sidney SS, Sigurdsson S, Slagboom PE, Stott DJ, van Swieten JC, Teumer A, T\u00f6glhofer AM, Traylor M, Trompet S, Turner ST, Tzourio C, Uh HW, Uitterlinden AG, Vernooij MW, Wang JJ, Wong TY, Wardlaw JM, Windham BG, Wittfeld K, Wolf C, Wright CB, Yang Q, Zhao W, Zijdenbos A, Jukema JW, Sacco RL, Kardia SL, Amouyel P, Mosley TH, Longstreth WT Jr, DeCarli CC, van Duijn CM, Schmidt R, Launer LJ, Grabe HJ, Seshadri SS, Ikram MA, Fornage M. <strong>Multi-Ethnic Genome-Wide Association Study of Cerebral White Matter Hyperintensities on MRI.<\/strong> Circ Cardiovasc Genet. 2015;8(2):398-409. Epub 2015 Feb 7. 5.3<\/p>\n<p>Vivot A, Glymour MM, Tzourio C, Amouyel P, Ch\u00eane G, Dufouil C. <strong>Association of Alzheimer&rsquo;s related genotypes with cognitive decline in multiple domains: results from the Three-City Dijon study.<\/strong> Mol Psychiatry. 2015;20(10):1173-8. Epub 2015 Jun 2. 14.5<\/p>\n<p>Williams KM, Verhoeven VJ, Cumberland P, Bertelsen G, Wolfram C, Buitendijk GH, Hofman A, van Duijn CM, Vingerling JR, Kuijpers RW, H\u00f6hn R, Mirshahi A, Khawaja AP, Luben RN, Erke MG, von Hanno T, Mahroo O, Hogg R, Gieger C, Cougnard-Gr\u00e9goire A, Anastasopoulos E, Bron A, Dartigues JF, Korobelnik JF, Creuzot-Garcher C, Topouzis F, Delcourt C, Rahi J, Meitinger T, Fletcher A, Foster PJ, Pfeiffer N, Klaver CC, Hammond CJ. <strong>Prevalence of refractive error in Europe: the European Eye Epidemiology (E3) Consortium.<\/strong> Eur J Epidemiol. 2015;30(4):305-15. Epub 2015 Mar 18. 5.1<\/p>\n<p>Williams KM, Bertelsen G, Cumberland P, Wolfram C, Verhoeven VJ, Anastasopoulos E, Buitendijk GH, Cougnard-Gr\u00e9goire A, Creuzot-Garcher C, Erke MG, Hogg R, H\u00f6hn R, Hysi P, Khawaja AP, Korobelnik JF, Ried J, Vingerling JR, Bron A, Dartigues JF, Fletcher A, Hofman A, Kuijpers RW, Luben RN, Oxele K, Topouzis F, von Hanno T, Mirshahi A, Foster PJ, van Duijn CM, Pfeiffer N, Delcourt C, Klaver CC, Rahi J, Hammond CJ; European Eye Epidemiology (E(3)) Consortium. <strong>Increasing Prevalence of Myopia in Europe and the Impact of Education.<\/strong> Ophthalmology. 2015;122(7):1489-97. Epub 2015 May 13 6.1<\/p>\n<p>Zhang X, Norton J, Carri\u00e8re I, Ritchie K, Chaudieu I, Ancelin ML. <strong>Risk factors for late-onset generalized anxiety disorder: results from a 12-year prospective cohort (the ESPRIT study).<\/strong> Transl Psychiatry. 2015 Mar 31;5:e536. doi: 10.1038\/tp.2015.31 5.6<\/p>\n<p>Zhang X, Norton J, Carri\u00e8re I, Ritchie K, Chaudieu I, Ancelin ML. <strong>Generalized anxiety in community-dwelling elderly: Prevalence and clinical characteristics.<\/strong> J Affect Disord. 2015;172:24-29 3.7<\/p>\n<\/div><\/div><\/div><\/div><\/div><style type=\"text\/css\">.fusion-accordian  #accordion-880-15 .panel-title a .fa-fusion-box{ color: #ffffff;}.fusion-accordian  #accordion-880-15 .panel-title a .fa-fusion-box:before{ font-size: 16px; width: 16px;}.fusion-accordian  #accordion-880-15 .panel-title a{font-size:24px;}.fusion-accordian  #accordion-880-15 .fa-fusion-box { background-color: #212934;border-color: #212934;}.fusion-accordian  #accordion-880-15 .panel-title a:hover, #accordion-880-15 .fusion-toggle-boxed-mode:hover .panel-title a { color: #65bc7b;}.fusion-accordian  #accordion-880-15 .panel-title .active .fa-fusion-box,.fusion-accordian  #accordion-880-15 .panel-title a:hover .fa-fusion-box { background-color: #65bc7b!important;border-color: #65bc7b!important;}<\/style><div class=\"accordian fusion-accordian\"><div class=\"panel-group\" id=\"accordion-880-15\"><div class=\"fusion-panel panel-default\"><div class=\"panel-heading\"><h4 class=\"panel-title toggle\"><a aria-expanded=\"false\" aria-controls=\"86bc75e8372c05a30\" role=\"button\" data-toggle=\"collapse\" data-parent=\"#accordion-880-15\" data-target=\"#86bc75e8372c05a30\" href=\"#86bc75e8372c05a30\"><span class=\"fusion-toggle-icon-wrapper\" aria-hidden=\"true\"><i class=\"fa-fusion-box\" aria-hidden=\"true\"><\/i><\/span><span class=\"fusion-toggle-heading\">2016<\/span><\/a><\/h4><\/div><div id=\"86bc75e8372c05a30\" class=\"panel-collapse collapse \"><div class=\"panel-body toggle-content fusion-clearfix\">Adams HH, Hibar DP, Chouraki V, Stein JL, Nyquist PA, Renter\u00eda ME, Trompet S, Arias-Vasquez A, Seshadri S, Desrivi\u00e8res S, Beecham AH, Jahanshad N, Wittfeld K, Van der Lee SJ, Abramovic L, Alhusaini S, Amin N, Andersson M, Arfanakis K, Aribisala BS, Armstrong NJ, Athanasiu L, Axelsson T, Beiser A, Bernard M, Bis JC, Blanken LM, Blanton SH, Bohlken MM, Boks MP, Bralten J, Brickman AM, Carmichael O, Chakravarty MM, Chauhan G, Chen Q, Ching CR, Cuellar-Partida G, Braber AD, Doan NT, Ehrlich S, Filippi I, Ge T, Giddaluru S, Goldman AL, Gottesman RF, Greven CU, Grimm O, Griswold ME, Guadalupe T, Hass J, Haukvik UK, Hilal S, Hofer E, Hoehn D, Holmes AJ, Hoogman M, Janowitz D, Jia T, Kasperaviciute D, Kim S, Klein M, Kraemer B, Lee PH, Liao J, Liewald DC, Lopez LM, Luciano M, Macare C, Marquand A, Matarin M, Mather KA, Mattheisen M, Mazoyer B, McKay DR, McWhirter R, Milaneschi Y, Mirza-Schreiber N, Muetzel RL, Maniega SM, Nho K, Nugent AC, Loohuis LM, Oosterlaan J, Papmeyer M, Pappa I, Pirpamer L, Pudas S, P\u00fctz B, Rajan KB, Ramasamy A, Richards JS, Risacher SL, Roiz-Santia\u00f1ez R, Rommelse N, Rose EJ, Royle NA, Rundek T, S\u00e4mann PG, Satizabal CL, Schmaal L, Schork AJ, Shen L, Shin J, Shumskaya E, Smith AV, Sprooten E, Strike LT, Teumer A, Thomson R, Tordesillas-Gutierrez D, Toro R, Trabzuni D, Vaidya D, Van der Grond J, Van der Meer D, Van Donkelaar MM, Van Eijk KR, Van Erp TG, Van Rooij D, Walton E, Westlye LT, Whelan CD, Windham BG, Winkler AM, Woldehawariat G, Wolf C, Wolfers T, Xu B, Yanek LR, Yang J, Zijdenbos A, Zwiers MP, Agartz I, Aggarwal NT, Almasy L, Ames D, Amouyel P, Andreassen OA, Arepalli S, Assareh AA, Barral S, Bastin ME, Becker DM, Becker JT, Bennett DA, Blangero J, van Bokhoven H, Boomsma DI, Brodaty H, Brouwer RM, Brunner HG, Buckner RL, Buitelaar JK, Bulayeva KB, Cahn W, Calhoun VD, Cannon DM, Cavalleri GL, Chen C, Cheng CY, Cichon S, Cookson MR, Corvin A, Crespo-Facorro B, Curran JE, Czisch M, Dale AM, Davies GE, De Geus EJ, De Jager PL, de Zubicaray GI, Delanty N, Depondt C, DeStefano AL, Dillman A, Djurovic S, Donohoe G, Drevets WC, Duggirala R, Dyer TD, Erk S, Espeseth T, Evans DA, Fedko IO, Fern\u00e1ndez G, Ferrucci L, Fisher SE, Fleischman DA, Ford I, Foroud TM, Fox PT, Francks C, Fukunaga M, Gibbs JR, Glahn DC, Gollub RL, G\u00f6ring HH, Grabe HJ, Green RC, Gruber O, Gudnason V, Guelfi S, Hansell NK, Hardy J, Hartman CA, Hashimoto R, Hegenscheid K, Heinz A, Le Hellard S, Hernandez DG, Heslenfeld DJ, Ho BC, Hoekstra PJ, Hoffmann W, Hofman A, Holsboer F, Homuth G, Hosten N, Hottenga JJ, Pol HE, Ikeda M, Ikram MK, Jack CR Jr, Jenkinson M, Johnson R, J\u00f6nsson EG, Jukema JW, Kahn RS, Kanai R, Kloszewska I, Knopman DS, Kochunov P, Kwok JB, Lawrie SM, Lema\u00eetre H, Liu X, Longo DL, Longstreth WT Jr, Lopez OL, Lovestone S, Martinez O, Martinot JL, Mattay VS, McDonald C, McIntosh AM, McMahon KL, McMahon FJ, Mecocci P, Melle I, Meyer-Lindenberg A, Mohnke S, Montgomery GW, Morris DW, Mosley TH, M\u00fchleisen TW, M\u00fcller-Myhsok B, Nalls MA, Nauck M, Nichols TE, Niessen WJ, N\u00f6then MM, Nyberg L, Ohi K, Olvera RL, Ophoff RA, Pandolfo M, Paus T, Pausova Z, Penninx BW, Pike GB, Potkin SG, Psaty BM, Reppermund S, Rietschel M, Roffman JL, Romanczuk-Seiferth N, Rotter JI, Ryten M, Sacco RL, Sachdev PS, Saykin AJ, Schmidt R, Schofield PR, Sigurdsson S, Simmons A, Singleton A, Sisodiya SM, Smith C, Smoller JW, Soininen H, Srikanth V, Steen VM, Stott DJ, Sussmann JE, Thalamuthu A, Tiemeier H, Toga AW, Traynor BJ, Troncoso J, Turner JA, Tzourio C, Uitterlinden AG, Hern\u00e1ndez MC, Van der Brug M, Van der Lugt A, Van der Wee NJ, Van Duijn CM, Van Haren NE, Van T Ent D, Van Tol MJ, Vardarajan BN, Veltman DJ, Vernooij MW, V\u00f6lzke H, Walter H, Wardlaw JM, Wassink TH, Weale ME, Weinberger DR, Weiner MW, Wen W, Westman E, White T, Wong TY, Wright CB, Zielke HR, Zonderman AB, Deary IJ, DeCarli C, Schmidt H, Martin NG, De Craen AJ, 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Nat Neurosci. 2016;19(12):1569-1582<\/p>\n<p>Alassane S, Binquet C, Cottet V, Fleck O, Acar N, Daniel S, Delcourt C, Bretillon L, Bron AM, Creuzot-Garcher C.<strong> Relationships of Macular Pigment Optical Density With Plasma Lutein, Zeaxanthin, and Diet in an Elderly Population: The Montrachet Study<\/strong>. Invest Ophthalmol Vis Sci. 2016;57(3):1160-7<\/p>\n<p>Alassane S, Binquet C, Arnould L, Fleck O, Acar N, Delcourt C, Bretillon L, Bron AM, Creuzot-Garcher C. <strong>Spatial Distribution of Macular Pigment in an Elderly French Population: The Montrachet Study<\/strong>. Invest Ophthalmol Vis Sci. 2016 Aug 1;57(10):4469-4475<\/p>\n<p>All\u00e8s B, Samieri C, Lorrain S, Jutand MA, Carmichael PH, Shatenstein B, Gaudreau P, Payette H, Laurin D, Barberger-Gateau P. <strong>Nutrient Patterns and Their Food Sources in Older Persons from France and Quebec: Dietary and Lifestyle Characteristics<\/strong>. Nutrients. 2016 Apr 19;8(4). pii: E225. doi: 10.3390\/nu8040225<\/p>\n<p>Artaud F, Singh-Manoux A, Dugravot A, Tavernier B, Tzourio C, Elbaz A. <strong>Body mass index trajectories and functional decline in older adults: Three-City Dijon cohort stud<\/strong>y. Eur J Epidemiol. 2016;31(1):73-83. Epub 2015 Apr 9.<\/p>\n<p>Berr C, Gabelle A, Fievet N, Goldberg M, Zins M, Carriere I. <strong>How to optimize the use of biobanks from population-based cohorts in aging research<\/strong>. Biogerontology. 2016;17(1):221-7. Epub 2015 Jun 26<\/p>\n<p>Bergua V, Meillon C, Potvin O, Ritchie K, Tzourio C, Bouisson J, Dartigues JF, Amieva H. <strong>Short STAI-Y anxiety scales: validation and normative data for elderly subjects<\/strong>. Aging Ment Health. 2016;20(9):987-95. Epub 2015 Jun 8<\/p>\n<p>Berticat C, Thomas F, Dauvilliers Y, Jaussent I, Ritchie K, Helmer C, Tzourio C, Raymond M, Artero S. <strong>Excessive daytime sleepiness and antipathogen drug consumption in the elderly: a test of the immune theory of sleep<\/strong>. Sci Rep. 2016 Mar 21;6:23574. doi: 10.1038\/srep23574<\/p>\n<p>Br\u00fcck K, Stel VS, Gambaro G, Hallan S, V\u00f6lzke H, \u00c4rnl\u00f6v J, Kastarinen M, Guessous I, Vinhas J, Stengel B, Brenner H, Chudek J, Romundstad S, Tomson C, Gonzalez AO, Bello AK, Ferrieres J, Palmieri L, Browne G, Capuano V, Van Biesen W, Zoccali C, Gansevoort R, Navis G, Rothenbacher D, Ferraro PM, Nitsch D, Wanner C, Jager KJ; European CKD Burden Consortium. <strong>CKD Prevalence Varies across the European General Population<\/strong>. J Am Soc Nephrol. 2016;27(7):2135-47. Epub 2015 Dec 23<\/p>\n<p>Carri\u00e8re I, Farr\u00e9 A, Norton J, Wyart M, Tzourio C, Noize P, P\u00e9r\u00e8s K, Fourrier-R\u00e9glat A, Ancelin ML. <strong>Patterns of selective serotonin reuptake inhibitor use and risk of falls and fractures in community-dwelling elderly people: the Three-City cohort<\/strong>. Osteoporos Int. 2016;27(11):3187-3195. Epub 2016 Jun 16.<\/p>\n<p>Chan H, Cougnard-Gr\u00e9goire A, Delyfer MN, Combillet F, Rougier MB, Schweitzer C, Dartigues JF, Korobelnik JF, Delcourt C. <strong>Multimodal Imaging of Reticular Pseudodrusen in a Population-Based Setting: The Alienor Study<\/strong>. Invest Ophthalmol Vis Sci. 2016;57(7):3058-65<\/p>\n<p>Charroud C, Le Bars E, Deverdun J, Steffener J, Molino F, Abdennour M, Portet F, Bonafe A, Stern Y, Ritchie K, Akbaraly TN, de Champfleur NM. <strong>Working Memory Performance is related to Intrinsic Resting State Functional Connectivity changes in Community-dwelling Elderly Cohort<\/strong>. Neurobiol Learn Mem. 2016;132:57-66<\/p>\n<p>Chouraki V, Reitz C, Maury F, Bis JC, Bellenguez C, Yu L, Jakobsdottir J, Mukherjee S, Adams HH, Choi SH, Larson EB, Fitzpatrick A, Uitterlinden AG, de Jager PL, Hofman A, Gudnason V, Vardarajan B, Ibrahim-Verbaas C, van der Lee SJ, Lopez O, Dartigues JF, Berr C, Amouyel P, Bennett DA, van Duijn C, DeStefano AL, Launer LJ, Ikram MA, Crane PK, Lambert JC, Mayeux R, Seshadri S; International Genomics of Alzheimer\u2019s Project. <strong>Evaluation of a Genetic Risk Score to Improve Risk Prediction for Alzheimer&rsquo;s Disease<\/strong>. J Alzheimers Dis. 2016;53(3):921-32<\/p>\n<p>Cougnard-Gr\u00e9goire A, Merle BM, Korobelnik JF, Rougier MB, Delyfer MN, Le Goff M, Samieri C, Dartigues JF, Delcourt C. <strong>Olive Oil Consumption and Age-Related Macular Degeneration: The Alienor Study<\/strong>. PLoS One. 2016;11(7):e0160240. doi: 10.1371\/journal.pone.0160240. eCollection 2016<\/p>\n<p>Creuzot-Garcher C, Binquet C, Daniel S, Bretillon L, Acar N, de Lazzer A, Arnould L, Tzourio C, Bron AM, Delcourt C. <strong>The Montrachet Study: study design, methodology and analysis of visual acuity and refractive errors in an elderly population<\/strong>. Acta Ophthalmol. 2016;94(2):e90-7. Epub 2015 Oct 15.<\/p>\n<p>Dandine-Roulland C, Bellenguez C, Debette S, Amouyel P, G\u00e9nin E, Perdry H. <strong>Accuracy of heritability estimations in presence of hidden population stratification<\/strong>. Sci Rep. 2016 May 25;6:26471. doi: 10.1038\/srep26471<\/p>\n<p>Delay C, Grenier-Boley B, Amouyel P, Dumont J, Lambert JC.<strong> miRNA-dependent target regulation: functional characterization of single-nucleotide polymorphisms identified in genome-wide association studies of Alzheimer&rsquo;s disease<\/strong>. Alzheimers Res Ther. 2016 May 24;8(1):20. doi: 10.1186\/s13195-016-0186-x.<\/p>\n<p>Delcourt C, Korobelnik JF, Buitendijk GH, Foster PJ, Hammond CJ, Piermarocchi S, Peto T, Jansonius N, Mirshahi A, Hogg RE, Bretillon L, Topouzis F, Deak G, Grauslund J, Broe R, Souied EH, Creuzot-Garcher C, Sahel J, Daien V, Lehtim\u00e4ki T, Hense HW, Prokofyeva E, Oexle K, Rahi JS, Cumberland PM, Schmitz-Valckenberg S, Fauser S, Bertelsen G, Hoyng C, Bergen A, Silva R, Wolf S, Lotery A, Chakravarthy U, Fletcher A, Klaver CC. <strong>Ophthalmic epidemiology in Europe: the \u00ab\u00a0European Eye Epidemiology\u00a0\u00bb (E3) consortium<\/strong>. Eur J Epidemiol. 2016;31(2):197-210. Epub 2015 Dec 19<\/p>\n<p>Del Gobbo LC, Imamura F, Aslibekyan S, Marklund M, Virtanen JK, Wennberg M, Yakoob MY, Chiuve SE, Dela Cruz L, Frazier-Wood AC, Fretts AM, Guallar E, Matsumoto C, Prem K, Tanaka T, Wu JH, Zhou X, Helmer C, Ingelsson E, Yuan JM, Barberger-Gateau P, Campos H, Chaves PH, Djouss\u00e9 L, Giles GG, G\u00f3mez-Aracena J, Hodge AM, Hu FB, Jansson JH, Johansson I, Khaw KT, Koh WP, Lemaitre RN, Lind L, Luben RN, Rimm EB, Ris\u00e9rus U, Samieri C, Franks PW, Siscovick DS, Stampfer M, Steffen LM, Steffen BT, Tsai MY, van Dam RM, Voutilainen S, Willett WC, Woodward M, Mozaffarian D; Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Fatty Acids and Outcomes Research Consortium (FORCe).<strong> \u03c9-3 Polyunsaturated Fatty Acid Biomarkers and Coronary Heart Disease: Pooling Project of 19 Cohort Studies<\/strong>. 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Epub 2016 Jul 8.<\/p>\n<p>van der Laan SW, Fall T, Soumar\u00e9 A, Teumer A, Sedaghat S, Baumert J, Zabaneh D, van Setten J, Isgum I, Galesloot TE, Arpeg\u00e5rd J, Amouyel P, Trompet S, Waldenberger M, D\u00f6rr M, Magnusson PK, Giedraitis V, Larsson A, Morris AP, Felix JF, Morrison AC, Franceschini N, Bis JC, Kavousi M, O&rsquo;Donnell C, Drenos F, Tragante V, Munroe PB, Malik R, Dichgans M, Worrall BB, Erdmann J, Nelson CP, Samani NJ, Schunkert H, Marchini J, Patel RS, Hingorani AD, Lind L, Pedersen NL, de Graaf J, Kiemeney LA, Baumeister SE, Franco OH, Hofman A, Uitterlinden AG, Koenig W, Meisinger C, Peters A, Thorand B, Jukema JW, Eriksen BO, Toft I, Wilsgaard T, Onland-Moret NC, van der Schouw YT, Debette S, Kumari M, Svensson P, van der Harst P, Kivimaki M, Keating BJ, Sattar N, Dehghan A, Reiner AP, Ingelsson E, den Ruijter HM, de Bakker PI, Pasterkamp G, \u00c4rnl\u00f6v J, Holmes MV, Asselbergs FW. <strong>Cystatin C and Cardiovascular Disease: A Mendelian Randomization Study<\/strong>. J Am Coll Cardiol. 2016;68(9):934-45<\/p>\n<p>van Rheenen W, Shatunov A, Dekker AM, McLaughlin RL, Diekstra FP, Pulit SL, van der Spek RA, V\u00f5sa U, de Jong S, Robinson MR, Yang J, Fogh I, van Doormaal PT, Tazelaar GH, Koppers M, Blokhuis AM, Sproviero W, Jones AR, Kenna KP, van Eijk KR, Harschnitz O, Schellevis RD, Brands WJ, Medic J, Menelaou A, Vajda A, Ticozzi N, Lin K, Rogelj B, Vrabec K, Ravnik-Glava\u010d M, Koritnik B, Zidar J, Leonardis L, Gro\u0161elj LD, Millecamps S, Salachas F, Meininger V, de Carvalho M, Pinto S, Mora JS, Rojas-Garc\u00eda R, Polak M, Chandran S, Colville S, Swingler R, Morrison KE, Shaw PJ, Hardy J, Orrell RW, Pittman A, Sidle K, Fratta P, Malaspina A, Topp S, Petri S, Abdulla S, Drepper C, Sendtner M, Meyer T, Ophoff RA, Staats KA, Wiedau-Pazos M, Lomen-Hoerth C, Van Deerlin VM, Trojanowski JQ, Elman L, McCluskey L, Basak AN, Tunca C, Hamzeiy H, Parman Y, Meitinger T, Lichtner P, Radivojkov-Blagojevic M, Andres CR, Maurel C, Bensimon G, Landwehrmeyer B, Brice A, Payan CA, Saker-Delye S, D\u00fcrr A, Wood NW, Tittmann L, Lieb W, Franke A, Rietschel M, Cichon S, N\u00f6then MM, Amouyel P, Tzourio C, Dartigues JF, Uitterlinden AG, Rivadeneira F, Estrada K, Hofman A, Curtis C, Blauw HM, van der Kooi AJ, de Visser M, Goris A, Weber M, Shaw CE, Smith BN, Pansarasa O, Cereda C, Del Bo R, Comi GP, D&rsquo;Alfonso S, Bertolin C, Sorar\u00f9 G, Mazzini L, Pensato V, Gellera C, Tiloca C, Ratti A, Calvo A, Moglia C, Brunetti M, Arcuti S, Capozzo R, Zecca C, Lunetta C, Penco S, Riva N, Padovani A, Filosto M, Muller B, Stuit RJ; PARALS Registry.; SLALOM Group.; SLAP Registry.; FALS Sequencing Consortium.; SLAGEN Consortium.; NNIPPS Study Group., Blair I, Zhang K, McCann EP, Fifita JA, Nicholson GA, Rowe DB, Pamphlett R, Kiernan MC, Grosskreutz J, Witte OW, Ringer T, Prell T, Stubendorff B, Kurth I, H\u00fcbner CA, Leigh PN, Casale F, Chio A, Beghi E, Pupillo E, Tortelli R, Logroscino G, Powell J, Ludolph AC, Weishaupt JH, Robberecht W, Van Damme P, Franke L, Pers TH, Brown RH, Glass JD, Landers JE, Hardiman O, Andersen PM, Corcia P, Vourc&rsquo;h P, Silani V, Wray NR, Visscher PM, de Bakker PI, van Es MA, Pasterkamp RJ, Lewis CM, Breen G, Al-Chalabi A, van den Berg LH, Veldink JH. <strong>Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis.<\/strong> Nat Genet. 2016;48(9):1043-8. Epub 2016 Jul 25.<\/p>\n<p>Vivot A, Power MC, Glymour MM, Mayeda ER, Benitez A, Spiro A 3rd, Manly JJ, Proust-Lima C, Dufouil C, Gross AL. <strong>Jump, Hop, or Skip: Modeling Practice Effects in Studies of Determinants of Cognitive Change in Older Adults<\/strong>. Am J Epidemiol. 2016;183(4):302-14. Epub 2016 Jan 28<\/p>\n<p>Wyart M, Jaussent I, Ritchie K, Abbar M, Jollant F, Courtet P. <strong>Iowa Gambling Task Performance in Elderly Persons with a Lifetime History of Suicidal Acts<\/strong>. Am J Geriatr Psychiatry. 2016;24(5):399-406. Epub 2015 Dec 24<\/div><\/div><\/div><\/div><\/div><style type=\"text\/css\">.fusion-accordian  #accordion-880-16 .panel-title a .fa-fusion-box{ color: #ffffff;}.fusion-accordian  #accordion-880-16 .panel-title a .fa-fusion-box:before{ font-size: 16px; width: 16px;}.fusion-accordian  #accordion-880-16 .panel-title a{font-size:24px;}.fusion-accordian  #accordion-880-16 .fa-fusion-box { background-color: #212934;border-color: #212934;}.fusion-accordian  #accordion-880-16 .panel-title a:hover, #accordion-880-16 .fusion-toggle-boxed-mode:hover .panel-title a { color: #65bc7b;}.fusion-accordian  #accordion-880-16 .panel-title .active .fa-fusion-box,.fusion-accordian  #accordion-880-16 .panel-title a:hover .fa-fusion-box { background-color: #65bc7b!important;border-color: #65bc7b!important;}<\/style><div class=\"accordian fusion-accordian\"><div class=\"panel-group\" id=\"accordion-880-16\"><div class=\"fusion-panel panel-default\"><div class=\"panel-heading\"><h4 class=\"panel-title toggle\"><a aria-expanded=\"false\" aria-controls=\"e9c22de4969ac8b04\" role=\"button\" data-toggle=\"collapse\" data-parent=\"#accordion-880-16\" data-target=\"#e9c22de4969ac8b04\" href=\"#e9c22de4969ac8b04\"><span class=\"fusion-toggle-icon-wrapper\" aria-hidden=\"true\"><i class=\"fa-fusion-box\" aria-hidden=\"true\"><\/i><\/span><span class=\"fusion-toggle-heading\">2017<\/span><\/a><\/h4><\/div><div id=\"e9c22de4969ac8b04\" class=\"panel-collapse collapse \"><div class=\"panel-body toggle-content fusion-clearfix\">\n<p>Amadieu C, Lef\u00e8vre-Arbogast S, Delcourt C, Dartigues JF, Helmer C, F\u00e9art C, Samieri C. <strong>Nutrient biomarker patterns and long-term risk of dementia in older adults<\/strong>. Alzheimers Dement. 2017;13(10):1125-1132. Epub 2017 Mar 18<\/p>\n<p>Ancelin ML, Scali J, Norton J, Ritchie K, Dupuy AM, Chaudieu I, Ryan J. <strong>The effect of an adverse psychological environment on salivary cortisol levels in the elderly differs by 5-HTTLPR genotype<\/strong>. Neurobiol Stress. 2017;7:38-46<\/p>\n<p>Ancelin ML, Scali J, Norton J, Ritchie K, Dupuy AM, Chaudieu I, Ryan J. <strong>Heterogeneity in HPA axis dysregulation and serotonergic vulnerability to depression<\/strong>. Psychoneuroendocrinology. 2017;77:90-94. Epub 2016 Dec 5<\/p>\n<p>Bellenguez C, Charbonnier C, Grenier-Boley B, Quenez O, Le Guennec K, Nicolas G, Chauhan G, Wallon D, Rousseau S, Richard AC, Boland A, Bourque G, Munter HM, Olaso R, Meyer V, Rollin-Sillaire A, Pasquier F, Letenneur L, Redon R, Dartigues JF, Tzourio C, Frebourg T, Lathrop M, Deleuze JF, Hannequin D, Genin E, Amouyel P, Debette S, Lambert JC, Campion D; CNR MAJ collaborators. <strong>Contribution to Alzheimer&rsquo;s disease risk of rare variants in TREM2, SORL1, and ABCA7 in 1779 cases and 1273 controls<\/strong>. Neurobiol Aging. 2017;59:220.e1-220.e9. Epub 2017 Jul 14<\/p>\n<p>Calati R, Courtet P, Norton J, Ritchie K, Artero S. <strong>Association between lifetime headache and history of suicide attempts in the elderly<\/strong>. Eur Psychiatry. 2017;41:132-139. Epub 2017 Jan 31<\/p>\n<p>Carri\u00e8re I, Norton J, Farr\u00e9 A, Wyart M, Tzourio C, Noize P, P\u00e9r\u00e8s K, Fourrier-R\u00e9glat A, Ritchie K, Ancelin ML. <strong>Antidepressant use and cognitive decline in community-dwelling elderly people &#8211; The Three-City Cohort<\/strong>. BMC Med. 2017;15(1):81<\/p>\n<p>Carri\u00e8re I, Farr\u00e9 A, Proust-Lima C, Ryan J, Ancelin ML, Ritchie K. <strong>Chronic and remitting trajectories of depressive symptoms in the elderly. Characterisation and risk factors<\/strong>. Epidemiol Psychiatr Sci. 2017;26(2):146-156. Epub 2016 Jan 15<\/p>\n<p>Chibnik LB, Wolters FJ, B\u00e4ckman K, Beiser A, Berr C, Bis JC, Boerwinkle E, Bos D, Brayne C, Dartigues JF, Darweesh SKL, Debette S, Davis-Plourde KL, Dufouil C, Fornage M, Grasset L, Gudnason V, Hadjichrysanthou C, Helmer C, Ikram MA, Ikram MK, Kern S, Kuller LH, Launer L, Lopez OL, Matthews F, Meirelles O, Mosley T, Ower A, Psaty BM, Satizabal CL, Seshadri S, Skoog I, Stephan BCM, Tzourio C, Waziry R, Wong MM, Zettergren A, Hofman A. <strong>Trends in the incidence of dementia: design and methods in the Alzheimer Cohorts Consortium<\/strong>. Eur J Epidemiol. 2017;32(10):931-938. Epub 2017 Oct 23<\/p>\n<p>Colijn JM, Buitendijk GHS, Prokofyeva E, Alves D, Cachulo ML, Khawaja AP, Cougnard-Gregoire A, Merle BMJ, Korb C, Erke MG, Bron A, Anastasopoulos E, Meester-Smoor MA, Segato T, Piermarocchi S, de Jong PTVM, Vingerling JR; EYE-RISK consortium, Topouzis F, Creuzot-Garcher C, Bertelsen G, Pfeiffer N, Fletcher AE, Foster PJ, Silva R, Korobelnik JF, Delcourt C, Klaver CCW; European Eye Epidemiology (E3) consortium. <strong>Prevalence of Age-Related Macular Degeneration in Europe: The Past and the Future<\/strong>. Ophthalmology. 2017 Dec;124(12):1753-1763. Epub 2017 Jul 14<\/p>\n<p>Cremer A, Soumar\u00e9 A, Berr C, Dartigues JF, Gabelle A, Gosse P, Tzourio C. <strong>Orthostatic Hypotension and Risk of Incident Dementia: Results From a 12-Year Follow-Up of the Three-City Study Cohor<\/strong>t. Hypertension. 2017;70(1):44-49. Epub 2017 May 30.<\/p>\n<p>Dufouil C, Beiser AS, McClure LA, Wolf PA, Tzourio C, Howard VJ, Westwood AJ, Himali JJ, Sullivan LM, Aparicio HJ, Kelly-Hayes M, Ritchie K, Kase CS, Pikula A, Romero JR, D&rsquo;Agostino RB Sr, Samieri C, Vasan RS, Ch\u00eane G, Howard G, Seshadri S. <strong>A Revised Framingham Stroke Risk Profile to Reflect Temporal Trends<\/strong>. Circulation. 2017;135(12):1145-1159. Epub 2017 Feb 3.<\/p>\n<p>Dumurgier J, Artaud F, Touraine C, Rouaud O, Tavernier B, Dufouil C, Singh-Manoux A, Tzourio C, Elbaz A. <strong>Gait Speed and Decline in Gait Speed as Predictors of Incident Dementia<\/strong>. J Gerontol A Biol Sci Med Sci. 2017;72(5):655-661<\/p>\n<p>Duperron MG, Tzourio C, Sargurupremraj M, Mazoyer B, Soumar\u00e9 A, Schilling S, Amouyel P, Chauhan G, Zhu YC, Debette S. <strong>Burden of Dilated Perivascular Spaces, an Emerging Marker of Cerebral Small Vessel Disease, Is Highly Heritable<\/strong>. Stroke. 2018;49(2):282-287Epub 2018 Jan 8<\/p>\n<p>Elbejjani M, Fuhrer R, Abrahamowicz M, Mazoyer B, Crivello F, Tzourio C, Dufouil C. <strong>Life-Course Socioeconomic Position and Hippocampal Atrophy in a Prospective Cohort of Older Adults<\/strong>. Psychosom Med. 2017;79(1):14-23.<\/p>\n<p>Feart C, Helmer C, Merle B, Herrmann FR, Annweiler C, Dartigues JF, Delcourt C, Samieri C. <strong>Associations of lower vitamin D concentrations with cognitive decline and long-term risk of dementia and Alzheimer&rsquo;s disease in older adults<\/strong>. Alzheimers Dement. 2017;13(11):1207-1216. Epub 2017 May 16<\/p>\n<p>Frison E, Boirie Y, Peuchant E, Tabue-Teguo M, Barberger-Gateau P, F\u00e9art C. <strong>Plasma fatty acid biomarkers are associated with gait speed in community-dwelling older adults: The Three-City-Bordeaux study<\/strong>. Clin Nutr. 2017;36(2):416-422. Epub 2015 Dec 18<\/p>\n<p>Gattoussi S, Cougnard-Gr\u00e9goire A, Delyfer MN, Rougier MB, Schweitzer C, Delcourt C, Korobelnik JF. <strong>Vitreomacular Adhesion and Its Association With Age-Related Macular Degeneration in a Population-Based Setting: The Alienor Study<\/strong>. Invest Ophthalmol Vis Sci. 2017;58(4):2180-2186<\/p>\n<p>Gaye B, Canonico M, Perier MC, Samieri C, Berr C, Dartigues JF, Tzourio C, Elbaz A, Empana JP. <strong>Ideal Cardiovascular Health, Mortality, and Vascular Events in Elderly Subjects: The Three-City Study<\/strong>. J Am Coll Cardiol. 2017;69(25):3015-3026<\/p>\n<p>Geissler JM; International Parkinson Disease Genomics Consortium members, Romanos M, Gerlach M, Berg D, Schulte C. <strong>No genetic association between attention-deficit\/hyperactivity disorder (ADHD) and Parkinson&rsquo;s disease in nine ADHD candidate SNPs<\/strong>. Atten Defic Hyperact Disord. 2017;9(2):121-127. Epub 2017 Feb 7<\/p>\n<p>Gonzalez-Cola\u00e7o Harmand M, Meillon C, Bergua V, Tabue Teguo M, Dartigues JF, Avila-Funes JA, Amieva H. <strong>Comparing the predictive value of three definitions of frailty: Results from the Three-City study<\/strong>. Arch Gerontol Geriatr. 2017;72:153-163. Epub 2017 Jun 17<\/p>\n<p>Gorski M, van der Most PJ, Teumer A, Chu AY, Li M, Mijatovic V, Nolte IM, Cocca M, Taliun D, Gomez F, Li Y, Tayo B, Tin A, Feitosa MF, Aspelund T, Attia J, Biffar R, Bochud M, Boerwinkle E, Borecki I, Bottinger EP, Chen MH, Chouraki V, Ciullo M, Coresh J, Cornelis MC, Curhan GC, d&rsquo;Adamo AP, Dehghan A, Dengler L, Ding J, Eiriksdottir G, Endlich K, Enroth S, Esko T, Franco OH, Gasparini P, Gieger C, Girotto G, Gottesman O, Gudnason V, Gyllensten U, Hancock SJ, Harris TB, Helmer C, H\u00f6llerer S, Hofer E, Hofman A, Holliday EG, Homuth G, Hu FB, Huth C, Hutri-K\u00e4h\u00f6nen N, Hwang SJ, Imboden M, Johansson \u00c5, K\u00e4h\u00f6nen M, K\u00f6nig W, Kramer H, Kr\u00e4mer BK, Kumar A, Kutalik Z, Lambert JC, Launer LJ, Lehtim\u00e4ki T, de Borst MH, Navis G, Swertz M, Liu Y, Lohman K, Loos RJF, Lu Y, Lyytik\u00e4inen LP, McEvoy MA, Meisinger C, Meitinger T, Metspalu A, Metzger M, Mihailov E, Mitchell P, Nauck M, Oldehinkel AJ, Olden M, Wjh Penninx B, Pistis G, Pramstaller PP, Probst-Hensch N, Raitakari OT, Rettig R, Ridker PM, Rivadeneira F, Robino A, Rosas SE, Ruderfer D, Ruggiero D, Saba Y, Sala C, Schmidt H, Schmidt R, Scott RJ, Sedaghat S, Smith AV, Sorice R, Stengel B, Stracke S, Strauch K, Toniolo D, Uitterlinden AG, Ulivi S, Viikari JS, V\u00f6lker U, Vollenweider P, V\u00f6lzke H, Vuckovic D, Waldenberger M, Jin Wang J, Yang Q, Chasman DI, Tromp G, Snieder H, Heid IM, Fox CS, K\u00f6ttgen A, Pattaro C, B\u00f6ger CA, Fuchsberger C. <strong>1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function<\/strong>. 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Nat Commun. 2017;8:13624. doi: 10.1038\/ncomms13624<\/p>\n<p>Kabor\u00e9 J, Metzger M, Helmer C, Berr C, Tzourio C, Drueke TB, Massy ZA, Stengel B.<strong> Hypertension Control, Apparent Treatment Resistance, and Outcomes in the Elderly Population With Chronic Kidney Disease<\/strong>. Kidney Int Rep. 2017 Mar; 2(2): 180\u2013191. Epub 2016 Oct 31<\/p>\n<p>Kuate-Tegueu C, Avila-Funes JA, Simo N, Le Goff M, Ami\u00e9va H, Dartigues JF, Tabue-Teguo M. <strong>Association of Gait Speed, Psychomotor Speed, and Dementia<\/strong>. J Alzheimers Dis. 2017;60(2):585-592.<\/p>\n<p>Lipnicki DM, Crawford JD, Dutta R, Thalamuthu A, Kochan NA, Andrews G, Lima-Costa MF, Castro-Costa E, Brayne C, Matthews FE, Stephan BC, Lipton RB, Katz MJ, Ritchie K, Scali J, Ancelin ML, Scarmeas N, Yannakoulia M, Dardiotis E, Lam LC, Wong CH, Fung AW, Guaita A, Vaccaro R, Davin A, Kim KW, Han JW, Kim TH, Anstey KJ, Cherbuin N, Butterworth P, Scazufca M, Kumagai S, Chen S, Narazaki K, Ng TP, Gao Q, Reppermund S, Brodaty H, Lobo A, Lopez-Anton R, Santab\u00e1rbara J, Sachdev PS; Cohort Studies of Memory in an International Consortium (COSMIC). <strong>Age-related cognitive decline and associations with sex, education and apolipoprotein E genotype across ethnocultural groups and geographic regions: a collaborative cohort study<\/strong>. PLoS Med. 2017;14(3):e1002261<\/p>\n<p>McLaughlin RL, Schijven D, van Rheenen W, van Eijk KR, O&rsquo;Brien M, Kahn RS, Ophoff RA, Goris A, Bradley DG, Al-Chalabi A, van den Berg LH, Luykx JJ, Hardiman O, Veldink JH; Project MinE GWAS Consortium; Schizophrenia Working Group of the Psychiatric Genomics Consortium. <strong>Genetic correlation between amyotrophic lateral sclerosis and schizophrenia<\/strong>. Nat Commun. 2017 Mar 21;8:14774. doi: 10.1038\/ncomms14774<\/p>\n<p>Marie Dit Asse L, Fabrigoule C, Helmer C, Laumon B, Berr C, Rouaud O, Auriacombe S, Lafont S.<strong> Gender effect on driving cessation in pre-dementia and dementia phases: results of the 3C population-based study<\/strong>. Int J Geriatr Psychiatry. 2017 Oct;32(10):1049-1058<\/p>\n<p>M\u00e9ndez-G\u00f3mez JL, Rougier MB, Tellouck L, Korobelnik JF, Schweitzer C, Delyfer MN, Amieva H, Dartigues JF, Delcourt C, Helmer C. <strong>Peripapillary Retinal Nerve Fiber Layer Thickness and the Evolution of Cognitive Performance in an Elderly Population<\/strong>. Front Neurol. 2017;8:93. doi: 10.3389\/fneur.2017.00093. eCollection 2017<\/p>\n<p>Mura T, Baramova M, Gabelle A, Artero S, Dartigues JF, Amieva H, Berr C. <strong>Predicting dementia using socio-demographic characteristics and the Free and Cued Selective Reminding Test in the general population<\/strong>. Alzheimers Res Ther. 2017;9(1):21<\/p>\n<p>Na\u00ebl V, P\u00e9r\u00e8s K, Carri\u00e8re I, Daien V, Scherlen AC, Arleo A, Korobelnik JF, Delcourt C, Helmer C. <strong>Visual Impairment, Undercorrected Refractive Errors, and Activity Limitations in Older Adults: Findings From the Three-City Alienor Study<\/strong>. Invest Ophthalmol Vis Sci. 2017;58(4):2359-2365<\/p>\n<p>NCD Risk Factor Collaboration (NCD-RisC). <strong>Worldwide trends in blood pressure from 1975 to 2015: a pooled analysis of 1479 population-based measurement studies with 19\u00b71 million participants<\/strong>. Lancet. 2017;389(10064):37-55. Epub 2016 Nov 16.<\/p>\n<p>NCD Risk Factor Collaboration (NCD-RisC). <strong>Worldwide trends in body-mass index, underweight, overweight, and obesity from 1975 to 2016: a pooled analysis of 2416 population-based measurement studies in 128\u00b79 million children, adolescents, and adults<\/strong>. Lancet 2017 16;390(10113):2627-2642. Epub 2017 Oct 10<\/p>\n<p>33. Pelletier A, Bernard C, Dilharreguy B, Helmer C, Le Goff M, Chanraud S, Dartigues JF, Allard M, Amieva H, Catheline GW. <strong>Patterns of brain atrophy associated with episodic memory and semantic fluency decline in aging<\/strong>. Aging (Albany NY). 2017;9(3):741-752<\/p>\n<p>P\u00e9r\u00e8s K, Matharan F, Daien V, Nael V, Edjolo A, Bourdel-Marchasson I 1st, Ritchie K, Tzourio C, Delcourt C, Carri\u00e8re I. <strong>Visual Loss and Subsequent Activity Limitations in the Elderly: The French Three-City Cohor<\/strong>t. Am J Public Health. 2017;107(4):564-569<\/p>\n<p>Pilleron S, Ajana S, Jutand MA, Helmer C, Dartigues JF, Samieri C, F\u00e9art C. <strong>Dietary Patterns and 12-Year Risk of Frailty: Results From the Three-City Bordeaux Study<\/strong>. J Am Med Dir Assoc. 2017;18(2):169-175. Epub 2016 Nov 12<\/p>\n<p>Pilleron S, Rajaobelina K, Tabue Teguo M, Dartigues JF, Helmer C, Delcourt C, Rigalleau V, F\u00e9art C. <strong>Accumulation of advanced glycation end products evaluated by skin autofluorescence and incident frailty in older adults from the Bordeaux Three-City cohort<\/strong>. PLoS One. 2017 Oct 17;12(10):e0186087. doi: 10.1371\/journal.pone.0186087. eCollection 2017<\/p>\n<p>Rajaobelina K, Helmer C, V\u00e9layoudom-C\u00e9phise FL, Nov S, Farges B, Pupier E, Blanco L, Hugo M, Gin H, Rigalleau V. <strong>Progression of skin autofluorescence of AGEs over 4 years in patients with type 1 diabetes<\/strong>. Diabetes Metab Res Rev. 2017;33(7). Epub 2017 Sep 5.<\/p>\n<p>Robak LA, Jansen IE, van Rooij J, Uitterlinden AG, Kraaij R, Jankovic J; International Parkinson\u2019s Disease Genomics Consortium (IPDGC), Heutink P, Shulman JM; IPDGC Consortium members; International Parkinson\u2019s Disease Genomics Consortium (IPDGC).<strong> Excessive burden of lysosomal storage disorder gene variants in Parkinson&rsquo;s disease<\/strong>. Brain. 2017;140(12):3191-3203<\/p>\n<p>Rondeau V, Mauguen A, Laurent A, Berr C, Helmer C.<strong> Dynamic prediction models for clustered and interval-censored outcomes: Investigating the intra-couple correlation in the risk of dementia<\/strong>. Stat Methods Med Res. 2017;26(5):2168-2183. Epub 2015 Jul 15<\/p>\n<p>Rouch L, Cestac P, Cool C, Helmer C, Dartigues JF, Berr C, Rouaud O, Vellas B, Andrieu S. <strong>Effectiveness of a standardized and specific follow-up in memory centers in patients with Alzheimer&rsquo;s disease<\/strong>. Curr Alzheimer Res. 2017;14(3):255-267<\/p>\n<p>Ryan J, Pilkington L, Neuhaus K, Ritchie K, Ancelin ML, Saffery R. <strong>Investigating the epigenetic profile of the inflammatory gene IL-6 in late-life depression<\/strong>. BMC Psychiatry. 2017;17(1):354. doi: 10.1186\/s12888-017-1515-8<\/p>\n<p>Schilling S, Tzourio C, Soumar\u00e9 A, Kaffashian S, Dartigues JF, Ancelin ML, Samieri C, Dufouil C, Debette S. <strong>Differential associations of plasma lipids with incident dementia and dementia subtypes in the 3C Study: A longitudinal, population-based prospective cohort study<\/strong>. PLoS Med. 2017;14(3):e1002265<\/p>\n<p>Sims R, van der Lee SJ, Naj AC, Bellenguez C, Badarinarayan N, Jakobsdottir J, Kunkle BW, Boland A, Raybould R, Bis JC, Martin ER, Grenier-Boley B, Heilmann-Heimbach S, Chouraki V, Kuzma AB, Sleegers K, Vronskaya M, Ruiz A, Graham RR, Olaso R, Hoffmann P, Grove ML, Vardarajan BN, Hiltunen M, N\u00f6then MM, White CC, Hamilton-Nelson KL, Epelbaum J, Maier W, Choi SH, Beecham GW, Dulary C, Herms S, Smith AV, Funk CC, Derbois C, Forstner AJ, Ahmad S, Li H, Bacq D, Harold D, Satizabal CL, Valladares O, Squassina A, Thomas R, Brody JA, Qu L, S\u00e1nchez-Juan P, Morgan T, Wolters FJ, Zhao Y, Garcia FS, Denning N, Fornage M, Malamon J, Naranjo MCD, Majounie E, Mosley TH, Dombroski B, Wallon D, Lupton MK, Dupuis J, Whitehead P, Fratiglioni L, Medway C, Jian X, Mukherjee S, Keller L, Brown K, Lin H, Cantwell LB, Panza F, McGuinness B, Moreno-Grau S, Burgess JD, Solfrizzi V, Proitsi P, Adams HH, Allen M, Seripa D, Pastor P, Cupples LA, Price ND, Hannequin D, Frank-Garc\u00eda A, Levy D, Chakrabarty P, Caffarra P, Giegling I, Beiser AS, Giedraitis V, Hampel H, Garcia ME, Wang X, Lannfelt L, Mecocci P, Eiriksdottir G, Crane PK, Pasquier F, Boccardi V, Hen\u00e1ndez I, Barber RC, Scherer M, Tarraga L, Adams PM, Leber M, Chen Y, Albert MS, Riedel-Heller S, Emilsson V, Beekly D, Braae A, Schmidt R, Blacker D, Masullo C, Schmidt H, Doody RS, Spalletta G, Jr WTL, Fairchild TJ, Boss\u00f9 P, Lopez OL, Frosch MP, Sacchinelli E, Ghetti B, Yang Q, Huebinger RM, Jessen F, Li S, Kamboh MI, Morris J, Sotolongo-Grau O, Katz MJ, Corcoran C, Dunstan M, Braddel A, Thomas C, Meggy A, Marshall R, Gerrish A, Chapman J, Aguilar M, Taylor S, Hill M, Fair\u00e9n MD, Hodges A, Vellas B, Soininen H, Kloszewska I, Daniilidou M, Uphill J, Patel Y, Hughes JT, Lord J, Turton J, Hartmann AM, Cecchetti R, Fenoglio C, Serpente M, Arcaro M, Caltagirone C, Orfei MD, Ciaramella A, Pichler S, Mayhaus M, Gu W, Lle\u00f3 A, Fortea J, Blesa R, Barber IS, Brookes K, Cupidi C, Maletta RG, Carrell D, Sorbi S, Moebus S, Urbano M, Pilotto A, Kornhuber J, Bosco P, Todd S, Craig D, Johnston J, Gill M, Lawlor B, Lynch A, Fox NC, Hardy J; ARUK Consortium, Albin RL, Apostolova LG, Arnold SE, Asthana S, Atwood CS, Baldwin CT, Barnes LL, Barral S, Beach TG, Becker JT, Bigio EH, Bird TD, Boeve BF, Bowen JD, Boxer A, Burke JR, Burns JM, Buxbaum JD, Cairns NJ, Cao C, Carlson CS, Carlsson CM, Carney RM, Carrasquillo MM, Carroll SL, Diaz CC, Chui HC, Clark DG, Cribbs DH, Crocco EA, DeCarli C, Dick M, Duara R, Evans DA, Faber KM, Fallon KB, Fardo DW, Farlow MR, Ferris S, Foroud TM, Galasko DR, Gearing M, Geschwind DH, Gilbert JR, Graff-Radford NR, Green RC, Growdon JH, Hamilton RL, Harrell LE, Honig LS, Huentelman MJ, Hulette CM, Hyman BT, Jarvik GP, Abner E, Jin LW, Jun G, Karydas A, Kaye JA, Kim R, Kowall NW, Kramer JH, LaFerla FM, Lah JJ, Leverenz JB, Levey AI, Li G, Lieberman AP, Lunetta KL, Lyketsos CG, Marson DC, Martiniuk F, Mash DC, Masliah E, McCormick WC, McCurry SM, McDavid AN, McKee AC, Mesulam M, Miller BL, Miller CA, Miller JW, Morris JC, Murrell JR, Myers AJ, O&rsquo;Bryant S, Olichney JM, Pankratz VS, Parisi JE, Paulson HL, Perry W, Peskind E, Pierce A, Poon WW, Potter H, Quinn JF, Raj A, Raskind M, Reisberg B, Reitz C, Ringman JM, Roberson ED, Rogaeva E, Rosen HJ, Rosenberg RN, Sager MA, Saykin AJ, Schneider JA, Schneider LS, Seeley WW, Smith AG, Sonnen JA, Spina S, Stern RA, Swerdlow RH, Tanzi RE, Thornton-Wells TA, Trojanowski JQ, Troncoso JC, Van Deerlin VM, Van Eldik LJ, Vinters HV, Vonsattel JP, Weintraub S, Welsh-Bohmer KA, Wilhelmsen KC, Williamson J, Wingo TS, Woltjer RL, Wright CB, Yu CE, Yu L, Garzia F, Golamaully F, Septier G, Engelborghs S, Vandenberghe R, De Deyn PP, Fernadez CM, Benito YA, Thonberg H, Forsell C, Lilius L, Kinhult-St\u00e4hlbom A, Kilander L, Brundin R, Concari L, Helisalmi S, Koivisto AM, Haapasalo A, Dermecourt V, Fievet N, Hanon O, Dufouil C, Brice A, Ritchie K, Dubois B, Himali JJ, Keene CD, Tschanz J, Fitzpatrick AL, Kukull WA, Norton M, Aspelund T, Larson EB, Munger R, Rotter JI, Lipton RB, Bullido MJ, Hofman A, Montine TJ, Coto E, Boerwinkle E, Petersen RC, Alvarez V, Rivadeneira F, Reiman EM, Gallo M, O&rsquo;Donnell CJ, Reisch JS, Bruni AC, Royall DR, Dichgans M, Sano M, Galimberti D, St George-Hyslop P, Scarpini E, Tsuang DW, Mancuso M, Bonuccelli U, Winslow AR, Daniele A, Wu CK; GERAD\/PERADES, CHARGE, ADGC, EADI, Peters O, Nacmias B, Riemenschneider M, Heun R, Brayne C, Rubinsztein DC, Bras J, Guerreiro R, Al-Chalabi A, Shaw CE, Collinge J, Mann D, Tsolaki M, Clarim\u00f3n J, Sussams R, Lovestone S, O&rsquo;Donovan MC, Owen MJ, Behrens TW, Mead S, Goate AM, Uitterlinden AG, Holmes C, Cruchaga C, Ingelsson M, Bennett DA, Powell J, Golde TE, Graff C, De Jager PL, Morgan K, Ertekin-Taner N, Combarros O, Psaty BM, Passmore P, Younkin SG, Berr C, Gudnason V, Rujescu D, Dickson DW, Dartigues JF, DeStefano AL, Ortega-Cubero S, Hakonarson H, Campion D, Boada M, Kauwe JK, Farrer LA, Van Broeckhoven C, Ikram MA, Jones L, Haines JL, Tzourio C, Launer LJ, Escott-Price V, Mayeux R, Deleuze JF, Amin N, Holmans PA, Pericak-Vance MA, Amouyel P, van Duijn CM, Ramirez A, Wang LS, Lambert JC, Seshadri S, Williams J, Schellenberg GD. <strong>Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer&rsquo;s disease<\/strong>. Nat Genet. 2017;49(9):1373-1384. Epub 2017 Jul 17<\/p>\n<p>Tabue-Teguo M, Grasset L, Avila-Funes JA, Genuer R, Proust-Lima C, P\u00e9res K, F\u00e9art C, Amieva H, Harmand MG, Helmer C, Salles N, Rainfray M, Dartigues JF. <strong>Prevalence and Co-Occurrence of Geriatric Syndromes in People Aged 75 Years and Older in France: Results From the Bordeaux Three-city Study<\/strong>. J Gerontol A Biol Sci Med Sci. 2017 May 24. doi: 10.1093\/gerona\/glx068.\u00a0<\/p>\n<p>Tully PJ, Tzourio C. <strong>Psychiatric correlates of blood pressure variability in the elderly: The Three City cohort study<\/strong>. Physiol Behav. 2017;168:91-97.<\/p>\n<p>Tully PJ, Debette S, Mazoyer B, Tzourio C. White Matter Lesions are <strong>Associated with Specific Depressive Symptom Trajectories among Incident Depression and Dementia Populations: Three-City Dijon MRI Study<\/strong>. Am J Geriatr Psychiatry. 2017 Dec;25(12):1311-1321. Epub 2017 Jul 5<\/p>\n<p>Tully PJ, Qchiqach S, Pereira E, Debette S, Mazoyer B, Tzourio C. <strong>Development and validation of a priori risk model for extensive white matter lesions in people age 65 years or older: the Dijon MRI study<\/strong>. BMJ Open. 2017;7(12):e018328.<\/p>\n<p>Tzourio C, Hanon O, Godin O, Soumar\u00e9 A, Dufouil C.<strong> Impact of home blood pressure monitoring on blood pressure control in older individuals: a French randomized study<\/strong>. J Hypertens. 2017;35(3):612-620<\/p>\n<p>Veronese N, Cereda E, Stubbs B, Solmi M, Luchini C, Manzato E, Sergi G, Manu P, Harris T, Fontana L, Strandberg T, Amieva H, Dumurgier J, Elbaz A, Tzourio C, Eicholzer M, Rohrmann S, Moretti C, D&rsquo;Ascenzo F, Quadri G, Polidoro A, Louren\u00e7o RA, Moreira VG, Sanchis J, Scotti V, Maggi S, Correll CU. <strong>Risk of cardiovascular disease morbidity and mortality in frail and pre-frail older adults: results from a meta-analysis and exploratory meta-regression analysis<\/strong>. Ageing Res Rev. 2017;35:63-73. Epub 2017 Jan 28<\/p>\n<p>Wain LV, Vaez A, Jansen R, Joehanes R, van der Most PJ, Erzurumluoglu AM, O&rsquo;Reilly PF, Cabrera CP, Warren HR, Rose LM, Verwoert GC, Hottenga JJ, Strawbridge RJ, Esko T, Arking DE, Hwang SJ, Guo X, Kutalik Z, Trompet S, Shrine N, Teumer A, Ried JS, Bis JC, Smith AV, Amin N, Nolte IM, Lyytik\u00e4inen LP, Mahajan A, Wareham NJ, Hofer E, Joshi PK, Kristiansson K, Traglia M, Havulinna AS, Goel A, Nalls MA, S\u00f5ber S, Vuckovic D, Luan J, Del Greco M F, Ayers KL, Marrugat J, Ruggiero D, Lopez LM, Niiranen T, Enroth S, Jackson AU, Nelson CP, Huffman JE, Zhang W, Marten J, Gandin I, Harris SE, Zemunik T, Lu Y, Evangelou E, Shah N, de Borst MH, Mangino M, Prins BP, Campbell A, Li-Gao R, Chauhan G, Oldmeadow C, Abecasis G, Abedi M, Barbieri CM, Barnes MR, Batini C, Beilby J, Blake T, Boehnke M, Bottinger EP, Braund PS, Brown M, Brumat M, Campbell H, Chambers JC, Cocca M, Collins F, Connell J, Cordell HJ, Damman JJ, Davies G, de Geus EJ, de Mutsert R, Deelen J, Demirkale Y, Doney ASF, D\u00f6rr M, Farrall M, Ferreira T, Fr\u00e5nberg M, Gao H, Giedraitis V, Gieger C, Giulianini F, Gow AJ, Hamsten A, Harris TB, Hofman A, Holliday EG, Hui J, Jarvelin MR, Johansson \u00c5, Johnson AD, Jousilahti P, Jula A, K\u00e4h\u00f6nen M, Kathiresan S, Khaw KT, Kolcic I, Koskinen S, Langenberg C, Larson M, Launer LJ, Lehne B, Liewald DCM, Lin L, Lind L, Mach F, Mamasoula C, Menni C, Mifsud B, Milaneschi Y, Morgan A, Morris AD, Morrison AC, Munson PJ, Nandakumar P, Nguyen QT, Nutile T, Oldehinkel AJ, Oostra BA, Org E, Padmanabhan S, Palotie A, Par\u00e9 G, Pattie A, Penninx BWJH, Poulter N, Pramstaller PP, Raitakari OT, Ren M, Rice K, Ridker PM, Riese H, Ripatti S, Robino A, Rotter JI, Rudan I, Saba Y, Saint Pierre A, Sala CF, Sarin AP, Schmidt R, Scott R, Seelen MA, Shields DC, Siscovick D, Sorice R, Stanton A, Stott DJ, Sundstr\u00f6m J, Swertz M, Taylor KD, Thom S, Tzoulaki I, Tzourio C, Uitterlinden AG, V\u00f6lker U, Vollenweider P, Wild S, Willemsen G, Wright AF, Yao J, Th\u00e9riault S, Conen D, Attia J, Sever P, Debette S, Mook-Kanamori DO, Zeggini E, Spector TD, van der Harst P, Palmer CNA, Vergnaud AC, Loos RJF, Polasek O, Starr JM, Girotto G, Hayward C, Kooner JS, Lindgren CM, Vitart V, Samani NJ, Tuomilehto J, Gyllensten U, Knekt P, Deary IJ, Ciullo M, Elosua R, Keavney BD, Hicks AA, Scott RA, Gasparini P, Laan M, Liu Y, Watkins H, Hartman CA, Salomaa V, Toniolo D, Perola M, Wilson JF, Schmidt H, Zhao JH, Lehtim\u00e4ki T, van Duijn CM, Gudnason V, Psaty BM, Peters A, Rettig R, James A, Jukema JW, Strachan DP, Palmas W, Metspalu A, Ingelsson E, Boomsma DI, Franco OH, Bochud M, Newton-Cheh C, Munroe PB, Elliott P, Chasman DI, Chakravarti A, Knight J, Morris AP, Levy D, Tobin MD, Snieder H, Caulfield MJ, Ehret GB. 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Wu JHY, Marklund M, Imamura F, Tintle N, Ardisson Korat AV, de Goede J, Zhou X, Yang WS, de Oliveira Otto MC, Kr\u00f6ger J, Qureshi W, Virtanen JK, Bassett JK, Frazier-Wood AC, Lankinen M, Murphy RA, Rajaobelina K, Del Gobbo LC, Forouhi NG, Luben R, Khaw KT, Wareham N, Kalsbeek A, Veenstra J, Luo J, Hu FB, Lin HJ, Siscovick DS, Boeing H, Chen TA, Steffen B, Steffen LM, Hodge A, Eriksdottir G, Smith AV, Gudnason V, Harris TB, Brouwer IA, Berr C, Helmer C, Samieri C, Laakso M, Tsai MY, Giles GG, Nurmi T, Wagenknecht L, Schulze MB, Lemaitre RN, Chien KL, Soedamah-Muthu SS, Geleijnse JM, Sun Q, Harris WS, Lind L, \u00c4rnl\u00f6v J, Riserus U, Micha R, Mozaffarian D; Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Fatty Acids and Outcomes Research Consortium (FORCE). <strong>Omega-6 fatty acid biomarkers and incident type 2 diabetes: pooled analysis of individual-level data for 39\u2008740 adults from 20 prospective cohort studies<\/strong>. Lancet Diabetes Endocrinol. 2017;5(12):965-974. Epub 2017 Oct 12<\/p>\n<p>Zhang X, Norton J, Carri\u00e8re I, Ritchie K, Chaudieu I, Ryan J, Ancelin ML. <strong>Preliminary evidence for a role of the adrenergic nervous system in generalized anxiety disorder<\/strong>. Sci Rep. 2017;7:42676. doi: 10.1038\/srep42676<\/p>\n<\/div><\/div><\/div><\/div><\/div><style type=\"text\/css\">.fusion-accordian  #accordion-880-17 .panel-title a .fa-fusion-box{ color: #ffffff;}.fusion-accordian  #accordion-880-17 .panel-title a .fa-fusion-box:before{ font-size: 16px; width: 16px;}.fusion-accordian  #accordion-880-17 .panel-title a{font-size:24px;}.fusion-accordian  #accordion-880-17 .fa-fusion-box { background-color: #212934;border-color: #212934;}.fusion-accordian  #accordion-880-17 .panel-title a:hover, #accordion-880-17 .fusion-toggle-boxed-mode:hover .panel-title a { color: #65bc7b;}.fusion-accordian  #accordion-880-17 .panel-title .active .fa-fusion-box,.fusion-accordian  #accordion-880-17 .panel-title a:hover .fa-fusion-box { background-color: #65bc7b!important;border-color: #65bc7b!important;}<\/style><div class=\"accordian fusion-accordian\"><div class=\"panel-group\" id=\"accordion-880-17\"><div class=\"fusion-panel panel-default\"><div class=\"panel-heading\"><h4 class=\"panel-title toggle\"><a aria-expanded=\"false\" aria-controls=\"b62d574be542ad67f\" role=\"button\" data-toggle=\"collapse\" data-parent=\"#accordion-880-17\" data-target=\"#b62d574be542ad67f\" href=\"#b62d574be542ad67f\"><span class=\"fusion-toggle-icon-wrapper\" aria-hidden=\"true\"><i class=\"fa-fusion-box\" aria-hidden=\"true\"><\/i><\/span><span class=\"fusion-toggle-heading\">2018<\/span><\/a><\/h4><\/div><div id=\"b62d574be542ad67f\" class=\"panel-collapse collapse \"><div class=\"panel-body toggle-content fusion-clearfix\">\n<p>Ajana S, Weber D, Helmer C, Merle BM, Stuetz W, Dartigues JF, Rougier MB, Korobelnik JF, Grune T, Delcourt C, F\u00e9art C. <strong>Plasma Concentrations of Lutein and Zeaxanthin, Macular Pigment Optical Density, and Their Associations With Cognitive Performances Among Older Adults<\/strong>. Invest Ophthalmol Vis Sci. 2018;59(5):1828-1835.<\/p>\n<p>Brainstorm Consortium, Anttila V, Bulik-Sullivan B, Finucane HK, Walters RK, Bras J, Duncan L, Escott-Price V, Falcone GJ, Gormley P, Malik R, Patsopoulos NA, Ripke S, Wei Z, Yu D, Lee PH, Turley P, Grenier-Boley B, Chouraki V, Kamatani Y, Berr C, Letenneur L, Hannequin D, Amouyel P, Boland A, Deleuze JF, Duron E, Vardarajan BN, Reitz C, Goate AM, Huentelman MJ, Kamboh MI, Larson EB, Rogaeva E, St George-Hyslop P, Hakonarson H, Kukull WA, Farrer LA, Barnes LL, Beach TG, Demirci FY, Head E, Hulette CM, Jicha GA, Kauwe JSK, Kaye JA, Leverenz JB, Levey AI, Lieberman AP, Pankratz VS, Poon WW, Quinn JF, Saykin AJ, Schneider LS, Smith AG, Sonnen JA, Stern RA, Van Deerlin VM, Van Eldik LJ, Harold D, Russo G, Rubinsztein DC, Bayer A, Tsolaki M, Proitsi P, Fox NC, Hampel H, Owen MJ, Mead S, Passmore P, Morgan K, N\u00f6then MM, Rossor M, Lupton MK, Hoffmann P, Kornhuber J, Lawlor B, McQuillin A, Al-Chalabi A, Bis JC, Ruiz A, Boada M, Seshadri S, Beiser A, Rice K, van der Lee SJ, De Jager PL, Geschwind DH, Riemenschneider M, Riedel-Heller S, Rotter JI, Ransmayr G, Hyman BT, Cruchaga C, Alegret M, Winsvold B, Palta P, Farh KH, Cuenca-Leon E, Furlotte N, Kurth T, Ligthart L, Terwindt GM, Freilinger T, Ran C, Gordon SD, Borck G, Adams HHH, Lehtim\u00e4ki T, Wedenoja J, Buring JE, Sch\u00fcrks M, Hrafnsdottir M, Hottenga JJ, Penninx B, Artto V, Kaunisto M, Veps\u00e4l\u00e4inen S, Martin NG, Montgomery GW, Kurki MI, H\u00e4m\u00e4l\u00e4inen E, Huang H, Huang J, Sandor C, Webber C, Muller-Myhsok B, Schreiber S, Salomaa V, Loehrer E, G\u00f6bel H, Macaya A, Pozo-Rosich P, Hansen T, Werge T, Kaprio J, Metspalu A, Kubisch C, Ferrari MD, Belin AC, van den Maagdenberg AMJM, Zwart JA, Boomsma D, Eriksson N, Olesen J, Chasman DI, Nyholt DR, Avbersek A, Baum L, Berkovic S, Bradfield J, Buono R, Catarino CB, Cossette P, De Jonghe P, Depondt C, Dlugos D, Ferraro TN, French J, Hjalgrim H, Jamnadas-Khoda J, K\u00e4lvi\u00e4inen R, 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M, Levitt P, Maestrini E, Mane S, De-Luca DM, Parr J, Regan R, Reichenberg A, Sandin S, Vorstman J, Wassink T, Wijsman E, Cook E, Santangelo S, Delorme R, Rog\u00e9 B, Magalhaes T, Arking D, Schulze TG, Thompson RC, Strohmaier J, Matthews K, Melle I, Morris D, Blackwood D, McIntosh A, Bergen SE, Schalling M, Jamain S, Maaser A, Fischer SB, Reinbold CS, Fullerton JM, Guzman-Parra J, Mayoral F, Schofield PR, Cichon S, M\u00fchleisen TW, Degenhardt F, Schumacher J, Bauer M, Mitchell PB, Gershon ES, Rice J, Potash JB, Zandi PP, Craddock N, Ferrier IN, Alda M, Rouleau GA, Turecki G, Ophoff R, Pato C, Anjorin A, Stahl E, Leber M, Czerski PM, Cruceanu C, Jones IR, Posthuma D, Andlauer TFM, Forstner AJ, Streit F, Baune BT, Air T, Sinnamon G, Wray NR, MacIntyre DJ, Porteous D, Homuth G, Rivera M, Grove J, Middeldorp CM, Hickie I, Pergadia M, Mehta D, Smit JH, Jansen R, de Geus E, Dunn E, Li QS, Nauck M, Schoevers RA, Beekman AT, Knowles JA, Viktorin A, Arnold P, Barr CL, Bedoya-Berrio G, Bienvenu OJ, Brentani H, Burton C, Camarena B, Cappi C, Cath D, Cavallini M, Cusi D, Darrow S, Denys D, Derks EM, Dietrich A, Fernandez T, Figee M, Freimer N, Gerber G, Grados M, Greenberg E, Hanna GL, Hartmann A, Hirschtritt ME, Hoekstra PJ, Huang A, Huyser C, Illmann C, Jenike M, Kuperman S, Leventhal B, Lochner C, Lyon GJ, Macciardi F, Madruga-Garrido M, Malaty IA, Maras A, McGrath L, Miguel EC, Mir P, Nestadt G, Nicolini H, Okun MS, Pakstis A, Paschou P, Piacentini J, Pittenger C, Plessen K, Ramensky V, Ramos EM, Reus V, Richter MA, Riddle MA, Robertson MM, Roessner V, Ros\u00e1rio M, Samuels JF, Sandor P, Stein DJ, Tsetsos F, Van Nieuwerburgh F, Weatherall S, Wendland JR, Wolanczyk T, Worbe Y, Zai G, Goes FS, McLaughlin N, Nestadt PS, Grabe HJ, Depienne C, Konkashbaev A, Lanzagorta N, Valencia-Duarte A, Bramon E, Buccola N, Cahn W, Cairns M, Chong SA, Cohen D, Crespo-Facorro B, Crowley J, Davidson M, DeLisi L, Dinan T, Donohoe G, Drapeau E, Duan J, Haan L, Hougaard D, Karachanak-Yankova S, Khrunin A, Klovins J, Ku\u010dinskas V, Lee Chee Keong J, Limborska S, Loughland C, L\u00f6nnqvist J, Maher B, Mattheisen M, McDonald C, Murphy KC, Nenadic I, van Os J, Pantelis C, Pato M, Petryshen T, Quested D, Roussos P, Sanders AR, Schall U, Schwab SG, Sim K, So HC, St\u00f6gmann E, Subramaniam M, Toncheva D, Waddington J, Walters J, Weiser M, Cheng W, Cloninger R, Curtis D, Gejman PV, Henskens F, Mattingsdal M, Oh SY, Scott R, Webb B, Breen G, Churchhouse C, Bulik CM, Daly M, Dichgans M, Faraone SV, Guerreiro R, Holmans P, Kendler KS, Koeleman B, Mathews CA, Price A, Scharf J, Sklar P, Williams J, Wood NW, Cotsapas C, Palotie A, Smoller JW, Sullivan P, Rosand J, Corvin A, Neale BM, Schott JM, Anney R, Elia J, Grigoroiu-Serbanescu M, Edenberg HJ, Murray R. <strong>Analysis of shared heritability in common disorders of the brain<\/strong>. Science. 2018 Jun 22;360(6395). pii: eaap8757. doi: 10.1126\/science.aap8757<\/p>\n<p>Arnould L, Binquet C, Guenancia C, Alassane S, Kawasaki R, Daien V, Tzourio C, Kawasaki Y, Bourredjem A, Bron A, Creuzot-Garcher C. <strong>Association between the retinal vascular network with Singapore \u00ab\u00a0I\u00a0\u00bb Vessel Assessment (SIVA) software, cardiovascular history and risk factors in the elderly: The Montrachet study, population-based study<\/strong>. PLoS One. 2018;13(4):e0194694. eCollection 2018.<\/p>\n<p>Bensassi I, Lopez-Castroman J, Maller JJ, Meslin C, Wyart M, Ritchie K, Courtet P, Artero S, Calati R. <strong>Smaller hippocampal volume in current but not in past depression in comparison to healthy controls: Minor evidence from an older adults sample.<\/strong> J Psychiatr Res. 2018;102:159-167. Epub 2018 Apr 9<\/p>\n<p>Bis JC, Jian X, Kunkle BW, Chen Y, Hamilton-Nelson KL, Bush WS, Salerno WJ, Lancour D, Ma Y, Renton AE, Marcora E, Farrell JJ, Zhao Y, Qu L, Ahmad S, Amin N, Amouyel P, Beecham GW, Below JE, Campion D, Charbonnier C, Chung J, Crane PK, Cruchaga C, Cupples LA, Dartigues JF, Debette S, Deleuze JF, Fulton L, Gabriel SB, Genin E, Gibbs RA, Goate A, Grenier-Boley B, Gupta N, Haines JL, Havulinna AS, Helisalmi S, Hiltunen M, Howrigan DP, Ikram MA, Kaprio J, Konrad J, Kuzma A, Lander ES, Lathrop M, Lehtim\u00e4ki T, Lin H, Mattila K, Mayeux R, Muzny DM, Nasser W, Neale B, Nho K, Nicolas G, Patel D, Pericak-Vance MA, Perola M, Psaty BM, Quenez O, Rajabli F, Redon R, Reitz C, Remes AM, Salomaa V, Sarnowski C, Schmidt H, Schmidt M, Schmidt R, Soininen H, Thornton TA, Tosto G, Tzourio C, van der Lee SJ, van Duijn CM, Vardarajan B, Wang W, Wijsman E, Wilson RK, Witten D, Worley KC, Zhang X; Alzheimer\u2019s Disease Sequencing Project, Bellenguez C, Lambert JC, Kurki MI, Palotie A, Daly M, Boerwinkle E, Lunetta KL, Destefano AL, Dupuis J, Martin ER, Schellenberg GD, Seshadri S, Naj AC, Fornage M, Farrer LA. <strong>Whole exome sequencing study identifies novel rare and common Alzheimer&rsquo;s-Associated variants involved in immune response and transcriptional regulation<\/strong>. Mol Psychiatry. 2018 Aug 14. doi: 10.1038\/s41380-018-0112-7.\u00a0<\/p>\n<p>Butcher L, P\u00e9r\u00e8s K, Andr\u00e9 P, Morris RH, Walter S, Dartigues JF, Rodriguez-Ma\u00f1as L, Feart C, Erusalimsky JD; FRAILOMIC consortium. <strong>Association between plasma CCL11 (eotaxin-1) and cognitive status in older adults: Differences between rural and urban dwellers<\/strong>. Exp Gerontol. 2018;113:173-179. Epub 2018 Oct 9<\/p>\n<p>Calati R, Maller JJ, Meslin C, Lopez-Castroman J, Ritchie K, Courtet P, Artero S. <strong>Repatriation is associated with isthmus cingulate cortex reduction in community-dwelling elderly<\/strong>. World J Biol Psychiatry. 2018;19(6):421-430. Epub 2016 Dec 15<\/p>\n<p>Cosh S, Na\u00ebl V, Carri\u00e8re I, Daien V, Amieva H, Delcourt C, Helmer C, The Sense-Cog Consortium. <strong>Bidirectional associations of vision and hearing loss with anxiety: prospective findings from the Three-City Study<\/strong>. Age Ageing. 2018;47(4):582-589<\/p>\n<p>Cosh S, Carriere I, Daien V, Amieva H, Tzourio C, Delcourt C, Helmer C; Sense-Cog Consortium. <strong>The relationship between hearing loss in older adults and depression over 12 years: Findings from the Three-City prospective cohort study<\/strong>. Int J Geriatr Psychiatry. 2018 Dec;33(12):1654-1661. Epub 2018 Sep 13<\/p>\n<p>Culverhouse RC, Saccone NL, Horton AC, Ma Y, Anstey KJ, Banaschewski T, Burmeister M, Cohen-Woods S, Etain B, Fisher HL, Goldman N, Guillaume S, Horwood J, Juhasz G, Lester KJ, Mandelli L, Middeldorp CM, Oli\u00e9 E, Villafuerte S, Air TM, Araya R, Bowes L, Burns R, Byrne EM, Coffey C, Coventry WL, Gawronski KAB, Glei D, Hatzimanolis A, Hottenga JJ, Jaussent I, Jawahar C, Jennen-Steinmetz C, Kramer JR, Lajnef M, Little K, Zu Schwabedissen HM, Nauck M, Nederhof E, Petschner P, Peyrot WJ, Schwahn C, Sinnamon G, Stacey D, Tian Y, Toben C, Van der Auwera S, Wainwright N, Wang JC, Willemsen G, Anderson IM, Arolt V, \u00c5slund C, Bagdy G, Baune BT, Bellivier F, Boomsma DI, Courtet P, Dannlowski U, de Geus EJC, Deakin JFW, Easteal S, Eley T, Fergusson DM, Goate AM, Gonda X, Grabe HJ, Holzman C, Johnson EO, Kennedy M, Laucht M, Martin NG, Munaf\u00f2 MR, Nilsson KW, Oldehinkel AJ, Olsson CA, Ormel J, Otte C, Patton GC, Penninx BWJH, Ritchie K, Sarchiapone M, Scheid JM, Serretti A, Smit JH, Stefanis NC, Surtees PG, V\u00f6lzke H, Weinstein M, Whooley M, Nurnberger JI Jr, Breslau N, Bierut LJ. <strong>Collaborative meta-analysis finds no evidence of a strong interaction between stress and 5-HTTLPR genotype contributing to the development of depression<\/strong>. Mol Psychiatry. 2018;23(1):133-142. Epub 2017 Apr 4<\/p>\n<p>Danet-Lamasou M, P\u00e9r\u00e8s K, Matharan F, Berr C, Carri\u00e8re I, Tzourio C, Delcourt C, Bourdel-Marchasson I.<strong> Near Visual Impairment Incidence in Relation to Diabetes in Older People: The Three-Cities Study<\/strong>. J Am Geriatr Soc. 2018;66(4):699-705. Epub 2018 Jan 18<\/p>\n<p>Davies G, Lam M, Harris SE, Trampush JW, Luciano M, Hill WD, Hagenaars SP, Ritchie SJ, Marioni RE, Fawns-Ritchie C, Liewald DCM, Okely JA, Ahola-Olli AV, Barnes CLK, Bertram L, Bis JC, Burdick KE, Christoforou A, DeRosse P, Djurovic S, Espeseth T, Giakoumaki S, Giddaluru S, Gustavson DE, Hayward C, Hofer E, Ikram MA, Karlsson R, Knowles E, Lahti J, Leber M, Li S, Mather KA, Melle I, Morris D, Oldmeadow C, Palviainen T, Payton A, Pazoki R, Petrovic K, Reynolds CA, Sargurupremraj M, Scholz M, Smith JA, Smith AV, Terzikhan N, Thalamuthu A, Trompet S, van der Lee SJ, Ware EB, Windham BG, Wright MJ, Yang J, Yu J, Ames D, Amin N, Amouyel P, Andreassen OA, Armstrong NJ, Assareh AA, Attia JR, Attix D, Avramopoulos D, Bennett DA, B\u00f6hmer AC, Boyle PA, Brodaty H, Campbell H, Cannon TD, Cirulli ET, Congdon E, Conley ED, Corley J, Cox SR, Dale AM, Dehghan A, Dick D, Dickinson D, Eriksson JG, Evangelou E, Faul JD, Ford I, Freimer NA, Gao H, Giegling I, Gillespie NA, Gordon SD, Gottesman RF, Griswold ME, Gudnason V, Harris TB, Hartmann AM, Hatzimanolis A, Heiss G, Holliday EG, Joshi PK, K\u00e4h\u00f6nen M, Kardia SLR, Karlsson I, Kleineidam L, Knopman DS, Kochan NA, Konte B, Kwok JB, Le Hellard S, Lee T, Lehtim\u00e4ki T, Li SC, Liu T, Koini M, London E, Longstreth WT Jr, Lopez OL, Loukola A, Luck T, Lundervold AJ, Lundquist A, Lyytik\u00e4inen LP, Martin NG, Montgomery GW, Murray AD, Need AC, Noordam R, Nyberg L, Ollier W, Papenberg G, Pattie A, Polasek O, Poldrack RA, Psaty BM, Reppermund S, Riedel-Heller SG, Rose RJ, Rotter JI, Roussos P, Rovio SP, Saba Y, Sabb FW, Sachdev PS, Satizabal CL, Schmid M, Scott RJ, Scult MA, Simino J, Slagboom PE, Smyrnis N, Soumar\u00e9 A, Stefanis NC, Stott DJ, Straub RE, Sundet K, Taylor AM, Taylor KD, Tzoulaki I, Tzourio C, Uitterlinden A, Vitart V, Voineskos AN, Kaprio J, Wagner M, Wagner H, Weinhold L, Wen KH, Widen E, Yang Q, Zhao W, Adams HHH, Arking DE, Bilder RM, Bitsios P, Boerwinkle E, Chiba-Falek O, Corvin A, De Jager PL, Debette S, Donohoe G, Elliott P, Fitzpatrick AL, Gill M, Glahn DC, H\u00e4gg S, Hansell NK, Hariri AR, Ikram MK, Jukema JW, Vuoksimaa E, Keller MC, Kremen WS, Launer L, Lindenberger U, Palotie A, Pedersen NL, Pendleton N, Porteous DJ, R\u00e4ikk\u00f6nen K, Raitakari OT, Ramirez A, Reinvang I, Rudan I, Dan Rujescu, Schmidt R, Schmidt H, Schofield PW, Schofield PR, Starr JM, Steen VM, Trollor JN, Turner ST, Van Duijn CM, Villringer A, Weinberger DR, Weir DR, Wilson JF, Malhotra A, McIntosh AM, Gale CR, Seshadri S, Mosley TH Jr, Bressler J, Lencz T, Deary IJ.<strong> Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function<\/strong>. Nat Commun. 2018;9(1):2098.<\/p>\n<p>Delcourt C, Le Goff M, von Hanno T, Mirshahi A, Khawaja AP, Verhoeven VJM, Hogg RE, Anastosopoulos E, Cachulo ML, H\u00f6hn R, Wolfram C, Bron A, Miotto S, Carri\u00e8re I, Colijn JM, Buitendijk GHS, Evans J, Nitsch D, Founti P, Yip JLY, Pfeiffer N, Creuzot-Garcher C, Silva R, Piermarocchi S, Topouzis F, Bertelsen G, Foster PJ, Fletcher A, Klaver CCW, Korobelnik JF; European Eye Epidemiology Consortium.<strong> The Decreasing Prevalence of Nonrefractive Visual Impairment in Older Europeans: A Meta-analysis of Published and Unpublished Data<\/strong>. Ophthalmology. 2018;125(8):1149-1159. Epub 2018 Mar 13<\/p>\n<p>Duperron MG, Tzourio C, Sargurupremraj M, Mazoyer B, Soumar\u00e9 A, Schilling S, Amouyel P, Chauhan G, Zhu YC, Debette S. <strong>Burden of Dilated<\/strong> <strong>Perivascular Spaces, an Emerging Marker of Cerebral Small Vessel Disease, Is Highly Heritable<\/strong>. Stroke. 2018;49(2):282-287. 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Epub 2018 Aug 9<\/p>\n<p>Harmand MG, Meillon C, Rullier L, Tadd\u00e9 OB, Pimouguet C, Dartigues JF, Bergua V, Amieva H.<strong> Description of general practitioners&rsquo; practices when suspecting cognitive impairment. Recourse to care in dementia (Recaredem) study<\/strong>. Aging Ment Health. 2018;22(8):1040-1049. Epub 2017 Jun 8<\/p>\n<p>Husson T, Duboc JB, Quenez O, Charbonnier C, Rotharmel M, Cuenca M, Jegouzo X, Richard AC, Frebourg T, Deleuze JF, Boland A, Genin E, Debette S, Tzourio C, Campion D, Nicolas G, Guillin O; FREX Consortium. <strong>Identification of potential genetic risk factors for bipolar disorder by whole-exome sequencing<\/strong>. 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Howson JMM, Kamatani Y, Debette S, Dichgans M, Malik R, Chauhan G, Traylor M, Sargurupremraj M, Okada Y, Mishra A, Rutten-Jacobs L, Giese AK, van der Laan SW, Gretarsdottir S, Anderson CD, Chong M, Adams HHH, Ago T, Almgren P, Amouyel P, Ay H, Bartz TM, Benavente OR, Bevan S, Boncoraglio GB, Brown RD Jr, Butterworth AS, Carrera C, Carty CL, Chasman DI, Chen WM, Cole JW, Correa A, Cotlarciuc I, Cruchaga C, Danesh J, de Bakker PIW, DeStefano AL, Hoed MD, Duan Q, Engelter ST, Falcone GJ, Gottesman RF, Grewal RP, Gudnason V, Gustafsson S, Haessler J, Harris TB, Hassan A, Havulinna AS, Heckbert SR, Holliday EG, Howard G, Hsu FC, Hyacinth HI, Ikram MA, Ingelsson E, Irvin MR, Jian X, Jim\u00e9nez-Conde J, Johnson JA, Jukema JW, Kanai M, Keene KL, Kissela BM, Kleindorfer DO, Kooperberg C, Kubo M, Lange LA, Langefeld CD, Langenberg C, Launer LJ, Lee JM, Lemmens R, Leys D, Lewis CM, Lin WY, Lindgren AG, Lorentzen E, Magnusson PK, Maguire J, Manichaikul A, McArdle PF, Meschia JF, Mitchell BD, Mosley TH, Nalls MA, Ninomiya T, O&rsquo;Donnell MJ, Psaty BM, Pulit SL, Rannikm\u00e4e K, Reiner AP, Rexrode KM, Rice K, Rich SS, Ridker PM, Rost NS, Rothwell PM, Rotter JI, Rundek T, Sacco RL, Sakaue S, Sale MM, Salomaa V, Sapkota BR, Schmidt R, Schmidt CO, Schminke U, Sharma P, Slowik A, Sudlow CLM, Tanislav C, Tatlisumak T, Taylor KD, Thijs VNS, Thorleifsson G, Thorsteinsdottir U, Tiedt S, Trompet S, Tzourio C, van Duijn CM, Walters M, Wareham NJ, Wassertheil-Smoller S, Wilson JG, Wiggins KL, Yang Q, Yusuf S, Amin N, Aparicio HS, Arnett DK, Attia J, Beiser AS, Berr C, Buring JE, Bustamante M, Caso V, Cheng YC, Choi SH, Chowhan A, Cullell N, Dartigues JF, Delavaran H, Delgado P, D\u00f6rr M, Engstr\u00f6m G, Ford I, Gurpreet WS, Hamsten A, Heitsch L, Hozawa A, Ibanez L, Ilinca A, Ingelsson M, Iwasaki M, Jackson RD, Jood K, Jousilahti P, Kaffashian S, Kalra L, Kamouchi M, Kitazono T, Kjartansson O, Kloss M, Koudstaal PJ, Krupinski J, Labovitz DL, Laurie CC, Levi CR, Li L, Lind L, Lindgren CM, Lioutas V, Liu YM, Lopez OL, Makoto H, Martinez-Majander N, Matsuda K, Minegishi N, Montaner J, Morris AP, Mui\u00f1o E, M\u00fcller-Nurasyid M, Norrving B, Ogishima S, Parati EA, Peddareddygari LR, Pedersen NL, Pera J, Perola M, Pezzini A, Pileggi S, Rabionet R, Riba-Llena I, Ribas\u00e9s M, Romero JR, Roquer J, Rudd AG, Sarin AP, Sarju R, Sarnowski C, Sasaki M, Satizabal CL, Satoh M, Sattar N, Sawada N, Sibolt G, Sigurdsson \u00c1, Smith A, Sobue K, Soriano-T\u00e1rraga C, Stanne T, Stine OC, Stott DJ, Strauch K, Takai T, Tanaka H, Tanno K, Teumer A, Tomppo L, Torres-Aguila NP, Touze E, Tsugane S, Uitterlinden AG, Valdimarsson EM, van der Lee SJ, V\u00f6lzke H, Wakai K, Weir D, Williams SR, Wolfe CDA, Wong Q, Xu H, Yamaji T, Sanghera DK, Melander O, Jern C, Strbian D, Fernandez-Cadenas I, Longstreth WT Jr, Rolfs A, Hata J, Woo D, Rosand J, Pare G, Hopewell JC, Saleheen D, Stefansson K, Worrall BB, Kittner SJ, Seshadri S, Fornage M, Markus HS, Howson JMM, Kamatani Y, Debette S, Dichgans M; AFGen Consortium; Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium; International Genomics of Blood Pressure (iGEN-BP) Consortium; INVENT Consortium; STARNET; BioBank Japan Cooperative Hospital Group; COMPASS Consortium; EPIC-CVD Consortium; EPIC-InterAct Consortium; International Stroke Genetics Consortium (ISGC); METASTROKE Consortium; Neurology Working Group of the CHARGE Consortium; NINDS Stroke Genetics Network (SiGN); UK Young Lacunar DNA Study; MEGASTROKE Consortium; MEGASTROKE Consortium. <strong>Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtype<\/strong>s. Nat Genet. 2018;50(4):524-537. Epub 2018 Mar 12<\/p>\n<p>Malik R, Rannikm\u00e4e K, Traylor M, Georgakis MK, Sargurupremraj M, Markus HS, Hopewell JC, Debette S, Sudlow CLM, Dichgans M; MEGASTROKE consortium and the International Stroke Genetics Consortium.<strong> Genome-wide meta-analysis identifies 3 novel loci associated with stroke<\/strong>. Ann Neurol. 2018;84(6):934-939. Epub 2018 Nov 30<\/p>\n<p>Mauschitz MM, Bonnemaijer PWM, Diers K, Rauscher FG, Elze T, Engel C, Loeffler M, Colijn JM, Ikram MA, Vingerling JR, Williams KM, Hammond CJ, Creuzot-Garcher C, Bron AM, Silva R, Nunes S, Delcourt C, Cougnard-Gr\u00e9goire A, Holz FG, Klaver CCW, Breteler MMB, Finger RP; European Eye Epidemiology (E3) Consortium. <strong>Systemic and Ocular Determinants of Peripapillary Retinal Nerve Fiber Layer Thickness Measurements in the European Eye Epidemiology (E3) Population<\/strong>. Ophthalmology. 2018;125(10):1526-1536. Epub 2018 Apr 30<\/p>\n<p>Meijers-Heijboer H, van Leeuwen EM, Iyengar SK, Lass JH, Hofman A, Rivadeneira F, Uitterlinden AG, Vingerling JR, Lehtim\u00e4ki T, Raitakari OT, Biino G, Concas MP, Schwantes-An TH, Igo RP Jr, Cuellar-Partida G, Martin NG, Craig JE, Gharahkhani P, Williams KM, Nag A, Rahi JS, Cumberland PM, Delcourt C, Bellenguez C, Ried JS, Bergen AA, Meitinger T, Gieger C, Wong TY, Hewitt AW, Mackey DA, Simpson CL, Pfeiffer N, P\u00e4rssinen O, Baird PN, Vitart V, Amin N, van Duijn CM, Bailey-Wilson JE, Young TL, Saw SM, Stambolian D, MacGregor S, Guggenheim JA, Tung JY, Hammond CJ, Klaver CCW. <strong>Genome-wide association meta-analysis highlights light-induced signaling as a driver for refractive error<\/strong>. Nat Genet. 2018;50(6):834-848. Epub 2018 May 28.<\/p>\n<p>M\u00e9ndez-G\u00f3mez JL, Pelletier A, Rougier MB, Korobelnik JF, Schweitzer C, Delyfer MN, Catheline G, Monferm\u00e9 S, Dartigues JF, Delcourt C, Helmer C. <strong>Association of Retinal Nerve Fiber Layer Thickness With Brain Alterations in the Visual and Limbic Networks in Elderly Adults Without Dementia<\/strong>. JAMA Netw Open. 2018;1(7):e184406.<\/p>\n<p>Mortamais M, Abdennour M, Bergua V, Tzourio C, Berr C, Gabelle A, Akbaraly TN.<strong> Anxiety and 10-Year Risk of Incident Dementia-An Association Shaped by Depressive Symptoms: Results of the Prospective Three-City Study<\/strong>. Front Neurosci. 2018;12:248. eCollection 201<\/p>\n<p>NCD Risk Factor Collaboration (NCD-RisC). <strong>Contributions of mean and shape of blood pressure distribution to worldwide trends and variations in raised blood pressure: a pooled analysis of 1018 population-based measurement studies with 88.6 million participants<\/strong>. Int J Epidemiol. 2018 Mar 19. doi: 10.1093\/ije\/dyy016.<\/p>\n<p>Olson NC, Raffield LM, Lange LA, Lange EM, Longstreth WT Jr, Chauhan G, Debette S, Seshadri S, Reiner AP, Tracy RP. <strong>Associations of activated coagulation factor VII and factor VIIa-antithrombin levels with genome-wide polymorphisms and cardiovascular disease risk<\/strong>. J Thromb Haemost. 2018;16(1):19-30. Epub 2017 Dec 8<\/p>\n<p>Peloso GM, van der Lee SJ; International Genomics of Alzheimer&rsquo;s Project (IGAP), Destefano AL, Seshardi S. <strong>Genetically elevated high-density lipoprotein cholesterol through the cholesteryl ester transfer protein gene does not associate with risk of Alzheimer&rsquo;s disease<\/strong>. Alzheimers Dement (Amst). 2018;10:595-598<\/p>\n<p>Pilleron S, P\u00e9r\u00e8s K, Jutand MA, Helmer C, Dartigues JF, Samieri C, F\u00e9art C. <strong>Dietary patterns and risk of self-reported activity limitation in older adults from the Three-City Bordeaux Study<\/strong>. Br J Nutr. 2018;120(5):549-556. Epub 2018 Jul 10<\/p>\n<p>Rahi B, Ajana S, Tabue-Teguo M, Dartigues JF, Peres K, Feart C. <strong>High adherence to a Mediterranean diet and lower risk of frailty among French older adults community-dwellers: Results from the Three-City-Bordeaux Study<\/strong>. Clin Nutr. 2018;37(4):1293-1298.. Epub 2017 May 31<\/p>\n<p>Rullier L, Meillon C, Bergua V, Pimouguet C, Gonzalez-Cola\u00e7o Harmand M, Helmer C, P\u00e9r\u00e8s K, Dartigues JF, Amieva H. <strong>A comprehensive approach of the determinants of use of care in dementia: the Recaredem (recourse to care in dementia) cross-sectional study<\/strong>. Int Psychogeriatr. 2018:1-11. doi: 10.1017\/S1041610218001497.\u00a0<\/p>\n<p>Samieri C, Morris MC, Bennett DA, Berr C, Amouyel P, Dartigues JF, Tzourio C, Chasman DI, Grodstein F. <strong>Fish Intake, Genetic Predisposition to Alzheimer Disease, and Decline in Global Cognition and Memory in 5 Cohorts of Older Persons<\/strong>. Am J Epidemiol. 2018;187(5):933-940<\/p>\n<p>Samieri C, Perier MC, Gaye B, Proust-Lima C, Helmer C, Dartigues JF, Berr C, Tzourio C, Empana JP.<strong> Association of Cardiovascular Health Level in Older Age With Cognitive Decline and Incident Dementia<\/strong>. JAMA. 2018;320(7):657-664.<\/p>\n<p>Satizabal CL, Samieri C, Davis-Plourde KL, Voetsch B, Aparicio HJ, Pase MP, Romero JR, Helmer C, Vasan RS, Kase CS, Debette S, Beiser AS, Seshadri S. <strong>APOE and the Association of Fatty Acids With the Risk of Stroke, Coronary Heart Disease, and Mortality<\/strong>. Stroke. 2018;49(12):2822-2829.<\/p>\n<p>Saunier V, Merle BMJ, Delyfer MN, Cougnard-Gr\u00e9goire A, Rougier MB, Amouyel P, Lambert JC, Dartigues JF, Korobelnik JF, Delcourt C. <strong>Incidence of and Risk Factors Associated With Age-Related Macular Degeneration: Four-Year Follow-up From the ALIENOR Study<\/strong>. JAMA Ophthalmol. 2018;136(5):473-481.<\/p>\n<p>Schweitzer C, Cougnard-Gregoire A, Rigalleau V, Dartigues JF, Malet F, Rougier MB, Delyfer MN, Helmer C, Korobelnik JF, Delcourt C. <strong>Autofluorescence of Skin Advanced Glycation End Products as a Risk Factor for Open Angle Glaucoma: The ALIENOR Study<\/strong>. Invest Ophthalmol Vis Sci. 2018;59(1):75-84<\/p>\n<p>Tedja MS, Wojciechowski R, Hysi PG, Eriksson N, Furlotte NA, Verhoeven VJM, Iglesias AI, Meester-Smoor MA, Tompson SW, Fan Q, Khawaja AP, Cheng CY, H\u00f6hn R, Yamashiro K, Wenocur A, Grazal C, Haller T, Metspalu A, Wedenoja J, Jonas JB, Wang YX, Xie J, Mitchell P, Foster PJ, Klein BEK, Klein R, Paterson AD, Hosseini SM, Shah RL, Williams C, Teo YY, Tham YC, Gupta P, Zhao W, Shi Y, Saw WY, Tai ES, Sim XL, Huffman JE, Pola\u0161ek O, Hayward C, Bencic G, Rudan I, Wilson JF; CREAM Consortium; 23andMe Research Team; UK Biobank Eye and Vision Consortium, Joshi PK, Tsujikawa A, Matsuda F, Whisenhunt KN, Zeller T, van der Spek PJ, Haak R, Meijers-Heijboer H, van Leeuwen EM, Iyengar SK, Lass JH, Hofman A, Rivadeneira F, Uitterlinden AG, Vingerling JR, Lehtim\u00e4ki T, Raitakari OT, Biino G, Concas MP, Schwantes-An TH, Igo RP Jr, Cuellar-Partida G, Martin NG, Craig JE, Gharahkhani P, Williams KM, Nag A, Rahi JS, Cumberland PM, Delcourt C, Bellenguez C, Ried JS, Bergen AA, Meitinger T, Gieger C, Wong TY, Hewitt AW, Mackey DA, Simpson CL, Pfeiffer N, P\u00e4rssinen O, Baird PN, Vitart V, Amin N, van Duijn CM, Bailey-Wilson JE, Young TL, Saw SM, Stambolian D, MacGregor S, Guggenheim JA, Tung JY, Hammond CJ, Klaver CCW. Genome-wide association meta-analysis highlights light-induced signaling as a driver for refractive error. Nat Genet. 2018;50(6):834-848. Epub 2018 May 28<\/p>\n<p>Tully PJ, Debette S, Tzourio C. <strong>The association between systolic blood pressure variability with depression, cognitive decline and white matter hyperintensities: the 3C Dijon MRI study<\/strong>. Psychol Med. 2018;48(9):1444-1453. Epub 2017 Sep 27<\/p>\n<p>Tully PJ, Peters R, P\u00e9r\u00e8s K, Anstey KJ, Tzourio C. <strong>Effect of SSRI and calcium channel blockers on depression symptoms and cognitive function in elderly persons treated for hypertension: three city cohort study<\/strong>. Int Psychogeriatr. 2018;30(9):1345-1354. Epub 2018 Mar 21.<\/p>\n<p>Tully PJ, Turnbull DA, Anstey KJ, Beckett N, Beiser AS, Birns J, Brickman AM, Burns NR, Cosh S, de Leeuw PW, Dorstyn D, Elias MF, Wouter Jukema J, Kario K, Kikuya M, Kroon AA, Launer LJ, Mahajan R, McGrath ER, Mooijaart SP, Moll van Charante EP, Nagai M, Ninomiya T, Ohara T, Ohkubo T, Oishi E, Peters R, Richard E, Satoh M, Seshadri S, Stott DJ, van Gool WA, van Middelaar T, Trompet S, Giles K, Drioli-Phillips P, Aaimir U, Connolly F, Tzourio C. VARIABLE BRAIN consortium. <strong>The association between blood pressure variability (BPV) with dementia and cognitive function: a systematic review and meta-analysis protocol<\/strong>. Syst Rev. 2018;7(1):163<\/p>\n<p>54. Wagner M, Dartigues JF, Samieri C, Proust-Lima C. <strong>Modeling Risk-Factor Trajectories When Measurement Tools Change Sequentially During Follow-up in Cohort Studies: Application to Dietary Habits in Prodromal Dementia<\/strong>. Am J Epidemiol. 2018;187(4):845-854.<\/p>\n<p>Wagner M, Helmer C, Tzourio C, Berr C, Proust-Lima C, Samieri C. <strong>Evaluation of the Concurrent Trajectories of Cardiometabolic Risk Factors in the 14 Years Before Dementia<\/strong>.JAMA Psychiatry. 2018;75(10):1033-1042.<\/p>\n<p>Zhu D, Chung HF, Pandeya N, Dobson AJ, Cade JE, Greenwood DC, Crawford SL, Avis NE, Gold EB, Mitchell ES, Woods NF, Anderson D, Brown DE, Sievert LL, Brunner EJ, Kuh D, Hardy R, Hayashi K, Lee JS, Mizunuma H, Giles GG, Bruinsma F, Tillin T, Simonsen MK, Adami HO, Weiderpass E, Canonico M, Ancelin ML, Demakakos P, Mishra GD. <strong>Relationships between intensity, duration, cumulative dose, and timing of smoking with age at menopause: A pooled analysis of individual data from 17 observational studies<\/strong>. PLoS Med. 2018;15(11):e1002704. eCollection 2018 Nov<\/p>\n<\/div><\/div><\/div><\/div><\/div><style type=\"text\/css\">.fusion-accordian  #accordion-880-18 .panel-title a .fa-fusion-box{ color: #ffffff;}.fusion-accordian  #accordion-880-18 .panel-title a .fa-fusion-box:before{ font-size: 16px; width: 16px;}.fusion-accordian  #accordion-880-18 .panel-title a{font-size:24px;}.fusion-accordian  #accordion-880-18 .fa-fusion-box { background-color: #212934;border-color: #212934;}.fusion-accordian  #accordion-880-18 .panel-title a:hover, #accordion-880-18 .fusion-toggle-boxed-mode:hover .panel-title a { color: #65bc7b;}.fusion-accordian  #accordion-880-18 .panel-title .active .fa-fusion-box,.fusion-accordian  #accordion-880-18 .panel-title a:hover .fa-fusion-box { background-color: #65bc7b!important;border-color: #65bc7b!important;}<\/style><div class=\"accordian fusion-accordian\"><div class=\"panel-group\" id=\"accordion-880-18\"><div class=\"fusion-panel panel-default\"><div class=\"panel-heading\"><h4 class=\"panel-title toggle\"><a aria-expanded=\"false\" aria-controls=\"d3398d60de0614211\" role=\"button\" data-toggle=\"collapse\" data-parent=\"#accordion-880-18\" data-target=\"#d3398d60de0614211\" href=\"#d3398d60de0614211\"><span class=\"fusion-toggle-icon-wrapper\" aria-hidden=\"true\"><i class=\"fa-fusion-box\" aria-hidden=\"true\"><\/i><\/span><span class=\"fusion-toggle-heading\">2019<\/span><\/a><\/h4><\/div><div id=\"d3398d60de0614211\" class=\"panel-collapse collapse \"><div class=\"panel-body toggle-content fusion-clearfix\">\n<p>Ajana S, Acar N, Bretillon L, Hejblum BP, Jacqmin-Gadda H, Delcourt C; BLISAR Study Group. <strong>Benefits of dimension reduction in penalized regression methods for high-dimensional grouped data: a case study in low sample size<\/strong>. Bioinformatics. 2019;35(19):3628-3634.<\/p>\n<p>All\u00e8s B, Samieri C, Jutand MA, Carmichael PH, Shatenstein B, Gaudreau P, Ferland G, Barberger-Gateau P, Laurin D. <strong>Nutrient Patterns, Cognitive Function, and Decline in Older Persons: Results from the Three-City and NuAge Studies<\/strong>. Nutrients. 2019;11(8). pii: E1808. doi: 10.3390\/nu11081808.<\/p>\n<p>Ancelin ML, Carri\u00e8re I, Artero S, Maller J, Meslin C, Ritchie K, Ryan J, Chaudieu I. <strong>Lifetime major depression and grey-matter volume<\/strong>. J Psychiatry Neurosci. 2019;44(1):45-53<\/p>\n<p>Andr\u00e9 P, Samieri C, Buisson C, Dartigues JF, Helmer C, Laugerette F, F\u00e9art C. <strong>Lipopolysaccharide-Binding Protein, Soluble CD14, and the Long-Term Risk of Alzheimer&rsquo;s Disease: A Nested Case-Control Pilot Study of Older Community Dwellers from the Three-City Cohort<\/strong>. J Alzheimers Dis. 2019;71(3):751-761.<\/p>\n<p>Arnould L, Seydou A, Gabrielle PH, Guenancia C, Tzourio C, Bourredjem A, El Alami Y, Daien V, Binquet C, Bron AM, Creuzot-Garcher C.<strong> Subfoveal Choroidal Thickness, Cardiovascular History, and Risk Factors in the Elderly: The Montrachet Study<\/strong>. Invest Ophthalmol Vis Sci. 2019;60(7):2431-2437<\/p>\n<p>Baker E, Sims R, Leonenko G, Frizzati A, Harwood JC, Grozeva D; GERAD\/PERADES; CHARGE; ADGC; EADI; IGAP consortia, Morgan K, Passmore P, Holmes C, Powell J, Brayne C, Gill M, Mead S, Boss\u00f9 P, Spalletta G, Goate AM, Cruchaga C, Maier W, Heun R, Jessen F, Peters O, Dichgans M, Fr\u00f6Lich L, Ramirez A, Jones L, Hardy J, Ivanov D, Hill M, Holmans P, Allen ND, Morgan BP, Seshadri S, Schellenberg GD, Amouyel P, Williams J, Escott-Price V. <strong>Gene-based analysis in HRC imputed genome wide association data identifies three novel genes for Alzheimer&rsquo;s disease<\/strong>. PLoS One. 2019;14(7):e0218111. eCollection 2019<\/p>\n<p>Blanc J, Seydou A, Ben Ghezala I, Deschasse C, Meillon C, Bron AM, Binquet C, Creuzot-Garcher C. <strong>Vitreomacular Interface Abnormalities and Glaucoma in an Elderly Population (The MONTRACHET Study)<\/strong>. Invest Ophthalmol Vis Sci. 2019;60(6):1996-2002.<\/p>\n<p>Chauhan G, Adams HHH, Satizabal CL, Bis JC, Teumer A, Sargurupremraj M, Hofer E, Trompet S, Hilal S, Smith AV, Jian X, Malik R, Traylor M, Pulit SL, Amouyel P, Mazoyer B, Zhu YC, Kaffashian S, Schilling S, Beecham GW, Montine TJ, Schellenberg GD, Kjartansson O, Gu\u00f0nason V, Knopman DS, Griswold ME, Windham BG, Gottesman RF, Mosley TH, Schmidt R, Saba Y, Schmidt H, Takeuchi F, Yamaguchi S, Nabika T, Kato N, Rajan KB, Aggarwal NT, De Jager PL, Evans DA, Psaty BM, Rotter JI, Rice K, Lopez OL, Liao J, Chen C, Cheng CY, Wong TY, Ikram MK, van der Lee SJ, Amin N, Chouraki V, DeStefano AL, Aparicio HJ, Romero JR, Maillard P, DeCarli C, Wardlaw JM, Hern\u00e1ndez MDCV, Luciano M, Liewald D, Deary IJ, Starr JM, Bastin ME, Mu\u00f1oz Maniega S, Slagboom PE, Beekman M, Deelen J, Uh HW, Lemmens R, Brodaty H, Wright MJ, Ames D, Boncoraglio GB, Hopewell JC, Beecham AH, Blanton SH, Wright CB, Sacco RL, Wen W, Thalamuthu A, Armstrong NJ, Chong E, Schofield PR, Kwok JB, van der Grond J, Stott DJ, Ford I, Jukema JW, Vernooij MW, Hofman A, Uitterlinden AG, van der Lugt A, Wittfeld K, Grabe HJ, Hosten N, von Sarnowski B, V\u00f6lker U, Levi C, Jimenez-Conde J, Sharma P, Sudlow CLM, Rosand J, Woo D, Cole JW, Meschia JF, Slowik A, Thijs V, Lindgren A, Melander O, Grewal RP, Rundek T, Rexrode K, Rothwell PM, Arnett DK, Jern C, Johnson JA, Benavente OR, Wasssertheil-Smoller S, Lee JM, Wong Q, Mitchell BD, Rich SS, McArdle PF, Geerlings MI, van der Graaf Y, de Bakker PIW, Asselbergs FW, Srikanth V, Thomson R, McWhirter R, Moran C, Callisaya M, Phan T, Rutten-Jacobs LCA, Bevan S, Tzourio C, Mather KA, Sachdev PS, van Duijn CM, Worrall BB, Dichgans M, Kittner SJ, Markus HS, Ikram MA, Fornage M, Launer LJ, Seshadri S, Longstreth WT Jr, Debette S; Stroke Genetics Network (SiGN), the International Stroke Genetics Consortium (ISGC), METASTROKE, Alzheimer&rsquo;s Disease Genetics Consortium (ADGC), and the Neurology Working Group of the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium. <strong>Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting<\/strong>. Neurology. 2019 Jan 29; 92(5): e486\u2013e503<\/p>\n<p>Chen Z, Chen JA, Shatunov A, Jones AR, Kravitz SN, Huang AY, Lawrence L, Lowe JK, Lewis CM, Payan CAM, Lieb W, Franke A, Deloukas P, Amouyel P, Tzourio C, Dartigues JF; NNIPPS and BBBIPPS Study Groups, Ludolph A, Bensimon G, Leigh PN, Bronstein JM, Coppola G, Geschwind DH, Al-Chalabi A. <strong>Genome-wide survey of copy number variants finds MAPT duplications in progressive supranuclear palsy<\/strong>. Mov Disord. 2019;34(7):1049-1059. Epub 2019 May 6<\/p>\n<p>Chung J, Marini S, Pera J, Norrving B, Jimenez-Conde J, Roquer J, Fernandez-Cadenas I, Tirschwell DL, Selim M, Brown DL, Silliman SL, Worrall BB, Meschia JF, Demel S, Greenberg SM, Slowik A, Lindgren A, Schmidt R, Traylor M, Sargurupremraj M, Tiedt S, Malik R, Debette S, Dichgans M, Langefeld CD, Woo D, Rosand J, Anderson CD. <strong>Genome-wide association study of cerebral small vessel disease reveals established and novel loci<\/strong>. Brain. 2019 Oct 1;142(10):3176-3189<\/p>\n<p>Colijn JM, den Hollander AI, Demirkan A, Cougnard-Gr\u00e9goire A, Verzijden T, Kersten E, Meester-Smoor MA, Merle BMJ, Papageorgiou G, Ahmad S, Mulder MT, Costa MA, Benlian P, Bertelsen G, Bron AM, Claes B, Creuzot-Garcher C, Erke MG, Fauser S, Foster PJ, Hammond CJ, Hense HW, Hoyng CB, Khawaja AP, Korobelnik JF, Piermarocchi S, Segato T, Silva R, Souied EH, Williams KM, van Duijn CM, Delcourt C, Klaver CCW; European Eye Epidemiology Consortium; EYE-RISK Consortium. <strong>Increased High-Density Lipoprotein Levels Associated with Age-Related Macular Degeneration: Evidence from the EYE-RISK and European Eye Epidemiology Consortia<\/strong>. Ophthalmology. 2019;126(3):393-406. Epub 2018 Oct 10.<\/p>\n<p>Cosh S, Carri\u00e8re I, Daien V, Tzourio C, Delcourt C, Helmer C.<strong> Sensory loss and suicide ideation in older adults: findings from the Three-City cohort study<\/strong>. Int Psychogeriatr. 2019;31(1):139-145. Epub 2018 May 25.<\/p>\n<p>Cosh S, Carriere I, Nael V, Tzourio C, Delcourt C, Helmer C; Sense-Cog Consortium. <strong>The association of vision loss and dimensions of depression over 12 years in older adults: Findings from the Three City study<\/strong>. J Affect Disord. 2019 Jan 15;243:477-484. doi: 10.1016\/j.jad.2018.09.071. Epub 2018 Sep 22<\/p>\n<p>Cyprien F, Courtet P, Maller J, Meslin C, Ritchie K, Ancelin ML, Artero S. <strong>Increased Serum C-reactive Protein and Corpus Callosum Alterations in Older Adults<\/strong>. Aging Dis. 2019;10(2):463-469. eCollection 2019 Apr<\/p>\n<p>Debette S, Schilling S, Duperron MG, Larsson SC, Markus HS.<strong> Clinical Significance of Magnetic Resonance Imaging Markers of Vascular Brain Injury: A Systematic Review and Meta-analysis<\/strong>. JAMA Neurol. 2019;76(1):81-94<\/p>\n<p>Duperron MG, Tzourio C, Schilling S, Zhu YC, Soumar\u00e9 A, Mazoyer B, Debette S. <strong>High dilated perivascular space burden: a new MRI marker for risk of intracerebral hemorrhage<\/strong>. Neurobiol Aging. 2019;84:158-165. Epub 2019 Sep 10<\/p>\n<p>1Fretts AM, Imamura F, Marklund M, Micha R, Wu JHY, Murphy RA, Chien KL, McKnight B, Tintle N, Forouhi NG, Qureshi WT, Virtanen JK, Wong K, Wood AC, Lankinen M, Rajaobelina K, Harris TB, Djouss\u00e9 L, Harris B, Wareham NJ, Steffen LM, Laakso M, Veenstra J, Samieri C, Brouwer IA, Yu CI, Koulman A, Steffen BT, Helmer C, Sotoodehnia N, Siscovick D, Gudnason V; InterAct Consortium, Wagenknecht L, Voutilainen S, Tsai MY, Uusitupa M, Kalsbeek A, Berr C, Mozaffarian D, Lemaitre RN. <strong>Associations of circulating very-long-chain saturated fatty acids and incident type 2 diabetes: a pooled analysis of prospective cohort studies<\/strong>. Am J Clin Nutr. 2019;109(4):1216-1223<\/p>\n<p>Frison E, Dufouil C, Helmer C, Berr C, Auriacombe S, Ch\u00eane G. <strong>Diabetes-Associated Dementia Risk and Competing Risk of Death in the Three-City Study<\/strong>. J Alzheimers Dis. 2019;71(4):1339-1350<\/p>\n<p>Galvin A, Helmer C, Coureau G, Amadeo B, Rainfray M, Soubeyran P, Dartigues JF, P\u00e9r\u00e8s K, Bellera C, Delva F, Mathoulin-P\u00e9lissier S. <strong>Determinants of functional decline in older adults experiencing cancer (the INCAPAC study)<\/strong>. J Geriatr Oncol. 2019 Mar 20. pii: S1879-4068(18)30400-4. doi: 10.1016\/j.jgo.2019.03.006.\u00a0<\/p>\n<p>Gattoussi S, Cougnard-Gr\u00e9goire A, Korobelnik JF, Rougier MB, Delyfer MN, Schweitzer C, Le Goff M, Merle BMJ, Dartigues JF, Delcourt C. <strong>CHOROIDAL THICKNESS, VASCULAR FACTORS, AND AGE-RELATED MACULAR DEGENERATION: The ALIENOR Study<\/strong>. Retina. 2019 Jan;39(1):34-43<\/p>\n<p>Gattoussi S, Buitendijk GHS, Peto T, Leung I, Schmitz-Valckenberg S, Oishi A, Wolf S, De\u00e1k G, Delcourt C, Klaver CCW, Korobelnik JF; European Eye Epidemiology (E3) consortium. <strong>The European Eye Epidemiology spectral-domain optical coherence tomography classification of macular diseases for epidemiological studies<\/strong>. Acta Ophthalmol. 2019;97(4):364-371. Epub 2018 Sep 22.<\/p>\n<p>Giri A, Hellwege JN, Keaton JM, Park J, Qiu C, Warren HR, Torstenson ES, Kovesdy CP, Sun YV, Wilson OD, Robinson-Cohen C, Roumie CL, Chung CP, Birdwell KA, Damrauer SM, DuVall SL, Klarin D, Cho K, Wang Y, Evangelou E, Cabrera CP, Wain LV, Shrestha R, Mautz BS, Akwo EA, Sargurupremraj M, Debette S, Boehnke M, Scott LJ, Luan J, Zhao JH, Willems SM, Th\u00e9riault S, Shah N, Oldmeadow C, Almgren P, Li-Gao R, Verweij N, Boutin TS, Mangino M, Ntalla I, Feofanova E, Surendran P, Cook JP, Karthikeyan S, Lahrouchi N, Liu C, Sep\u00falveda N, Richardson TG, Kraja A, Amouyel P, Farrall M, Poulter NR; Understanding Society Scientific Group; International Consortium for Blood Pressure; Blood Pressure-International Consortium of Exome Chip Studies, Laakso M, Zeggini E, Sever P, Scott RA, Langenberg C, Wareham NJ, Conen D, Palmer CNA, Attia J, Chasman DI, Ridker PM, Melander O, Mook-Kanamori DO, Harst PV, Cucca F, Schlessinger D, Hayward C, Spector TD, Jarvelin MR, Hennig BJ, Timpson NJ, Wei WQ, Smith JC, Xu Y, Matheny ME, Siew EE, Lindgren C, Herzig KH, Dedoussis G, Denny JC, Psaty BM, Howson JMM, Munroe PB, Newton-Cheh C, Caulfield MJ, Elliott P, Gaziano JM, Concato J, Wilson PWF, Tsao PS, Velez Edwards DR, Susztak K; Million Veteran Program, O&rsquo;Donnell CJ, Hung AM, Edwards TL. <strong>Trans-ethnic association study of blood pressure determinants in over 750,000 individuals<\/strong>. Nat Genet. 2019;51(1):51-62. Epub 2018 Dec 21<\/p>\n<p>Grasset L, P\u00e9r\u00e8s K, Joly P, Sabath\u00e9 C, Foubert-Samier A, Dartigues JF, Helmer C. <strong>Secular trends of mortality and dementia-free life expectancy over a 10-year period in France<\/strong>. Eur J Epidemiol. 2019;34(2):115-123. 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Nat Genet. 2019;51(3):414-430. Epub 2019 Feb 28<\/p>\n<p>Larsson SC, Traylor M, Burgess S, Boncoraglio GB, Jern C, Micha\u00eblsson K, Markus HS; MEGASTROKE project of the International Stroke Genetics Consortium. <strong>Serum magnesium and calcium levels in relation to ischemic stroke: Mendelian randomization study<\/strong>. Neurology. 2019 26;92(9):e944-e950. Epub 2019 Jan 25<\/p>\n<p>Letellier N, Carri\u00e8re I, Gutierrez LA, Gabelle A, Dartigues JF, Dufouil C, Helmer C, Cadot E, Berr C. <strong>Influence of activity space on the association between neighborhood characteristics and dementia risk: results from the 3-City study cohort<\/strong>. BMC Geriatr. 2019;19(1):4. doi: 10.1186\/s12877-018-1017-7<\/p>\n<p>Lipnicki DM, Makkar SR, Crawford JD, Thalamuthu A, Kochan NA, Lima-Costa MF, Castro-Costa E, Ferri CP, Brayne C, Stephan B, Llibre-Rodriguez JJ, Llibre-Guerra JJ, Valhuerdi-Cepero AJ, Lipton RB, Katz MJ, Derby CA, Ritchie K, Ancelin ML, Carri\u00e8re I, Scarmeas N, Yannakoulia M, Hadjigeorgiou GM, Lam L, Chan WC, Fung A, Guaita A, Vaccaro R, Davin A, Kim KW, Han JW, Suh SW, Riedel-Heller SG, Roehr S, Pabst A, van Boxtel M, K\u00f6hler S, Deckers K, Ganguli M, Jacobsen EP, Hughes TF, Anstey KJ, Cherbuin N, Haan MN, Aiello AE, Dang K, Kumagai S, Chen T, Narazaki K, Ng TP, Gao Q, Nyunt MSZ, Scazufca M, Brodaty H, Numbers K, Trollor JN, Meguro K, Yamaguchi S, Ishii H, Lobo A, Lopez-Anton R, Santab\u00e1rbara J, Leung Y, Lo JW, Popovic G, Sachdev PS; for Cohort Studies of Memory in an International Consortium (COSMIC). <strong>Determinants of cognitive performance and decline in 20 diverse ethno-regional groups: A COSMIC collaboration cohort study<\/strong>. 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JAMA Neurol. 2019 Jun 10;76(9):1099-1108. doi: 10.1001\/jamaneurol.2019.1456<\/p>\n<p>Marklund M, Wu JHY, Imamura F, Del Gobbo LC, Fretts A, de Goede J, Shi P, Tintle N, Wennberg M, Aslibekyan S, Chen TA, de Oliveira Otto MC, Hirakawa Y, Eriksen HH, Kr\u00f6ger J, Laguzzi F, Lankinen M, Murphy RA, Prem K, Samieri C, Virtanen J, Wood AC, Wong K, Yang WS, Zhou X, Baylin A, Boer JMA, Brouwer IA, Campos H, Chaves PHM, Chien KL, de Faire U, Djouss\u00e9 L, Eiriksdottir G, El-Abbadi N, Forouhi NG, Michael Gaziano J, Geleijnse JM, Gigante B, Giles G, Guallar E, Gudnason V, Harris T, Harris WS, Helmer C, Hellenius ML, Hodge A, Hu FB, Jacques PF, Jansson JH, Kalsbeek A, Khaw KT, Koh WP, Laakso M, Leander K, Lin HJ, Lind L, Luben R, Luo J, McKnight B, Mursu J, Ninomiya T, Overvad K, Psaty BM, Rimm E, Schulze MB, Siscovick D, Skjelbo Nielsen M, Smith AV, Steffen BT, Steffen L, Sun Q, Sundstr\u00f6m J, Tsai MY, Tunstall-Pedoe H, Uusitupa MIJ, van Dam RM, Veenstra J, Monique Verschuren WM, Wareham N, Willett W, Woodward M, Yuan JM, Micha R, Lemaitre RN, Mozaffarian D, Ris\u00e9rus U; Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Fatty Acids and Outcomes Research Consortium (FORCE).<strong>Biomarkers of Dietary Omega-6 Fatty Acids and Incident Cardiovascular Disease and Mortality<\/strong>. Circulation. 2019;139(21):2422-2436.<\/p>\n<p>Merle BMJ, Colijn JM, Cougnard-Gr\u00e9goire A, de Koning-Backus APM, Delyfer MN, Kiefte-de Jong JC, Meester-Smoor M, F\u00e9art C, Verzijden T, Samieri C, Franco OH, Korobelnik JF, Klaver CCW, Delcourt C; EYE-RISK Consortium. <strong>Mediterranean Diet and Incidence of Advanced Age-Related Macular Degeneration: The EYE-RISK Consortium<\/strong>. Ophthalmology. 2019;126(3):381-390. Epub 2018 Aug 13.<\/p>\n<p>Mishra A, Chauhan G, Violleau MH, Vojinovic D, Jian X, Bis JC, Li S, Saba Y, Grenier-Boley B, Yang Q, Bartz TM, Hofer E, Soumar\u00e9 A, Peng F, Duperron MG, Foglio M, Mosley TH, Schmidt R, Psaty BM, Launer LJ, Boerwinkle E, Zhu Y, Mazoyer B, Lathrop M, Bellenguez C, Van Duijn CM, Ikram MA, Schmidt H, Longstreth WT, Fornage M, Seshadri S, Joutel A, Tzourio C, Debette S. <strong>Association of variants in HTRA1 and NOTCH3 with MRI-defined extremes of cerebral small vessel disease in older subjects<\/strong>. Brain. 2019;142(4):1009-1023.<\/p>\n<p>Na\u00ebl V, P\u00e9r\u00e8s K, Dartigues JF, Letenneur L, Amieva H, Arleo A, Scherlen AC, Tzourio C, Berr C, Carri\u00e8re I, Delcourt C, Helmer C; Sense-Cog consortium. <strong>Vision loss and 12-year risk of dementia in older adults: the 3C cohort study<\/strong>. Eur J Epidemiol. 2019;34(2):141-152. Epub 2019 Jan 4.<\/p>\n<p>Na\u00ebl V, Moreau G, Monferm\u00e9 S, Cougnard-Gr\u00e9goire A, Scherlen AC, Arleo A, Korobelnik JF, Delcourt C, Helmer C. <strong>Prevalence and Associated Factors of Uncorrected Refractive Error in Older Adults in a Population-Based Study in France<\/strong>. JAMA Ophthalmol. 2019;137(1):3-11<\/p>\n<p>NCD Risk Factor Collaboration (NCD-RisC). <strong>Rising rural body-mass index is the main driver of the global obesity epidemic in adults<\/strong>. Nature. 2019; 569(7755):260-264. 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J Frailty Aging. 2019;8(1):42-47.<\/p>\n<p>P\u00e9quignot R, Dufouil C, P\u00e9r\u00e8s K, Artero S, Tzourio C, Empana JP. <strong>Depression Increases the Risk of Death Independently From Vascular Events in Elderly Individuals: The Three-City Study<\/strong>. J Am Geriatr Soc. 2019;67(3):546-552. Epub 2019 Jan 17.<\/p>\n<p>Pilleron S, Weber D, P\u00e9r\u00e8s K, Colpo M, Gomez-Cabrero D, Stuetz W, Dartigues JF, Ferrucci L, Bandinelli S, Garcia-Garcia FJ, Grune T, F\u00e9art C; FRAILOMIC initiative. <strong>Patterns of circulating fat-soluble vitamins and carotenoids and risk of frailty in four European cohorts of older adults<\/strong>. Eur J Nutr. 2019; 58(1):379-389. Epub 2018 Jan 27<\/p>\n<p>Planche V, Coup\u00e9 P, Helmer C, Le Goff M, Amieva H, Tison F, Dartigues JF, Catheline G. <strong>Evolution of brain atrophy subtypes during aging predicts long-term cognitive decline and future Alzheimer&rsquo;s clinical syndrome<\/strong>. Neurobiol Aging. 2019;79:22-29. 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Nat Genet. 2019 Nov;51(11):1624-1636. Epub 2019 Oct 21<\/p>\n<p>Silenou BC, Avalos M, Helmer C, Berr C, Pariente A, Jacqmin-Gadda H. <strong>Health administrative data enrichment using cohort information: Comparative evaluation of methods by simulation and application to real data<\/strong>. PLoS One. 2019;14(1):e0211118. eCollection 2019<\/p>\n<p>Tully PJ, Helmer C, Peters R, Tzourio C. Exploiting Drug-Apolipoprotein E <strong>Gene Interactions in Hypertension to Preserve Cognitive Function: The 3-City Cohort Study<\/strong>. J Am Med Dir Assoc. 2019 Feb;20(2):188-194.e4. doi: 10.1016\/j.jamda.2018.08.002. 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Commun Biol. 2019;2:285. doi: 10.1038\/s42003-019-0537-9. eCollection 2019<\/p>\n<p>Walter S, Dufouil C, Gross AL, Jones RN, Mungas D, Filshtein TJ, Manly JJ, Arpawong TE, Glymour MM. <strong>Neuropsychological Test Performance and MRI Markers of Dementia Risk: Reducing Education Bias<\/strong>. Alzheimer Dis Assoc Disord. 2019;33(3):179-185<\/p>\n<p>Wrigglesworth J, Ancelin ML, Ritchie K, Ryan J. <strong>Association between DNA methylation of the KITLG gene and cortisol levels under stress: a replication study<\/strong>. Stress. 2019;22(1):162-168. Epub 2018 Oct 9<\/p>\n<p>Yang J, Tr\u00e9po E, Nahon P, Cao Q, Moreno C, Letouz\u00e9 E, Imbeaud S, Gustot T, Deviere J, Debette S, Amouyel P, Bioulac-Sage P, Calderaro J, Ganne-Carri\u00e9 N, Laurent A, Blanc JF, Guyot E, Sutton A, Ziol M, Zucman-Rossi J, Nault JC. <strong>PNPLA3 and TM6SF2 variants as risk factors of hepatocellular carcinoma across various etiologies and severity of underlying liver diseases<\/strong>. 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Epub 2018 Nov 9<\/p>\n<\/div><\/div><\/div><\/div><\/div><style type=\"text\/css\">.fusion-accordian  #accordion-880-19 .panel-title a .fa-fusion-box{ color: #ffffff;}.fusion-accordian  #accordion-880-19 .panel-title a .fa-fusion-box:before{ font-size: 16px; width: 16px;}.fusion-accordian  #accordion-880-19 .panel-title a{font-size:24px;}.fusion-accordian  #accordion-880-19 .fa-fusion-box { background-color: #212934;border-color: #212934;}.fusion-accordian  #accordion-880-19 .panel-title a:hover, #accordion-880-19 .fusion-toggle-boxed-mode:hover .panel-title a { color: #65bc7b;}.fusion-accordian  #accordion-880-19 .panel-title .active .fa-fusion-box,.fusion-accordian  #accordion-880-19 .panel-title a:hover .fa-fusion-box { background-color: #65bc7b!important;border-color: #65bc7b!important;}<\/style><div class=\"accordian fusion-accordian\"><div class=\"panel-group\" id=\"accordion-880-19\"><div class=\"fusion-panel panel-default\"><div class=\"panel-heading\"><h4 class=\"panel-title toggle\"><a aria-expanded=\"false\" aria-controls=\"1f9c0e93b458f319d\" role=\"button\" data-toggle=\"collapse\" data-parent=\"#accordion-880-19\" data-target=\"#1f9c0e93b458f319d\" href=\"#1f9c0e93b458f319d\"><span class=\"fusion-toggle-icon-wrapper\" aria-hidden=\"true\"><i class=\"fa-fusion-box\" aria-hidden=\"true\"><\/i><\/span><span class=\"fusion-toggle-heading\">2020<\/span><\/a><\/h4><\/div><div id=\"1f9c0e93b458f319d\" class=\"panel-collapse collapse \"><div class=\"panel-body toggle-content fusion-clearfix\">\n<p style=\"text-align: justify;\">Acar \u0130E, Lores-Motta L, Colijn JM, Meester-Smoor MA, Verzijden T, Cougnard-Gregoire A, Ajana S, Merle BMJ, de Breuk A, Heesterbeek TJ, van den Akker E, Daha MR, Claes B, Pauleikhoff D, Hense HW, van Duijn CM, Fauser S, Hoyng CB, Delcourt C, Klaver CCW, Galesloot TE, den Hollander AI; EYE-RISK Consortium. Integrating Metabolomics, Genomics, and Disease Pathways in Age-Related Macular Degeneration: The EYE-RISK Consortium. Ophthalmology. 2020;127(12):1693-1709. Epub 2020 Jun 14<\/p>\n<p style=\"text-align: justify;\">Ancelin ML, Carriere I, Artero S, Maller JJ, Meslin C, Dupuy AM, Ritchie K, Ryan J, Chaudieu I. <strong>Structural brain changes with lifetime trauma and re-experiencing symptoms is 5-HTTLPR genotype-dependent<\/strong>. Eur J Psychotraumatol. 2020 Mar 4;11(1):1733247. doi: 10.1080\/20008198.2020.1733247. eCollection 2020<\/p>\n<p style=\"text-align: justify;\">Ancelin ML, Norton J, Canonico M, Scarabin PY, Ritchie K, Ryan J. <strong>Aromatase (CYP19A1) gene variants, sex steroid levels, and late-life depression. Depress Anxiety<\/strong>. 2020;37(2):146-155. doi: 10.1002\/da.22974. 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Stroke. 2020;51(7):2111-2121. doi: 10.1161\/STROKEAHA.119.027544. Epub 2020 Jun 10<\/p>\n<p style=\"text-align: justify;\">Arnould L, De Lazzer A, Seydou A, Binquet C, Bron AM, Creuzot-Garcher C. <strong>Diagnostic ability of spectral-domain optical coherence tomography peripapillary retinal nerve fiber layer thickness to discriminate glaucoma patients from controls in an elderly population (The MONTRACHET study)<\/strong>. Acta Ophthalmol. 2020 Dec;98(8):e1009-e1016. doi: 10.1111\/aos.14448. Epub 2020 Apr 24.<\/p>\n<p style=\"text-align: justify;\">Arnould L, Guillemin M, Seydou A, Gabrielle PH, Bourredjem A, Kawasaki R, Binquet C, Bron AM, Creuzot-Garcher C. <strong>Association between the retinal vascular network and retinal nerve fiber layer in the elderly: The Montrachet study<\/strong>. PLoS One. 2020;15(10):e0241055. eCollection 2020.<\/p>\n<p style=\"text-align: justify;\">Bae JB, Lipnicki DM, Han JW, Sachdev PS, Kim TH, Kwak KP, Kim BJ, Kim SG, Kim JL, Moon SW, Park JH, Ryu SH, Youn JC, Lee DY, Lee DW, Lee SB, Lee JJ, Jhoo JH, Llibre-Rodriguez JJ, Llibre-Guerra JJ, Valhuerdi-Cepero AJ, Ritchie K, Ancelin ML, Carriere I, Skoog I, Najar J, Sterner TR, Scarmeas N, Yannakoulia M, Dardiotis E, Meguro K, Kasai M, Nakamura K, Riedel-Heller S, Roehr S, Pabst A, van Boxtel M, K\u00f6hler S, Ding D, Zhao Q, Liang X, Scazufca M, Lobo A, De-la-C\u00e1mara C, Lobo E, Kim KW; for Cohort Studies of Memory in an International Consortium (COSMIC). <strong>Does parity matter in women&rsquo;s risk of dementia? A COSMIC collaboration cohort study<\/strong>. BMC Med. 2020 Aug 5;18(1):210. doi: 10.1186\/s12916-020-01671-1<\/p>\n<p style=\"text-align: justify;\">Biarn\u00e9s M, Colijn JM, Sousa J, Ferraro LL, Garcia M, Verzijden T, Meester-Smoor MA, Delcourt C, Klaver CCW, den Hollander AI, Lengyel I, Peto T, Mon\u00e9s J; EYE-RISK Consortium. <strong>Genotype- and Phenotype-Based Subgroups in Geographic Atrophy Secondary to Age-Related Macular Degeneration: The EYE-RISK Consortium<\/strong>. Ophthalmol Retina. 2020 Dec;4(12):1129-1137. doi: 10.1016\/j.oret.2020.04.014. Epub 2020 May 1<\/p>\n<p style=\"text-align: justify;\">Canonico M, Artaud F, Tzourio C, Elbaz A. <strong>Association of Reproductive History With Motor Function and Disability in Aging Women<\/strong>. J Am Geriatr Soc. 2020;68(3):585-594. Epub 2019 Nov 25<\/p>\n<p style=\"text-align: justify;\">Carles S, Carri\u00e8re I, Reppermund S, Davin A, Guaita A, Vaccaro R, Ganguli M, Jacobsen EP, Beer JC, Riedel-Heller SG, Roehr S, Pabst A, Haan MN, Brodaty H, Kochan NA, Trollor JN, Kim KW, Han JW, Suh SW, Lobo A, la Camara C, Lobo E, Lipnicki DM, Sachdev PS, Ancelin ML, Ritchie K; for Cohort Studies of Memory in an International Consortium (COSMIC). <strong>A cross-national study of depression in preclinical dementia: A COSMIC collaboration study<\/strong>. Alzheimers Dement. 2020;16(11):1544-1552. Epub 2020 Sep 3<\/p>\n<p style=\"text-align: justify;\">Cremer A, Boutouyrie P, Laurent S, Gosse P, Tzourio C. <strong>Orthostatic hypotension: a marker of blood pressure variability and arterial stiffness: a cross-sectional study on an elderly population: the 3-City study<\/strong>. J Hypertens. 2020 Jun;38(6):1103-1109. doi: 10.1097\/HJH.0000000000002374<\/p>\n<p style=\"text-align: justify;\">Delyfer MN, Legout P, Le Goff M, Blaizeau M, Rougier MB, Schweitzer C, Korobelnik JF, Delcourt C. <strong>Prevalence of epiretinal membranes in the ageing population using retinal colour images and SD-OCT: the Alienor Study<\/strong>. Acta Ophthalmol. 2020 Apr 17. doi: 10.1111\/aos.14422. [Epub ahead of print]\n<p style=\"text-align: justify;\">Ding J, Davis-Plourde KL, Sedaghat S, Tully PJ, Wang W, Phillips C, Pase MP, Himali JJ, Gwen Windham B, Griswold M, Gottesman R, Mosley TH, White L, Gu\u00f0nason V, Debette S, Beiser AS, Seshadri S, Ikram MA, Meirelles O, Tzourio C, Launer LJ. <strong>Antihypertensive medications and risk for incident dementia and Alzheimer&rsquo;s disease: a meta-analysis of individual participant data from prospective cohort studies<\/strong>. Lancet Neurol. 2020 Jan;19(1):61-70. Epub 2019 Nov 6<\/p>\n<p style=\"text-align: justify;\">Dupr\u00e9 C, Bongue B, Helmer C, Dartigues JF, Hupin D, Roche F, Berr C, Carri\u00e8re I. <strong>Physical activity types and risk of dementia in community-dwelling older people: the Three-City cohor<\/strong>t. BMC Geriatr. 2020;20(1):132.<\/p>\n<p style=\"text-align: justify;\">Dutheil C, Le Goff M, Cougnard-Gr\u00e9goire A, Gattoussi S, Korobelnik JF, Rougier MB, Schweitzer C, Delcourt C, Delyfer MN. <strong>Incidence and Risk Factors of Reticular Pseudodrusen Using Multimodal Imaging<\/strong>. JAMA Ophthalmol. 2020 May 1;138(5):467-477. doi: 10.1001\/jamaophthalmol.2020.0266<\/p>\n<p style=\"text-align: justify;\">Edde M, Theaud G, Rheault F, Dilharreguy B, Helmer C, Dartigues JF, Amieva H, Allard M, Descoteaux M, Catheline G. <strong>Free water: A marker of age-related modifications of the cingulum white matter and its association with cognitive decline<\/strong>. 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Neurology. 2020 May 12;94(19):e2014-e2025.doi: 10.1212\/WNL.0000000000009399<\/p>\n<p style=\"text-align: justify;\">Sargurupremraj M, Suzuki H, Jian X, Sarnowski C, Evans TE, Bis JC, Eiriksdottir G, Sakaue S, Terzikhan N, Habes M, Zhao W, Armstrong NJ, Hofer E, Yanek LR, Hagenaars SP, Kumar RB, van den Akker EB, McWhirter RE, Trompet S, Mishra A, Saba Y, Satizabal CL, Beaudet G, Petit L, Tsuchida A, Zago L, Schilling S, Sigurdsson S, Gottesman RF, Lewis CE, Aggarwal NT, Lopez OL, Smith JA, Vald\u00e9s Hern\u00e1ndez MC, van der Grond J, Wright MJ, Knol MJ, D\u00f6rr M, Thomson RJ, Bordes C, Le Grand Q, Duperron MG, Smith AV, Knopman DS, Schreiner PJ, Evans DA, Rotter JI, Beiser AS, Maniega SM, Beekman M, Trollor J, Stott DJ, Vernooij MW, Wittfeld K, Niessen WJ, Soumar\u00e9 A, Boerwinkle E, Sidney S, Turner ST, Davies G, Thalamuthu A, V\u00f6lker U, van Buchem MA, Bryan RN, Dupuis J, Bastin ME, Ames D, Teumer A, Amouyel P, Kwok JB, B\u00fclow R, Deary IJ, Schofield PR, Brodaty H, Jiang J, Tabara Y, Setoh K, Miyamoto S, Yoshida K, Nagata M, Kamatani Y, Matsuda F, Psaty BM, Bennett DA, De Jager PL, Mosley TH, Sachdev PS, Schmidt R, Warren HR, Evangelou E, Tr\u00e9gou\u00ebt DA; International Network against Thrombosis (INVENT) Consortium; International Headache Genomics Consortium (IHGC), Ikram MA, Wen W, DeCarli C, Srikanth VK, Jukema JW, Slagboom EP, Kardia SLR, Okada Y, Mazoyer B, Wardlaw JM, Nyquist PA, Mather KA, Grabe HJ, Schmidt H, Van Duijn CM, Gudnason V, Longstreth WT Jr, Launer LJ, Lathrop M, Seshadri S, Tzourio C, Adams HH, Matthews PM, Fornage M, Debette S. <strong>Cerebral small vessel disease genomics and its implications across the lifespan<\/strong>. Nat Commun. 2020;11(1):6285<\/p>\n<p style=\"text-align: justify;\">Schijven D, Stevelink R, McCormack M, van Rheenen W, Luykx JJ, Koeleman BPC, Veldink JH; Project MinE ALS GWAS Consortium; International League Against Epilepsy Consortium on Complex Epilepsies. <strong>Analysis of shared common genetic risk between amyotrophic lateral sclerosis and epilepsy<\/strong>. Neurobiol Aging. 2020 Aug;92:153.e1-153.e5. doi: 10.1016\/j.neurobiolaging.2020.04.011. Epub 2020 Apr 18<\/p>\n<p style=\"text-align: justify;\">Sherva R, Gross A, Mukherjee S, Koesterer R, Amouyel P, Bellenguez C, Dufouil C, Bennett DA, Chibnik L, Cruchaga C, Del-Aguila J, Farrer LA, Mayeux R, Munsie L, Winslow A, Newhouse S, Saykin AJ, Kauwe JSK; <strong>Alzheimer&rsquo;s Disease Genetics Consortium, Crane PK, Green RC. Genome-wide association study of rate of cognitive decline in Alzheimer&rsquo;s disease patients identifies novel genes and pathways<\/strong>. Alzheimers Dement. 2020;16(8):1134-1145. doi: 10.1002\/alz.12106. Epub 2020 Jun 23<\/p>\n<p style=\"text-align: justify;\">Shin J, Ma S, Hofer E, Patel Y, Vosberg DE, Tilley S, Roshchupkin GV, Sousa AMM, Jian X, Gottesman R, Mosley TH, Fornage M, Saba Y, Pirpamer L, Schmidt R, Schmidt H, Carrion-Castillo A, Crivello F, Mazoyer B, Bis JC, Li S, Yang Q, Luciano M, Karama S, Lewis L, Bastin ME, Harris MA, Wardlaw JM, Deary IE, Scholz M, Loeffler M, Witte AV, Beyer F, Villringer A, Armstrong NJ, Mather KA, Ames D, Jiang J, Kwok JB, Schofield PR, Thalamuthu A, Trollor JN, Wright MJ, Brodaty H, Wen W, Sachdev PS, Terzikhan N, Evans TE, Adams HHHH, Ikram MA, Frenzel S, Auwera-Palitschka SV, Wittfeld K, B\u00fclow R, Grabe HJ, Tzourio C, Mishra A, Maingault S, Debette S, Gillespie NA, Franz CE, Kremen WS, Ding L, Jahanshad N; ENIGMA Consortium, Sestan N, Pausova Z, Seshadri S, Paus T; neuroCHARGE Working Group. <strong>Global and Regional Development of the Human Cerebral Cortex: Molecular Architecture and Occupational Aptitudes<\/strong>. Cereb Cortex. 2020 Jun 1;30(7):4121-4139. doi: 10.1093\/cercor\/bhaa035<\/p>\n<p style=\"text-align: justify;\">Tully PJ, Alp\u00e9rovitch A, Soumar\u00e9 A, Mazoyer B, Debette S, Tzourio C. <strong>Association Between Cerebral Small Vessel Disease With Antidepressant Use and Depression: 3C Dijon Magnetic Resonance Imaging Study<\/strong>. Stroke. 2020;51(2):402-408. Epub 2019 Dec 12<\/p>\n<p style=\"text-align: justify;\">Thomas A, Baillet M, Proust-Lima C, F\u00e9art C, Foubert-Samier A, Helmer C, Catheline G, Samieri C. <strong>Blood polyunsaturated omega-3 fatty acids, brain atrophy, cognitive decline, and dementia risk.<\/strong> Alzheimers Dement. 2020 Oct 8. doi: 10.1002\/alz.12195. <\/p>\n<p style=\"text-align: justify;\">Tully PJ, Kurth T, Elbaz A, Tzourio C. <strong>Convergence of psychiatric symptoms and restless legs syndrome: A cross-sectional study in an elderly French population<\/strong>. J Psychosom Res. 2020;128:109884. Epub 2019 Nov 25<\/p>\n<p style=\"text-align: justify;\">Phillip J. Tully, Yuichiro Yano, Lenore J. Launer, Kazuomi Kario, Michiaki Nagai, Simon P. Mooijaart, Jurgen A. H. R. Claassen, Simona Lattanzi, Andrew D. Vincent, Christophe Tzourio, the Variability in Blood Pressure and Brain Health Consortium. <strong>Association Between Blood Pressure Variability and Cerebral Small\u2010Vessel Disease: A Systematic Review and Meta\u2010Analysis<\/strong>. J Am Heart Assoc. 2020; 9(1): e013841. Published online 2019 Dec 24<\/p>\n<p style=\"text-align: justify;\">Wolters FJ, Chibnik LB, Waziry R, Anderson R, Berr C, Beiser A, Bis JC, Blacker D, Bos D, Brayne C, Dartigues JF, Darweesh SKL, Davis-Plourde KL, de Wolf F, Debette S, Dufouil C, Fornage M, Goudsmit J, Grasset L, Gudnason V, Hadjichrysanthou C, Helmer C, Ikram MA, Ikram MK, Joas E, Kern S, Kuller LH, Launer L, Lopez OL, Matthews FE, McRae-McKee K, Meirelles O, Mosley TH Jr, Pase MP, Psaty BM, Satizabal CL, Seshadri S, Skoog I, Stephan BCM, Wetterberg H, Wong MM, Zettergren A, Hofman A. <strong>Twenty-seven-year time trends in dementia incidence in Europe and the United States: The Alzheimer Cohorts Consortium<\/strong>. Neurology. 2020;95(5):e519-e531. Epub 2020 Jul 1<\/p>\n<p style=\"text-align: justify;\">Zamudio-Rodr\u00edguez A, Letenneur L, F\u00e9art C, Avila-Funes JA, Amieva H, P\u00e9r\u00e8s K. <strong>The disability process: is there a place for frailty?<\/strong> Age Ageing. 2020;49(5):764-770<\/p>\n<\/div><\/div><\/div><\/div><\/div><style type=\"text\/css\">.fusion-accordian  #accordion-880-20 .panel-title a .fa-fusion-box{ color: #ffffff;}.fusion-accordian  #accordion-880-20 .panel-title a .fa-fusion-box:before{ font-size: 16px; width: 16px;}.fusion-accordian  #accordion-880-20 .panel-title a{font-size:24px;}.fusion-accordian  #accordion-880-20 .fa-fusion-box { background-color: #212934;border-color: #212934;}.fusion-accordian  #accordion-880-20 .panel-title a:hover, #accordion-880-20 .fusion-toggle-boxed-mode:hover .panel-title a { color: #65bc7b;}.fusion-accordian  #accordion-880-20 .panel-title .active .fa-fusion-box,.fusion-accordian  #accordion-880-20 .panel-title a:hover .fa-fusion-box { background-color: #65bc7b!important;border-color: #65bc7b!important;}<\/style><div class=\"accordian fusion-accordian\"><div class=\"panel-group\" id=\"accordion-880-20\"><div class=\"fusion-panel panel-default\"><div class=\"panel-heading\"><h4 class=\"panel-title toggle\"><a aria-expanded=\"false\" aria-controls=\"adc049552a50a74bc\" role=\"button\" data-toggle=\"collapse\" data-parent=\"#accordion-880-20\" data-target=\"#adc049552a50a74bc\" href=\"#adc049552a50a74bc\"><span class=\"fusion-toggle-icon-wrapper\" aria-hidden=\"true\"><i class=\"fa-fusion-box\" aria-hidden=\"true\"><\/i><\/span><span class=\"fusion-toggle-heading\">2021<\/span><\/a><\/h4><\/div><div id=\"adc049552a50a74bc\" class=\"panel-collapse collapse \"><div class=\"panel-body toggle-content fusion-clearfix\">\n<p style=\"text-align: justify;\">Ajana S, Cougnard-Gr\u00e9goire A, Colijn JM, Merle BM, Verzijden T, de Jong PT, Hofman A, Vingerling JR, Hejblum BP, Korobelnik JF, Meester-Smoor MA, Ueffing M, Jacqmin-Gadda H, Klaver CC, Delcourt C; EYE-RISK Consortium. <strong>Predicting Progression to Advanced Age-Related Macular Degeneration from Clinical, Genetic, and Lifestyle Factors Using Machine Learning<\/strong>. Ophthalmology. 2021;128(4):587-597. Epub 2020 Sep 2<\/p>\n<p style=\"text-align: justify;\">Ancelin ML, Carri\u00e8re I, Artero S, Maller JJ, Meslin C, Dupuy AM, Ritchie K, Ryan J, Chaudieu I. <strong>Structural brain alterations in older adults exposed to early-life adversity<\/strong>. Psychoneuroendocrinology. 2021;129:105272. Epub 2021 May 15<\/p>\n<p style=\"text-align: justify;\">Ancelin ML, Norton J, Ritchie K, Chaudieu I, Ryan J. <strong>Steroid 21-hydroxylase gene variants and late-life depression<\/strong>. BMC Res Notes. 2021;14(1):203<\/p>\n<p style=\"text-align: justify;\">Ancelin ML, Norton J, Ritchie K, Chaudieu I, Ryan J. <strong>11\u03b2-Hydroxylase (CYP11B1) gene variants and new-onset depression in later life<\/strong>. J Psychiatry Neurosci. 2021;46(1):E147-E153.<\/p>\n<p style=\"text-align: justify;\">Ancelin ML, Norton J, Scali J, Ritchie K, Chaudieu I, Ryan J. <strong>A Prospective Study of Diurnal Cortisol and Incident Dementia in Community-Dwelling Older Adults<\/strong>. J Alzheimers Dis. 2021;82(3):899-904<\/p>\n<p style=\"text-align: justify;\">Andr\u00e9 P, Pais de Barros JP, Mj Merle B, Samieri C, Helmer C, Delcourt C, F\u00e9art C. <strong>Mediterranean diet and prudent diet are both associated with low circulating esterified 3-hydroxy fatty acids, a proxy of LPS burden, among older adults<\/strong>. Am J Clin Nutr. 2021 May 24:nqab126. doi: 10.1093\/ajcn\/nqab126.<\/p>\n<p style=\"text-align: justify;\">Arnould L, Guenancia C, Binquet C, Delcourt C, Chiquet C, Daien V, Cottin Y, Bron AM, Acar N, Creuzot-Garcher C. <strong>Retinal vascular network: Changes with aging and systemic vascular disease (cardiac and cerebral)<\/strong>. <em>J<\/em> Fr Ophtalmol. 2021 Nov 23:S0181-5512(21)00521-0. doi: 10.1016\/j.jfo.2021.09.004.<\/p>\n<p style=\"text-align: justify;\">Baksh RA, Ritchie CW, Terrera GM, Norton J, Raymont V, Ritchie K. <strong>The association between anxiety disorders and hippocampal volume in older adults<\/strong>. Psychol Aging. 2021;36(2):288-297. doi: 10.1037\/pag0000597. Epub 2021 Mar 4.<\/p>\n<p style=\"text-align: justify;\">Bastard P, Gervais A, Le Voyer T, Rosain J, Philippot Q, Manry J, Michailidis E, Hoffmann HH, Eto S, Garcia-Prat M, Bizien L, Parra-Mart\u00ednez A, Yang R, Haljasm\u00e4gi L, Migaud M, S\u00e4rekannu K, Maslovskaja J, de Prost N, Tandjaoui-Lambiotte Y, Luyt CE, Amador-Borrero B, Gaudet A, Poissy J, Morel P, Richard P, Cognasse F, Troya J, Trouillet-Assant S, Belot A, Saker K, Gar\u00e7on P, Rivi\u00e8re JG, Lagier JC, Gentile S, Rosen LB, Shaw E, Morio T, Tanaka J, Dalmau D, Tharaux PL, Sene D, Stepanian A, Megarbane B, Triantafyllia V, Fekkar A, Heath JR, Franco JL, Anaya JM, Sol\u00e9-Viol\u00e1n J, Imberti L, Biondi A, Bonfanti P, Castagnoli R, Delmonte OM, Zhang Y, Snow AL, Holland SM, Biggs C, Moncada-V\u00e9lez M, Arias AA, Lorenzo L, Boucherit S, Coulibaly B, Anglicheau D, Planas AM, Haerynck F, Duvlis S, Nussbaum RL, Ozcelik T, Keles S, Bousfiha AA, El Bakkouri J, Ramirez-Santana C, Paul S, Pan-Hammarstr\u00f6m Q, Hammarstr\u00f6m L, Dupont A, Kurolap A, Metz CN, Aiuti A, Casari G, Lampasona V, Ciceri F, Barreiros LA, Dominguez-Garrido E, Vidigal M, Zatz M, van de Beek D, Sahanic S, Tancevski I, Stepanovskyy Y, Boyarchuk O, Nukui Y, Tsumura M, Vidaur L, Tangye SG, Burrel S, Duffy D, Quintana-Murci L, Klocperk A, Kann NY, Shcherbina A, Lau YL, Leung D, Coulongeat M, Marlet J, Koning R, Reyes LF, Chauvineau-Grenier A, Venet F, Monneret G, Nussenzweig MC, Arrestier R, Boudhabhay I, Baris-Feldman H, Hagin D, Wauters J, Meyts I, Dyer AH, Kennelly SP, Bourke NM, Halwani R, Sharif-Askari NS, Dorgham K, Sallette J, Sedkaoui SM, AlKhater S, Rigo-Bonnin R, Morandeira F, Roussel L, Vinh DC, Ostrowski SR, Condino-Neto A, Prando C, Bonradenko A, Spaan AN, Gilardin L, Fellay J, Lyonnet S, Bilguvar K, Lifton RP, Mane S; HGID Lab; COVID Clinicians; COVID-STORM Clinicians; NIAID Immune Response to COVID Group; NH-COVAIR Study Group; Danish CHGE; Danish Blood Donor Study; St. James&rsquo;s Hospital; SARS CoV2 Interest group; French COVID Cohort Study Group; Imagine COVID-Group; Milieu Int\u00e9rieur Consortium; CoV-Contact Cohort; Amsterdam UMC Covid-19; Biobank Investigators; COVID Human Genetic Effort; CONSTANCES cohort; 3C-Dijon Study; Cerba Health-Care; Etablissement du Sang study group, Anderson MS, Boisson B, B\u00e9ziat V, Zhang SY, Vandreakos E, Hermine O, Pujol A, Peterson P, Mogensen TH, Rowen L, Mond J, Debette S, de Lamballerie X, Duval X, Mentr\u00e9 F, Zins M, Soler-Palacin P, Colobran R, Gorochov G, Solanich X, Susen S, Martinez-Picado J, Raoult D, Vasse M, Gregersen PK, Piemonti L, Rodr\u00edguez-Gallego C, Notarangelo LD, Su HC, Kisand K, Okada S, Puel A, Jouanguy E, Rice CM, Tiberghien P, Zhang Q, Cobat A, Abel L, Casanova JL. <strong>Autoantibodies neutralizing type I IFNs are present in ~4% of uninfected individuals over 70 years old and account for ~20% of COVID-19 deaths.<\/strong> Sci Immunol. 2021;6(62):eabl4340.<\/p>\n<p style=\"text-align: justify;\">Ben Ghezala I, Seydou A, Gabrielle PH, Bouche-Pillon J, Binquet C, Delcourt C, Daien V, Bron AM, Creuzot-Garcher C. <strong>Epidemiology of vitreomacular interface abnormalities usign macular spectral-domain optical coherence tomography in an elderly population (THE MONTRACHET STUDY)<\/strong>. Retina. 2021;41(1):60-67. doi: 10.1097\/IAE.0000000000002802<\/p>\n<p style=\"text-align: justify;\">Ben-Hassen C, Helmer C, Berr C, Jacqmin-Gadda H. <strong>5-Year dynamic prediction of dementia using repeated measures of cognitive tests and a dependency scale<\/strong>. Am J Epidemiol. 2021 Nov 9:kwab269. doi: 10.1093\/aje\/kwab269.<\/p>\n<p style=\"text-align: justify;\">Ben Ghezala I, Seydou A, Gabrielle PH, Bouche-Pillon J, Binquet C, Delcourt C, Daien V, Bron AM, Creuzot-Garcher C. <strong>Epidemiology of vitreomacular interface abnormalties using macular spectral-domain optical coherence tomography in an elderly population (THE MONTRACHET STUDY).<\/strong> Retina. 2021;41(1):60-67. doi: 10.1097\/IAE.0000000000002802<\/p>\n<p style=\"text-align: justify;\">Caillot-Ranjeva S, Amieva H, Meillon C, Helmer C, Berr C, Bergua V. <strong>Similarities in cognitive abilities in older couples: a study of mutual influences<\/strong>. J Clin Exp Neuropsychol. 2021 Feb;43(1):78-90. doi: 10.1080\/13803395.2021.1874882. Epub 2021 Feb 8<\/p>\n<p style=\"text-align: justify;\">Caillot-Ranjeva S, Gourlain S, Amieva H, Helmer C, Bergua V. <strong>Study of mutual influence between trait anxiety and risk of depression among older couples facing cancer.<\/strong> J Geriatr Oncol. 2021;12(4):605-611. Epub 2020 Sep 29<\/p>\n<p style=\"text-align: justify;\">Carles S, Tadd\u00e9 BO, Berr C, Helmer C, Jacqmin-Gadda H, Carri\u00e8re I, Proust-Lima C. <strong>Dynamic reciprocal relationships between cognitive and functional declines along the Alzheimer&rsquo;s disease continuum in the prospective COGICARE study<\/strong>. Alzheimers Res Ther. 2021;13(1):148. doi: 10.1186\/s13195-021-00887-4.<\/p>\n<p style=\"text-align: justify;\">Chambon C, Neyraud E, Sayd T, Bros P, Di Biagio R, Hyvrier F, F\u00e9art C, Andr\u00e9 P, Rodriguez-Artalejo F, Lopez-Garcia E, Garcia-Esquinas E, Gomez-Cabrero D, Proctor G, Morzel M.<strong> The salivary proteome reflects some traits of dietary habits in diabetic and non-diabetic older adults.<\/strong> Eur J Nutr. 2021;60(8):4331-4344. Epub 2021 May 26<\/p>\n<p style=\"text-align: justify;\">Chemaly A, Arnould L, Seydou A, Gabrielle PH, Baudin F, Acar N, Creuzot-Garcher C. <strong>Plasma fatty acids and primary open-angle glaucoma in the elderly: the Montrachet population-based study<\/strong>. BMC Ophthalmol. 2021 Mar 23;21(1):146. doi: 10.1186\/s12886-021-01910-w.<\/p>\n<p style=\"text-align: justify;\">Colijn JM, Meester-Smoor M, Verzijden T, de Breuk A, Silva R, Merle BMJ, Cougnard-Gr\u00e9goire A, Hoyng CB, Fauser S, Coolen A, Creuzot-Garcher C, Hense HW, Ueffing M, Delcourt C, den Hollander AI, Klaver CCW; EYE-RISK Consortium. <strong>Genetic Risk, Lifestyle, and Age-Related Macular Degeneration in Europe: The EYE-RISK Consortium<\/strong>. Ophthalmology. 2021;128(7):1039-1049. Epub 2020 Nov 28<\/p>\n<p style=\"text-align: justify;\">Cosh S, Carriere I, Delcourt C, Helmer C, Consortium TS. <strong>A dimensional approach to understanding the relationship between self-reported hearing loss and depression over 12 years: the Three-City study<\/strong>. Aging Ment Health. 2021;25(5):954-961. Epub 2020 Mar 13<\/p>\n<p style=\"text-align: justify;\">Chuy V, Gentreau M, Artero S, Berticat C, Rigalleau V, P\u00e9r\u00e8s K, Helmer C, Samieri C, F\u00e9art C. <strong>Simple carbohydrate intake and higher risk for physical frailty over 15 years in community-dwelling older adults<\/strong>. J Gerontol A Biol Sci Med Sci. 2021 Aug 21:glab243.<\/p>\n<p style=\"text-align: justify;\">Cyprien F, Berr C, Maller JJ, Meslin C, Gentreau M, Mura T, Gabelle A, Courtet P, Ritchie K, Ancelin ML, Artero S. <strong>Late-life cynical hostility is associated with white matter alterations and the risk of Alzheimer&rsquo;s disease<\/strong>. Psychol Med. 2021 Apr 14:1-10. doi: 10.1017\/S0033291721000416.\u00a0<\/p>\n<p style=\"text-align: justify;\">Damotte V, van der Lee SJ, Chouraki V, Grenier-Boley B, Simino J, Adams H, Tosto G, White C, Terzikhan N, Cruchaga C, Knol MJ, Li S, Schraen S, Grove ML, Satizabal C, Amin N, Berr C, Younkin S; Alzheimer&rsquo;s Disease Neuroimaging Initiative, Gottesman RF, Bu\u00e9e L, Beiser A, Knopman DS, Uitterlinden A, DeCarli C, Bressler J, DeStefano A, Dartigues JF, Yang Q, Boerwinkle E, Tzourio C, Fornage M, Ikram MA, Amouyel P, de Jager P, Reitz C, Mosley TH, Lambert JC, Seshadri S, van Duijn CM. <strong>Plasma amyloid \u03b2 levels are driven by genetic variants near APOE, BACE1, APP, PSEN2: A genome-wide association study in over 12,000 non-demented participants<\/strong>. Alzheimers Dement. 2021 May 18. doi: 10.1002\/alz.12333.<\/p>\n<p style=\"text-align: justify;\">de Heus RAA, Tzourio C, Lee EJL, Opozda M, Vincent AD, Anstey KJ, Hofman A, Kario K, Lattanzi S, Launer LJ, Ma Y, Mahajan R, Mooijaart SP, Nagai M, Peters R, Turnbull D, Yano Y; VARIABLE BRAIN Consortium, Claassen JAHR, Tully PJ. <strong>Association Between Blood Pressure Variability With Dementia and Cognitive Impairment: A Systematic Review and Meta-Analysis<\/strong>. Hypertension. 2021;78(5):1478-1489. doi: 10.1161\/HYPERTENSIONAHA.121.17797. Epub 2021 Sep 20<\/p>\n<p style=\"text-align: justify;\">de Rojas I, Moreno-Grau S, Tesi N, Grenier-Boley B, Andrade V, Jansen IE, Pedersen NL, Stringa N, Zettergren A, Hern\u00e1ndez I, Montrreal L, Ant\u00fanez C, Antonell A, Tankard RM, Bis JC, Sims R, Bellenguez C, Quintela I, Gonz\u00e1lez-Perez A, Calero M, Franco-Mac\u00edas E, Mac\u00edas J, Blesa R, Cervera-Carles L, Men\u00e9ndez-Gonz\u00e1lez M, Frank-Garc\u00eda A, Royo JL, Moreno F, Huerto Vilas R, Baquero M, Diez-Fairen M, Lage C, Garc\u00eda-Madrona S, Garc\u00eda-Gonz\u00e1lez P, Alarc\u00f3n-Mart\u00edn E, Valero S, Sotolongo-Grau O, Ullgren A, Naj AC, Lemstra AW, Benaque A, P\u00e9rez-Cord\u00f3n A, Benussi A, R\u00e1bano A, Padovani A, Squassina A, de Mendon\u00e7a A, Arias Pastor A, Kok AAL, Meggy A, Pastor AB, Espinosa A, Corma-G\u00f3mez A, Mart\u00edn Montes A, Sanabria \u00c1, DeStefano AL, Schneider A, Haapasalo A, Kinhult St\u00e5hlbom A, Tybj\u00e6rg-Hansen A, Hartmann AM, Spottke A, Corbat\u00f3n-Anchuelo A, Rongve A, Borroni B, Arosio B, Nacmias B, Nordestgaard BG, Kunkle BW, Charbonnier C, Abdelnour C, Masullo C, Mart\u00ednez Rodr\u00edguez C, Mu\u00f1oz-Fernandez C, Dufouil C, Graff C, Ferreira CB, Chillotti C, Reynolds CA, Fenoglio C, Van Broeckhoven C, Clark C, Pisanu C, Satizabal CL, Holmes C, Buiza-Rueda D, Aarsland D, Rujescu D, Alcolea D, Galimberti D, Wallon D, Seripa D, Gr\u00fcnblatt E, Dardiotis E, D\u00fczel E, Scarpini E, Conti E, Rubino E, Gelpi E, Rodriguez-Rodriguez E, Duron E, Boerwinkle E, Ferri E, Tagliavini F, K\u00fc\u00e7\u00fckali F, Pasquier F, Sanchez-Garcia F, Mangialasche F, Jessen F, Nicolas G, Selb\u00e6k G, Ortega G, Ch\u00eane G, Hadjigeorgiou G, Rossi G, Spalletta G, Giaccone G, Grande G, Binetti G, Papenberg G, Hampel H, Bailly H, Zetterberg H, Soininen H, Karlsson IK, Alvarez I, Appollonio I, Giegling I, Skoog I, Saltvedt I, Rainero I, Rosas Allende I, Hort J, Diehl-Schmid J, Van Dongen J, Vidal JS, Lehtisalo J, Wiltfang J, Thomassen JQ, Kornhuber J, Haines JL, Vogelgsang J, Pineda JA, Fortea J, Popp J, Deckert J, Buerger K, Morgan K, Flie\u00dfbach K, Sleegers K, Molina-Porcel L, Kilander L, Weinhold L, Farrer LA, Wang LS, Kleineidam L, Farotti L, Parnetti L, Tremolizzo L, Hausner L, Benussi L, Froelich L, Ikram MA, Deniz-Naranjo MC, Tsolaki M, Rosende-Roca M, L\u00f6wenmark M, Hulsman M, Spallazzi M, Pericak-Vance MA, Esiri M, Bernal S\u00e1nchez-Arjona M, Dalmasso MC, Mart\u00ednez-Larrad MT, Arcaro M, N\u00f6then MM, Fern\u00e1ndez-Fuertes M, Dichgans M, Ingelsson M, Herrmann MJ, Scherer M, Vyhnalek M, Kosmidis MH, Yannakoulia M, Schmid M, Ewers M, Heneka MT, Wagner M, Scamosci M, Kivipelto M, Hiltunen M, Zulaica M, Alegret M, Fornage M, Roberto N, van Schoor NM, Seidu NM, Banaj N, Armstrong NJ, Scarmeas N, Scherbaum N, Goldhardt O, Hanon O, Peters O, Skrobot OA, Quenez O, Lerch O, Boss\u00f9 P, Caffarra P, Dionigi Rossi P, Sakka P, Hoffmann P, Holmans PA, Fischer P, Riederer P, Yang Q, Marshall R, Kalaria RN, Mayeux R, Vandenberghe R, Cecchetti R, Ghidoni R, Frikke-Schmidt R, Sorbi S, H\u00e4gg S, Engelborghs S, Helisalmi S, Botne Sando S, Kern S, Archetti S, Boschi S, Fostinelli S, Gil S, Mendoza S, Mead S, Ciccone S, Djurovic S, Heilmann-Heimbach S, Riedel-Heller S, Kuulasmaa T, Del Ser T, Lebouvier T, Polak T, Ngandu T, Grimmer T, Bessi V, Escott-Price V, Giedraitis V, Deramecourt V, Maier W, Jian X, Pijnenburg YAL; EADB contributors; GR@ACE study group; DEGESCO consortium; IGAP (ADGC, CHARGE, EADI, GERAD); PGC-ALZ consortia, Kehoe PG, Garcia-Ribas G, S\u00e1nchez-Juan P, Pastor P, P\u00e9rez-Tur J, Pi\u00f1ol-Ripoll G, Lopez de Munain A, Garc\u00eda-Alberca JM, Bullido MJ, \u00c1lvarez V, Lle\u00f3 A, Real LM, Mir P, Medina M, Scheltens P, Holstege H, Marqui\u00e9 M, S\u00e1ez ME, Carracedo \u00c1, Amouyel P, Schellenberg GD, Williams J, Seshadri S, van Duijn CM, Mather KA, S\u00e1nchez-Valle R, Serrano-R\u00edos M, Orellana A, T\u00e1rraga L, Blennow K, Huisman M, Andreassen OA, Posthuma D, Clarim\u00f3n J, Boada M, van der Flier WM, Ramirez A, Lambert JC, van der Lee SJ, Ruiz A. <strong>Common variants in Alzheimer&rsquo;s disease and risk stratification by polygenic risk scores.<\/strong> Nat Commun. 2021;12(1):3417. doi: 10.1038\/s41467-021-22491-8<\/p>\n<p style=\"text-align: justify;\">Du Preez A, Lef\u00e8vre-Arbogast S, Houghton V, de Lucia C, Low DY, Helmer C, F\u00e9art C, Delcourt C, Proust-Lima C, Pall\u00e0s M, Ruigrok SR, Altendorfer B, Gonz\u00e1lez-Dom\u00ednguez R, S\u00e1nchez-Pla A, Urpi-Sard\u00e0 M, Andres-Lacueva C, Aigner L, Lucassen PJ, Korosi A, Manach C, Samieri C, Thuret S. <strong>The serum metabolome mediates the concert of diet, exercise, and neurogenesis, determining the risk for cognitive decline and dementia<\/strong>. Alzheimers Dement. 2021 Aug 17. doi: 10.1002\/alz.12428. Online ahead of print.<\/p>\n<p style=\"text-align: justify;\">Dupr\u00e9 C, Helmer C, Bongue B, Dartigues JF, Roche F, Berr C, Carri\u00e8re I. <strong>Associations between physical activity types and multi-domain cognitive decline in older adults from the Three-city cohort<\/strong>. PLoS One. 2021;16(6):e0252500. eCollection 2021<\/p>\n<p style=\"text-align: justify;\">Georges A, Yang ML, Berrandou TE, Bakker MK, Dikilitas O, Kiando SR, Ma L, Satterfield BA, Sengupta S, Yu M, Deleuze JF, Dupr\u00e9 D, Hunker KL, Kyryachenko S, Liu L, Sayoud-Sadeg I, Amar L, Brummett CM, Coleman DM, d&rsquo;Escamard V, de Leeuw P, Fendrikova-Mahlay N, Kadian-Dodov D, Li JZ, Lorthioir A, Pappaccogli M, Prejbisz A, Smigielski W, Stanley JC, Zawistowski M, Zhou X, Z\u00f6llner S; FEIRI investigators; International Stroke Genetics Consortium (ISGC) Intracranial Aneurysm Working Group; MEGASTROKE, Amouyel P, De Buyzere ML, Debette S, Dobrowolski P, Drygas W, Gornik HL, Olin JW, Piwonski J, Rietzschel ER, Ruigrok YM, Vikkula M, Warchol Celinska E, Januszewicz A, Kullo IJ, Azizi M, Jeunemaitre X, Persu A, Kovacic JC, Ganesh SK, Bouatia-Naji N. <strong>Genetic investigation of fibromuscular dysplasia identifies risk loci and shared genetics with common cardiovascular diseases<\/strong>. Nat Commun. 2021;12(1):6031<\/p>\n<p style=\"text-align: justify;\">Gomez-Cabrero D, Walter S, Abugessaisa I, Mi\u00f1ambres-Herraiz R, Palomares LB, Butcher L, Erusalimsky JD, Garcia-Garcia FJ, Carnicero J, Hardman TC, Mischak H, Z\u00fcrbig P, Hackl M, Grillari J, Fiorillo E, Cucca F, Cesari M, Carrie I, Colpo M, Bandinelli S, Feart C, Peres K, Dartigues JF, Helmer C, Vi\u00f1a J, Olaso G, Garc\u00eda-Palmero I, Mart\u00ednez JG, Jansen-D\u00fcrr P, Grune T, Weber D, Lippi G, Bonaguri C, Sinclair AJ, Tegner J, Rodriguez-Ma\u00f1as L; FRAILOMIC initiative. <strong>A robust machine learning framework to identify signatures for frailty: a nested case-control study in four aging European cohorts<\/strong>. Geroscience. 2021;43(3):1317-1329. Epub 2021 Feb 18<\/p>\n<p style=\"text-align: justify;\">Gonz\u00e1lez-Dom\u00ednguez R, Castellano-Escuder P, Carmona F, Lef\u00e8vre-Arbogast S, Low DY, Du Preez A, Ruigrok SR, Manach C, Urpi-Sarda M, Korosi A, Lucassen PJ, Aigner L, Pall\u00e0s M, Thuret S, Samieri C, S\u00e1nchez-Pla A, Andres-Lacueva C. <strong>Food and Microbiota Metabolites Associate with Cognitive Decline in Older Subjects: A 12-Year Prospective Study<\/strong>. Mol Nutr Food Res. 2021;65(23):e2100606. doi: 10.1002\/mnfr.202100606. Epub 2021 Oct 28<\/p>\n<p style=\"text-align: justify;\">Harris WS, Tintle NL, Imamura F, Qian F, Korat AVA, Marklund M, Djouss\u00e9 L, Bassett JK, Carmichael PH, Chen YY, Hirakawa Y, K\u00fcpers LK, Laguzzi F, Lankinen M, Murphy RA, Samieri C, Senn MK, Shi P, Virtanen JK, Brouwer IA, Chien KL, Eiriksdottir G, Forouhi NG, Geleijnse JM, Giles GG, Gudnason V, Helmer C, Hodge A, Jackson R, Khaw KT, Laakso M, Lai H, Laurin D, Leander K, Lindsay J, Micha R, Mursu J, Ninomiya T, Post W, Psaty BM, Ris\u00e9rus U, Robinson JG, Shadyab AH, Snetselaar L, Sala-Vila A, Sun Y, Steffen LM, Tsai MY, Wareham NJ, Wood AC, Wu JHY, Hu F, Sun Q, Siscovick DS, Lemaitre RN, Mozaffarian D; Fatty Acids and Outcomes Research Consortium (FORCE). <strong>Blood n-3 fatty acid levels and total and cause-specific mortality from 17 prospective studies.<\/strong> Nat Commun. 2021;12(1):2329.<\/p>\n<p style=\"text-align: justify;\">Hern\u00e1ndez-Ruiz V, Meillon C, Avila-Funes JA, Bergua V, Dartigues JF, Koleck M, Letenneur L, Ouvrard C, P\u00e9r\u00e8s K, Rascle N, Tabue-Teguo M, Amieva H. <strong>Older Adults and the COVID-19 Pandemic, What About the Oldest Old? The PACOVID Population-Based Survey<\/strong>. Front Psychiatry. 2021;12:711583. eCollection 2021<\/p>\n<p style=\"text-align: justify;\">Lef\u00e8vre-Arbogast S, Hejblum BP, Helmer C, Klose C, Manach C, Low DY, Urpi-Sarda M, Andres-Lacueva C, Gonz\u00e1lez-Dom\u00ednguez R, Aigner L, Altendorfer B, Lucassen PJ, Ruigrok SR, De Lucia C, Du Preez A, Proust-Lima C, Thuret S, Korosi A, Samieri C. E<strong>arly signature in the blood lipidome associated with subsequent cognitive decline in the elderly: A case-control analysis nested within the Three-City cohort study<\/strong>. EBioMedicine. 2021 Feb;64:103216. Epub 2021 Jan 25<\/p>\n<p style=\"text-align: justify;\">Le Grand Q, Satizabal CL, Sargurupremraj M, Mishra A, Soumar\u00e9 A, Laurent A, Crivello F, Tsuchida A, Shin J, Macalli M, Singh B, Beiser AS, DeCarli C, Fletcher E, Paus T, Lathrop M, Adams HHH, Bis JC, Seshadri S, Tzourio C, Mazoyer B, Debette S. <strong>Genomic studies across the lifespan point to early mechanisms determining subcortical volumes.<\/strong> Biol Psychiatry Cogn Neurosci Neuroimaging. 2021 Oct 23:S2451-9022(21)00286-X. doi: 10.1016\/j.bpsc.2021.10.011<\/p>\n<p style=\"text-align: justify;\">Letellier N, Ilango SD, Mortamais M, Tzourio C, Gabelle A, Empana JP, Samieri C, Berr C, Benmarhnia T. <strong>Socioeconomic inequalities in dementia risk among a French population-based cohort: quantifying the role of cardiovascular health and vascular events<\/strong>. Eur J Epidemiol. 2021;36(10):1015-1023. Epub 2021 Jul 25<\/p>\n<p style=\"text-align: justify;\">Linard M, Baillet M, Letenneur L, Garrigue I, Catheline G, Dartigues JF, Peres K, Helmer C. <strong>Herpes simplex virus, early neuroimaging markers and incidence of Alzheimer&rsquo;s disease<\/strong>. Transl Psychiatry. 2021;11(1):414. doi: 10.1038\/s41398-021-01532-2<\/p>\n<p style=\"text-align: justify;\">Madrid L, Moreno-Grau S, Ahmad S, Gonz\u00e1lez-P\u00e9rez A, de Rojas I, Xia R, Martino Adami PV, Garc\u00eda-Gonz\u00e1lez P, Kleineidam L, Yang Q, Damotte V, Bis JC, Noguera-Perea F, Bellenguez C, Jian X, Mar\u00edn-Mu\u00f1oz J, Grenier-Boley B, Orellana A, Ikram MA, Amouyel P, Satizabal CL; Alzheimer\u2019s Disease Neuroimaging Initiative (ADNI)*; EADI consortium, CHARGE consortium, GERAD consortium, GR@ACE\/DEGESCO consortium, Real LM, Ant\u00fanez-Almagro C, DeStefano A, Cabrera-Socorro A, Sims R, Van Duijn CM, Boerwinkle E, Ram\u00edrez A, Fornage M, Lambert JC, Williams J, Seshadri S; ADAPTED consortium, Ried JS, Ruiz A, Saez ME. <strong>Multiomics integrative analysis identifies APOE allele-specific blood biomarkers associated to Alzheimer&rsquo;s disease etiopathogenesis.<\/strong> Aging (Albany NY). 2021;13(7):9277-9329. Online ahead of print<\/p>\n<p style=\"text-align: justify;\">Mauschitz MM, Schmitz MT, Verzijden T, Schmid M, Thee EF, Colijn JM, Delcourt C, Cougnard-Gr\u00e9goire A, Merle BMJ, Korobelnik JF, Gopinath B, Mitchell P, Elbaz H, Schuster AK, Wild PS, Brandl C, Stark KJ, Heid IM, G\u00fcnther F, Peters A, Klaver CCW, Finger RP; European Eye Epidemiology (E3) Consortium. <strong>Physical Activity, Incidence, and Progression of Age-Related Macular Degeneration: A Multicohort Study<\/strong>. Am J Ophthalmol. 2021 Oct 22;236:99-106. doi: 10.1016\/j.ajo.2021.10.008.<\/p>\n<p style=\"text-align: justify;\">Merle BMJ, Cougnard-Gr\u00e9goire A, Korobelnik JF, Schalch W, Etheve S, Rougier MB, F\u00e9art C, Samieri C, Delyfer MN, Delcourt C. <strong>Plasma Lutein, a Nutritional Biomarker for Development of Advanced Age-Related Macular Degeneration: The Alienor Study<\/strong>. Nutrients. 2021 Jun 15;13(6):2047. doi: 10.3390\/nu13062047<\/p>\n<p style=\"text-align: justify;\">Morillon C, Le Goff M, Gattoussi S, Korobelnik JF, Rougier MB, Schweitzer C, Delcourt C, Delyfer MN.<strong> Incidence, progression and risk factors of epiretinal membranes in the elderly<\/strong>. Retina. 2021 Mar 1;41(3):495-504.<\/p>\n<p style=\"text-align: justify;\">Mortamais M, Gutierrez LA, de Hoogh K, Chen J, Vienneau D, Carri\u00e8re I, Letellier N, Helmer C, Gabelle A, Mura T, Sunyer J, Benmarhnia T, Jacquemin B, Berr C. <strong>Long-term exposure to ambient air pollution and risk of dementia: Results of the prospective Three-City Study<\/strong>. Environ Int. 2021;148:106376. Epub 2021 Jan 2<\/p>\n<p style=\"text-align: justify;\">NCD Risk Factor Collaboration (NCD-RisC). <strong>Worldwide trends in hypertension prevalence and progress in treatment and control from 1990 to 2019: a pooled analysis of 1201 population-representative studies with 104 million participants<\/strong>. Lancet. 2021;398(10304):957-980. Epub 2021 Aug 24<\/p>\n<p style=\"text-align: justify;\">NCD Risk Factor Collaboration (NCD-RisC). <strong>Heterogeneous contributions of change in population distribution of body mass index to change in obesity and underweight<\/strong>. Elife. 2021;10:e60060. doi: 10.7554\/eLife.60060<\/p>\n<p style=\"text-align: justify;\">P\u00e9r\u00e8s K, Ouvrard C, Koleck M, Rascle N, Dartigues JF, Bergua V, Amieva H. <strong>Living in rural area: A protective factor for a negative experience of the lockdown and the COVID-19 crisis in the oldest old population? <\/strong>Int J Geriatr Psychiatry. 2021;36(12):1950-1958. Epub 2021 Aug 26.<\/p>\n<p style=\"text-align: justify;\">Peters R, Xu Y, Antikainen R, Beckett N, Gussekloo J, Jagger C, Jukema JW, Keinanen-Kiukaanniemi S, Ryd\u00e9n L, Skoog I, Staessen JA, Thijs L, Trompet S, Tully PJ, Tzourio C, Anstey KJ. <strong>Evaluation of High Cholesterol and Risk of Dementia and Cognitive Decline in Older Adults Using Individual Patient Meta-Analysis<\/strong>. Dement Geriatr Cogn Disord. 2021;50(4):318-325. Epub 2021 Oct 26<\/p>\n<p style=\"text-align: justify;\">Pilleron S, Le Goff M, Ajana S, Helmer C, P\u00e9r\u00e8s K, Dartigues JF, Tabue-Teguo M, F\u00e9art C. <strong>Self-Rated Health and Frailty in Older Adults from the Population-Based Three-City Bordeaux Cohort. Gerontology<\/strong>. 2021 Oct 18:1-8. doi: 10.1159\/000518864. Online ahead of print.<\/p>\n<p style=\"text-align: justify;\">Pin G, Coup\u00e9 P, Nadal L, Manjon JV, Helmer C, Amieva H, Mazoyer B, Dartigues JF, Catheline G, Planche V. <strong>Distinct Hippocampal Subfields Atrophy in Older People With Vascular Brain Injuries<\/strong>. Stroke. 2021;52(5):1741-1750. Epub 2021 Mar 4<\/p>\n<p style=\"text-align: justify;\">Qian F, Ardisson Korat AV, Imamura F, Marklund M, Tintle N, Virtanen JK, Zhou X, Bassett JK, Lai H, Hirakawa Y, Chien KL, Wood AC, Lankinen M, Murphy RA, Samieri C, Pertiwi K, de Mello VD, Guan W, Forouhi NG, Wareham N, Hu ICFB, Riserus U, Lind L, Harris WS, Shadyab AH, Robinson JG, Steffen LM, Hodge A, Giles GG, Ninomiya T, Uusitupa M, Tuomilehto J, Lindstr\u00f6m J, Laakso M, Siscovick DS, Helmer C, Geleijnse JM, Wu JHY, Fretts A, Lemaitre RN, Micha R, Mozaffarian D, Sun Q; Fatty Acids and Outcomes Research Consortium (FORCE). <strong>n-3 Fatty Acid Biomarkers and Incident Type 2 Diabetes: An Individual Participant-Level Pooling Project of 20 Prospective Cohort Studies. Diabetes Care.<\/strong> 2021;44(5):1133-1142. Epub 2021 Mar 3<\/p>\n<p style=\"text-align: justify;\">Rahi B, Pellay H, Chuy V, Helmer C, Samieri C, F\u00e9art C. <strong>Dairy Product Intake and Long-Term Risk for Frailty among French Elderly Community Dwellers.<\/strong> Nutrients. 2021;13(7):2151.<\/p>\n<p style=\"text-align: justify;\">Rouanet A, Avila-Rieger J, Dugravot A, Lespinasse J, Stuckwisch R, Merrick R, Anderson E, Long L, Helmer C, Jacqmin-Gadda H, Dufouil C, Judd S, Manly J, Sabia S, Gross A, Proust-Lima C. <strong>How Selection Over Time Contributes to the Inconsistency of the Association between Sex\/Gender and Cognitive Decline across Cognitive Aging Cohorts<\/strong>. Am J Epidemiol. 2021 Sep 14:kwab227. Online ahead of print.<\/p>\n<p style=\"text-align: justify;\">Thomas A, Crivello F, Mazoyer B, Debette S, Tzourio C, Samieri C. <strong>Fish Intake and MRI Burden of Cerebrovascular Disease in Older Adults.<\/strong> Neurology. 2021;97(22):e2213-e2222. Epub 2021 Nov 3<\/p>\n<p style=\"text-align: justify;\">Thomas A, Proust-Lima C, Baillet M, Helmer C, Delcourt C, Foubert-Samier A, Catheline G, F\u00e9art C, Samieri C. <strong>Plasma carotenoids and medial temporal lobe atrophy in older adults<\/strong>. Clin Nutr. 2021;40(4):2460-2463. Epub 2020 Oct 14.<\/p>\n<p style=\"text-align: justify;\">van Rheenen W, van der Spek RAA, Bakker MK, van Vugt JJFA, Hop PJ, Zwamborn RAJ, de Klein N, Westra HJ, Bakker OB, Deelen P, Shireby G, Hannon E, Moisse M, Baird D, Restuadi R, Dolzhenko E, Dekker AM, Gawor K, Westeneng HJ, Tazelaar GHP, van Eijk KR, Kooyman M, Byrne RP, Doherty M, Heverin M, Al Khleifat A, Iacoangeli A, Shatunov A, Ticozzi N, Cooper-Knock J, Smith BN, Gromicho M, Chandran S, Pal S, Morrison KE, Shaw PJ, Hardy J, Orrell RW, Sendtner M, Meyer T, Ba\u015fak N, van der Kooi AJ, Ratti A, Fogh I, Gellera C, Lauria G, Corti S, Cereda C, Sproviero D, D&rsquo;Alfonso S, Sorar\u00f9 G, Siciliano G, Filosto M, Padovani A, Chi\u00f2 A, Calvo A, Moglia C, Brunetti M, Canosa A, Grassano M, Beghi E, Pupillo E, Logroscino G, Nefussy B, Osmanovic A, Nordin A, Lerner Y, Zabari M, Gotkine M, Baloh RH, Bell S, Vourc&rsquo;h P, Corcia P, Couratier P, Millecamps S, Meininger V, Salachas F, Mora Pardina JS, Assialioui A, Rojas-Garc\u00eda R, Dion PA, Ross JP, Ludolph AC, Weishaupt JH, Brenner D, Freischmidt A, Bensimon G, Brice A, Durr A, Payan CAM, Saker-Delye S, Wood NW, Topp S, Rademakers R, Tittmann L, Lieb W, Franke A, Ripke S, Braun A, Kraft J, Whiteman DC, Olsen CM, Uitterlinden AG, Hofman A, Rietschel M, Cichon S, N\u00f6then MM, Amouyel P; SLALOM Consortium; PARALS Consortium; SLAGEN Consortium; SLAP Consortium, Traynor BJ, Singleton AB, Mitne Neto M, Cauchi RJ, Ophoff RA, Wiedau-Pazos M, Lomen-Hoerth C, van Deerlin VM, Grosskreutz J, Roediger A, Gaur N, J\u00f6rk A, Barthel T, Theele E, Ilse B, Stubendorff B, Witte OW, Steinbach R, H\u00fcbner CA, Graff C, Brylev L, Fominykh V, Demeshonok V, Ataulina A, Rogelj B, Koritnik B, Zidar J, Ravnik-Glava\u010d M, Glava\u010d D, Stevi\u0107 Z, Drory V, Povedano M, Blair IP, Kiernan MC, Benyamin B, Henderson RD, Furlong S, Mathers S, McCombe PA, Needham M, Ngo ST, Nicholson GA, Pamphlett R, Rowe DB, Steyn FJ, Williams KL, Mather KA, Sachdev PS, Henders AK, Wallace L, de Carvalho M, Pinto S, Petri S, Weber M, Rouleau GA, Silani V, Curtis CJ, Breen G, Glass JD, Brown RH Jr, Landers JE, Shaw CE, Andersen PM, Groen EJN, van Es MA, Pasterkamp RJ, Fan D, Garton FC, McRae AF, Davey Smith G, Gaunt TR, Eberle MA, Mill J, McLaughlin RL, Hardiman O, Kenna KP, Wray NR, Tsai E, Runz H, Franke L, Al-Chalabi A, Van Damme P, van den Berg LH, Veldink JH. <strong>Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology. Nat Genet.<\/strong> 2021 Dec;53(12):1636-1648. Epub 2021 Dec 6.<\/p>\n<p style=\"text-align: justify;\">Yu M, Kyryachenko S, Debette S, Amouyel P, Schott JJ, Le Tourneau T, Dina C, Norris RA, Hag\u00e8ge AA, Jeunemaitre X, Bouatia-Naji N. <strong>Genome-Wide Association Meta-Analysis Supports Genes Involved in Valve and Cardiac Development to Associate With Mitral Valve Prolapse<\/strong>. Circ Genom Precis Med. 2021;14(5):e003148. Epub 2021 Aug 31<\/p>\n<\/div><\/div><\/div><\/div><\/div><style type=\"text\/css\">.fusion-accordian  #accordion-880-21 .panel-title a .fa-fusion-box{ color: #ffffff;}.fusion-accordian  #accordion-880-21 .panel-title a .fa-fusion-box:before{ font-size: 16px; width: 16px;}.fusion-accordian  #accordion-880-21 .panel-title a{font-size:24px;}.fusion-accordian  #accordion-880-21 .fa-fusion-box { background-color: #212934;border-color: #212934;}.fusion-accordian  #accordion-880-21 .panel-title a:hover, #accordion-880-21 .fusion-toggle-boxed-mode:hover .panel-title a { color: #65bc7b;}.fusion-accordian  #accordion-880-21 .panel-title .active .fa-fusion-box,.fusion-accordian  #accordion-880-21 .panel-title a:hover .fa-fusion-box { background-color: #65bc7b!important;border-color: #65bc7b!important;}<\/style><div class=\"accordian fusion-accordian\"><div class=\"panel-group\" id=\"accordion-880-21\"><div class=\"fusion-panel panel-default\"><div class=\"panel-heading\"><h4 class=\"panel-title toggle\"><a aria-expanded=\"false\" aria-controls=\"482346a3ebe2d0af0\" role=\"button\" data-toggle=\"collapse\" data-parent=\"#accordion-880-21\" data-target=\"#482346a3ebe2d0af0\" href=\"#482346a3ebe2d0af0\"><span class=\"fusion-toggle-icon-wrapper\" aria-hidden=\"true\"><i class=\"fa-fusion-box\" aria-hidden=\"true\"><\/i><\/span><span class=\"fusion-toggle-heading\">2022<\/span><\/a><\/h4><\/div><div id=\"482346a3ebe2d0af0\" class=\"panel-collapse collapse \"><div class=\"panel-body toggle-content fusion-clearfix\">\n<p style=\"text-align: justify;\">Bordes C, Sargurupremraj M, Mishra A, Debette S. <strong>Genetics of common cerebral small vessel disease<\/strong>. Nat Rev Neurol. 2022 Jan 5. doi: 10.1038\/s41582-021-00592-8. Online ahead of print<\/p>\n<p style=\"text-align: justify;\">Cavaill\u00e8s C, Berr C, Helmer C, Gabelle A, Jaussent I, Dauvilliers Y. <strong>Complaints of daytime sleepiness, insomnia, hypnotic use, and risk of dementia: a prospective cohort study in the elderly.<\/strong> Alzheimers Res Ther. 2022;14(1):12<\/p>\n<p style=\"text-align: justify;\">Chuy V, Gentreau M, Artero S, Berticat C, Rigalleau V, P\u00e9r\u00e8s K, Helmer C, Samieri C, F\u00e9art C. <strong>Simple Carbohydrate Intake and Higher Risk for Physical Frailty Over 15 Years in Community-Dwelling Older Adults.<\/strong> J Gerontol A Biol Sci Med Sci. 2022;77(1):10-18.<\/p>\n<p style=\"text-align: justify;\">Dartigues JF, Le Bourdonnec K, Tabue-Teguo M, Le Goff M, Helmer C, Avila-Funes JA, Coureau G, Feart C, P\u00e9r\u00e8s K, Genuer R, Letenneur L, Amieva H, Proust-Lima C. <strong>Co-Occurrence of Geriatric Syndromes and Diseases in the General Population: Assessment of the Dimensions of Aging<\/strong>. J Nutr Health Aging. 2022;26(1):37-45.<\/p>\n<p style=\"text-align: justify;\">Duchesne J, Gutierrez LA, Carri\u00e8re I, Mura T, Chen J, Vienneau D, de Hoogh K, Helmer C, Jacquemin B, Berr C, Mortamais M. <strong>Exposure to ambient air pollution and cognitive decline: Results of the prospective Three-City cohort study<\/strong>. Environ Int. 2022 Feb 3;161:107118. doi: 10.1016\/j.envint.2022.107118. Online ahead of print<\/p>\n<p style=\"text-align: justify;\">Gonz\u00e1lez-Dom\u00ednguez R, Castellano-Escuder P, Lef\u00e8vre-Arbogast S, Low DY, Du Preez A, Ruigrok SR, Lee H, Helmer C, Pall\u00e0s M, Urpi-Sarda M, S\u00e1nchez-Pla A, Korosi A, Lucassen PJ, Aigner L, Manach C, Thuret S, Samieri C, Andres-Lacueva C. <strong>Apolipoprotein E and sex modulate fatty acid metabolism in a prospective observational study of cognitive decline<\/strong>. Alzheimers Res Ther. 2022 Jan 3;14(1):1. doi: 10.1186\/s13195-021-00948-8<\/p>\n<p style=\"text-align: justify;\">Letellier N, Gutierrez LA, Duchesne J, Chen C, Ilango S, Helmer C, Berr C, Mortamais M, Benmarhnia T.<strong> Air quality improvement and incident dementia: Effects of observed and hypothetical reductions in air pollutant using parametric g-computation<\/strong>. Alzheimers Dement. 2022 Feb 9. doi: 10.1002\/alz.12606. Online ahead of print.<\/p>\n<p style=\"text-align: justify;\">Neuffer J, Gourru M, Thomas A, Lef\u00e8vre-Arbogast S, Foubert-Samier A, Helmer C, Delcourt C, F\u00e9art C, Samieri C. <strong>A Biological Index to Screen Multi-Micronutrient Deficiencies Associated with the Risk to Develop Dementia in Older Persons from the Community<\/strong>. J Alzheimers Dis. 2022;85(1):331-342.<\/p>\n<p style=\"text-align: justify;\">Pavlik VN, Burnham SC, Kass JS, Helmer C, Palmqvist S, Vassilaki M, Dartigues JF, Hansson O, Masters CL, P\u00e9r\u00e8s K, Petersen RC, Stomrud E, Butler L, Coloma PM, Teitsma XM, Doody R, Sano M; CONCORD-AD investigators. <strong>Connecting Cohorts to Diminish Alzheimer&rsquo;s Disease (CONCORD-AD): A Report of an International Research Collaboration Network<\/strong>. J Alzheimers Dis. 2022;85(1):31-45. <\/p>\n<\/div><\/div><\/div><\/div><\/div><\/div><style type=\"text\/css\">.fusion-body .fusion-builder-column-6{width:100% !important;margin-top : 0px;margin-bottom : 0px;}.fusion-builder-column-6 > .fusion-column-wrapper {padding-top : 0px !important;padding-right : 0px !important;margin-right : 1.92%;padding-bottom : 85px !important;padding-left : 0px !important;margin-left : 1.92%;}@media only screen and (max-width:1024px) {.fusion-body .fusion-builder-column-6{width:100% !important;order : 0;}.fusion-builder-column-6 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}@media only screen and (max-width:640px) {.fusion-body .fusion-builder-column-6{width:100% !important;order : 0;}.fusion-builder-column-6 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}<\/style><\/div><\/div><style type=\"text\/css\">.fusion-fullwidth.fusion-builder-row-3 a:not(.awb-custom-text-color):not(.fusion-button):not(.fusion-builder-module-control):not(.fusion-social-network-icon):not(.fb-icon-element):not(.fusion-countdown-link):not(.fusion-rollover-link):not(.fusion-rollover-gallery):not(.fusion-button-bar):not(.add_to_cart_button):not(.show_details_button):not(.product_type_external):not(.fusion-view-cart):not(.fusion-quick-view):not(.fusion-rollover-title-link):not(.fusion-breadcrumb-link) , .fusion-fullwidth.fusion-builder-row-3 a:not(.awb-custom-text-color):not(.fusion-button):not(.fusion-builder-module-control):not(.fusion-social-network-icon):not(.fb-icon-element):not(.fusion-countdown-link):not(.fusion-rollover-link):not(.fusion-rollover-gallery):not(.fusion-button-bar):not(.add_to_cart_button):not(.show_details_button):not(.product_type_external):not(.fusion-view-cart):not(.fusion-quick-view):not(.fusion-rollover-title-link):not(.fusion-breadcrumb-link):before, .fusion-fullwidth.fusion-builder-row-3 a:not(.awb-custom-text-color):not(.fusion-button):not(.fusion-builder-module-control):not(.fusion-social-network-icon):not(.fb-icon-element):not(.fusion-countdown-link):not(.fusion-rollover-link):not(.fusion-rollover-gallery):not(.fusion-button-bar):not(.add_to_cart_button):not(.show_details_button):not(.product_type_external):not(.fusion-view-cart):not(.fusion-quick-view):not(.fusion-rollover-title-link):not(.fusion-breadcrumb-link):after {color: #035ac3;}.fusion-fullwidth.fusion-builder-row-3 a:not(.awb-custom-text-hover-color):not(.fusion-button):not(.fusion-builder-module-control):not(.fusion-social-network-icon):not(.fb-icon-element):not(.fusion-countdown-link):not(.fusion-rollover-link):not(.fusion-rollover-gallery):not(.fusion-button-bar):not(.add_to_cart_button):not(.show_details_button):not(.product_type_external):not(.fusion-view-cart):not(.fusion-quick-view):not(.fusion-rollover-title-link):not(.fusion-breadcrumb-link):hover, .fusion-fullwidth.fusion-builder-row-3 a:not(.awb-custom-text-hover-color):not(.fusion-button):not(.fusion-builder-module-control):not(.fusion-social-network-icon):not(.fb-icon-element):not(.fusion-countdown-link):not(.fusion-rollover-link):not(.fusion-rollover-gallery):not(.fusion-button-bar):not(.add_to_cart_button):not(.show_details_button):not(.product_type_external):not(.fusion-view-cart):not(.fusion-quick-view):not(.fusion-rollover-title-link):not(.fusion-breadcrumb-link):hover:before, .fusion-fullwidth.fusion-builder-row-3 a:not(.awb-custom-text-hover-color):not(.fusion-button):not(.fusion-builder-module-control):not(.fusion-social-network-icon):not(.fb-icon-element):not(.fusion-countdown-link):not(.fusion-rollover-link):not(.fusion-rollover-gallery):not(.fusion-button-bar):not(.add_to_cart_button):not(.show_details_button):not(.product_type_external):not(.fusion-view-cart):not(.fusion-quick-view):not(.fusion-rollover-title-link):not(.fusion-breadcrumb-link):hover:after {color: #73c221;}.fusion-fullwidth.fusion-builder-row-3 .pagination a.inactive:hover, .fusion-fullwidth.fusion-builder-row-3 .fusion-filters .fusion-filter.fusion-active a {border-color: #73c221;}.fusion-fullwidth.fusion-builder-row-3 .pagination .current {border-color: #73c221; 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