Publications

Alpérovitch A, Amouyel P, Dartigues JF, Ducimetière P, Mazoyer B, Ritchie K, Tzourio C. Epidemiological studies on aging in France: from the PAQUID study to the Three-City study. C R Biol. 2002;325(6):665-72. Review. French

Larrieu S, Letenneur L, Berr C, Dartigues JF, Ritchie K, Alpérovitch A, Tavernier B, Barberger-Gateau P. Sociodemographic differences in dietary habits in a population-based sample of elderly subjects in the 3C Study. J Nutr Health Aging 2004; 8:497-502.

Larrieu S, Pérès K, Letenneur L, Berr C, Dartigues JF, Ritchie K, Février B, Alpérovitch A, Barberger-Gateau P. Relationship between body mass index and different domains of disability in older persons: The 3C Study. Int J Obes Relat Metab Disord 2004; 28:1555-60.

Ritchie K, Artero S, Beluche I, Ancelin ML, Mann A, Dupuy AM, Malafosse A, Boulenger JP. Prevalence of DSM-IV psychiatric disorder in the French elderly population. Br J Psychiatry. 2004 Feb;184:147-52. (Esprit cohort, subgroup of Montpellier 3C).

Zureik M, Gariépy J, Courbon D, Dartigues JF, Ritchie K, Tzourio C,
Alpérovitch A, Simon A, Ducimetière P. Alcohol consumption and large artery structure in older French adults. The Three-City Study. Stroke 2004; 35:2770-2775.

Barberger-Gateau P, Jutand MA, Letenneur L, Larrieu S, Berr C, Tavernier B and the Three-City Study Investigators. Correlates of regular fish consumption in French elderly community dwellers: data from the Three-City study. Eur J Clin Nutrition 2005; 59:817-825.

Cowppli-Bony P, Fabrigoule C, Letenneur et al. Validity of the five-word screening test for Alzheimer’s disease in a population-based study. Rev Neurol (Paris) 2005; 161:1205-1212.

De Bisschop C, Marty ML, Tessier JF, Barberger-Gateau P, Dartigues JF, Guénard H. Expiratory flow limitation and obstruction in the elderly. Eur Respir J 2005; 26:594-601.

Dufouil C*, Richard F*, Fiévet N, Dartigues JF, Ritchie K, Tzourio C, Amouyel P, Alpérovitch A. APOE genotype, cholesterol level, lipid-lowering treatment and dementia. The Three-City Study. Neurology 2005; 64:1531-1538.

Elbaz A, Ripert M, Tavernier B, Février B, Zureik M, Gariépy J, Alpérovitch A, Tzourio C. Common carotid artery intima-media thickness, carotid plaques, and walking speed. Stroke 2005; 36:2198-2202.

Feart C, Pallet V, Boucheron C, Higueret D, Alfos S, Letenneur L, Dartigues JF, Higueret P. Aging affects the retinoic acid and the triiodothyronine nuclear receptor mRNA expression in human peripheral blood mononuclear cells.Eur J Endocrinol 2005 Mar;152(3):449-58

Lechevallier-Michel N, Gautier-Bertrand M, Alpérovitch A, Berr C, Belmin J, Legrain S, Saint-Jean O, Tavernier B, Dartigues JF, Fourrier-Régalat A. Frequency and risk factors of potentially inappropriate medication use in a French community-dwelling elderly population: Results from the 3C Study. Eur J Clin Pharmacol 2005; 60:813-819.

Artero S, Astruc B, Courtet P, Ritchie K. Life-time history of suicide attempts and coronary artery disease in a community-dwelling elderly population. International Journal of Geriatric Psychiatry 2006; 21:108-112.

Brindel P, Hanon O,  Dartigues JF, Ritchie K, Lacombe JM, Alpérovitch A, Tzourio C for the 3C Study investigators. Prevalence, awareness, treatment and control of hypertension in the elderly. The Three-City Study. J Hypertension 2006; 24:51-58.

Debette S, Lambert JC, Gariépy J, Fievet N, Tzourio C, Dartigues JF, Ritchie K, Dupuy AM, Alpérovitch A, Ducimetière P, Amouyel P, Zureik M. New insight into the association of apoE genetic variants with carotid plaques and intima-media thickness. Stroke 2006; 37:2917-2923.

Harrabi I, Rondeau V, Dartigues JF et al. Effects of particulate air pollution on systolic blood pressure:A population-based approach. Environ Res 2006; 101:89-93.

Soumaré A, Elbaz E, Ducros V, Tavernier B, Alpérovitch A ,Tzourio C. Homocysteine and the motor function in the elderly – The Three-City Study. Neurology 2006; 67:285-290.

Amieva H, Carcaillon L, Rouze L’Alzit-Schuermans P, Millet X, Dartigues JF, Fabrigoule C. Cued and uncued memory tests: norms in elderly adults from the 3 Cities epidemiological study.Rev Neurol (Paris). 2007;163(2):205-21. French

Barberger-Gateau P, Raffaitin C, Letenneur L, Berr C, Tzourio C, Dartigues JF, Alpérovitch A. Dietary patterns and risk of dementia: the Three-City cohort study. Neurology 2007; 69:1921-1930.

Bourdel-Marchasson I, Helmer C, Barberger-Gateau P, Peuchant E, Février B, Ritchie K, Dartigues JF. Characteristics of undiagnosed diabetes in community dwelling French elderly: The 3C study. Diabetes Research and Clinical Practice 2007; 76:257-264.

Empana JP, Zureik M, Gariépy J, Courbon D, Dartigues JF, Ritchie K, Tzourio C, Alpérovitch A, Ducimetière P. Metabolic syndrome and carotid artery structure in non-institutionalized elderly subjects-The Three-City Study. Stroke 2007; 38:893-899.

Feart C, Jutand MA, Larrieu S, Letenneur L, Delcourt C, Combe C, Barberger-Gateau P. Energy, macronutrient and fatty acid intake of French elderly community dwellers and association with socio-demographic characteristics: data from the 3C-Bordeaux sample of the Three-City Study. Br J Nutrition 2007; 98:1046-1057.

Godin O, Dufouil C, Ritchie K, Dartigues JF, Tzourio C, Alpérovitch A. Depressive symptoms, major depressive episode and cognition il the elderly: the Three-City Study. Neuroepidemiology 2007; 28:101-108.

Ritchie K, Carrière I, Portet F, de Mendoca A, Dartigues JF, Rouaud 0, Barberger-Gateau P, Ancelin, ML. The neuroprotective effect of caffeine: a prospective population study (The Three City Study). Neurology 2007; 69:536-545.

Tsuno N, Jaussent I, Dauvilliers Y, Touchon J, Ritchie K, Besset A. Determinants of excessive daytime sleepiness in a French community-dwelling population.  J Sleep Res 2007; 16:364-371.

Artero S, Ancelin M-L, Portet F, Dupuy ,  Berr C , Dartigues J-F, Tzourio C, Rouaud O, Poncet M, Pasquier F , Auriacombe S, Touchon J, Ritchie K . Risk profiles for Mild Cognitive Impairment and progression to dementia are gender specific. Journal of Neurology, Neurosurgery and Psychiatry 2008; 79:979-984.

Avila-Funes JA, Helmer C, Amieva H, Barberger-Gateau P, Le Goff M, Ritchie K, Portet F, Carrière I, Tavernier B, Gutrtiérez-Robledo LM, Dartigues, JF. Frailty among community-dwelling elderly people in France: the three-city study. J Gerontol A Biol Sci Med Sci 2008; 63:1089-1096

Ben Salem D, Walker PM, Aho S, Tavernier B, Giroud M, Tzourio C, Ricolfi F, Brunotte F. Brain flexibility and balance and gait performances mark morphological and metabolic abnormalities in the elderly. J Clin Neurosci. 2008 Dec;15(12):1360-5. Epub 2008 Oct 26

Ben Salem D, Walker PM, Bejot Y, Aho SL, Tavernier B, Rouaud O, Ricolfi F, Brunotte F. N-acetylaspartate/creatine and choline/creatine ratios in the thalami, insular cortex and white matter as markers of hypertension and cognitive impairment in the elderly. Hypertens Res. 2008;31(10):1851-7

Bruandet A, Richard F, Tzourio C, Berr C, Dartigues Jf, Alperovitch A, Amouyel P, Helbecque N. Haplotypes across ACE and the risk of Alzheimer disease. The Three-City Study. J Alz Disease 2008; 13:333-339.

Chaudieu I*, Beluche I*, Norton J, Boulenger JP, Ritchie K, Ancelin ML. Abnormal reactions to environmental stress in elderly persons with anxiety disorders:evidence from a population study of diurnal cortisol changes.  Journal of Affective Disorders 2008; 106:307-313.

Debette S, Courbon D, Leone N, Gariépy J, Tzourio C, Dartigues JF, Barberger-Gateau P, Ritchie K, Alpérovitch A, Amouyel P, Ducimetière P, Zureik M. Tea consumption is inversely associated with carotid plaques in women. Arterioscl Thromb Vasc Biol 2008; 28:353-359.

Debette S, Leone N, Courbon D, Gariépy J, Tzourio C, Dartigues JF, Ritchie K, Alpérovitch A, Ducimetière P, Amouyel P, Zureik M. Calf circumference is inversely associated with carotid plaques. Stroke 2008; 39:2958-2965

Dupuy AM, Carrière I, Scali J, Cristol JP, Ritchie K, Dartigues JF, Gambert P, Ancelin ML. Lipid levels and cardiovascular risk in elderly women:a general population study of the effects of hormonal treatment and lipid-lowering agents. Climacteric 2008; 11:74-83.

Feart C, Peuchant E, Letenneur L, Samieri C, Montagnier D, Fourrier-Reglat A, Barberger-Gateau P. Plasma eicosapentaenoic acid (EPA) is inversely associated with severity of depressive symptomatology in the elderly: data from the Bordeaux sample of the Three-City study. American Journal of Clinical Nutrition 2008; 87:1156-1162.

Godin O, Dufouil C, Maillard P, Delcroix N, Mazoyer B, Crivello F, Alpérovitch A, Tzourio C. White matter lesions as a predictor of depression in the elderly- The 3C-Dijon study. Biological Psychiatry 2008; 63:663-669.

Helmer C, Pérès K, Pariente A, Pasquier F, Auriacombe S, Poncet M, Portet F, Rouaud O, Ritchie K, Tzourio C, Dartigues JF. Primary and secondary care consultations in elderly demented individuals in France. Results from the Three-City Study. Dement Geriatr Cogn Disord. 2008; 26(5):407-15.

Helmer C, Bricout H, Gin H, Barberger-Gateau P. Macronutrient intake and discrepancy with nutritional recommendations in a group of elderly diabetic subjects. Br J Nutr. 2008; 99:632-638.

Lafont S, Laumon B, Helmer C, Dartigues JF, Fabrigoule C. Driving cessation and self-reported car crashes in older drivers: the impact of cognitive impairment and dementia in a population-based study. J Geriatr Psychiatry Neurology 2008; 21:171-182.

Larrieu S, Carcaillon L, Lefranc A, Helmer C, Dartigues JF, Tavernier B, Ledrans M, Filleul M. Factors associated with morbidity during the 2003 heat wave in two population-based cohort of elderly subjects:PAQUID and the Three-City Study.  Eur J Epidemiol 2008; 23:295-302.

Lenoir H, Lacombe JM, Dufouil C, Ducimetière P, Hanon O, Ritchie K, Dartigues JF, Alpérovitch A, Tzourio C. Relationship between blood pressure and depression in the elderly. The Three-City (3C) Study. J Hypertension 2008; 26:1765-1772.

Leone N , Ducimetière P, Gariépy J, Courbon D, Tzourio C, Dartigues JF, Tzourio C, Alpérovitch A, Amouyel P, Safar ME, Zureik M. Distension of carotid artery and risk of coronary events – The Three-City study. Arterioscl Thromb Vasc Biol 2008; 1392-1397.

Maillard P,  Delcroix N, Crivello F, Dufouil C, Gicquel S, Joliot M, Tzourio-Mazoyer N, Alpérovitch A, Tzourio C,  Mazoyer M. An automated procedure for the assessment of white matter hyperintensities on multispectral (T1, T2, PD) MRI and its between-centre reproducibility evaluation on two large community databases. Neuroradiology 2008; 50:31-42.

Ryan J, Carrière I, Ritchie K, Stewart R, Toulemonde G, Dartigues JF, Tzourio C, Ancelin ML. Late-life depression, gender and mortality:the influence of gender and antidepressant use. British J Psychiatry 2008; 192:10-18.

Ryan J, Carrière I., Scali J. Ritchie K. and Ancelin M.L.  Lifetime hormonal factors may predict late-life depression in women. International Psychogeriatrics 2008; 20:1203-1218.

Samieri C, Féart C, Letenneur L, Dartigues J-F, Pérès K,  Auriacombe S, Peuchant E, Delcourt C, Barberger-Gateau P. Low plasma eicosapentaenoic acid (EPA) and depressive symptomatology are independent predictors of dementia risk. American Journal of Clinical Nutrition 2008; 88: 714-721.

Samieri C, Jutand MA, Féart C,  Capuron L, Letenneur L, Barberger-Gateau P. Dietary patterns derived by hybrid clustering method in older persons: association with cognition, mood and self-rated health. Journal of the American Dietetic Association 2008; 108(9):1461-1471.

Soudry A, Dufouil C, Ritchie K, Dartigues JF, Tzourio C, Alpérovitch A. Factors associated with change in antidepressant use in a community-dwelling elderly cohort. Eur J Clin Pharmacol 2008; 64:51-59.

Soudry A, Dufouil C, Ritchie K, Dartigues JF, Tzourio C, Alpérovitch A. Factors associated with antidepressant use in depressed and non depressed community-dwelling elderly. Int J Geriatr Psychiatry 2008; 23: 324-30.

Stewart R, Dufouil C, Godin O, Ritchie K, Maillard P, Delcroix N, Crivello F, Mazoyer B, Tzourio C. Neuroimaging correlates of subjective memory deficits in a community population. Neurology 2008; 70:1601-1607.

Vidal JS, Dufouil C, Ducros V, Tzourio C. Homocysteine, Folate and Cognition in a Large Community-Based Sample of Elderly People – The 3C Dijon Study. Neuroepidemiology 2008; 30:207-214.

Akbaraly TN, Kivimaki M, Ancelin ML, Barberger-Gateau P, Mura T, Tzourio C, Touchon J, Ritchie K, Berr C. Metabolic syndrome, its components, and mortality in the elderly. J Clin Endocrinol Metab 2010 Nov; 95(11):E327-32. Epub 2010 Sep 1.

Ancelin ML, Carrière I, Boulenger JP, Malafosse A, Stewart R, Cristol JP, Ritchie K, Chaudieu I, Dupuy AM. Gender and genotype modulation of the association between lipid levels and depressive symptomatology in community-dwelling elderly (the ESPRIT study). Biol Psychiatry. 2010 Jul 15;68(2):125-32. Epub 2010 May 26.

Auriacombe S, Helmer C, Amieva H, Berr C, Dubois B, Dartigues JF. Validity of the free and cued selective reminding test in predicting dementia: the 3C study. Neurology 2010; 74:1760-7.

Beluche I, Carrière I, Ritchie K Ancelin ML. A prospective study of diurnal cortisol and cognitive function in community-dwelling elderly people. Psychological Medicine 2010; 40:1039-1049

Bentayeb M, Helmer C, Raherison C, Dartigues JF, Tessier JF, Annesi-Maesano I. Bronchitis-like symptoms and proximity air pollution in French elderly. Respir Med 2010; 104(6): 880-8. Epub 2010 Feb 2.PMID: 20129767

Bonaventure A, Kurth T, Pico F, Barberger-Gateau P, Ritchie K, Stapf C, Tzourio C. Serum triglycerides and the risk of hemorrhagic stroke vs. ischemic vascular events: the Three-City Study. Atherosclerosis 2010; 30:159-167

Crivello F, Lemaître H, Dufouil C, Grassiot B, Delcroix N, Tzourio-Mazoyer N, Tzourio C, Mazoyer B. Effects of ApoE-epsilon4 allele load and age on the rates of grey matter and hippocampal volumes loss in a longitudinal cohort of 1186 healthy elderly persons. Neuroimage 2010; 53(3): 1064-9.

Debette S, Bis JC, Fornage M, Schmidt H, Ikram MA, Sigurdsson S, Heiss G, Struchalin M, Smith AV, van der Lugt A, DeCarli C, Lumley T, Knopman DS, Enzinger C, Eiriksdottir G, Koudstaal PJ, DeStefano AL, Psaty BM, Dufouil C, Catellier DJ, Fazekas F, Aspelund T, Aulchenko YS, Beiser A, Rotter JI, Tzourio C, Shibata DK, Tscherner M, Harris TB, Rivadeneira F, Atwood LD, Rice K, Gottesman RF, van Buchem MA, Uitterlinden AG, Kelly-Hayes M, Cushman M, Zhu Y, Boerwinkle E, Gudnason V, Hofman A, Romero JR, Lopez O, van Duijn CM, Au R, Heckbert SR, Wolf PA, Mosley TH, Seshadri S, Breteler MM, Schmidt R, Launer LJ, Longstreth WT Jr. Genome-wide association studies of MRI-defined brain infarcts: meta-analysis from the CHARGE Consortium. Stroke 2010; 41(2): 210-7

Delcourt C, Korobelnik JF, Barberger-Gateau P, Delfyer MN, Rougier MB, Le Goff  M, Malet F, Colin J, Dartigues JF. Nutrition and age-related eye diseases : the  ALIENOR (antioxydants, lipides essentiels, nutrition et maladies oculaires) study. J Nutr Health Aging 2010 ; 14 :854-61 (the ALIENOR study is conducted in a sub-group of the 3C-Bordeaux cohort.)

Dumurgier J, Elbaz A, Dufouil C, Tavernier B, Tzourio C Hypertension and lower walking speed in the elderly: the Three-City study. J Hypertens 2010; 28(7):1506-14.

Féart C, Siewe A, Samieri C, Peuchant E, Helmer C, Alfos S, Pallet V, Barberger-Gateau P. Plasma retinol and association with socio-demographic and dietary characteristics of free-living older persons: the Bordeaux sample of the three-city study. Int J Vitam Nutr Res 2010; 80:32-44

Féart C, Samieri C, Barberger-Gateau P. Mediterranean diet and cognitive function in older adults. Curr Opin Clin Nutr Metab Care. 2010 Jan;13(1):14-8.

Godin O, Tzourio C, Rouaud O, Zhu Y, Maillard P, Pasquier F, Crivello F, Alpérovitch A, Mazoyer B, Dufouil C. Joint effect of white matter lesions and hippocampal volumes on severity of cognitive decline: the 3C-Dijon MRI study. J Alzheimers Dis 2010; 20(2):453-63.

Lambert JC, Sleegers K, González-Pérez A, Ingelsson M, Beecham GW, Hiltunen M, Combarros O, Bullido MJ, Brouwers N, Bettens K, Berr C, Pasquier F, Richard F, Dekosky ST, Hannequin D, Haines JL, Tognoni G, Fiévet N, Dartigues JF, Tzourio C, Engelborghs S, Arosio B, Coto E, De Deyn P, Del Zompo M, Mateo I, Boada M, Antunez C, Lopez-Arrieta J, Epelbaum J, Schjeide BM, Frank-Garcia A, Giedraitis V, Helisalmi S, Porcellini E, Pilotto A, Forti P, Ferri R, Delepine M, Zelenika D, Lathrop M, Scarpini E, Siciliano G, Solfrizzi V, Sorbi S, Spalletta G, Ravaglia G, Valdivieso F, Vepsäläinen S, Alvarez V, Bosco P, Mancuso M, Panza F, Nacmias B, Bossù P, Hanon O, Piccardi P, Annoni G, Mann D, Marambaud P, Seripa D, Galimberti D, Tanzi RE, Bertram L, Lendon C, Lannfelt L, Licastro F, Campion D, Pericak-Vance MA, Soininen H, Van Broeckhoven C, Alpérovitch A, Ruiz A, Kamboh MI, Amouyel P. The CALHM1 P86L polymorphism is a genetic modifier of age at onset in Alzheimer’s disease: a meta-analysis study. J Alzheimer’s Dis 2010; 22(1): 247-55

Lambert JC, Grenier-Boley B, Chouraki V, Heath S, Zelenika D, Fievet N, Hannequin D, Pasquier F, Hanon O, Brice A, Epelbaum J, Berr C, Dartigues JF, Tzourio C, Campion D, Lathrop M, Amouyel P. Implication of the immune system in Alzheimer’s disease: evidence from genome-wide pathway analysis.  J Alzheimers Dis 2010; 20(4):1107-18

Le Fur I, Laumet G, Richard F, Fiévet N, Berr C, Rouaud O, Delcourt C, Amouyel P, Lambert JC. Association study of the CFH Y402H polymorphism with Alzheimer’s disease. Neurobiol Aging 2010; 31:165-66.

Laumet G, Chouraki V, Grenier-Boley B, Legry V, Heath S, Zelenika D, Fievet N, Hannequin D, Delepine M, Pasquier F, Hanon O, Brice A, Epelbaum J, Berr C, Dartigues JF, Tzourio C, Campion D, Lathrop M, Bertram L, Amouyel P, Lambert JC. Systematic analysis of candidate genes for Alzheimer’s disease in a French, genome-wide association study. J Alzheimers Dis 2010; 20(4): 1181-8

Plichart M, Barberger-Gateau P, Tzourio C, Amouyel P, Pérès K, Ritchie K, Jouven X, Ducimetière P, Empana JP. Disability and incident coronary heart disease in older community-dwelling adults: the Three-City Study. J Am Geriatr Soc2010; 58:636-42

Power T, Stewart R, Ancelin ML, Jaussent I, Malafosse A, Ritchie K. 5-HTTLPR genotype, stressful life events and late-life depression: No evidence of interaction in a French population. Neurobiology of Aging 2010;31:886-887;

Ritchie K, Artero S, Portet F, Brickman AM, Muraskin J, Beanino E, Ancelin ML, Carrière I. Caffeine, cognitive functioning and white matter lesions in the elderly: establishing causality from epidemiological evidence. J Alzheimer’s Disease 2010; 20:S161-S166.

Ritchie K* Carrière I*, Ritchie C, Berr C, Artero S, Ancelin ML. Can we design population prevention programs to reduce dementia incidence? Simulation of the impact of removal of specific risk factors. British Medical Journal 2010, Aug 5;341:c3885. doi: 10.1136/bmj.c3885. & Author replyEpub Sep 3.

Ritchie K, Ancelin ML, Beanino E, Portet., Brickman A, Dartigues JF, Tzourio C, Dupuy AM, Ritchie C, Berr C, Artero S. Retrospective identification and characterization of Mild Cognitive Impairment from a prospective population cohort. Am J Geriatric Psychiatry 2010, 18:692-700.

Scali J, Ryan J, Carrière I, Dartigues JF, Tavernier B, Ritchie K, Ancelin ML. A prospective study of hormone therapy and depression in community-dwelling elderly women: the three city study. J Clin Psychiatry  2010; 71:1673-9

Seshadri S, Fitzpatrick AL, Ikram MA, DeStefano AL, Gudnason V, Boada M, Bis JC, Smith AV, Carassquillo MM, Lambert JC, Harold D, Schrijvers EM, Ramirez-Lorca R, Debette S, Longstreth WT Jr, Janssens AC, Pankratz VS, Dartigues JF, Hollingworth P, Aspelund T, Hernandez I, Beiser A, Kuller LH, Koudstaal PJ, Dickson DW, Tzourio C, Abraham R, Antunez C, Du Y, Rotter JI, Aulchenko YS, Harris TB, Petersen RC, Berr C, Owen MJ, Lopez-Arrieta J, Varadarajan BN, Becker JT, Rivadeneira F, Nalls MA, Graff-Radford NR, Campion D, Auerbach S, Rice K, Hofman A, Jonsson PV, Schmidt H, Lathrop M, Mosley TH, Au R, Psaty BM, Uitterlinden AG, Farrer LA, Lumley T, Ruiz A, Williams J, Amouyel P, Younkin SG, Wolf PA, Launer LJ, Lopez OL, van Duijn CM, Breteler MM; CHARGE Consortium; GERAD1 Consortium; EADI1 Consortium. Genome-wide analysis of genetic loci associated with Alzheimer disease. JAMA 2010; 303(18): 1832-40

Soremekun M, Stewart R, Portet F, Artero S, Ancelin ML, Ritchie K. Neurological signs and late-life depressive symptoms in a community population: the ESPRIT study. Int J Geriatr Psychiatry. 2010 Jul;25(7):672-8.

Straczek C, Ducimetiere P, Barberger-Gateau P, Helmer C, Ritchie K, Jouven X, Carcaillon L, Amouyel P, Tzourio C, Empana JP. Higher level of systemic C-reactive protein is independently predictive of coronary heart disease in older community-dwelling adults: the three-city study. J Am Geriatr Soc 2010 ; 58(1):129-35

Zhu YC, Tzourio C, Soumaré A, Mazoyer B, Dufouil C, Chabriat H. Severity of dilated Virchow-Robin spaces is associated with age, blood pressure, and MRI markers of small vessel disease: a population-based study. Stroke 2010; 41(11): 2483-90.

Zhu YC, Dufouil C, Soumaré A, Mazoyer B, Chabriat H, Tzourio C. High Degree of Dilated Virchow-Robin Spaces on MRI is Associated with Increased Risk of Dementia. J Alzheimer’s Dis 2010 Aug 30. 

Avila-Funes JA, Carcaillon L, Helmer C, Carrière I, Ritchie K, Rouaud O, Tzourio C, Dartigues JF, Amieva H. Is frailty a prodromal stage of vascular dementia? Results from the three-city study. J Am Geriatr Soc. 2012 Sep;60(9):1708-12

Ancelin ML, Carrière I, Barberger-Gateau P, Auriacombe S, Rouaud O, Fourlanos S, Berr C, Dupuy AM, Ritchie K. Lipid lowering agents, cognitive decline, and dementia: the three-city study. J Alzheimers Dis. 2012;30(3):629-37.

Ancelin ML, Carrière I, Helmer C, Rouaud O, Pasquier F, Berr C, Chaudieu I, Ritchie K. Steroid and nonsteroidal anti-inflammatory drugs, cognitive decline, and dementia. Neurobiol Aging. 2012;33(9):2082-90. Epub 2011 Nov 8.

Bazin F, Noize P, Dartigues JF, Ritchie KA, Tavernier B, Moore N, Pariente A, Fourrier-Reglat A. Engagement in leisure activities and benzodiazepine use in a French community-dwelling elderly population. Int J Geriatr Psychiatry. 2012;27(7):716-721. Epub 2011 Aug 31

Bergua V, Meillon C, Potvin O, Bouisson J, Le Goff M, Rouaud O, Ritchie K, Dartigues JF, Amieva H. The STAI-Y trait scale: psychometric properties and normative data from a large population-based study of elderly people. Int Psychogeriatr. 2012 Jul;24(7):1163-71. Epub 2012 Mar 21.

Bis JC, DeCarli C, Smith AV, van der Lijn F, Crivello F, Fornage M, Debette S, Shulman JM, Schmidt H, Srikanth V, Schuur M, Yu L, Choi SH, Sigurdsson S, Verhaaren BF, DeStefano AL, Lambert JC, Jack CR Jr, Struchalin M, Stankovich J, Ibrahim-Verbaas CA, Fleischman D, Zijdenbos A, den Heijer T, Mazoyer B, Coker LH, Enzinger C, Danoy P, Amin N, Arfanakis K, van Buchem MA, de Bruijn RF, Beiser A, Dufouil C, Huang J, Cavalieri M, Thomson R, Niessen WJ, Chibnik LB, Gislason GK, Hofman A, Pikula A, Amouyel P, Freeman KB, Phan TG, Oostra BA, Stein JL, Medland SE, Vasquez AA, Hibar DP, Wright MJ, Franke B, Martin NG, Thompson PM; Enhancing Neuro Imaging Genetics through Meta-Analysis Consortium, Nalls MA, Uitterlinden AG, Au R, Elbaz A, Beare RJ, van Swieten JC, Lopez OL, Harris TB, Chouraki V, Breteler MM, De Jager PL, Becker JT, Vernooij MW, Knopman D, Fazekas F, Wolf PA, van der Lugt A, Gudnason V, Longstreth WT Jr, Brown MA, Bennett DA, van Duijn CM, Mosley TH, Schmidt R, Tzourio C, Launer LJ, Ikram MA, Seshadri S; Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium. Common variants at 12q14 and 12q24 are associated with hippocampal volume.Nat Genet. 2012 Apr 15;44(5):545-51. doi: 10.1038/ng.2237

Blachier M, Dauvilliers Y, Jaussent I, Helmer C, Ritchie K, Jouven X, Tzourio C, Amouyel P, Besset A, Ducimetiere P, Empana JP. Excessive daytime sleepiness and vascular events: the Three City Study. Ann Neurol. 2012 May;71(5):661-7. Epub 2012 Jan 23.

Cacciolati C, Tzourio C, Dufouil C, Alpérovitch A, Hanon O. Feasibility of Home Blood Pressure Measurement in Elderly Individuals: Cross-Sectional Analysis of a Population-Based Sample. Am J Hypertens. 2012 Dec;25(12):1279-85. Epub 2012 Aug 16

Canonico M, Brailly-Tabard S, Gaussem P, Setiao J, Rouaud O, Ryan J, Carcaillon L, Guiochon-Mantel A, Scarabin PY. Endogenous oestradiol as a positive correlate of plasma fibrinogen among older postmenopausal women: a population-based study (the Three-City cohort study). Clin Endocrinol (Oxf). 2012;77(6):905-10

Chasman DI, Fuchsberger C, Pattaro C, Teumer A, Böger CA, Endlich K, Olden M, Chen MH, Tin A, Taliun D, Li M, Gao X, Gorski M, Yang Q, Hundertmark C, Foster MC, O’Seaghdha CM, Glazer N, Isaacs A, Liu CT, Smith AV, O’Connell JR, Struchalin M, Tanaka T, Li G, Johnson AD, Gierman HJ, Feitosa MF, Hwang SJ, Atkinson EJ, Lohman K, Cornelis MC, Johansson A, Tönjes A, Dehghan A, Lambert JC, Holliday EG, Sorice R, Kutalik Z, Lehtimäki T, Esko T, Deshmukh H, Ulivi S, Chu AY, Murgia F, Trompet S, Imboden M, Coassin S, Pistis G; CARDIoGRAM Consortium; ICBP Consortium; CARe Consortium; WTCCC2, Harris TB, Launer LJ, Aspelund T, Eiriksdottir G, Mitchell BD, Boerwinkle E, Schmidt H, Cavalieri M, Rao M, Hu F, Demirkan A, Oostra BA, de Andrade M, Turner ST, Ding J, Andrews JS, Freedman BI, Giulianini F, Koenig W, Illig T, Meisinger C, Gieger C, Zgaga L, Zemunik T, Boban M, Minelli C, Wheeler HE, Igl W, Zaboli G, Wild SH, Wright AF, Campbell H, Ellinghaus D, Nöthlings U, Jacobs G, Biffar R, Ernst F, Homuth G, Kroemer HK, Nauck M, Stracke S, Völker U, Völzke H, Kovacs P, Stumvoll M, Mägi R, Hofman A, Uitterlinden AG, Rivadeneira F, Aulchenko YS, Polasek O, Hastie N, Vitart V, Helmer C, Wang JJ, Stengel B, Ruggiero D, Bergmann S, Kähönen M, Viikari J, Nikopensius T, Province M, Ketkar S, Colhoun H, Doney A, Robino A, Krämer BK, Portas L, Ford I, Buckley BM, Adam M, Thun GA, Paulweber B, Haun M, Sala C, Mitchell P, Ciullo M, Kim SK, Vollenweider P, Raitakari O, Metspalu A, Palmer C, Gasparini P, Pirastu M, Jukema JW, Probst-Hensch NM, Kronenberg F, Toniolo D, Gudnason V, Shuldiner AR, Coresh J, Schmidt R, Ferrucci L, Siscovick DS, van Duijn CM, Borecki IB, Kardia SL, Liu Y, Curhan GC, Rudan I, Gyllensten U, Wilson JF, Franke A, Pramstaller PP, Rettig R, Prokopenko I, Witteman J, Hayward C, Ridker PM, Parsa A, Bochud M, Heid IM, Kao WH, Fox CS, Köttgen A. Integration of genome-wide association studies with biological knowledge identifies six novel genes related to kidney function. Hum Mol Genet. 2012;21(24):5329-43. Epub 2012 Sep 8

Davydov DM, Stewart R, Ritchie K, Chaudieu I. Depressed mood and blood pressure: the moderating effect of situation-specific arousal levels. Int J Psychophysiol. 2012;85(2):212-23. Epub 2012 May 1 (cohorte esprit)

De Hollander EL, Bemelmans WJ, Boshuizen HC, Friedrich N, Wallaschofski H, Guallar-Castillón P, Walter S, Zillikens MC, Rosengren A, Lissner L, Bassett JK, Giles GG, Orsini N, Heim N, Visser M, de Groot LC; WC elderly collaborators. The association between waist circumference and risk of mortality considering body mass index in 65- to 74-year-olds: a meta-analysis of 29 cohorts involving more than 58 000 elderly persons. Int J Epidemiol. 2012 Jun;41(3):805-17. Epub 2012 Mar 31

Delcourt C, Delyfer MN, Rougier MB, Lambert JC, Amouyel P, Colin J, Malet F, Le Goff M, Dartigues JF, Korobelnik JF. ARMS2 A69S polymorphism and the risk for age-related maculopathy: the ALIENOR study. Arch Ophthalmol. 2012 Aug 1;130(8):1077-8

Dumurgier J, Crivello F, Mazoyer B, Ahmed I, Tavernier B, Grabli D, François C, Tzourio-Mazoyer N, Tzourio C, Elbaz A. MRI atrophy of the caudate nucleus and slower walking speed in the elderly. Neuroimage. 2012 Apr 2;60(2):871-8. Epub 2012 Jan 28

Feart C, Alles B, Merle B, Samieri C, Barberger-Gateau P. Adherence to a Mediterranean diet and energy, macro-, and micronutrient intakes in older persons. J Physiol Biochem. 2012;68(4):691-700. Epub 2012 Jul 4

Foubert-Samier A, Catheline G, Amieva H, Dilharreguy B, Helmer C, Allard M, Dartigues JF. Education, occupation, leisure activities, and brain reserve: a population-based study. Neurobiol Aging. 2012 Feb;33(2):423.e15-25.Epub 2010 Nov 12

Germain M, Saut N, Oudot-Mellakh T, Letenneur L, Dupuy AM, Bertrand M, Alessi MC, Lambert JC, Zelenika D, Emmerich J, Tiret L, Cambien F, Lathrop M, Amouyel P, Morange PE, Trégouët DA. Caution in interpreting results from imputation analysis when linkage disequilibrium extends over a large distance: a case study on venous thrombosis. PLoS One. 2012;7(6):e38538. Epub 2012 Jun 4

Glymour MM, Chêne G, Tzourio C, Dufouil C. Brain MRI markers and dropout in a longitudinal study of cognitive aging: The Three-City Dijon Study. Neurology. 2012 Sep 25;79(13):1340-8. Epub 2012 Sep 12.

Glymour MM, Tzourio C, Dufouil C. Is cognitive aging predicted by one’s own or one’s parents’ educational level? results from the three-city study. Am J Epidemiol. 2012 Apr 15;175(8):750-9. Epub 2012 Apr 2.

Godin O, Elbejjani M, Kaufman JS. Body mass index, blood pressure, and risk of depression in the elderly: a marginal structural model. Am J Epidemiol. 2012;176(3):204-13. Epub 2012 Jul 10

Hamilton G, Killick R; Genetic and Environmental Risk for Alzheimer’s Disease Consortium; Translational Genomics Research Institute Consortium, Lambert JC, Amouyel P; European Alzheimer Disease Initiative, Carrasquillo MM, Pankratz VS, Graff-Radford NR, Dickson DW, Petersen RC, Younkin SG, Powell JF, Wade-Martins R. Functional and genetic analysis of haplotypic sequence variation at the nicastrin genomic locus. Neurobiol Aging. 2012 Aug;33(8):1848.e1-13. Epub 2012 Mar 8.

Hong MG, Reynolds CA, Feldman AL, Kallin M, Lambert JC, Amouyel P, Ingelsson E, Pedersen NL, Prince JA. Genome-wide and gene-based association implicates FRMD6 in Alzheimer disease.Hum Mutat. 2012 Mar;33(3):521-9. Epub 2012 Jan 23

Jaussent I, Bouyer J, Ancelin ML, Berr C, Foubert-Samier A, Ritchie K, Ohayon MM, Besset A, Dauvilliers Y. Excessive Sleepiness is Predictive of Cognitive Decline in the Elderly. Sleep. 2012;35(9):1201-7.

Keller MF, Saad M, Bras J, Bettella F, Nicolaou N, Simón-Sánchez J, Mittag F, Büchel F, Sharma M, Gibbs JR, Schulte C, Moskvina V, Durr A, Holmans P, Kilarski LL, Guerreiro R, Hernandez DG, Brice A, Ylikotila P, Stefánsson H, Majamaa K, Morris HR, Williams N, Gasser T, Heutink P, Wood NW, Hardy J, Martinez M, Singleton AB, Nalls MA; International Parkinson’s Disease Genomics Consortium (IPDGC); Wellcome Trust Case Control Consortium 2 (WTCCC2). Using genome-wide complex trait analysis to quantify ‘missing heritability’ in Parkinson’s disease. Hum Mol Genet. 2012 Nov 15;21(22):4996-5009. Epub 2012 Aug 13.

Leone N, Courbon D, Berr C, Barberger-Gateau P, Tzourio C, Alpérovitch A, Zureik M. Abdominal obesity and late-onset asthma: cross-sectional and longitudinal results: the 3C study. Obesity (Silver Spring). 2012 Mar;20(3):628-35. Epub 2011 Oct 20

Manetti M, Allanore Y, Saad M, Fatini C, Cohignac V, Guiducci S, Romano E, Airó P, Caramaschi P, Tinazzi I, Riccieri V, Della Rossa A, Abbate R, Caporali R, Cuomo G, Valesini G, Dieudé P, Hachulla E, Cracowski JL, Tiev K, Letenneur L, Amouyel P, Lambert JC, Chiocchia G, Martinez M, Ibba-Manneschi L, Matucci-Cerinic M. Evidence for caveolin-1 as a new susceptibility gene regulating tissue fibrosis in systemic sclerosis. Ann Rheum Dis. 2012;71(6):1034-41. Epub 2012 Mar 8

Marti H, Carcaillon L, Chavance M. Multiple imputation for estimating hazard ratios and predictive abilities in case-cohort surveys. BMC Med Res Methodol. 2012;12:24. doi: 10.1186/1471-2288-12-24

Mittag F, Büchel F, Saad M, Jahn A, Schulte C, Bochdanovits Z, Simón-Sánchez J, Nalls MA, Keller M, Hernandez DG, Gibbs JR, Lesage S, Brice A, Heutink P, Martinez M, Wood NW, Hardy J, Singleton AB, Zell A, Gasser T, Sharma M; International Parkinson’s Disease Genomics Consortium. Use of support vector machines for disease risk prediction in genome-wide association studies: concerns and opportunities. Hum Mutat. 2012 Dec;33(12):1708-18. Epub 2012 Aug 3.

Noize P, Bazin F, Pariente A, Dufouil C, Ancelin ML, Helmer C, Moore N, Fourrier-Réglat A. Validity of chronic drug exposure presumed from repeated patient interviews varied according to drug class. J Clin Epidemiol. 2012;65(10):1061-8. doi: 10.1016/j.jclinepi.2012.04.009. Epub 2012 Jul 21.

Norton J, Ancelin ML, Stewart R, Berr C, Ritchie K, Carrière I. Anxiety symptoms and disorder predict activity limitations in the elderly. J Affect Disord. 2012 Dec 10;141(2-3):276-85. doi: 10.1016/j.jad.2012.04.002. Epub 2012 May 3.

Pattaro C, Köttgen A, Teumer A, Garnaas M, Böger CA, Fuchsberger C, Olden M, Chen MH, Tin A, Taliun D, Li M, Gao X, Gorski M, Yang Q, Hundertmark C, Foster MC, O’Seaghdha CM, Glazer N, Isaacs A, Liu CT, Smith AV, O’Connell JR, Struchalin M, Tanaka T, Li G, Johnson AD, Gierman HJ, Feitosa M, Hwang SJ, Atkinson EJ, Lohman K, Cornelis MC, Johansson Å, Tönjes A, Dehghan A, Chouraki V, Holliday EG, Sorice R, Kutalik Z, Lehtimäki T, Esko T, Deshmukh H, Ulivi S, Chu AY, Murgia F, Trompet S, Imboden M, Kollerits B, Pistis G; CARDIoGRAM Consortium; ICBP Consortium; CARe Consortium; Wellcome Trust Case Control Consortium 2 (WTCCC2), Harris TB, Launer LJ, Aspelund T, Eiriksdottir G, Mitchell BD, Boerwinkle E, Schmidt H, Cavalieri M, Rao M, Hu FB, Demirkan A, Oostra BA, de Andrade M, Turner ST, Ding J, Andrews JS, Freedman BI, Koenig W, Illig T, Döring A, Wichmann HE, Kolcic I, Zemunik T, Boban M, Minelli C, Wheeler HE, Igl W, Zaboli G, Wild SH, Wright AF, Campbell H, Ellinghaus D, Nöthlings U, Jacobs G, Biffar R, Endlich K, Ernst F, Homuth G, Kroemer HK, Nauck M, Stracke S, Völker U, Völzke H, Kovacs P, Stumvoll M, Mägi R, Hofman A, Uitterlinden AG, Rivadeneira F, Aulchenko YS, Polasek O, Hastie N, Vitart V, Helmer C, Wang JJ, Ruggiero D, Bergmann S, Kähönen M, Viikari J, Nikopensius T, Province M, Ketkar S, Colhoun H, Doney A, Robino A, Giulianini F, Krämer BK, Portas L, Ford I, Buckley BM, Adam M, Thun GA, Paulweber B, Haun M, Sala C, Metzger M, Mitchell P, Ciullo M, Kim SK, Vollenweider P, Raitakari O, Metspalu A, Palmer C, Gasparini P, Pirastu M, Jukema JW, Probst-Hensch NM, Kronenberg F, Toniolo D, Gudnason V, Shuldiner AR, Coresh J, Schmidt R, Ferrucci L, Siscovick DS, van Duijn CM, Borecki I, Kardia SL, Liu Y, Curhan GC, Rudan I, Gyllensten U, Wilson JF, Franke A, Pramstaller PP, Rettig R, Prokopenko I, Witteman JC, Hayward C, Ridker P, Parsa A, Bochud M, Heid IM, Goessling W, Chasman DI, Kao WH, Fox CS. Genome-wide association and functional follow-up reveals new loci for kidney function. PLoS Genet. 2012;8(3):e1002584. Epub 2012 Mar 29

Plichart M, Empana JP, Lambert JC, Amouyel P, Tiret L, Letenneur L, Berr C, Tzourio C, Ducimetière P. Single polymorphism nucleotide rs1333049 on chromosome 9p21 is associated with carotid plaques but not with common carotid intima-media thickness in older adults. A combined analysis of the Three-City and the EVA studies. Atherosclerosis. 2012 May;222(1):187-90. Epub 2012 Mar 3.

Portet F, Brickman AM, Stern Y, Scarmeas N, Muraskin J, Provenzano FA, Berr C, Bonafé A, Artero S, Ritchie K, Akbaraly TN. Metabolic syndrome and localization of white matter hyperintensities in the elderly population. Alzheimers Dement. 2012;8(5 Suppl):S88-95.e1. Epub 2012 Jun 6.

Pottier C, Hannequin D, Coutant S, Rovelet-Lecrux A, Wallon D, Rousseau S, Legallic S, Paquet C, Bombois S, Pariente J, Thomas-Anterion C, Michon A, Croisile B, Etcharry-Bouyx F, Berr C, Dartigues JF, Amouyel P, Dauchel H, Boutoleau-Bretonnière C, Thauvin C, Frebourg T, Lambert JC, Campion D; PHRC GMAJ Collaborators. High frequency of potentially pathogenic SORL1 mutations in autosomal dominant early-onset Alzheimer disease. Mol Psychiatry. 2012 Sep;17(9):875-9. Epub 2012 Apr 3

Rachas A, Raffaitin C, Barberger-Gateau P, Helmer C, Ritchie K, Tzourio C, Amouyel P, Ducimetière P, Empana JP. Clinical usefulness of the metabolic syndrome for the risk of coronary heart disease does not exceed the sum of its individual components in older men and women. The Three-City (3C) Study. Heart. 2012 Apr;98(8):650-5.

Ritchie K, Jaussent I, Portet F, Courtet P, Malafosse A, Maller J, Meslin C, Bonafé A, Le Bars E, de Champfleur NM, Artero S, Ancelin ML. Depression in elderly persons subject to childhood maltreatment is not modulated by corpus callosum and hippocampal loss. J Affect Disord. 2012;141(2-3):294-9. Epub 2012 Apr 24.

Ryan J, Canonico M, Carcaillon L, Carrière I, Scali J, Dartigues JF, Dufouil C, Ritchie K, Scarabin PY, Ancelin ML. Hormone treatment, estrogen receptor polymorphisms and mortality: a prospective cohort study. PLoS One. 2012;7(3):e34112. Epub 2012 Mar 23.

Ryan J, Scali J, Carrière I, Peres K, Rouaud O, Scarabin PY, Ritchie K, Ancelin ML. Estrogen receptor alpha gene variants and major depressive episodes. J Affect Disord. 2012;136(3):1222-6. Epub 2011 Nov 3.

Ryan J, Ancelin ML.Polymorphisms of estrogen receptors and risk of depression: therapeutic implications.Drugs. 2012;72(13):1725-38. doi: 10.2165/11635960-000000000-00000. Review

Samieri C, Maillard P, Crivello F, Proust-Lima C, Peuchant E, Helmer C, Amieva H, Allard M, Dartigues JF, Cunnane SC, Mazoyer BM, Barberger-Gateau P. Plasma long-chain omega-3 fatty acids and atrophy of the medial temporal lobe. Neurology. 2012 Aug 14;79(7):642-50. Epub 2012 Aug 1.

Satizabal CL, Zhu YC, Mazoyer B, Dufouil C, Tzourio C. Circulating IL-6 and CRP are associated with MRI findings in the elderly: the 3C-Dijon Study. Neurology. 2012 Mar 6;78(10):720-7. Epub 2012 Feb 22.

Scarabin-Carré V, Canonico M, Brailly-Tabard S, Trabado S, Ducimetière P, Giroud M, Ryan J, Helmer C, Plu-Bureau G, Guiochon-Mantel A, Scarabin PY. High level of plasma estradiol as a new predictor of ischemic arterial disease in older postmenopausal women: the three-city cohort study. J Am Heart Assoc. 2012;1(3):e001388. Epub 2012 Jun 22.

Sharma M, Ioannidis JP, Aasly JO, Annesi G, Brice A, Van Broeckhoven C, Bertram L, Bozi M, Crosiers D, Clarke C, Facheris M, Farrer M, Garraux G, Gispert S, Auburger G, Vilariño-Güell C, Hadjigeorgiou GM, Hicks AA, Hattori N, Jeon B, Lesage S, Lill CM, Lin JJ, Lynch T, Lichtner P, Lang AE, Mok V, Jasinska-Myga B, Mellick GD, Morrison KE, Opala G, Pramstaller PP, Pichler I, Park SS, Quattrone A, Rogaeva E, Ross OA, Stefanis L, Stockton JD, Satake W, Silburn PA, Theuns J, Tan EK, Toda T, Tomiyama H, Uitti RJ, Wirdefeldt K, Wszolek Z, Xiromerisiou G, Yueh KC, Zhao Y, Gasser T, Maraganore D, Krüger R; GEO-PD Consortium. Large-scale replication and heterogeneity in Parkinson disease genetic loci. Neurology. 2012 Aug 14;79(7):659-67. Epub 2012 Jul 11.

Soisson V, Brailly-Tabard S, Empana JP, Féart C, Ryan J, Bertrand M, Guiochon-Mantel A, Scarabin PY. Low plasma testosterone and elevated carotid intima-media thickness: importance of low-grade inflammation in elderly men. Atherosclerosis. 2012;223(1):244-9. Epub 2012 May 16

Stein JL, Medland SE, Vasquez AA, Hibar DP, Senstad RE, Winkler AM, Toro R, Appel K, Bartecek R, Bergmann Ø, Bernard M, Brown AA, Cannon DM, Chakravarty MM, Christoforou A, Domin M, Grimm O, Hollinshead M, Holmes AJ, Homuth G, Hottenga JJ, Langan C, Lopez LM, Hansell NK, Hwang KS, Kim S, Laje G, Lee PH, Liu X, Loth E, Lourdusamy A, Mattingsdal M, Mohnke S, Maniega SM, Nho K, Nugent AC, O’Brien C, Papmeyer M, Pütz B, Ramasamy A, Rasmussen J, Rijpkema M, Risacher SL, Roddey JC, Rose EJ, Ryten M, Shen L, Sprooten E, Strengman E, Teumer A, Trabzuni D, Turner J, van Eijk K, van Erp TG, van Tol MJ, Wittfeld K, Wolf C, Woudstra S, Aleman A, Alhusaini S, Almasy L, Binder EB, Brohawn DG, Cantor RM, Carless MA, Corvin A, Czisch M, Curran JE, Davies G, de Almeida MA, Delanty N, Depondt C, Duggirala R, Dyer TD, Erk S, Fagerness J, Fox PT, Freimer NB, Gill M, Göring HH, Hagler DJ, Hoehn D, Holsboer F, Hoogman M, Hosten N, Jahanshad N, Johnson MP, Kasperaviciute D, Kent JW Jr, Kochunov P, Lancaster JL, Lawrie SM, Liewald DC, Mandl R, Matarin M, Mattheisen M, Meisenzahl E, Melle I, Moses EK, Mühleisen TW, Nauck M, Nöthen MM, Olvera RL, Pandolfo M, Pike GB, Puls R, Reinvang I, Rentería ME, Rietschel M, Roffman JL, Royle NA, Rujescu D, Savitz J, Schnack HG, Schnell K, Seiferth N, Smith C, Steen VM, Valdés Hernández MC, Van den Heuvel M, van der Wee NJ, Van Haren NE, Veltman JA, Völzke H, Walker R, Westlye LT, Whelan CD, Agartz I, Boomsma DI, Cavalleri GL, Dale AM, Djurovic S, Drevets WC, Hagoort P, Hall J, Heinz A, Jack CR Jr, Foroud TM, Le Hellard S, Macciardi F, Montgomery GW, Poline JB, Porteous DJ, Sisodiya SM, Starr JM, Sussmann J, Toga AW, Veltman DJ, Walter H, Weiner MW; Alzheimer’s Disease Neuroimaging Initiative; EPIGEN Consortium; IMAGEN Consortium; Saguenay Youth Study Group, Bis JC, Ikram MA, Smith AV, Gudnason V, Tzourio C, Vernooij MW, Launer LJ, DeCarli C, Seshadri S; Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium, Andreassen OA, Apostolova LG, Bastin ME, Blangero J, Brunner HG, Buckner RL, Cichon S, Coppola G, de Zubicaray GI, Deary IJ, Donohoe G, de Geus EJ, Espeseth T, Fernández G, Glahn DC, Grabe HJ, Hardy J, Hulshoff Pol HE, Jenkinson M, Kahn RS, McDonald C, McIntosh AM, McMahon FJ, McMahon KL, Meyer-Lindenberg A, Morris DW, Müller-Myhsok B, Nichols TE, Ophoff RA, Paus T, Pausova Z, Penninx BW, Potkin SG, Sämann PG, Saykin AJ, Schumann G, Smoller JW, Wardlaw JM, Weale ME, Martin NG, Franke B, Wright MJ, Thompson PM; Enhancing Neuro Imaging Genetics through Meta-Analysis Consortium. Identification of common variants associated with human hippocampal and intracranial volumes. Nat Genet. 2012 Apr 15;44(5):552-61. doi: 10.1038/ng.2250.

Tregouet DA, Sabater-Lleal M, Bruzelius M, Emmerich J, Amouyel P, Dartigues JF, Kieler H, Morange PE. Lack of association of non-synonymous FUT2 and ALPL polymorphisms with venous thrombosis. J Thromb Haemost. 2012 Aug;10(8):1693-5.

Zhu YC, Chabriat H, Godin O, Dufouil C, Rosand J, Greenberg SM, Smith EE, Tzourio C, Viswanathan A. Distribution of white matter hyperintensity in cerebral hemorrhage and healthy aging. J Neurol. 2012;259(3):530-6

Ancelin ML, Ripoche E, Dupuy AM, Barberger-Gateau P, Auriacombe S, Rouaud O, Berr C, Carrière I, Ritchie K. Sex differences in the associations between lipid levels and incident dementia. J Alzheimers Dis. 2013 Jan 1;34(2):519-28. doi: 10.3233/JAD-121228

Ancelin ML, Carrière I, Scali J, Ritchie K, Chaudieu I, Ryan J. Angiotensin-converting enzyme gene variants are associated with both cortisol secretion and late-life depression. Transl Psy chiatry. 2013 Nov 5;3:e322. doi: 10.1038/tp.2013.95

Artaud F, Dugravot A, Sabia S, Singh-Manoux A, Tzourio C, Elbaz A. Unhealthy behaviours and disability in older adults: the Three-City Dijon cohort study. BMJ 2013;347:f4240. doi: 10.1136/bmj.f4240

Barberger-Gateau P, Lambert JC, Féart C, Pérès K, Ritchie K, Dartigues JF, Alpérovitch A. From genetics to dietetics: the contribution of epidemiology to understanding Alzheimer’s disease. J Alzheimers Dis. 2013;33 Suppl 1:S457-63

Brisset M, Boutouyrie P, Pico F, Zhu Y, Zureik M, Schilling S, Dufouil C, Mazoyer B, Laurent S, Tzourio C, Debette S. Large-vessel correlates of cerebral small-vessel disease. Neurology. 2013 Feb 12;80(7):662-669. Epub 2013 Jan 23.

Cacciolati C, Tzourio C, Hanon O. Blood pressure variability in elderly persons with white-coat and masked hypertension compared to those with normotension and sustained hypertension. Am J Hypertens. 2013 Mar;26(3):367-72. Epub 2012 Dec 21

Cacciolati C, Hanon O, Dufouil C, Alpérovitch A, Tzourio C. Categories of hypertension in the elderly and their 1-year evolution. The Three-City Study. J Hypertens. 2013 Apr;31(4):680-9. doi: 10.1097/HJH.0b013e32835ee0ca

Carrière I, Delcourt C, Daien V, Pérès K, Féart C, Berr C, Laure Ancelin M, Ritchie K. A prospective study of the bi-directional association between vision loss and depression in the elderly. J Affect Disord. 2013;151(1):164-70. Epub 2013 Jun 1

Carrière I, Ryan J, Norton J, Scali J, Stewart R, Ritchie K, Ancelin ML. Anxiety and mortality risk in community-dwelling elderly people. Br J Psychiatry. 2013;203(3):303-9. Epub 2013 Aug 8

Chapuis J, Hansmannel F, Gistelinck M, Mounier A, Van Cauwenberghe C, Kolen KV, Geller F, Sottejeau Y, Harold D, Dourlen P, Grenier-Boley B, Kamatani Y, Delepine B, Demiautte F, Zelenika D, Zommer N, Hamdane M, Bellenguez C, Dartigues JF, Hauw JJ, Letronne F, Ayral AM, Sleegers K, Schellens A, Broeck LV, Engelborghs S, De Deyn PP, Vandenberghe R, O’Donovan M, Owen M, Epelbaum J, Mercken M, Karran E, Bantscheff M, Drewes G, Joberty G, Campion D, Octave JN, Berr C, Lathrop M, Callaerts P, Mann D, Williams J, Buée L, Dewachter I, Van Broeckhoven C, Amouyel P, Moechars D, Dermaut B, Lambert JC. Increased expression of BIN1 mediates Alzheimer genetic risk by modulating tau pathology. Mol Psychiatry. 2013;18(11):1225-34

Cheng CY, Schache M, Ikram MK, Young TL, Guggenheim JA, Vitart V, Macgregor S, Verhoeven VJ, Barathi VA, Liao J, Hysi PG, Bailey-Wilson JE, St Pourcain B, Kemp JP, McMahon G, Timpson NJ, Evans DM, Montgomery GW, Mishra A, Wang YX, Wang JJ, Rochtchina E, Polasek O, Wright AF, Amin N, van Leeuwen EM, Wilson JF, Pennell CE, van Duijn CM, de Jong PT, Vingerling JR, Zhou X, Chen P, Li R, Tay WT, Zheng Y, Chew M; Consortium for Refractive Error and Myopia, Burdon KP, Craig JE, Iyengar SK, Igo RP Jr, Lass JH Jr; The Fuchs’ Genetics Multi-Center Study Group, Chew EY, Haller T, Mihailov E, Metspalu A, Wedenoja J, Simpson CL, Wojciechowski R, Höhn R, Mirshahi A, Zeller T, Pfeiffer N, Lackner KJ; Wellcome Trust Case Control Consortium 2, Bettecken T, Meitinger T, Oexle K, Pirastu M, Portas L, Nag A, Williams KM, Yonova-Doing E, Klein R, Klein BE, Hosseini SM, Paterson AD; Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions, and Complications Research Group, Makela KM, Lehtimaki T, Kahonen M, Raitakari O, Yoshimura N, Matsuda F, Chen LJ, Pang CP, Yip SP, Yap MK, Meguro A, Mizuki N, Inoko H, Foster PJ, Zhao JH, Vithana E, Tai ES, Fan Q, Xu L, Campbell H, Fleck B, Rudan I, Aung T, Hofman A, Uitterlinden AG, Bencic G, Khor CC, Forward H, Pärssinen O, Mitchell P, Rivadeneira F, Hewitt AW, Williams C, Oostra BA, Teo YY, Hammond CJ, Stambolian D, Mackey DA, Klaver CC, Wong TY, Saw SM, Baird PN. Nine Loci for Ocular Axial Length Identified through Genome-wide Association Studies, Including Shared Loci with Refractive Error. Am J Hum Genet. 2013;93(2):264-77

Cougnard-Grégoire A, Delyfer MN, Korobelnik JF, Rougier MB, Malet F, Le Goff M, Dartigues JF, Colin J, Barberger-Gateau P, Delcourt C. Long-Term Blood Pressure and Age-Related Macular Degeneration: The ALIENOR Study. Invest Ophthalmol Vis Sci. 2013;54(3):1905-12.

Culverhouse RC, Bowes L, Breslau N, Nurnberger JI Jr, Burmeister M, Fergusson DM, Munafò M, Saccone NL, Bierut LJ; 5-HTTLPR, Stress, and Depression Consortium. Protocol for a collaborative meta-analysis of 5-HTTLPR, stress, and depression. BMC Psychiatry. 2013 Nov 12;13:304. doi: 10.1186/1471-244X-13-304

Danaei G, Singh GM, Paciorek CJ, Lin JK, Cowan MJ, Finucane MM, Farzadfar F, Stevens GA, Riley LM, Lu Y, Rao M, Ezzati M; Global Burden of Metabolic Risk Factors of Chronic Diseases Collaborating Group. The global cardiovascular risk transition: associations of four metabolic risk factors with national income, urbanization, and Western diet in 1980 and 2008. Circulation. 2013;127(14):1493-502, 1502e1-8. doi: 10.1161/CIRCULATIONAHA.113.001470. Epub 2013 Mar 12

Dartigues JF, Foubert-Samier A, Helmer C. Relationship between educational level and dementia: Social factor and age-related chronic disease. Rev Epidemiol Sante Publique. 2013;61 Suppl 3:S195-8. Epub 2013 Jul 5. French

Delva F, Pimouguet C, Helmer C, Péres K, Bréchat B, Le Goff M, Jacqmin-Gadda H, Amieva H, Orgogozo JM, Auriacombe S, Berr C, Tzourio C, Barberger-Gateau P, Dartigues JF. A Simple Score to Predict Survival with Dementia in the General Population. Neuroepidemiology. 2013;41(1):20-28. Epub 2013 Mar 19

Elbaz A, Vicente-Vytopilova P, Tavernier B, Sabia S, Dumurgier J, Mazoyer B, Singh-Manoux A, Tzourio C. Motor function in the elderly: evidence for the reserve hypothesis. Neurology 2013;81:417-426. Epub 2013 Jun 26

Engberink AO, Pimouguet C, Amouyal M, Gerassimo O, Bourrel G, Berr C. Determinants of support for dementia patients in general practice: a qualitative approach based on an epidemiological cohort. Geriatr Psychol Neuropsychiatr Vieil. 2013;11(2):157-167

Feart C, Lorrain S, Ginder Coupez V, Samieri C, Letenneur L, Paineau D, Barberger-Gateau P. Adherence to a Mediterranean diet and risk of fractures in French older persons. Osteoporos Int. 2013;24(12):3031-41. Epub 2013 Jun 20

Féart C, Samieri C, Allès B, Barberger-Gateau P. Potential benefits of adherence to the Mediterranean diet on cognitive health. Proc Nutr Soc. 2013;72(1):140-52. Epub 2012 Dec 11

Gabelle A, Richard F, Gutierrez LA, Schraen S, Delva F, Rouaud O, Buée L, Dartigues JF, Touchon J, Lambert JC, Berr C. Plasma amyloid-β levels and prognosis in incident dementia cases of the 3-City Study. J Alzheimers Dis. 2013;33(2):381-91

Genziani M, Stewart R, Béjot Y, Amieva H, Artero S, Ritchie K. Subjective memory impairment, objective cognitive functioning and social activity in French older people: findings from the Three Cities study. Geriatr Gerontol Int. 2013 Jan;13(1):139-45. Epub 2012 Jun 7

Germain M, Eyries M, Montani D, Poirier O, Girerd B, Dorfmüller P, Coulet F, Nadaud S, Maugenre S, Guignabert C, Carpentier W, Vonk-Noordegraaf A, Lévy M, Chaouat A, Lambert JC, Bertrand M, Dupuy AM, Letenneur L, Lathrop M, Amouyel P, de Ravel TJ, Delcroix M, Austin ED, Robbins IM, Hemnes AR, Loyd JE, Berman-Rosenzweig E, Barst RJ, Chung WK, Simonneau G, Trégouët DA, Humbert M, Soubrier F. Genome-wide association analysis identifies a susceptibility locus for pulmonary arterial hypertension. Nat Genet. 2013;45(5):518-21. Epub 2013 Mar 17

Guerreiro R, Wojtas A, Bras J, Carrasquillo M, Rogaeva E, Majounie E, Cruchaga C, Sassi C, Kauwe JS, Younkin S, Hazrati L, Collinge J, Pocock J, Lashley T, Williams J, Lambert JC, Amouyel P, Goate A, Rademakers R, Morgan K, Powell J, St George-Hyslop P, Singleton A, Hardy J; Alzheimer Genetic Analysis Group. TREM2 variants in Alzheimer’s disease. N Engl J Med. 2013 Jan 10;368(2):117-27. Epub 2012 Nov 14

Greliche N, Germain M, Lambert JC, Cohen W, Bertrand M, Dupuis AM, Letenneur L, Lathrop M, Amouyel P, Morange PE, Trégouët DA. A genome-wide search for common SNP x SNP interactions on the risk of venous thrombosis. BMC Med Genet. 2013;14:36. doi: 10.1186/1471-2350-14-36

Grimaud O, Lapostolle A, Berr C, Helmer C, Dufouil C, Kihal W, Alpérovitch A, Chauvin P. Gender differences in the association between socioeconomic status and subclinical atherosclerosis. PLoS One. 2013;8(11):e80195

Helmer C, Malet F, Rougier MB, Schweitzer C, Colin J, Delyfer MN, Korobelnik JF, Barberger-Gateau P, Dartigues JF, Delcourt C. Is there a link between open-angle glaucoma and dementia? The 3C-alienor cohort. Ann Neurol. 2013;74(2):171-9

Holmans P, Moskvina V, Jones L, Sharma M; International Parkinson’s Disease Genomics Consortium, Vedernikov A, Buchel F, Sadd M, Bras JM, Bettella F, Nicolaou N, Simón-Sánchez J, Mittag F, Gibbs JR, Schulte C, Durr A, Guerreiro R, Hernandez D, Brice A, Stefánsson H, Majamaa K, Gasser T, Heutink P, Wood NW, Martinez M, Singleton AB, Nalls MA, Hardy J, Morris HR, Williams NM. A pathway-based analysis provides additional support for an immune-related genetic susceptibility to Parkinson’s disease. Hum Mol Genet. 2013 Mar 1;22(5):1039-49. Epub 2012 Dec 7

Jaussent I, Empana JP, Ancelin ML, Besset A, Helmer C, Tzourio C, Ritchie K, Bouyer J, Dauvilliers Y. Insomnia, daytime sleepiness and cardio-cerebrovascular diseases in the elderly: a 6-year prospective study. PLoS One. 2013;8(2):e56048. Epub 2013 Feb 14

Jaussent I, Ancelin ML, Berr C, Pérès K, Scali J, Besset A, Ritchie K, Dauvilliers Y. Hypnotics and mortality in an elderly general population: a 12-year prospective study. BMC Med. 2013;11(1):212

Klebe S, Golmard JL, Nalls MA, Saad M, Singleton AB, Bras JM, Hardy J, Simon-Sanchez J, Heutink P, Kuhlenbäumer G, Charfi R, Klein C, Hagenah J, Gasser T, Wurster I, Lesage S, Lorenz D, Deuschl G, Durif F, Pollak P, Damier P, Tison F, Durr A, Amouyel P, Lambert JC, Tzourio C, Maubaret C, Charbonnier-Beaupel F, Tahiri K, Vidailhet M, Martinez M, Brice A, Corvol JC; French Parkinson’s Disease Genetics Study Group and the International Parkinson’s Disease Genomics Consortium (IPDGC). The Val158Met COMT polymorphism is a modifier of the age at onset in Parkinson’s disease with a sexual dimorphism. J Neurol Neurosurg Psychiatry. 2013;84(6):666-73. doi: 10.1136/jnnp-2012-304475. Epub 2013 Feb 13

Koumakis E, Bouaziz M, Dieudé P, Ruiz B, Riemekasten G, Airo P, Müller-Nurasyid M, Cusi D, Matucci-Cerinic M, Melchers I, Salvi E, Strauch K, Peters A, Cuomo G, Hachulla E, Diot E, Hunzelmann N, Caramaschi P, Riccieri V, Distler JH, Tarner I, Avouac J, Letenneur L, Amouyel P, Lambert JC, Chiocchia G, Boileau C, Allanore Y. A regulatory variant in CCR6 is associated with anti-topoisomerase positive systemic sclerosis susceptibility. Arthritis Rheum. 2013;65(12):3202-8

Lambert JC, Grenier-Boley B, Harold D, Zelenika D, Chouraki V, Kamatani Y, Sleegers K, Ikram MA, Hiltunen M, Reitz C, Mateo I, Feulner T, Bullido M, Galimberti D, Concari L, Alvarez V, Sims R, Gerrish A, Chapman J, Deniz-Naranjo C, Solfrizzi V, Sorbi S, Arosio B, Spalletta G, Siciliano G, Epelbaum J, Hannequin D, Dartigues JF, Tzourio C, Berr C, Schrijvers EM, Rogers R, Tosto G, Pasquier F, Bettens K, Van Cauwenberghe C, Fratiglioni L, Graff C, Delepine M, Ferri R, Reynolds CA, Lannfelt L, Ingelsson M, Prince JA, Chillotti C, Pilotto A, Seripa D, Boland A, Mancuso M, Bossù P, Annoni G, Nacmias B, Bosco P, Panza F, Sanchez-Garcia F, Del Zompo M, Coto E, Owen M, O’Donovan M, Valdivieso F, Caffarra P, Scarpini E, Combarros O, Buée L, Campion D, Soininen H, Breteler M, Riemenschneider M, Van Broeckhoven C, Alpérovitch A, Lathrop M, Trégouët DA, Williams J, Amouyel P. Genome-wide haplotype association study identifies the FRMD4A gene as a risk locus for Alzheimer’s disease. Mol Psychiatry. 2013 Apr;18(4):461-70. doi: 10.1038/mp.2012.14. Epub 2012 Mar 20.

Lambert JC, Ibrahim-Verbaas CA, Harold D, Naj AC, Sims R, Bellenguez C, Jun G, Destefano AL, Bis JC, Beecham GW, Grenier-Boley B, Russo G, Thornton-Wells TA, Jones N, Smith AV, Chouraki V, Thomas C, Ikram MA, Zelenika D, Vardarajan BN, Kamatani Y, Lin CF, Gerrish A, Schmidt H, Kunkle B, Dunstan ML, Ruiz A, Bihoreau MT, Choi SH, Reitz C, Pasquier F, Hollingworth P, Ramirez A, Hanon O, Fitzpatrick AL, Buxbaum JD, Campion D, Crane PK, Baldwin C, Becker T, Gudnason V, Cruchaga C, Craig D, Amin N, Berr C, Lopez OL, De Jager PL, Deramecourt V, Johnston JA, Evans D, Lovestone S, Letenneur L, Morón FJ, Rubinsztein DC, Eiriksdottir G, Sleegers K, Goate AM, Fiévet N, Huentelman MJ, Gill M, Brown K, Kamboh MI, Keller L, Barberger-Gateau P, McGuinness B, Larson EB, Green R, Myers AJ, Dufouil C, Todd S, Wallon D, Love S, Rogaeva E, Gallacher J, St George-Hyslop P, Clarimon J, Lleo A, Bayer A, Tsuang DW, Yu L, Tsolaki M, Bossù P, Spalletta G, Proitsi P, Collinge J, Sorbi S, Sanchez-Garcia F, Fox NC, Hardy J, Naranjo MC, Bosco P, Clarke R, Brayne C, Galimberti D, Mancuso M, Matthews F; European Alzheimer’s Disease Initiative (EADI); Genetic and Environmental Risk in Alzheimer’s Disease (GERAD); Alzheimer’s Disease Genetic Consortium (ADGC); Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE), Moebus S, Mecocci P, Del Zompo M, Maier W, Hampel H, Pilotto A, Bullido M, Panza F, Caffarra P, Nacmias B, Gilbert JR, Mayhaus M, Lannfelt L, Hakonarson H, Pichler S, Carrasquillo MM, Ingelsson M, Beekly D, Alvarez V, Zou F, Valladares O, Younkin SG, Coto E, Hamilton-Nelson KL, Gu W, Razquin C, Pastor P, Mateo I, Owen MJ, Faber KM, Jonsson PV, Combarros O, O’Donovan MC, Cantwell LB, Soininen H, Blacker D, Mead S, Mosley TH Jr, Bennett DA, Harris TB, Fratiglioni L, Holmes C, de Bruijn RF, Passmore P, Montine TJ, Bettens K, Rotter JI, Brice A, Morgan K, Foroud TM, Kukull WA, Hannequin D, Powell JF, Nalls MA, Ritchie K, Lunetta KL, Kauwe JS, Boerwinkle E, Riemenschneider M, Boada M, Hiltunen M, Martin ER, Schmidt R, Rujescu D, Wang LS, Dartigues JF, Mayeux R, Tzourio C, Hofman A, Nöthen MM, Graff C, Psaty BM, Jones L, Haines JL, Holmans PA, Lathrop M, Pericak-Vance MA, Launer LJ, Farrer LA, van Duijn CM, Van Broeckhoven C, Moskvina V, Seshadri S, Williams J, Schellenberg GD, Amouyel P. Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer’s disease. Nat Genet. 2013 Dec;45(12):1452-8

Merle BM, Delyfer MN, Korobelnik JF, Rougier MB, Malet F, Féart C, Le Goff M, Peuchant E, Letenneur L, Dartigues JF, Colin J, Barberger-Gateau P, Delcourt C. High Concentrations of Plasma n3 Fatty Acids Are Associated with Decreased Risk for Late Age-Related Macular Degeneration. J Nutr. 2013 Apr;143(4):505-11. Epub 2013 Feb 13.

Merle BM, Maubaret C, Korobelnik JF, Delyfer MN, Rougier MB, Lambert JC, Amouyel P, Malet F, Le Goff M, Dartigues JF, Barberger-Gateau P, Delcourt C. Association of HDL-Related Loci with Age-Related Macular Degeneration and Plasma Lutein and Zeaxanthin: the Alienor Study. PLoS One. 2013;8(11):e79848

Mortamais M, Reynes C, Brickman AM, Provenzano FA, Muraskin J, Portet F, Berr C, Touchon J, Bonafé A, le Bars E, Maller JJ, Meslin C, Sabatier R, Ritchie K, Artero S. Spatial distribution of cerebral white matter lesions predicts progression to mild cognitive impairment and dementia. PLoS One. 2013;8(2):e56972. Epub 2013 Feb 14. (cohorte esprit)

Mortamais M, Artero S, Ritchie K. Cerebral white matter hyperintensities in the prediction of cognitive decline and incident dementia. Int Rev Psychiatry. 2013;25(6):686-98

Mura T, Proust-Lima C, Akbaraly T, Amieva H, Tzourio C, Chevassus H, Picot MC, Jacqumin-Gadda H, Berr C. Chronic use of benzodiazepines and latent cognitive decline in the elderly: Results from the Three-city study. Eur Neuropsychopharmacol. 2013 Mar;23(3):212-23. Epub 2012 Jun 15

Psaltopoulou T, Sergentanis TN, Panagiotakos DB, Sergentanis IN, Kosti R, Scarmeas N. Mediterranean diet, stroke, cognitive impairment, and depression: A meta-analysis. Ann Neurol. 2013;74(4):580-91. Epub 2013 Sep 16

Parsa A, Fuchsberger C, Köttgen A, O’Seaghdha CM, Pattaro C, de Andrade M, Chasman DI, Teumer A, Endlich K, Olden M, Chen MH, Tin A, Kim YJ, Taliun D, Li M, Feitosa M, Gorski M, Yang Q, Hundertmark C, Foster MC, Glazer N, Isaacs A, Rao M, Smith AV, O’Connell JR, Struchalin M, Tanaka T, Li G, Hwang SJ, Atkinson EJ, Lohman K, Cornelis MC, Johansson A, Tönjes A, Dehghan A, Couraki V, Holliday EG, Sorice R, Kutalik Z, Lehtimäki T, Esko T, Deshmukh H, Ulivi S, Chu AY, Murgia F, Trompet S, Imboden M, Kollerits B, Pistis G, Harris TB, Launer LJ, Aspelund T, Eiriksdottir G, Mitchell BD, Boerwinkle E, Schmidt H, Hofer E, Hu F, Demirkan A, Oostra BA, Turner ST, Ding J, Andrews JS, Freedman BI, Giulianini F, Koenig W, Illig T, Döring A, Wichmann HE, Zgaga L, Zemunik T, Boban M, Minelli C, Wheeler HE, Igl W, Zaboli G, Wild SH, Wright AF, Campbell H, Ellinghaus D, Nöthlings U, Jacobs G, Biffar R, Ernst F, Homuth G, Kroemer HK, Nauck M, Stracke S, Völker U, Völzke H, Kovacs P, Stumvoll M, Mägi R, Hofman A, Uitterlinden AG, Rivadeneira F, Aulchenko YS, Polasek O, Hastie N, Vitart V, Helmer C, Wang JJ, Stengel B, Ruggiero D, Bergmann S, Kähönen M, Viikari J, Nikopensius T, Province M, Colhoun H, Doney A, Robino A, Krämer BK, Portas L, Ford I, Buckley BM, Adam M, Thun GA, Paulweber B, Haun M, Sala C, Mitchell P, Ciullo M, Vollenweider P, Raitakari O, Metspalu A, Palmer C, Gasparini P, Pirastu M, Jukema JW, Probst-Hensch NM, Kronenberg F, Toniolo D, Gudnason V, Shuldiner AR, Coresh J, Schmidt R, Ferrucci L, van Duijn CM, Borecki I, Kardia SL, Liu Y, Curhan GC, Rudan I, Gyllensten U, Wilson JF, Franke A, Pramstaller PP, Rettig R, Prokopenko I, Witteman J, Hayward C, Ridker PM, Bochud M, Heid IM, Siscovick DS, Fox CS, Kao WL, Böger CA. Common Variants in Mendelian Kidney Disease Genes and Their Association with Renal Function. J Am Soc Nephrol.;24(12):2105-17. Epub 2013 Sep 12

Péquignot R, Tzourio C, Péres K, Ancellin ML, Perier MC, Ducimetière P, Empana JP. Depressive symptoms, antidepressants and disability and future coronary heart disease and stroke events in older adults: the Three City Study. Eur J Epidemiol. 2013 Mar;28(3):249-56. Epub 2013 Jan 22.

Pichler I, Del Greco M F, Gögele M, Lill CM, Bertram L, Do CB, Eriksson N, Foroud T, Myers RH; PD GWAS Consortium, Nalls M, Keller MF; International Parkinson’s Disease Genomics Consortium; Wellcome Trust Case Control Consortium 2, Benyamin B, Whitfield JB; Genetics of Iron Status Consortium, Pramstaller PP, Hicks AA, Thompson JR, Minelli C. Serum iron levels and the risk of Parkinson disease: a mendelian randomization study. PLoS Med. 2013;10(6):e1001462. doi: 10.1371/journal.pmed.1001462. Epub 2013 Jun 4. Erratum in: PLoS Med. 2013 Jun;10(6). doi:10.1371/annotation/c4d81646-0c0e-4a3e-9425-b220bae2d8b6

Potvin O, Bergua V, Swendsen J, Meillon C, Tzourio C, Ritchie K, Dartigues JF, Amieva H. Anxiety and 10-year risk of incident and recurrent depressive symptomatology in older adults. Depress Anxiety. 2013;30(6):554-63. doi: 10.1002/da.22101. Epub 2013 Mar 26

Ritchie K, Norton J, Mann A, Carrière I, Ancelin ML. Late-Onset Agoraphobia: General Population Incidence and Evidence for a Clinical Subtype. Am J Psychiatry. 2013;170(7):790-798

Rodríguez-Mañas L, Féart C, Mann G, Viña J, Chatterji S, Chodzko-Zajko W, Gonzalez-Colaço Harmand M, Bergman H, Carcaillon L, Nicholson C, Scuteri A, Sinclair A, Pelaez M, Van der Cammen T, Beland F, Bickenbach J, Delamarche P, Ferrucci L, Fried LP, Gutiérrez-Robledo LM, Rockwood K, Rodríguez Artalejo F, Serviddio G, Vega E; FOD-CC group (Appendix 1). Searching for an operational definition of frailty: a Delphi method based consensus statement: the frailty operative definition-consensus conference project. J Gerontol A Biol Sci Med Sci. 2013;68(1):62-7. Epub 2012 Apr 16

Ryan J, Carrière I, Carcaillon L, Dartigues JF, Auriacombe S, Rouaud O, Berr C, Ritchie K, Scarabin PY, Ancelin ML. Estrogen receptor polymorphisms and incident dementia: The prospective 3C study. Alzheimers Dement. 2013 Mar 9. doi:pii: S1552-5260(13)00011-3. 10.1016/j.jalz.2012.12.008. [Epub ahead of print]

Sachdev PS, Lipnicki DM, Kochan NA, Crawford JD, Rockwood K, Xiao S, Li J, Li X, Brayne C, Matthews FE, Stephan BC, Lipton RB, Katz MJ, Ritchie K, Carrière I, Ancelin ML, Seshadri S, Au R, Beiser AS, Lam LC, Wong CH, Fung AW, Kim KW, Han JW, Kim TH, Petersen RC, Roberts RO, Mielke MM, Ganguli M, Dodge H, Hughes T, Anstey KJ, Cherbuin N, Butterworth P, Ng TP, Gao Q, Reppermund S, Brodaty H, Meguro K, Schupf N, Manly J, Stern Y, Lobo A, Lopez-Anton R, Santabárbara J. COSMIC (Cohort Studies of Memory in an International Consortium): An international consortium to identify risk and protective factors and biomarkers of cognitive ageing and dementia in diverse ethnic and sociocultural groups. BMC Neurol. 2013;13(1):165

Samieri C, Ginder Coupez V, Lorrain S, Letenneur L, Allès B, Féart C, Paineau D, Barberger-Gateau P. Nutrient patterns and risk of fracture in older subjects: results from the Three-City Study. Osteoporos Int. 2013 Apr;24(4):1295-305

Samieri C, Lorrain S, Buaud B, Vaysse C, Berr C, Peuchant E, Cunnane SC, Barberger-Gateau P. Relationship between diet and plasma long-chain n-3 PUFA in older people:Impact of Apolipoprotein E genotype. J Lipid Res. 2013;54(9):2559-67. Epub 2013 Jun 25

Satizabal CL, Zhu YC, Dufouil C, Tzourio C. Inflammatory Proteins and the Severity of Dilated Virchow-Robin Spaces in the Elderly. J Alzheimers Dis. 2013;33(2):323-8

Schilling S, Destefano AL, Sachdev PS, Choi SH, Mather KA, Decarli CD, Wen W, Høgh P, Raz N, Au R, Beiser A, Wolf PA, Romero JR, Zhu YC, Lunetta KL, Farrer L, Dufouil C, Kuller LH, Mazoyer B, Seshadri S, Tzourio C, Debette S. APOE genotype and MRI markers of cerebrovascular disease: Systematic review and meta-analysis. Neurology. 2013;81(3):292-300

Soisson V, Brailly-Tabard S, Helmer C, Rouaud O, Ancelin ML, Zerhouni C, Guiochon-Mantel A, Scarabin PY. A J-shaped association between plasma testosterone and risk of ischemic arterial event in elderly men: The French 3C cohort study. Maturitas. 2013;75(3):282-8. doi: 10.1016/j.maturitas.2013.04.012. Epub 2013 May 22

Straczek C, Marti-Soler H, Tafflet M, Perier MC, Dupuy AM, Tzourio C, Barberger-Gateau P, Empana JP. Comparable incremental value of standard and nonstandard lipids for coronary heart disease risk assessment in elderly adults: the three city study. J Am Geriatr Soc. 2013;61(7):1234-6. doi: 10.1111/jgs.12347

Tang W, Teichert M, Chasman DI, Heit JA, Morange PE, Li G, Pankratz N, Leebeek FW, Paré G, de Andrade M, Tzourio C, Psaty BM, Basu S, Ruiter R, Rose L, Armasu SM, Lumley T, Heckbert SR, Uitterlinden AG, Lathrop M, Rice KM, Cushman M, Hofman A, Lambert JC, Glazer NL, Pankow JS, Witteman JC, Amouyel P, Bis JC, Bovill EG, Kong X, Tracy RP, Boerwinkle E, Rotter JI, Trégouët DA, Loth DW, Stricker BH, Ridker PM, Folsom AR, Smith NL.A Genome-Wide Association Study for Venous Thromboembolism: The Extended Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium. Genet Epidemiol. 2013;37(5):512-21. Epub 2013 May 5

Alpérovitch A, Blachier M, Soumaré A, Ritchie K, Dartigues JF, Richard-Harston S, Tzourio C. Blood pressure variability and risk of dementia in an elderly cohort, the Three-City Study. Alzheimers Dement. 2014;10(5 Suppl):S330-7. Epub 2013 Aug 15

Avila-Funes JA, Meillon C, González-Colaço Harmand M, Tzourio C, Dartigues JF, Amieva H. Association between frailty and carotid central structure changes: the Three-City Study. J Am Geriatr Soc. 2014;62(10):1906-11. Epub 2014 Oct 3.

Ancelin ML, Ripoche E, Dupuy AM, Samieri C, Rouaud O, Berr C, Carrière I, Ritchie K. Gender-specific associations between lipids and cognitive decline in the elderly. Eur Neuropsychopharmacol. 2014;24(7):1056-66. Epub 2014 Feb 17

Asayama K, Thijs L, Brguljan-Hitij J, Niiranen TJ, Hozawa A, Boggia J, Aparicio LS, Hara A, Johansson JK, Ohkubo T, Tzourio C, Stergiou GS, Sandoya E, Tsuji I, Jula AM, Imai Y, Staessen JA; International Database of Home Blood Pressure in Relation to Cardiovascular Outcome (IDHOCO) investigators. Risk stratification by self-measured home blood pressure across categories of conventional blood pressure: a participant-level meta-analysis. PLoS Med. 2014;11(1):e1001591. Epub 2014 Jan 21

Barberger-Gateau P. Nutrition and brain aging: how can we move ahead? Eur J Clin Nutr. 2014;68(11):1245-9. Epub 2014 Aug 27.

Benitez BA, Jin SC, Guerreiro R, Graham R, Lord J, Harold D, Sims R, Lambert JC, Gibbs JR, Bras J, Sassi C, Harari O, Bertelsen S, Lupton MK, Powell J, Bellenguez C, Brown K, Medway C, Haddick PC, van der Brug MP, Bhangale T, Ortmann W, Behrens T, Mayeux R, Pericak-Vance MA, Farrer LA, Schellenberg GD, Haines JL, Turton J, Braae A, Barber I, Fagan AM, Holtzman DM, Morris JC; 3C Study Group; EADI consortium; Alzheimer’s Disease Genetic Consortium (ADGC); Alzheimer’s Disease Neuroimaging Initiative (ADNI); GERAD Consortium, Williams J, Kauwe JS, Amouyel P, Morgan K, Singleton A, Hardy J, Goate AM, Cruchaga C. Missense variant in TREML2 protects against Alzheimer’s disease. Neurobiol Aging. 2014;35(6):1510.e19-26. Epub 2013 Dec 21

Bernard C, Helmer C, Dilharreguy B, Amieva H, Auriacombe S, Dartigues JF, Allard M, Catheline G. Time course of brain volume changes in the preclinical phase of Alzheimer’s disease. Alzheimers Dement. 2014;10(2):143-151.e1.Epub 2014 Jan 10

Brickman AM, Schupf N, Manly JJ, Stern Y, Luchsinger JA, Provenzano FA, Narkhede A, Razlighi Q, Collins-Praino L, Artero S, Akbaraly TN, Ritchie K, Mayeux R, Portet F. APOE ε4 and risk for Alzheimer’s disease: do regionally distributed white matter hyperintensities play a role? Alzheimers Dement. 2014;10(6):619-29. Epub 2014 Oct

Carcaillon L, Brailly-Tabard S, Ancelin ML, Rouaud O, Dartigues JF, Guiochon-Mantel A, Scarabin PY. High plasma estradiol interacts with diabetes on risk of dementia in older postmenopausal women. Neurology. 2014;82(6):504-11.Epub 2014 Jan 29

Carcaillon L, Brailly-Tabard S, Ancelin ML, Tzourio C, Foubert-Samier A, Dartigues JF, Guiochon-Mantel A, Scarabin PY. Low testosterone and the risk of dementia in elderly men: Impact of age and education. Alzheimers Dement. 2014;10(5 Suppl):S306-14. Epub 2013 Sep 10.

Carriere I, Pérès K, Ancelin ML, Gourlet V, Berr C, Barberger-Gateau P, Bouillon K, Kivimaki M, Ritchie K, Akbaraly T. Metabolic Syndrome and Disability: Findings From the Prospective Three-City Study. J Gerontol A Biol Sci Med Sci. 2014;69(1):79-86. Epub 2013 Jul 5

Chouraki V, De Bruijn RF, Chapuis J, Bis JC, Reitz C, Schraen S, Ibrahim-Verbaas CA, Grenier-Boley B, Delay C, Rogers R, Demiautte F, Mounier A, Fitzpatrick AL; The Alzheimer’s Disease Neuroimaging Initiative, Berr C, Dartigues JF, Uitterlinden AG, Hofman A, Breteler M, Becker JT, Lathrop M, Schupf N, Alpérovitch A, Mayeux R, van Duijn CM, Buée L, Amouyel P, Lopez OL, Ikram MA, Tzourio C, Lambert JC. A genome-wide association meta-analysis of plasma Aβ peptides concentrations in the elderly. Mol Psychiatry. 2014;19(12):1326-35. Epub 2014 Feb 18.

Cougnard-Grégoire A, Delyfer MN, Korobelnik JF, Rougier MB, Le Goff M, Dartigues JF, Barberger-Gateau P, Delcourt C. Elevated high-density lipoprotein cholesterol and age-related macular degeneration: the Alienor study. PLoS One. 2014;9(3):e90973

Crivello F, Tzourio-Mazoyer N, Tzourio C, Mazoyer B. Longitudinal assessment of global and regional rate of grey matter atrophy in 1,172 healthy older adults: modulation by sex and age. PLoS One. 2014; 9(12):e114478.

Cyprien F, Courtet P, Poulain V, Maller J, Meslin C, Bonafé A, Le Bars E, Ancelin ML, Ritchie K, Artero S. Corpus callosum size may predict late-life depression in women: A 10-year follow-up study. J Affect Disord. 2014;165:16-23. Epub 2014 Apr 24

Debette S, Wolf C, Lambert JC, Crivello F, Soumaré A, Zhu YC, Schilling S, Dufouil C, Mazoyer B, Amouyel P, Tzourio C, Elbaz A. Abdominal obesity and lower gray matter volume: a Mendelian randomization study. Neurobiol Aging. 2014;35(2):378-86. Epub 2013 Aug 31

Delcourt C, Cougnard-Grégoire A, Boniol M, Carrière I, Doré JF, Delyfer MN, Rougier MB, Le Goff M, Dartigues JF, Barberger-Gateau P, Korobelnik JF. Lifetime exposure to ambient ultraviolet radiation and the risk for cataract extraction and age-related macular degeneration: the Alienor Study. Invest Ophthalmol Vis Sci. 2014;55(11):7619-27

Delva F, Edjolo A, Pérès K, Berr C, Barberger-Gateau P, Dartigues JF. Hierarchical structure of the activities of daily living scale in dementia. J Nutr Health Aging. 2014;18(7):698-704

Dong J, Gao J, Nalls M, Gao X, Huang X, Han J, Singleton AB, Chen H; International Parkinson’s Disease Genomics Consortium (IPDGC). Susceptibility loci for pigmentation and melanoma in relation to Parkinson’s disease. Neurobiol Aging. 2014;35(6):1512.e5-10. Epub 2013 Dec 27.

Dumurgier J, Singh-Manoux A, Tavernier B, Tzourio C, Elbaz A. Lipid-Lowering Drugs Associated With Slower Motor Decline in the Elderly Adults. J Gerontol A Biol Sci Med Sci. 2014;69(2):199-206. Epub 2013 Oct 4

Elbejjani M, Fuhrer R, Abrahamowicz M, Mazoyer B, Crivello F, Tzourio C, Dufouil C. Hippocampal atrophy and subsequent depressive symptoms in older men and women: results from a 10-year prospective cohort. Am J Epidemiol. 2014;180(4):385-93. Epub 2014 Aug 1

Escott-Price V, Bellenguez C, Wang LS, Choi SH, Harold D, Jones L, Holmans P, Gerrish A, Vedernikov A, Richards A, DeStefano AL, Lambert JC, Ibrahim-Verbaas CA, Naj AC, Sims R, Jun G, Bis JC, Beecham GW, Grenier-Boley B, Russo G, Thornton-Wells TA, Denning N, Smith AV, Chouraki V, Thomas C, Ikram MA, Zelenika D, Vardarajan BN, Kamatani Y, Lin CF, Schmidt H, Kunkle B, Dunstan ML, Vronskaya M; United Kingdom Brain Expression Consortium, Johnson AD, Ruiz A, Bihoreau MT, Reitz C, Pasquier F, Hollingworth P, Hanon O, Fitzpatrick AL, Buxbaum JD, Campion D, Crane PK, Baldwin C, Becker T, Gudnason V, Cruchaga C, Craig D, Amin N, Berr C, Lopez OL, De Jager PL, Deramecourt V, Johnston JA, Evans D, Lovestone S, Letenneur L, Hernández I, Rubinsztein DC, Eiriksdottir G, Sleegers K, Goate AM, Fiévet N, Huentelman MJ, Gill M, Brown K, Kamboh MI, Keller L, Barberger-Gateau P, McGuinness B, Larson EB, Myers AJ, Dufouil C, Todd S, Wallon D, Love S, Rogaeva E, Gallacher J, George-Hyslop PS, Clarimon J, Lleo A, Bayer A, Tsuang DW, Yu L, Tsolaki M, Bossù P, Spalletta G, Proitsi P, Collinge J, Sorbi S, Garcia FS, Fox NC, Hardy J, Naranjo MC, Bosco P, Clarke R, Brayne C, Galimberti D, Scarpini E, Bonuccelli U, Mancuso M, Siciliano G, Moebus S, Mecocci P, Zompo MD, Maier W, Hampel H, Pilotto A, Frank-García A, Panza F, Solfrizzi V, Caffarra P, Nacmias B, Perry W, Mayhaus M, Lannfelt L, Hakonarson H, Pichler S, Carrasquillo MM, Ingelsson M, Beekly D, Alvarez V, Zou F, Valladares O, Younkin SG, Coto E, Hamilton-Nelson KL, Gu W, Razquin C, Pastor P, Mateo I, Owen MJ, Faber KM, Jonsson PV, Combarros O, O’Donovan MC, Cantwell LB, Soininen H, Blacker D, Mead S, Mosley TH Jr, Bennett DA, Harris TB, Fratiglioni L, Holmes C, de Bruijn RF, Passmore P, Montine TJ, Bettens K, Rotter JI, Brice A, Morgan K, Foroud TM, Kukull WA, Hannequin D, Powell JF, Nalls MA, Ritchie K, Lunetta KL, Kauwe JS, Boerwinkle E, Riemenschneider M, Boada M, Hiltunen M, Martin ER, Schmidt R, Rujescu D, Dartigues JF, Mayeux R, Tzourio C, Hofman A, Nöthen MM, Graff C, Psaty BM, Haines JL, Lathrop M, Pericak-Vance MA, Launer LJ, Van Broeckhoven C, Farrer LA, van Duijn CM, Ramirez A, Seshadri S, Schellenberg GD, Amouyel P, Williams J. Gene-wide analysis detects two new susceptibility genes for Alzheimer’s disease. PLoS One. 2014;9(6):e94661

Global Burden of Metabolic Risk Factors for Chronic Diseases Collaboration. Cardiovascular disease, chronic kidney disease, and diabetes mortality burden of cardiometabolic risk factors from 1980 to 2010: a comparative risk assessment.Lancet Diabetes Endocrinol. 2014;2(8):634-47. Epub 2014 May 16

Gusareva ES, Carrasquillo MM, Bellenguez C, Cuyvers E, Colon S, Graff-Radford NR, Petersen RC, Dickson DW, Mahachie John JM, Bessonov K, Van Broeckhoven C; the GERAD1 Consortium, Harold D, Williams J, Amouyel P, Sleegers K, Ertekin-Taner N, Lambert JC, Van Steen K. Genome-wide association interaction analysis for Alzheimer’s disease. Neurobiol Aging. 2014;35(11):2436-43. Epub 2014 May 28

Herbert A, Cruickshank JK, Laurent S, Boutouyrie P; on behalf of The Reference Values for Arterial Measurements Collaboration; on behalf of The Reference Values for Arterial Measurements Collaboration. Establishing reference values for central blood pressure and its amplification in a general healthy population and according to cardiovascular risk factors. Eur Heart J. 2014;35(44):3122-33. Epub 2014 Aug 11

Hysi PG, Cheng CY, Springelkamp H, Macgregor S, Bailey JN, Wojciechowski R, Vitart V, Nag A, Hewitt AW, Höhn R, Venturini C, Mirshahi A, Ramdas WD, Thorleifsson G, Vithana E, Khor CC, Stefansson AB, Liao J, Haines JL, Amin N, Wang YX, Wild PS, Ozel AB, Li JZ, Fleck BW, Zeller T, Staffieri SE, Teo YY, Cuellar-Partida G, Luo X, Allingham RR, Richards JE, Senft A, Karssen LC, Zheng Y, Bellenguez C, Xu L, Iglesias AI, Wilson JF, Kang JH, van Leeuwen EM, Jonsson V, Thorsteinsdottir U, Despriet DD, Ennis S, Moroi SE, Martin NG, Jansonius NM, Yazar S, Tai ES, Amouyel P, Kirwan J, van Koolwijk LM, Hauser MA, Jonasson F, Leo P, Loomis SJ, Fogarty R, Rivadeneira F, Kearns L, Lackner KJ, de Jong PT, Simpson CL, Pennell CE, Oostra BA, Uitterlinden AG, Saw SM, Lotery AJ, Bailey-Wilson JE, Hofman A, Vingerling JR, Maubaret C, Pfeiffer N, Wolfs RC, Lemij HG, Young TL, Pasquale LR, Delcourt C, Spector TD, Klaver CC, Small KS, Burdon KP, Stefansson K, Wong TY; BMES GWAS Group; NEIGHBORHOOD Consortium; Wellcome Trust Case Control Consortium 2, Viswanathan A, Mackey DA, Craig JE, Wiggs JL, van Duijn CM, Hammond CJ, Aung T. Genome-wide analysis of multi-ancestry cohorts identifies new loci influencing intraocular pressure and susceptibility to glaucoma. Nat Genet. 2014;46(10):1126-30. Epub 2014 Aug 31

Kaffashian S, Tzourio C, Soumaré A, Dufouil C, Zhu Y, Crivello F, Maillard P, Schraen-Maschke S, Mazoyer B, Buée L, Debette S. Plasma β-amyloid and MRI markers of cerebral small vessel disease: Three-City Dijon study. Neurology. 2014;83(22):2038-45. Epub 2014 Oct 29

Malet F, Le Goff M, Colin J, Schweitzer C, Delyfer MN, Korobelnik JF, Rougier MB, Radeau T, Dartigues JF, Delcourt C. Dry eye disease in French elderly subjects: the Alienor Study. Acta Ophthalmol. 2014;92(6):e429-36. Epub 2013 Jun 7

Marie Dit Asse L, Fabrigoule C, Helmer C, Laumon B, Lafont S. Automobile driving in older adults: factors affecting driving restriction in men and women. J Am Geriatr Soc. 2014;62(11):2071-8

Mortamais M, Portet F, Brickman AM, Provenzano FA, Muraskin J, Akbaraly TN, Berr C, Touchon J, Bonafé A, le Bars E, Menjot de Champfleur N, Maller JJ, Meslin C, Sabatier R, Ritchie K, Artero S. Education Modulates the Impact of White Matter Lesions on the Risk of Mild Cognitive Impairment and Dementia. Am J Geriatr Psychiatry. 2014;22(11):1336-45. Epub 2013 Sep 8.

Nalls MA, Saad M, Noyce AJ, Keller MF, Schrag A, Bestwick JP, Traynor BJ, Gibbs JR, Hernandez DG, Cookson MR, Morris HR, Williams N, Gasser T, Heutink P, Wood N, Hardy J, Martinez M, Singleton AB; International Parkinson’s Disease Genomics Consortium (IPDGC); Wellcome Trust Case Control Consortium 2 (WTCCC2); North American Brain Expression Consortium (NABEC); United Kingdom Brain Expression Consortium (UKBEC). Genetic comorbidities in Parkinson’s disease. Hum Mol Genet. 2014;23(3):831-41.Epub 2013 Sep 20

Philipps V, Amieva H, Andrieu S, Dufouil C, Berr C, Dartigues JF, Jacqmin-Gadda H, Proust-Lima C. Normalized Mini-Mental State Examination for Assessing Cognitive Change in Population-Based Brain Aging Studies. Neuroepidemiology. 2014;43(1):15-25. Epub 2014 Sep 18

Rocanin-Arjo A, Cohen W, Carcaillon L, Frère C, Saut N, Letenneur L, Alhenc-Gelas M, Dupuy AM, Bertrand M, Alessi MC, Germain M, Wild PS, Zeller T, Cambien F, Goodall AH, Amouyel P, Scarabin PY, Trégouët DA, Morange PE; CardioGenics Consortium. A meta-analysis of genome-wide association studies identifies ORM1 as a novel gene controlling thrombin generation potential. Blood. 2014;123(5):777-85. Epub 2013 Dec 19

Rist PM, Tzourio C, Elbaz A, Soumaré A, Dufouil C, Mazoyer B, Kurth T. Structural brain lesions and restless legs syndrome: a cross-sectional population-based study. BMJ Open. 2014;4(11):e005938. doi: 10.1136/bmjopen-2014-005938.

Ritchie K, Ancelin ML, Amieva H, Rouaud O, Carrière I. The association between caffeine and cognitive decline: examining alternative causal hypotheses. Int Psychogeriatr. 2014;26(4):581-90. Epub 2014 Jan 15

Ryan J, Artero S, Carrière I, Scali J, Maller JJ, Meslin C, Ritchie K, Scarabin PY, Ancelin ML. Brain volumes in late life: gender, hormone treatment, and estrogen receptor variants. Neurobiol Aging. 2014;35(3):645-54. Epub 2013 Oct 23

Ryan J, Carrière I, Carcaillon L, Dartigues JF, Auriacombe S, Rouaud O, Berr C, Ritchie K, Scarabin PY, Ancelin ML. Estrogen receptor polymorphisms and incident dementia: the prospective 3C study. Alzheimers Dement. 2014;10(1):27-35

Ryan J, Scali J, Carrière I, Amieva H, Rouaud O, Berr C, Ritchie K, Ancelin ML.Impact of a premature menopause on cognitive function in later life. BJOG. 2014;121(13):1729-39. Epub 2014 May 7

Sabia S, Dumurgier J, Tavernier B, Head J, Tzourio C, Elbaz A. Change in walking speed preceding death: results from a prospective longitudinal cohort study. J Gerontol A Biol Sci Med Sci 2014;69(3):354-62. Epub 2013 Aug 2

Scarabin-Carré V, Brailly-Tabard S, Ancelin ML, Maubaret C, Guiochon-Mantel A, Canonico M, Scarabin PY. Plasma estrogen levels, estrogen receptor gene variation and ischemic arterial disease in postmenopausal women: the Three-City prospective Cohort Study. J Clin Endocrinol Metab. 2014;99(8):E1539-46. doi: 10.1210/jc.2013-4472. Epub 2014 May 13

Schilling S, Tzourio C, Dufouil C, Zhu Y, Berr C, Alpérovitch A, Crivello F, Mazoyer B, Debette S. Plasma lipids and cerebral small vessel disease. Neurology. 2014;83(20):1844-52. Epub 2014 Oct 15.

Singh B, Parsaik AK, Mielke MM, Erwin PJ, Knopman DS, Petersen RC, Roberts RO. Association of mediterranean diet with mild cognitive impairment and Alzheimer’s disease: a systematic review and meta-analysis. J Alzheimers Dis. 2014;39(2):271-82. Review.

Seidowsky A, Massy ZA, Metzger M, Stengel B. Resistant hypertension and chronic kidney disease: epidemiology and prognosis.Nephrol Ther. 2014;10(3):137-44. Epub 2014 Apr 13. French.

Torres MJ, Dorigny B, Kuhn M, Berr C, Barberger-Gateau P, Letenneur L. Nutritional status in community-dwelling elderly in france in urban and rural areas. PLoS One. 2014;9(8):e105137

Tzourio C, Laurent S, Debette S. Is hypertension associated with an accelerated aging of the brain? Hypertension. 2014;63(5):894-903. Epub 2014 Feb 24

Yao M, Zhu YC, Soumaré A, Dufouil C, Mazoyer B, Tzourio C, Chabriat H. Hippocampal perivascular spaces are related to aging and blood pressure but not to cognition. Neurobiol Aging. 2014;35(9):2118-25. Epub 2014 Mar 22

Akbaraly TN, Jaussent I, Besset A, Bertrand M, Barberger-Gateau P, Ritchie K, Ferrie JE, Kivimaki M, Dauvilliers Y. Sleep Complaints and Metabolic Syndrome in an Elderly Population: The Three-City Study. Am J Geriatr Psychiatry. 2015;23(8):818-28. Epub 2014 Oct 15 4.2

Alpérovitch A, Kurth T, Bertrand M, Ancelin ML, Helmer C, Debette S, Tzourio C. Primary prevention with lipid lowering drugs and long term risk of vascular events in older people: population based cohort study. BMJ. 2015 May 19;350:h2335. doi: 10.1136/bmj.h2335 17.4

Ancelin ML, Farré A, Carrière I, Ritchie K, Chaudieu I, Ryan J. C-reactive protein gene variants: independent association with late-life depression and circulating protein levels. Transl Psychiatry. 2015 Jan 20;5:e499. doi: 10.1038/tp.2014.145 4.4

Artaud F, Singh-Manoux A, Dugravot A, Tzourio C, Elbaz A. Decline in Fast Gait Speed as a Predictor of Disability in Older Adults. J Am Geriatr Soc. 2015;63(6):1129-36. Epub 2015 Jun 11 4.6

Bernard C, Dilharreguy B, Helmer C, Chanraud S, Amieva H, Dartigues JF, Allard M, Catheline G. PCC characteristics at rest in 10-year memory decliners. Neurobiol Aging. 2015;36(10):2812-20. Epub 2015 Jul 9. 5.0

Blanche P, Proust-Lima C, Loubère L, Berr C, Dartigues JF, Jacqmin-Gadda H. Quantifying and comparing dynamic predictive accuracy of joint models for longitudinal marker and time-to-event in presence of censoring and competing risks. Biometrics. 2015;71(1):102-13. Epub 2014 Oct 13. 1.6

Bousquet J, Anto JM, Berkouk K, Gergen P, Pinto Antunes J, Augé P, Camuzat T, Bringer J, Mercier J, Best N, Bourret R, Akdis M, Arshad SH, Bedbrook A, Berr C, Bush A, Cavalli G, Charles MA, Clavel-Chapelon F, Gillman M, Gold DR, Goldberg M, Holloway JW, Iozzo P, Jacquemin S, Jeandel C, Kauffmann F, Keil T, Koppelman GH, Krauss-Etschmann S, Kuh D, Lehmann S, Lodrup Carlsen KC, Maier D, Méchali M, Melén E, Moatti JP, Momas I, Nérin P, Postma DS, Ritchie K, Robine JM, Samolinski B, Siroux V, Slagboom PE, Smit HA, Sunyer J, Valenta R, Van de Perre P, Verdier JM, Vrijheid M, Wickman M, Yiallouros P, Zins M. Developmental determinants in non-communicable chronic diseases and ageing. Thorax. 2015;70(6):595-7. Epub 2015 Jan 23. 8.6

Brück K, Jager KJ, Dounousi E, Kainz A, Nitsch D, Ärnlöv J, Rothenbacher D, Browne G, Capuano V, Ferraro PM, Ferrieres J, Gambaro G, Guessous I, Hallan S, Kastarinen M, Navis G, Gonzalez AO, Palmieri L, Romundstad S, Spoto B, Stengel B, Tomson C, Tripepi G, Völzke H, Wiȩcek A, Gansevoort R, Schöttker B, Wanner C, Vinhas J, Zoccali C, Van Biesen W, Stel VS; European CKD Burden Consortium. Methodology used in studies reporting chronic kidney disease prevalence: a systematic literature review. Nephrol Dial Transplant. 2015;30 Suppl 4:iv6-16. 3.6

Carcaillon L, Plichart M, Zureik M, Rouaud O, Majed B, Ritchie K, Tzourio C, Dartigues JF, Empana JP. Carotid plaque as a predictor of dementia in older adults: the Three-City Study. Alzheimers Dement. 2015;11(3):239-48. Epub 2014 Dec 12 12.4

Carrière I, Mura T, Pérès K, Norton J, Jaussent I, Edjolo A, Rouaud O, Berr C, Ritchie K, Ancelin ML. Elderly Benzodiazepine Users at Increased Risk of Activity Limitations: Influence of Chronicity, Indications, and Duration of Action-The Three-City Cohort. Am J Geriatr Psychiatry. 2015;23(8):840-51. Epub 2014 Nov 6 4.2

Catheline G, Amieva H, Dilharreguy B, Bernard C, Duperron MG, Helmer C, Dartigues JF, Allard M. Semantic retrieval over time in the aging brain: Structural evidence of hippocampal contribution. Hippocampus. 2015;25(9):1008-16. Epub 2015 Mar 25 4.2

Charroud C, Steffener J, Bars EL, Deverdun J, Bonafe A, Abdennour M, Portet F, Molino F, Stern Y, Ritchie K, Champfleur NM, Akbaraly TN. Working memory activation of neural networks in the elderly as a function of information processing phase and task complexity. Neurobiol Learn Mem. 2015; 125:211-23. Epub 2015 Oct 8 3.6

Chauhan G, Adams HH, Bis JC, Weinstein G, Yu L, Töglhofer AM, Smith AV, J van der Lee S, Gottesman RF, Thomson R, Wang J, Yang Q, Niessen WJ, Lopez OL, Becker JT, Phan TG, Beare RJ, Arfanakis K, Fleischman D, Vernooij MW, Mazoyer B, Schmidt H, Srikanth V, Knopman DS, Jack CR Jr, Amouyel P, Hofman A, DeCarli C, Tzourio C, van Duijn CM, Bennett DA, Schmidt R, Longstreth WT Jr, Mosley TH, Fornage M, Launer LJ, Seshadri S, Ikram MA, Debette S. Association of Alzheimer’s disease GWAS loci with MRI markers of brain aging. Neurobiol Aging. 2015;36(4):1765.e7-16. Epub 2015 Jan 6 5.0

Cougnard-Grégoire A, Merle BM, Korobelnik JF, Rougier MB, Delyfer MN, Féart C, Le Goff M, Dartigues JF, Barberger-Gateau P, Delcourt C. Vitamin D Deficiency in Community-Dwelling Elderly Is Not Associated with Age-Related Macular Degeneration. J Nutr. 2015;145(8):1865-72. Epub 2015 Jun 17. 3.9

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Luciano M, Marioni RE, Valdés Hernández M, Muñoz Maniega S, Hamilton IF, Royle NA; Generation Scotland, Chauhan G, Bis JC, Debette S, DeCarli C, Fornage M, Schmidt R, Ikram MA, Launer LJ, Seshadri S, Bastin ME, Porteous DJ, Wardlaw J, Deary IJ; CHARGE Consortium. Structural Brain MRI Trait Polygenic Score Prediction of Cognitive Abilities. Twin Res Hum Genet. 2015;18(6):738-45. Epub 2015 Oct 2. 2.3

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Pelletier A, Barul C, Féart C, Helmer C, Bernard C, Periot O, Dilharreguy B, Dartigues JF, Allard M, Barberger-Gateau P, Catheline G, Samieri C. Mediterranean diet and preserved brain structural connectivity in older subjects. Alzheimers Dement. 2015;11(9):1023-31. Epub 2015 Jul 17 12.4

Pimouguet C, Delva F, Le Goff M, Stern Y, Pasquier F, Berr C, Tzourio C, Dartigues JF, Helmer C. Survival and early recourse to care for dementia: A population based study. Alzheimers Dement. 2015;11(4):385-93. Epub 2014 Aug 15 12.4

Pimouguet C, Le-Goff M, Rizzuto D, Berr C, Leffondré K, Pérès K, Dartigues JF, Helmer C. Effect of Early Referral to Specialist in Dementia on Institutionalization and Functional Decline: Findings from a Population-Based Study. J Alzheimers Dis. 2015;49(3):819-28 4.2

Potvin O, Catheline G, Bernard C, Meillon C, Bergua V, Allard M, Dartigues JF, Chauveau N, Celsis P, Amieva H. Gray matter characteristics associated with trait anxiety in older adults are moderated by depression. Int Psychogeriatr. 2015;27(11):1813-24. Epub 2015 Jun 10 1.9

Prugger C, Godin O, Perier MC, Ritchie K, Helmer C, Empana JP, Tzourio C, Dufouil C. Longitudinal association of carotid plaque presence and intima-media thickness with depressive symptoms in the elderly: the three-city study. Arterioscler Thromb Vasc Biol. 2015;35(5):1279-83. Epub 2015 Apr 2. 5.5

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Rist PM, Elbaz A, Dufouil C, Tzourio C, Kurth T. Restless Legs Syndrome and Cognitive Function: A Population-based Cross-sectional Study. Am J Med. 2015;128(9):1023.e33-9. Epub 2015 Apr 23. 5.0

Rougier MB, Korobelnik JF, Malet F, Schweitzer C, Delyfer MN, Dartigues JF, Delcourt C, Helmer C. Retinal nerve fibre layer thickness measured with SD-OCT in a population-based study of French elderly subjects: the Alienor study. Acta Ophthalmol. 2015;93(6):539-45. Epub 2015 Jan 1 2.5

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Williams KM, Bertelsen G, Cumberland P, Wolfram C, Verhoeven VJ, Anastasopoulos E, Buitendijk GH, Cougnard-Grégoire A, Creuzot-Garcher C, Erke MG, Hogg R, Höhn R, Hysi P, Khawaja AP, Korobelnik JF, Ried J, Vingerling JR, Bron A, Dartigues JF, Fletcher A, Hofman A, Kuijpers RW, Luben RN, Oxele K, Topouzis F, von Hanno T, Mirshahi A, Foster PJ, van Duijn CM, Pfeiffer N, Delcourt C, Klaver CC, Rahi J, Hammond CJ; European Eye Epidemiology (E(3)) Consortium. Increasing Prevalence of Myopia in Europe and the Impact of Education. Ophthalmology. 2015;122(7):1489-97. Epub 2015 May 13 6.1

Zhang X, Norton J, Carrière I, Ritchie K, Chaudieu I, Ancelin ML. Risk factors for late-onset generalized anxiety disorder: results from a 12-year prospective cohort (the ESPRIT study). Transl Psychiatry. 2015 Mar 31;5:e536. doi: 10.1038/tp.2015.31 5.6

Zhang X, Norton J, Carrière I, Ritchie K, Chaudieu I, Ancelin ML. Generalized anxiety in community-dwelling elderly: Prevalence and clinical characteristics. J Affect Disord. 2015;172:24-29 3.7

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Alassane S, Binquet C, Cottet V, Fleck O, Acar N, Daniel S, Delcourt C, Bretillon L, Bron AM, Creuzot-Garcher C. Relationships of Macular Pigment Optical Density With Plasma Lutein, Zeaxanthin, and Diet in an Elderly Population: The Montrachet Study. Invest Ophthalmol Vis Sci. 2016;57(3):1160-7

Alassane S, Binquet C, Arnould L, Fleck O, Acar N, Delcourt C, Bretillon L, Bron AM, Creuzot-Garcher C. Spatial Distribution of Macular Pigment in an Elderly French Population: The Montrachet Study. Invest Ophthalmol Vis Sci. 2016 Aug 1;57(10):4469-4475

Allès B, Samieri C, Lorrain S, Jutand MA, Carmichael PH, Shatenstein B, Gaudreau P, Payette H, Laurin D, Barberger-Gateau P. Nutrient Patterns and Their Food Sources in Older Persons from France and Quebec: Dietary and Lifestyle Characteristics. Nutrients. 2016 Apr 19;8(4). pii: E225. doi: 10.3390/nu8040225

Artaud F, Singh-Manoux A, Dugravot A, Tavernier B, Tzourio C, Elbaz A. Body mass index trajectories and functional decline in older adults: Three-City Dijon cohort study. Eur J Epidemiol. 2016;31(1):73-83. Epub 2015 Apr 9.

Berr C, Gabelle A, Fievet N, Goldberg M, Zins M, Carriere I. How to optimize the use of biobanks from population-based cohorts in aging research. Biogerontology. 2016;17(1):221-7. Epub 2015 Jun 26

Bergua V, Meillon C, Potvin O, Ritchie K, Tzourio C, Bouisson J, Dartigues JF, Amieva H. Short STAI-Y anxiety scales: validation and normative data for elderly subjects. Aging Ment Health. 2016;20(9):987-95. Epub 2015 Jun 8

Berticat C, Thomas F, Dauvilliers Y, Jaussent I, Ritchie K, Helmer C, Tzourio C, Raymond M, Artero S. Excessive daytime sleepiness and antipathogen drug consumption in the elderly: a test of the immune theory of sleep. Sci Rep. 2016 Mar 21;6:23574. doi: 10.1038/srep23574

Brück K, Stel VS, Gambaro G, Hallan S, Völzke H, Ärnlöv J, Kastarinen M, Guessous I, Vinhas J, Stengel B, Brenner H, Chudek J, Romundstad S, Tomson C, Gonzalez AO, Bello AK, Ferrieres J, Palmieri L, Browne G, Capuano V, Van Biesen W, Zoccali C, Gansevoort R, Navis G, Rothenbacher D, Ferraro PM, Nitsch D, Wanner C, Jager KJ; European CKD Burden Consortium. CKD Prevalence Varies across the European General Population. J Am Soc Nephrol. 2016;27(7):2135-47. Epub 2015 Dec 23

Carrière I, Farré A, Norton J, Wyart M, Tzourio C, Noize P, Pérès K, Fourrier-Réglat A, Ancelin ML. Patterns of selective serotonin reuptake inhibitor use and risk of falls and fractures in community-dwelling elderly people: the Three-City cohort. Osteoporos Int. 2016;27(11):3187-3195. Epub 2016 Jun 16.

Chan H, Cougnard-Grégoire A, Delyfer MN, Combillet F, Rougier MB, Schweitzer C, Dartigues JF, Korobelnik JF, Delcourt C. Multimodal Imaging of Reticular Pseudodrusen in a Population-Based Setting: The Alienor Study. Invest Ophthalmol Vis Sci. 2016;57(7):3058-65

Charroud C, Le Bars E, Deverdun J, Steffener J, Molino F, Abdennour M, Portet F, Bonafe A, Stern Y, Ritchie K, Akbaraly TN, de Champfleur NM. Working Memory Performance is related to Intrinsic Resting State Functional Connectivity changes in Community-dwelling Elderly Cohort. Neurobiol Learn Mem. 2016;132:57-66

Chouraki V, Reitz C, Maury F, Bis JC, Bellenguez C, Yu L, Jakobsdottir J, Mukherjee S, Adams HH, Choi SH, Larson EB, Fitzpatrick A, Uitterlinden AG, de Jager PL, Hofman A, Gudnason V, Vardarajan B, Ibrahim-Verbaas C, van der Lee SJ, Lopez O, Dartigues JF, Berr C, Amouyel P, Bennett DA, van Duijn C, DeStefano AL, Launer LJ, Ikram MA, Crane PK, Lambert JC, Mayeux R, Seshadri S; International Genomics of Alzheimer’s Project. Evaluation of a Genetic Risk Score to Improve Risk Prediction for Alzheimer’s Disease. J Alzheimers Dis. 2016;53(3):921-32

Cougnard-Grégoire A, Merle BM, Korobelnik JF, Rougier MB, Delyfer MN, Le Goff M, Samieri C, Dartigues JF, Delcourt C. Olive Oil Consumption and Age-Related Macular Degeneration: The Alienor Study. PLoS One. 2016;11(7):e0160240. doi: 10.1371/journal.pone.0160240. eCollection 2016

Creuzot-Garcher C, Binquet C, Daniel S, Bretillon L, Acar N, de Lazzer A, Arnould L, Tzourio C, Bron AM, Delcourt C. The Montrachet Study: study design, methodology and analysis of visual acuity and refractive errors in an elderly population. Acta Ophthalmol. 2016;94(2):e90-7. Epub 2015 Oct 15.

Dandine-Roulland C, Bellenguez C, Debette S, Amouyel P, Génin E, Perdry H. Accuracy of heritability estimations in presence of hidden population stratification. Sci Rep. 2016 May 25;6:26471. doi: 10.1038/srep26471

Delay C, Grenier-Boley B, Amouyel P, Dumont J, Lambert JC. miRNA-dependent target regulation: functional characterization of single-nucleotide polymorphisms identified in genome-wide association studies of Alzheimer’s disease. Alzheimers Res Ther. 2016 May 24;8(1):20. doi: 10.1186/s13195-016-0186-x.

Delcourt C, Korobelnik JF, Buitendijk GH, Foster PJ, Hammond CJ, Piermarocchi S, Peto T, Jansonius N, Mirshahi A, Hogg RE, Bretillon L, Topouzis F, Deak G, Grauslund J, Broe R, Souied EH, Creuzot-Garcher C, Sahel J, Daien V, Lehtimäki T, Hense HW, Prokofyeva E, Oexle K, Rahi JS, Cumberland PM, Schmitz-Valckenberg S, Fauser S, Bertelsen G, Hoyng C, Bergen A, Silva R, Wolf S, Lotery A, Chakravarthy U, Fletcher A, Klaver CC. Ophthalmic epidemiology in Europe: the « European Eye Epidemiology » (E3) consortium. Eur J Epidemiol. 2016;31(2):197-210. Epub 2015 Dec 19

Del Gobbo LC, Imamura F, Aslibekyan S, Marklund M, Virtanen JK, Wennberg M, Yakoob MY, Chiuve SE, Dela Cruz L, Frazier-Wood AC, Fretts AM, Guallar E, Matsumoto C, Prem K, Tanaka T, Wu JH, Zhou X, Helmer C, Ingelsson E, Yuan JM, Barberger-Gateau P, Campos H, Chaves PH, Djoussé L, Giles GG, Gómez-Aracena J, Hodge AM, Hu FB, Jansson JH, Johansson I, Khaw KT, Koh WP, Lemaitre RN, Lind L, Luben RN, Rimm EB, Risérus U, Samieri C, Franks PW, Siscovick DS, Stampfer M, Steffen LM, Steffen BT, Tsai MY, van Dam RM, Voutilainen S, Willett WC, Woodward M, Mozaffarian D; Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Fatty Acids and Outcomes Research Consortium (FORCe). ω-3 Polyunsaturated Fatty Acid Biomarkers and Coronary Heart Disease: Pooling Project of 19 Cohort Studies. JAMA Intern Med. 2016;176(8):1155-66

Delva F, Touraine C, Joly P, Edjolo A, Amieva H, Berr C, Rouaud O, Helmer C, Pérès K, Dartigues JF. ADL disability and death in dementia in a French population-based cohort: New insights with an illness-death model. Alzheimers Dement. 2016;12(8):909-16. Epub 2016 Apr 19.

Deverdun J, Akbaraly TN, Charroud C, Abdennour M, Brickman AM, Chemouny S, Steffener J, Portet F, Bonafe A, Stern Y, Ritchie K, Molino F, Le Bars E, Menjot de Champfleur N. Mean arterial pressure change associated with cerebral blood flow in healthy older adults. Neurobiol Aging. 2016;46:49-57. doi: 10.1016/j.neurobiolaging.2016.05.012

Dumanski JP, Lambert JC, Rasi C, Giedraitis V, Davies H, Grenier-Boley B, Lindgren CM, Campion D, Dufouil C; European Alzheimer’s Disease Initiative Investigators, Pasquier F, Amouyel P, Lannfelt L, Ingelsson M, Kilander L, Lind L, Forsberg LA. Mosaic Loss of Chromosome Y in Blood Is Associated with Alzheimer Disease. Am J Hum Genet. 2016;98(6):1208-19

Dumurgier J, Dartigues JF, Gabelle A, Paquet C, Prevot M, Hugon J, Tzourio C. Time Orientation and 10 Years Risk of Dementia in Elderly Adults: The Three-City Study. J Alzheimers Dis. 2016;53(4):1411-8.

Elbejjani M, Fuhrer R, Abrahamowicz M, Mazoyer B, Crivello F, Tzourio C, Dufouil C. Life-Course Socioeconomic Position and Hippocampal Atrophy in a Prospective Cohort of Older Adults. Psychosom Med. 2016 Jul 15.

Fan Q, Verhoeven VJ, Wojciechowski R, Barathi VA, Hysi PG, Guggenheim JA, Höhn R, Vitart V, Khawaja AP, Yamashiro K, Hosseini SM, Lehtimäki T, Lu Y, Haller T, Xie J, Delcourt C, Pirastu M, Wedenoja J, Gharahkhani P, Venturini C, Miyake M, Hewitt AW, Guo X, Mazur J, Huffman JE, Williams KM, Polasek O, Campbell H, Rudan I, Vatavuk Z, Wilson JF, Joshi PK, McMahon G, St Pourcain B, Evans DM, Simpson CL, Schwantes-An TH, Igo RP, Mirshahi A, Cougnard-Gregoire A, Bellenguez C, Blettner M, Raitakari O, Kähönen M, Seppala I, Zeller T, Meitinger T; Consortium for Refractive Error and Myopia (CREAM), Ried JS, Gieger C, Portas L, van Leeuwen EM, Amin N, Uitterlinden AG, Rivadeneira F, Hofman A, Vingerling JR, Wang YX, Wang X, Tai-Hui Boh E, Ikram MK, Sabanayagam C, Gupta P, Tan V, Zhou L, Ho CE, Lim W, Beuerman RW, Siantar R, Tai ES, Vithana E, Mihailov E, Khor CC, Hayward C, Luben RN, Foster PJ, Klein BE, Klein R, Wong HS, Mitchell P, Metspalu A, Aung T, Young TL, He M, Pärssinen O, van Duijn CM, Jin Wang J, Williams C, Jonas JB, Teo YY, Mackey DA, Oexle K, Yoshimura N, Paterson AD, Pfeiffer N, Wong TY, Baird PN, Stambolian D, Wilson JE, Cheng CY, Hammond CJ, Klaver CC, Saw SM, Rahi JS, Korobelnik JF, Kemp JP, Timpson NJ, Smith GD, Craig JE, Burdon KP, Fogarty RD, Iyengar SK, Chew E, Janmahasatian S, Martin NG, MacGregor S, Xu L, Schache M, Nangia V, Panda-Jonas S, Wright AF, Fondran JR, Lass JH, Feng S, Zhao JH, Khaw KT, Wareham NJ, Rantanen T, Kaprio J, Pang CP, Chen LJ, Tam PO, Jhanji V, Young AL, Döring A, Raffel LJ, Cotch MF, Li X, Yip SP, Yap MK, Biino G, Vaccargiu S, Fossarello M, Fleck B, Yazar S, Tideman JW, Tedja M, Deangelis MM, Morrison M, Farrer L, Zhou X, Chen W, Mizuki N, Meguro A, Mäkelä KM. Meta-analysis of gene-environment-wide association scans accounting for education level identifies additional loci for refractive error. Nat Commun. 2016 Mar 29;7:11008. doi: 10.1038/ncomms11008

Feart C, Letenneur L, Helmer C, Samieri C, Schalch W, Etheve S, Delcourt C, Dartigues JF, Barberger-Gateau P. Plasma Carotenoids Are Inversely Associated With Dementia Risk in an Elderly French Cohort. J Gerontol A Biol Sci Med Sci. 2016;71(5):683-8. Epub 2015 Aug 18

Ferland G, Feart C, Presse N, Lorrain S, Bazin F, Helmer C, Berr C, Annweiler C, Rouaud O, Dartigues JF, Fourrier-Reglat A, Barberger-Gateau P. Vitamin K Antagonists and Cognitive Function in Older Adults: The Three-City Cohort Study. J Gerontol A Biol Sci Med Sci. 2016;71(10):1356-62

García-Esquinas E, Rahi B, Peres K, Colpo M, Dartigues JF, Bandinelli S, Feart C, Rodríguez-Artalejo F. Consumption of fruit and vegetables and risk of frailty: a dose-response analysis of 3 prospective cohorts of community-dwelling older adults. Am J Clin Nutr. 2016;104(1):132-42. Epub 2016 May 18.

Grasset L, Brayne C, Joly P, Jacqmin-Gadda H, Peres K, Foubert-Samier A, Dartigues JF, Helmer C. Trends in dementia incidence: Evolution over a 10-year period in France. Alzheimers Dement. 2016;12(3):272-80. Epub 2015 Dec 13.

Grotz C, Meillon C, Amieva H, Stern Y, Dartigues JF, Adam S, Letenneur L. Why Is Later Age at Retirement Beneficial for Cognition? Results from a French Population-based Study. J Nutr Health Aging. 2016;20(5):514-9.

Ibrahim-Verbaas CA, Bressler J, Debette S, Schuur M, Smith AV, Bis JC, Davies G, Trompet S, Smith JA, Wolf C, Chibnik LB, Liu Y, Vitart V, Kirin M, Petrovic K, Polasek O, Zgaga L, Fawns-Ritchie C, Hoffmann P, Karjalainen J, Lahti J, Llewellyn DJ, Schmidt CO, Mather KA, Chouraki V, Sun Q, Resnick SM, Rose LM, Oldmeadow C, Stewart M, Smith BH, Gudnason V, Yang Q, Mirza SS, Jukema JW, deJager PL, Harris TB, Liewald DC, Amin N, Coker LH, Stegle O, Lopez OL, Schmidt R, Teumer A, Ford I, Karbalai N, Becker JT, Jonsdottir MK, Au R, Fehrmann RS, Herms S, Nalls M, Zhao W, Turner ST, Yaffe K, Lohman K, van Swieten JC, Kardia SL, Knopman DS, Meeks WM, Heiss G, Holliday EG, Schofield PW, Tanaka T, Stott DJ, Wang J, Ridker P, Gow AJ, Pattie A, Starr JM, Hocking LJ, Armstrong NJ, McLachlan S, Shulman JM, Pilling LC, Eiriksdottir G, Scott RJ, Kochan NA, Palotie A, Hsieh YC, Eriksson JG, Penman A, Gottesman RF, Oostra BA, Yu L, DeStefano AL, Beiser A, Garcia M, Rotter JI, Nöthen MM, Hofman A, Slagboom PE, Westendorp RG, Buckley BM, Wolf PA, Uitterlinden AG, Psaty BM, Grabe HJ, Bandinelli S, Chasman DI, Grodstein F, Räikkönen K, Lambert JC, Porteous DJ; Generation Scotland, Price JF, Sachdev PS, Ferrucci L, Attia JR, Rudan I, Hayward C, Wright AF, Wilson JF, Cichon S, Franke L, Schmidt H, Ding J, de Craen AJ, Fornage M, Bennett DA, Deary IJ, Ikram MA, Launer LJ, Fitzpatrick AL, Seshadri S, van Duijn CM, Mosley TH. GWAS for executive function and processing speed suggests involvement of the CADM2 gene. Mol Psychiatry. 2016;21(2):189-97. Epub 2015 Apr 14

Jaussent I, Cristol JP, Stengel B, Ancelin ML, Dupuy AM, Besset A, Helmer C, Ritchie K, Berr C, Dauvilliers Y. Impact of sleep disturbances on kidney function decline in the elderly. Eur Respir J. 2016;47(3):860-8. Epub 2015 Dec 2.

Jun G, Ibrahim-Verbaas CA, Vronskaya M, Lambert JC, Chung J, Naj AC, Kunkle BW, Wang LS, Bis JC, Bellenguez C, Harold D, Lunetta KL, Destefano AL, Grenier-Boley B, Sims R, Beecham GW, Smith AV, Chouraki V, Hamilton-Nelson KL, Ikram MA, Fievet N, Denning N, Martin ER, Schmidt H, Kamatani Y, Dunstan ML, Valladares O, Laza AR, Zelenika D, Ramirez A, Foroud TM, Choi SH, Boland A, Becker T, Kukull WA, van der Lee SJ, Pasquier F, Cruchaga C, Beekly D, Fitzpatrick AL, Hanon O, Gill M, Barber R, Gudnason V, Campion D, Love S, Bennett DA, Amin N, Berr C, Tsolaki M, Buxbaum JD, Lopez OL, Deramecourt V, Fox NC, Cantwell LB, Tárraga L, Dufouil C, Hardy J, Crane PK, Eiriksdottir G, Hannequin D, Clarke R, Evans D, Mosley TH Jr, Letenneur L, Brayne C, Maier W, De Jager P, Emilsson V, Dartigues JF, Hampel H, Kamboh MI, de Bruijn RF, Tzourio C, Pastor P, Larson EB, Rotter JI, O’Donovan MC, Montine TJ, Nalls MA, Mead S, Reiman EM, Jonsson PV, Holmes C, St George-Hyslop PH, Boada M, Passmore P, Wendland JR, Schmidt R, Morgan K, Winslow AR, Powell JF, Carasquillo M, Younkin SG, Jakobsdóttir J, Kauwe JS, Wilhelmsen KC, Rujescu D, Nöthen MM, Hofman A, Jones L; IGAP Consortium, Haines JL, Psaty BM, Van Broeckhoven C, Holmans P, Launer LJ, Mayeux R, Lathrop M, Goate AM, Escott-Price V, Seshadri S, Pericak-Vance MA, Amouyel P, Williams J, van Duijn CM, Schellenberg GD, Farrer LA. A novel Alzheimer disease locus located near the gene encoding tau protein. Mol Psychiatry. 2016;21(1):108-117. Epub 2015 Mar 17

Kaboré J, Metzger M, Helmer C, Berr C, Tzourio C, Massy ZA, Stengel B. Kidney Function Decline and Apparent Treatment-Resistant Hypertension in the Elderly. PLoS One. 2016;11(1):e0146056. doi: 10.1371/journal.pone.0146056. eCollection 2016

Kaffashian S, Tzourio C, Zhu YC, Mazoyer B, Debette S. Differential Effect of White-Matter Lesions and Covert Brain Infarcts on the Risk of Ischemic Stroke and Intracerebral Hemorrhage. Stroke. 2016;47(7):1923-5. Epub 2016 Jun 9.

Kaffashian S, Soumaré A, Zhu YC, Mazoyer B, Debette S, Tzourio C. Long-Term Clinical Impact of Vascular Brain Lesions on Magnetic Resonance Imaging in Older Adults in the Population. Stroke. 2016;47(11):2865-2869.

Khawaja AP, Springelkamp H, Creuzot-Garcher C, Delcourt C, Hofman A, Höhn R, Iglesias AI, Wolfs RC, Korobelnik JF, Silva R, Topouzis F, Williams KM, Bron AM, Buitendijk GH, Cachulo MD, Cougnard-Grégoire A, Dartigues JF, Hammond CJ, Pfeiffer N, Salonikiou A, van Duijn CM, Vingerling JR, Luben RN, Mirshahi A, Lamparter J, Klaver CC, Jansonius NM, Foster PJ; European Eye Epidemiology (E³) Consortium. Associations with intraocular pressure across Europe: The European Eye Epidemiology (E3) Consortium. Eur J Epidemiol. 2016;31(11):1101-1111.

Lefèvre-Arbogast S, Féart C, Dartigues JF, Helmer C, Letenneur L, Samieri C. Dietary B Vitamins and a 10-Year Risk of Dementia in Older Persons. Nutrients. 2016 Nov 26;8(12). pii: E761.

Letois F, Mura T, Scali J, Gutierrez LA, Féart C, Berr C. Nutrition and mortality in the elderly over 10 years of follow-up: the Three-City study. Br J Nutr. 2016;116(5):882-9. Epub 2016 Jul 25

Ma Y, Follis JL, Smith CE, Tanaka T, Manichaikul AW, Chu AY, Samieri C, Zhou X, Guan W, Wang L, Biggs ML, Chen YD, Hernandez DG, Borecki I, Chasman DI, Rich SS, Ferrucci L, Irvin MR, Aslibekyan S, Zhi D, Tiwari HK, Claas SA, Sha J, Kabagambe EK, Lai CQ, Parnell LD, Lee YC, Amouyel P, Lambert JC, Psaty BM, King IB, Mozaffarian D, McKnight B, Bandinelli S, Tsai MY, Ridker PM, Ding J, Mstat KL, Liu Y, Sotoodehnia N, Barberger-Gateau P, Steffen LM, Siscovick DS, Absher D, Arnett DK, Ordovás JM, Lemaitre RN. Interaction of methylation-related genetic variants with circulating fatty acids on plasma lipids: a meta-analysis of 7 studies and methylation analysis of 3 studies in the Cohorts for Heart and Aging Research in Genomic Epidemiology consortium. Am J Clin Nutr. 2016;103(2):567-78.. Epub 2016 Jan 20

Malik R, Traylor M, Pulit SL, Bevan S, Hopewell JC, Holliday EG, Zhao W, Abrantes P, Amouyel P, Attia JR, Battey TW, Berger K, Boncoraglio GB, Chauhan G, Cheng YC, Chen WM, Clarke R, Cotlarciuc I, Debette S, Falcone GJ, Ferro JM, Gamble DM, Ilinca A, Kittner SJ, Kourkoulis CE, Lemmens R, Levi CR, Lichtner P, Lindgren A, Liu J, Meschia JF, Mitchell BD, Oliveira SA, Pera J, Reiner AP, Rothwell PM, Sharma P, Slowik A, Sudlow CL, Tatlisumak T, Thijs V, Vicente AM, Woo D, Seshadri S, Saleheen D, Rosand J, Markus HS, Worrall BB, Dichgans M; ISGC Analysis Group; METASTROKE collaboration; Wellcome Trust Case Control Consortium 2 (WTCCC2); NINDS Stroke Genetics Network (SiGN). Low-frequency and common genetic variation in ischemic stroke: The METASTROKE collaboration. Neurology. 2016 Mar 29;86(13):1217-26. Epub 2016 Mar

NCD Risk Factor Collaboration (NCD-RisC). Trends in adult body-mass index in 200 countries from 1975 to 2014: a pooled analysis of 1698 population-based measurement studies with 19·2 million participants. Lancet. 2016;387(10026):1377-96.

NCD Risk Factor Collaboration (NCD-RisC). Worldwide trends in diabetes since 1980: a pooled analysis of 751 population-based studies with 4.4 million participants. Lancet. 2016;387(10027):1513-30. Epub 2016 Apr 6.

NCD Risk Factor Collaboration (NCD-RisC). A century of trends in adult human height. Elife. 2016 Jul 26;5. pii: e13410. doi: 10.7554/eLife.13410.

Neurology Working Group of the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium; Stroke Genetics Network (SiGN); International Stroke Genetics Consortium (ISGC). Identification of additional risk loci for stroke and small vessel disease: a meta-analysis of genome-wide association studies. Lancet Neurol. 2016;15(7):695-707. Epub 2016 Apr 7

Norton J, Portet F, Gabelle A, Debette S, Ritchie K, Touchon J, Berr C. Are migraine and non-migrainous headache risk factors for stroke in the elderly? Findings from a 12-year cohort follow-up. Eur J Neurol. 2016;23(9):1463-70. Epub 2016 Jul 11

Pattaro C, Teumer A, Gorski M, Chu AY, Li M, Mijatovic V, Garnaas M, Tin A, Sorice R, Li Y, Taliun D, Olden M, Foster M, Yang Q, Chen MH, Pers TH, Johnson AD, Ko YA, Fuchsberger C, Tayo B, Nalls M, Feitosa MF, Isaacs A, Dehghan A, d’Adamo P, Adeyemo A, Dieffenbach AK, Zonderman AB, Nolte IM, van der Most PJ, Wright AF, Shuldiner AR, Morrison AC, Hofman A, Smith AV, Dreisbach AW, Franke A, Uitterlinden AG, Metspalu A, Tonjes A, Lupo A, Robino A, Johansson Å, Demirkan A, Kollerits B, Freedman BI, Ponte B, Oostra BA, Paulweber B, Krämer BK, Mitchell BD, Buckley BM, Peralta CA, Hayward C, Helmer C, Rotimi CN, Shaffer CM, Müller C, Sala C, van Duijn CM, Saint-Pierre A, Ackermann D, Shriner D, Ruggiero D, Toniolo D, Lu Y, Cusi D, Czamara D, Ellinghaus D, Siscovick DS, Ruderfer D, Gieger C, Grallert H, Rochtchina E, Atkinson EJ, Holliday EG, Boerwinkle E, Salvi E, Bottinger EP, Murgia F, Rivadeneira F, Ernst F, Kronenberg F, Hu FB, Navis GJ, Curhan GC, Ehret GB, Homuth G, Coassin S, Thun GA, Pistis G, Gambaro G, Malerba G, Montgomery GW, Eiriksdottir G, Jacobs G, Li G, Wichmann HE, Campbell H, Schmidt H, Wallaschofski H, Völzke H, Brenner H, Kroemer HK, Kramer H, Lin H, Mateo Leach I, Ford I, Guessous I, Rudan I, Prokopenko I, Borecki I, Heid IM, Kolcic I, Persico I, Jukema JW, Wilson JF, Felix JF, Divers J, Lambert JC, Stafford JM, Gaspoz JM, Smith JA, Faul JD, Wang JJ, Ding J, Hirschhorn JN, Attia J, Whitfield JB, Chalmers J, Viikari J, Coresh J, Denny JC, Karjalainen J, Fernandes JK, Endlich K, Butterbach K, Keene KL, Lohman K, Portas L, Launer LJ, Lyytikäinen LP, Yengo L, Franke L, Ferrucci L, Rose LM, Kedenko L, Rao M, Struchalin M, Kleber ME, Cavalieri M, Haun M, Cornelis MC, Ciullo M, Pirastu M, de Andrade M, McEvoy MA, Woodward M, Adam M, Cocca M, Nauck M, Imboden M, Waldenberger M, Pruijm M, Metzger M, Stumvoll M, Evans MK, Sale MM, Kähönen M, Boban M, Bochud M, Rheinberger M, Verweij N, Bouatia-Naji N, Martin NG, Hastie N, Probst-Hensch N, Soranzo N, Devuyst O, Raitakari O, Gottesman O, Franco OH, Polasek O, Gasparini P, Munroe PB, Ridker PM, Mitchell P, Muntner P, Meisinger C, Smit JH; ICBP Consortium; AGEN Consortium; CARDIOGRAM; CHARGe-Heart Failure Group; ECHOGen Consortium, Kovacs P, Wild PS, Froguel P, Rettig R, Mägi R, Biffar R, Schmidt R, Middelberg RP, Carroll RJ, Penninx BW, Scott RJ, Katz R, Sedaghat S, Wild SH, Kardia SL, Ulivi S, Hwang SJ, Enroth S, Kloiber S, Trompet S, Stengel B, Hancock SJ, Turner ST, Rosas SE, Stracke S, Harris TB, Zeller T, Zemunik T, Lehtimäki T, Illig T, Aspelund T, Nikopensius T, Esko T, Tanaka T, Gyllensten U, Völker U, Emilsson V, Vitart V, Aalto V, Gudnason V, Chouraki V, Chen WM, Igl W, März W, Koenig W, Lieb W, Loos RJ, Liu Y, Snieder H, Pramstaller PP, Parsa A, O’Connell JR, Susztak K, Hamet P, Tremblay J, de Boer IH, Böger CA, Goessling W, Chasman DI, Köttgen A, Kao WH, Fox CS. Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function. Nat Commun. 2016 Jan 21;7:10023. doi: 10.1038/ncomms10023

Péquignot R, Dufouil C, Prugger C, Pérès K, Artero S, Tzourio C, Empana JP. High Level of Depressive Symptoms at Repeated Study Visits and Risk of Coronary Heart Disease and Stroke over 10 Years in Older Adults: The Three-City Study. J Am Geriatr Soc. 2016;64(1):118-25. doi: 10.1111/jgs.13872

Rahi B, Colombet Z, Gonzalez-Colaço Harmand M, Dartigues JF, Boirie Y, Letenneur L, Feart C. Higher Protein but Not Energy Intake Is Associated With a Lower Prevalence of Frailty Among Community-Dwelling Older Adults in the French Three-City Cohort. J Am Med Dir Assoc. 2016;17(7):672.e7-672.e11.

Ritchie K, Carrière I, Berr C, Amieva H, Dartigues JF, Ancelin ML, Ritchie CW. The clinical picture of Alzheimer’s disease in the decade before diagnosis: clinical and biomarker trajectories. J Clin Psychiatry. 2016;77(3):e305-11. doi: 10.4088/JCP.15m09989

Ryan J, Artero S, Carrière I, Maller JJ, Meslin C, Ritchie K, Ancelin ML. GWAS-identified risk variants for major depressive disorder: Preliminary support for an association with late-life depressive symptoms and brain structural alterations. Eur Neuropsychopharmacol. 2016;26(1):113-25. Epub 2015 Sep 9.

Shash D, Kurth T, Bertrand M, Dufouil C, Barberger-Gateau P, Berr C, Ritchie K, Dartigues JF, Bégaud B, Alpérovitch A, Tzourio C. Benzodiazepine, psychotropic medication, and dementia: A population-based cohort study. Alzheimers Dement. 2016;12(5):604-13. Epub 2015 Nov 18

Schweitzer C, Korobelnik JF, Boniol M, Cougnard-Gregoire A, Le Goff M, Malet F, Rougier MB, Delyfer MN, Dartigues JF, Delcourt C. Associations of Biomechanical Properties of the Cornea With Environmental and Metabolic Factors in an Elderly Population: The ALIENOR Study. Invest Ophthalmol Vis Sci. 2016;57(4):2003-11.

Schweitzer C, Korobelnik JF, Le Goff M, Rahimian O, Malet F, Rougier MB, Delyfer MN, Dartigues JF, Delcourt C. Diagnostic Performance of Peripapillary Retinal Nerve Fiber Layer Thickness for Detection of Glaucoma in an Elderly Population: The ALIENOR Study. Invest Ophthalmol Vis Sci. 2016 Nov 1;57(14):5882-5891.

Teumer A, Tin A, Sorice R, Gorski M, Yeo NC, Chu AY, Li M, Li Y, Mijatovic V, Ko YA, Taliun D, Luciani A, Chen MH, Yang Q, Foster MC, Olden M, Hiraki LT, Tayo BO, Fuchsberger C, Dieffenbach AK, Shuldiner AR, Smith AV, Zappa AM, Lupo A, Kollerits B, Ponte B, Stengel B, Krämer BK, Paulweber B, Mitchell BD, Hayward C, Helmer C, Meisinger C, Gieger C, Shaffer CM, Müller C, Langenberg C, Ackermann D, Siscovick D; DCCT/EDIC, Boerwinkle E, Kronenberg F, Ehret GB, Homuth G, Waeber G, Navis G, Gambaro G, Malerba G, Eiriksdottir G, Li G, Wichmann HE, Grallert H, Wallaschofski H, Völzke H, Brenner H, Kramer H, Leach IM, Rudan I, Hillege JL, Beckmann JS, Lambert JC, Luan J, Zhao JH, Chalmers J, Coresh J, Denny JC, Butterbach K, Launer LJ, Ferrucci L, Kedenko L, Haun M, Metzger M, Woodward M, Hoffman MJ, Nauck M, Waldenberger M, Pruijm M, Bochud M, Rheinberger M, Verweij N, Wareham NJ, Endlich N, Soranzo N, Polasek O, van der Harst P, Pramstaller PP, Vollenweider P, Wild PS, Gansevoort RT, Rettig R, Biffar R, Carroll RJ, Katz R, Loos RJ, Hwang SJ, Coassin S, Bergmann S, Rosas SE, Stracke S, Harris TB, Corre T, Zeller T, Illig T, Aspelund T, Tanaka T, Lendeckel U, Völker U, Gudnason V, Chouraki V, Koenig W, Kutalik Z, O’Connell JR, Parsa A, Heid IM, Paterson AD, de Boer IH, Devuyst O, Lazar J, Endlich K, Susztak K, Tremblay J, Hamet P, Jacob HJ, Böger CA, Fox CS, Pattaro C, Köttgen A. Genome-wide Association Studies Identify Genetic Loci Associated with Albuminuria in Diabetes. Diabetes. 2016;65(3):803-17. Epub 2015 Dec 2

Tully PJ, Hanon O, Cosh S, Tzourio C. Diuretic antihypertensive drugs and incident dementia risk: a systematic review, meta-analysis and meta-regression of prospective studies. J Hypertens. 2016;34(6):1027-35.

Tully PJ, Debette S, Dartigues JF, Helmer C, Artero S, Tzourio C. Antihypertensive Drug Use, Blood Pressure Variability, and Incident Stroke Risk in Older Adults: Three-City Cohort Study. Stroke. 2016;47(5):1194-200. Epub 2016 Mar 2

Tully PJ, Péres K, Berr C, Tzourio C. The APOE epsilon 4 polymorphism does not predict late onset depression: the Three-City Study. Neurobiol Aging. 2016;40:191.e9-191.e10. Epub 2015 Dec 31.

Tully PJ, Dartigues JF, Debette S, Helmer C, Artero S, Tzourio C. Dementia risk with antihypertensive use and blood pressure variability: A cohort study. Neurology. 2016;87(6):601-8. Epub 2016 Jul 8.

van der Laan SW, Fall T, Soumaré A, Teumer A, Sedaghat S, Baumert J, Zabaneh D, van Setten J, Isgum I, Galesloot TE, Arpegård J, Amouyel P, Trompet S, Waldenberger M, Dörr M, Magnusson PK, Giedraitis V, Larsson A, Morris AP, Felix JF, Morrison AC, Franceschini N, Bis JC, Kavousi M, O’Donnell C, Drenos F, Tragante V, Munroe PB, Malik R, Dichgans M, Worrall BB, Erdmann J, Nelson CP, Samani NJ, Schunkert H, Marchini J, Patel RS, Hingorani AD, Lind L, Pedersen NL, de Graaf J, Kiemeney LA, Baumeister SE, Franco OH, Hofman A, Uitterlinden AG, Koenig W, Meisinger C, Peters A, Thorand B, Jukema JW, Eriksen BO, Toft I, Wilsgaard T, Onland-Moret NC, van der Schouw YT, Debette S, Kumari M, Svensson P, van der Harst P, Kivimaki M, Keating BJ, Sattar N, Dehghan A, Reiner AP, Ingelsson E, den Ruijter HM, de Bakker PI, Pasterkamp G, Ärnlöv J, Holmes MV, Asselbergs FW. Cystatin C and Cardiovascular Disease: A Mendelian Randomization Study. J Am Coll Cardiol. 2016;68(9):934-45

van Rheenen W, Shatunov A, Dekker AM, McLaughlin RL, Diekstra FP, Pulit SL, van der Spek RA, Võsa U, de Jong S, Robinson MR, Yang J, Fogh I, van Doormaal PT, Tazelaar GH, Koppers M, Blokhuis AM, Sproviero W, Jones AR, Kenna KP, van Eijk KR, Harschnitz O, Schellevis RD, Brands WJ, Medic J, Menelaou A, Vajda A, Ticozzi N, Lin K, Rogelj B, Vrabec K, Ravnik-Glavač M, Koritnik B, Zidar J, Leonardis L, Grošelj LD, Millecamps S, Salachas F, Meininger V, de Carvalho M, Pinto S, Mora JS, Rojas-García R, Polak M, Chandran S, Colville S, Swingler R, Morrison KE, Shaw PJ, Hardy J, Orrell RW, Pittman A, Sidle K, Fratta P, Malaspina A, Topp S, Petri S, Abdulla S, Drepper C, Sendtner M, Meyer T, Ophoff RA, Staats KA, Wiedau-Pazos M, Lomen-Hoerth C, Van Deerlin VM, Trojanowski JQ, Elman L, McCluskey L, Basak AN, Tunca C, Hamzeiy H, Parman Y, Meitinger T, Lichtner P, Radivojkov-Blagojevic M, Andres CR, Maurel C, Bensimon G, Landwehrmeyer B, Brice A, Payan CA, Saker-Delye S, Dürr A, Wood NW, Tittmann L, Lieb W, Franke A, Rietschel M, Cichon S, Nöthen MM, Amouyel P, Tzourio C, Dartigues JF, Uitterlinden AG, Rivadeneira F, Estrada K, Hofman A, Curtis C, Blauw HM, van der Kooi AJ, de Visser M, Goris A, Weber M, Shaw CE, Smith BN, Pansarasa O, Cereda C, Del Bo R, Comi GP, D’Alfonso S, Bertolin C, Sorarù G, Mazzini L, Pensato V, Gellera C, Tiloca C, Ratti A, Calvo A, Moglia C, Brunetti M, Arcuti S, Capozzo R, Zecca C, Lunetta C, Penco S, Riva N, Padovani A, Filosto M, Muller B, Stuit RJ; PARALS Registry.; SLALOM Group.; SLAP Registry.; FALS Sequencing Consortium.; SLAGEN Consortium.; NNIPPS Study Group., Blair I, Zhang K, McCann EP, Fifita JA, Nicholson GA, Rowe DB, Pamphlett R, Kiernan MC, Grosskreutz J, Witte OW, Ringer T, Prell T, Stubendorff B, Kurth I, Hübner CA, Leigh PN, Casale F, Chio A, Beghi E, Pupillo E, Tortelli R, Logroscino G, Powell J, Ludolph AC, Weishaupt JH, Robberecht W, Van Damme P, Franke L, Pers TH, Brown RH, Glass JD, Landers JE, Hardiman O, Andersen PM, Corcia P, Vourc’h P, Silani V, Wray NR, Visscher PM, de Bakker PI, van Es MA, Pasterkamp RJ, Lewis CM, Breen G, Al-Chalabi A, van den Berg LH, Veldink JH. Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis. Nat Genet. 2016;48(9):1043-8. Epub 2016 Jul 25.

Vivot A, Power MC, Glymour MM, Mayeda ER, Benitez A, Spiro A 3rd, Manly JJ, Proust-Lima C, Dufouil C, Gross AL. Jump, Hop, or Skip: Modeling Practice Effects in Studies of Determinants of Cognitive Change in Older Adults. Am J Epidemiol. 2016;183(4):302-14. Epub 2016 Jan 28

Wyart M, Jaussent I, Ritchie K, Abbar M, Jollant F, Courtet P. Iowa Gambling Task Performance in Elderly Persons with a Lifetime History of Suicidal Acts. Am J Geriatr Psychiatry. 2016;24(5):399-406. Epub 2015 Dec 24

Amadieu C, Lefèvre-Arbogast S, Delcourt C, Dartigues JF, Helmer C, Féart C, Samieri C. Nutrient biomarker patterns and long-term risk of dementia in older adults. Alzheimers Dement. 2017;13(10):1125-1132. Epub 2017 Mar 18

Ancelin ML, Scali J, Norton J, Ritchie K, Dupuy AM, Chaudieu I, Ryan J. The effect of an adverse psychological environment on salivary cortisol levels in the elderly differs by 5-HTTLPR genotype. Neurobiol Stress. 2017;7:38-46

Ancelin ML, Scali J, Norton J, Ritchie K, Dupuy AM, Chaudieu I, Ryan J. Heterogeneity in HPA axis dysregulation and serotonergic vulnerability to depression. Psychoneuroendocrinology. 2017;77:90-94. Epub 2016 Dec 5

Bellenguez C, Charbonnier C, Grenier-Boley B, Quenez O, Le Guennec K, Nicolas G, Chauhan G, Wallon D, Rousseau S, Richard AC, Boland A, Bourque G, Munter HM, Olaso R, Meyer V, Rollin-Sillaire A, Pasquier F, Letenneur L, Redon R, Dartigues JF, Tzourio C, Frebourg T, Lathrop M, Deleuze JF, Hannequin D, Genin E, Amouyel P, Debette S, Lambert JC, Campion D; CNR MAJ collaborators. Contribution to Alzheimer’s disease risk of rare variants in TREM2, SORL1, and ABCA7 in 1779 cases and 1273 controls. Neurobiol Aging. 2017;59:220.e1-220.e9. Epub 2017 Jul 14

Calati R, Courtet P, Norton J, Ritchie K, Artero S. Association between lifetime headache and history of suicide attempts in the elderly. Eur Psychiatry. 2017;41:132-139. Epub 2017 Jan 31

Carrière I, Norton J, Farré A, Wyart M, Tzourio C, Noize P, Pérès K, Fourrier-Réglat A, Ritchie K, Ancelin ML. Antidepressant use and cognitive decline in community-dwelling elderly people – The Three-City Cohort. BMC Med. 2017;15(1):81

Carrière I, Farré A, Proust-Lima C, Ryan J, Ancelin ML, Ritchie K. Chronic and remitting trajectories of depressive symptoms in the elderly. Characterisation and risk factors. Epidemiol Psychiatr Sci. 2017;26(2):146-156. Epub 2016 Jan 15

Chibnik LB, Wolters FJ, Bäckman K, Beiser A, Berr C, Bis JC, Boerwinkle E, Bos D, Brayne C, Dartigues JF, Darweesh SKL, Debette S, Davis-Plourde KL, Dufouil C, Fornage M, Grasset L, Gudnason V, Hadjichrysanthou C, Helmer C, Ikram MA, Ikram MK, Kern S, Kuller LH, Launer L, Lopez OL, Matthews F, Meirelles O, Mosley T, Ower A, Psaty BM, Satizabal CL, Seshadri S, Skoog I, Stephan BCM, Tzourio C, Waziry R, Wong MM, Zettergren A, Hofman A. Trends in the incidence of dementia: design and methods in the Alzheimer Cohorts Consortium. Eur J Epidemiol. 2017;32(10):931-938. Epub 2017 Oct 23

Colijn JM, Buitendijk GHS, Prokofyeva E, Alves D, Cachulo ML, Khawaja AP, Cougnard-Gregoire A, Merle BMJ, Korb C, Erke MG, Bron A, Anastasopoulos E, Meester-Smoor MA, Segato T, Piermarocchi S, de Jong PTVM, Vingerling JR; EYE-RISK consortium, Topouzis F, Creuzot-Garcher C, Bertelsen G, Pfeiffer N, Fletcher AE, Foster PJ, Silva R, Korobelnik JF, Delcourt C, Klaver CCW; European Eye Epidemiology (E3) consortium. Prevalence of Age-Related Macular Degeneration in Europe: The Past and the Future. Ophthalmology. 2017 Dec;124(12):1753-1763. Epub 2017 Jul 14

Cremer A, Soumaré A, Berr C, Dartigues JF, Gabelle A, Gosse P, Tzourio C. Orthostatic Hypotension and Risk of Incident Dementia: Results From a 12-Year Follow-Up of the Three-City Study Cohort. Hypertension. 2017;70(1):44-49. Epub 2017 May 30.

Dufouil C, Beiser AS, McClure LA, Wolf PA, Tzourio C, Howard VJ, Westwood AJ, Himali JJ, Sullivan LM, Aparicio HJ, Kelly-Hayes M, Ritchie K, Kase CS, Pikula A, Romero JR, D’Agostino RB Sr, Samieri C, Vasan RS, Chêne G, Howard G, Seshadri S. A Revised Framingham Stroke Risk Profile to Reflect Temporal Trends. Circulation. 2017;135(12):1145-1159. Epub 2017 Feb 3.

Dumurgier J, Artaud F, Touraine C, Rouaud O, Tavernier B, Dufouil C, Singh-Manoux A, Tzourio C, Elbaz A. Gait Speed and Decline in Gait Speed as Predictors of Incident Dementia. J Gerontol A Biol Sci Med Sci. 2017;72(5):655-661

Duperron MG, Tzourio C, Sargurupremraj M, Mazoyer B, Soumaré A, Schilling S, Amouyel P, Chauhan G, Zhu YC, Debette S. Burden of Dilated Perivascular Spaces, an Emerging Marker of Cerebral Small Vessel Disease, Is Highly Heritable. Stroke. 2018;49(2):282-287Epub 2018 Jan 8

Elbejjani M, Fuhrer R, Abrahamowicz M, Mazoyer B, Crivello F, Tzourio C, Dufouil C. Life-Course Socioeconomic Position and Hippocampal Atrophy in a Prospective Cohort of Older Adults. Psychosom Med. 2017;79(1):14-23.

Feart C, Helmer C, Merle B, Herrmann FR, Annweiler C, Dartigues JF, Delcourt C, Samieri C. Associations of lower vitamin D concentrations with cognitive decline and long-term risk of dementia and Alzheimer’s disease in older adults. Alzheimers Dement. 2017;13(11):1207-1216. Epub 2017 May 16

Frison E, Boirie Y, Peuchant E, Tabue-Teguo M, Barberger-Gateau P, Féart C. Plasma fatty acid biomarkers are associated with gait speed in community-dwelling older adults: The Three-City-Bordeaux study. Clin Nutr. 2017;36(2):416-422. Epub 2015 Dec 18

Gattoussi S, Cougnard-Grégoire A, Delyfer MN, Rougier MB, Schweitzer C, Delcourt C, Korobelnik JF. Vitreomacular Adhesion and Its Association With Age-Related Macular Degeneration in a Population-Based Setting: The Alienor Study. Invest Ophthalmol Vis Sci. 2017;58(4):2180-2186

Gaye B, Canonico M, Perier MC, Samieri C, Berr C, Dartigues JF, Tzourio C, Elbaz A, Empana JP. Ideal Cardiovascular Health, Mortality, and Vascular Events in Elderly Subjects: The Three-City Study. J Am Coll Cardiol. 2017;69(25):3015-3026

Geissler JM; International Parkinson Disease Genomics Consortium members, Romanos M, Gerlach M, Berg D, Schulte C. No genetic association between attention-deficit/hyperactivity disorder (ADHD) and Parkinson’s disease in nine ADHD candidate SNPs. Atten Defic Hyperact Disord. 2017;9(2):121-127. Epub 2017 Feb 7

Gonzalez-Colaço Harmand M, Meillon C, Bergua V, Tabue Teguo M, Dartigues JF, Avila-Funes JA, Amieva H. Comparing the predictive value of three definitions of frailty: Results from the Three-City study. Arch Gerontol Geriatr. 2017;72:153-163. Epub 2017 Jun 17

Gorski M, van der Most PJ, Teumer A, Chu AY, Li M, Mijatovic V, Nolte IM, Cocca M, Taliun D, Gomez F, Li Y, Tayo B, Tin A, Feitosa MF, Aspelund T, Attia J, Biffar R, Bochud M, Boerwinkle E, Borecki I, Bottinger EP, Chen MH, Chouraki V, Ciullo M, Coresh J, Cornelis MC, Curhan GC, d’Adamo AP, Dehghan A, Dengler L, Ding J, Eiriksdottir G, Endlich K, Enroth S, Esko T, Franco OH, Gasparini P, Gieger C, Girotto G, Gottesman O, Gudnason V, Gyllensten U, Hancock SJ, Harris TB, Helmer C, Höllerer S, Hofer E, Hofman A, Holliday EG, Homuth G, Hu FB, Huth C, Hutri-Kähönen N, Hwang SJ, Imboden M, Johansson Å, Kähönen M, König W, Kramer H, Krämer BK, Kumar A, Kutalik Z, Lambert JC, Launer LJ, Lehtimäki T, de Borst MH, Navis G, Swertz M, Liu Y, Lohman K, Loos RJF, Lu Y, Lyytikäinen LP, McEvoy MA, Meisinger C, Meitinger T, Metspalu A, Metzger M, Mihailov E, Mitchell P, Nauck M, Oldehinkel AJ, Olden M, Wjh Penninx B, Pistis G, Pramstaller PP, Probst-Hensch N, Raitakari OT, Rettig R, Ridker PM, Rivadeneira F, Robino A, Rosas SE, Ruderfer D, Ruggiero D, Saba Y, Sala C, Schmidt H, Schmidt R, Scott RJ, Sedaghat S, Smith AV, Sorice R, Stengel B, Stracke S, Strauch K, Toniolo D, Uitterlinden AG, Ulivi S, Viikari JS, Völker U, Vollenweider P, Völzke H, Vuckovic D, Waldenberger M, Jin Wang J, Yang Q, Chasman DI, Tromp G, Snieder H, Heid IM, Fox CS, Köttgen A, Pattaro C, Böger CA, Fuchsberger C. 1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function. Sci Rep. 2017;7:45040. doi: 10.1038/srep45040.

Hibar DP, Adams HH, Jahanshad N, Chauhan G, Stein JL, Hofer E, Renteria ME, Bis JC, Arias-Vasquez A, Ikram MK, Desrivières S, Vernooij MW, Abramovic L, Alhusaini S, Amin N, Andersson M, Arfanakis K, Aribisala BS, Armstrong NJ, Athanasiu L, Axelsson T, Beecham AH, Beiser A, Bernard M, Blanton SH, Bohlken MM, Boks MP, Bralten J, Brickman AM, Carmichael O, Chakravarty MM, Chen Q, Ching CR, Chouraki V, Cuellar-Partida G, Crivello F, Den Braber A, Doan NT, Ehrlich S, Giddaluru S, Goldman AL, Gottesman RF, Grimm O, Griswold ME, Guadalupe T, Gutman BA, Hass J, Haukvik UK, Hoehn D, Holmes AJ, Hoogman M, Janowitz D, Jia T, Jørgensen KN, Karbalai N, Kasperaviciute D, Kim S, Klein M, Kraemer B, Lee PH, Liewald DC, Lopez LM, Luciano M, Macare C, Marquand AF, Matarin M, Mather KA, Mattheisen M, McKay DR, Milaneschi Y, Muñoz Maniega S, Nho K, Nugent AC, Nyquist P, Loohuis LM, Oosterlaan J, Papmeyer M, Pirpamer L, Pütz B, Ramasamy A, Richards JS, Risacher SL, Roiz-Santiañez R, Rommelse N, Ropele S, Rose EJ, Royle NA, Rundek T, Sämann PG, Saremi A, Satizabal CL, Schmaal L, Schork AJ, Shen L, Shin J, Shumskaya E, Smith AV, Sprooten E, Strike LT, Teumer A, Tordesillas-Gutierrez D, Toro R, Trabzuni D, Trompet S, Vaidya D, Van der Grond J, Van der Lee SJ, Van der Meer D, Van Donkelaar MM, Van Eijk KR, Van Erp TG, Van Rooij D, Walton E, Westlye LT, Whelan CD, Windham BG, Winkler AM, Wittfeld K, Woldehawariat G, Wolf C, Wolfers T, Yanek LR, Yang J, Zijdenbos A, Zwiers MP, Agartz I, Almasy L, Ames D, Amouyel P, Andreassen OA, Arepalli S, Assareh AA, Barral S, Bastin ME, Becker DM, Becker JT, Bennett DA, Blangero J, van Bokhoven H, Boomsma DI, Brodaty H, Brouwer RM, Brunner HG, Buckner RL, Buitelaar JK, Bulayeva KB, Cahn W, Calhoun VD, Cannon DM, Cavalleri GL, Cheng CY, Cichon S, Cookson MR, Corvin A, Crespo-Facorro B, Curran JE, Czisch M, Dale AM, Davies GE, De Craen AJ, De Geus EJ, De Jager PL, De Zubicaray GI, Deary IJ, Debette S, DeCarli C, Delanty N, Depondt C, DeStefano A, Dillman A, Djurovic S, Donohoe G, Drevets WC, Duggirala R, Dyer TD, Enzinger C, Erk S, Espeseth T, Fedko IO, Fernández G, Ferrucci L, Fisher SE, Fleischman DA, Ford I, Fornage M, Foroud TM, Fox PT, Francks C, Fukunaga M, Gibbs JR, Glahn DC, Gollub RL, Göring HH, Green RC, Gruber O, Gudnason V, Guelfi S, Håberg AK, Hansell NK, Hardy J, Hartman CA, Hashimoto R, Hegenscheid K, Heinz A, Le Hellard S, Hernandez DG, Heslenfeld DJ, Ho BC, Hoekstra PJ, Hoffmann W, Hofman A, Holsboer F, Homuth G, Hosten N, Hottenga JJ, Huentelman M, Pol HE, Ikeda M, Jack CR Jr, Jenkinson M, Johnson R, Jönsson EG, Jukema JW, Kahn RS, Kanai R, Kloszewska I, Knopman DS, Kochunov P, Kwok JB, Lawrie SM, Lemaître H, Liu X, Longo DL, Lopez OL, Lovestone S, Martinez O, Martinot JL, Mattay VS, McDonald C, McIntosh AM, McMahon FJ, McMahon KL, Mecocci P, Melle I, Meyer-Lindenberg A, Mohnke S, Montgomery GW, Morris DW, Mosley TH, Mühleisen TW, Müller-Myhsok B, Nalls MA, Nauck M, Nichols TE, Niessen WJ, Nöthen MM, Nyberg L, Ohi K, Olvera RL, Ophoff RA, Pandolfo M, Paus T, Pausova Z, Penninx BW, Pike GB, Potkin SG, Psaty BM, Reppermund S, Rietschel M, Roffman JL, Romanczuk-Seiferth N, Rotter JI, Ryten M, Sacco RL, Sachdev PS, Saykin AJ, Schmidt R, Schmidt H, Schofield PR, Sigursson S, Simmons A, Singleton A, Sisodiya SM, Smith C, Smoller JW, Soininen H, Steen VM, Stott DJ, Sussmann JE, Thalamuthu A, Toga AW, Traynor BJ, Troncoso J, Tsolaki M, Tzourio C, Uitterlinden AG, Hernández MC, Van der Brug M, van der Lugt A, van der Wee NJ, Van Haren NE, van ‘t Ent D, Van Tol MJ, Vardarajan BN, Vellas B, Veltman DJ, Völzke H, Walter H, Wardlaw JM, Wassink TH, Weale ME, Weinberger DR, Weiner MW, Wen W, Westman E, White T, Wong TY, Wright CB, Zielke RH, Zonderman AB, Martin NG, Van Duijn CM, Wright MJ, Longstreth WT, Schumann G, Grabe HJ, Franke B, Launer LJ, Medland SE, Seshadri S, Thompson PM, Ikram MA. Novel genetic loci associated with hippocampal volume. Nat Commun. 2017;8:13624. doi: 10.1038/ncomms13624

Kaboré J, Metzger M, Helmer C, Berr C, Tzourio C, Drueke TB, Massy ZA, Stengel B. Hypertension Control, Apparent Treatment Resistance, and Outcomes in the Elderly Population With Chronic Kidney Disease. Kidney Int Rep. 2017 Mar; 2(2): 180–191. Epub 2016 Oct 31

Kuate-Tegueu C, Avila-Funes JA, Simo N, Le Goff M, Amiéva H, Dartigues JF, Tabue-Teguo M. Association of Gait Speed, Psychomotor Speed, and Dementia. J Alzheimers Dis. 2017;60(2):585-592.

Lipnicki DM, Crawford JD, Dutta R, Thalamuthu A, Kochan NA, Andrews G, Lima-Costa MF, Castro-Costa E, Brayne C, Matthews FE, Stephan BC, Lipton RB, Katz MJ, Ritchie K, Scali J, Ancelin ML, Scarmeas N, Yannakoulia M, Dardiotis E, Lam LC, Wong CH, Fung AW, Guaita A, Vaccaro R, Davin A, Kim KW, Han JW, Kim TH, Anstey KJ, Cherbuin N, Butterworth P, Scazufca M, Kumagai S, Chen S, Narazaki K, Ng TP, Gao Q, Reppermund S, Brodaty H, Lobo A, Lopez-Anton R, Santabárbara J, Sachdev PS; Cohort Studies of Memory in an International Consortium (COSMIC). Age-related cognitive decline and associations with sex, education and apolipoprotein E genotype across ethnocultural groups and geographic regions: a collaborative cohort study. PLoS Med. 2017;14(3):e1002261

McLaughlin RL, Schijven D, van Rheenen W, van Eijk KR, O’Brien M, Kahn RS, Ophoff RA, Goris A, Bradley DG, Al-Chalabi A, van den Berg LH, Luykx JJ, Hardiman O, Veldink JH; Project MinE GWAS Consortium; Schizophrenia Working Group of the Psychiatric Genomics Consortium. Genetic correlation between amyotrophic lateral sclerosis and schizophrenia. Nat Commun. 2017 Mar 21;8:14774. doi: 10.1038/ncomms14774

Marie Dit Asse L, Fabrigoule C, Helmer C, Laumon B, Berr C, Rouaud O, Auriacombe S, Lafont S. Gender effect on driving cessation in pre-dementia and dementia phases: results of the 3C population-based study. Int J Geriatr Psychiatry. 2017 Oct;32(10):1049-1058

Méndez-Gómez JL, Rougier MB, Tellouck L, Korobelnik JF, Schweitzer C, Delyfer MN, Amieva H, Dartigues JF, Delcourt C, Helmer C. Peripapillary Retinal Nerve Fiber Layer Thickness and the Evolution of Cognitive Performance in an Elderly Population. Front Neurol. 2017;8:93. doi: 10.3389/fneur.2017.00093. eCollection 2017

Mura T, Baramova M, Gabelle A, Artero S, Dartigues JF, Amieva H, Berr C. Predicting dementia using socio-demographic characteristics and the Free and Cued Selective Reminding Test in the general population. Alzheimers Res Ther. 2017;9(1):21

Naël V, Pérès K, Carrière I, Daien V, Scherlen AC, Arleo A, Korobelnik JF, Delcourt C, Helmer C. Visual Impairment, Undercorrected Refractive Errors, and Activity Limitations in Older Adults: Findings From the Three-City Alienor Study. Invest Ophthalmol Vis Sci. 2017;58(4):2359-2365

NCD Risk Factor Collaboration (NCD-RisC). Worldwide trends in blood pressure from 1975 to 2015: a pooled analysis of 1479 population-based measurement studies with 19·1 million participants. Lancet. 2017;389(10064):37-55. Epub 2016 Nov 16.

NCD Risk Factor Collaboration (NCD-RisC). Worldwide trends in body-mass index, underweight, overweight, and obesity from 1975 to 2016: a pooled analysis of 2416 population-based measurement studies in 128·9 million children, adolescents, and adults. Lancet 2017 16;390(10113):2627-2642. Epub 2017 Oct 10

33. Pelletier A, Bernard C, Dilharreguy B, Helmer C, Le Goff M, Chanraud S, Dartigues JF, Allard M, Amieva H, Catheline GW. Patterns of brain atrophy associated with episodic memory and semantic fluency decline in aging. Aging (Albany NY). 2017;9(3):741-752

Pérès K, Matharan F, Daien V, Nael V, Edjolo A, Bourdel-Marchasson I 1st, Ritchie K, Tzourio C, Delcourt C, Carrière I. Visual Loss and Subsequent Activity Limitations in the Elderly: The French Three-City Cohort. Am J Public Health. 2017;107(4):564-569

Pilleron S, Ajana S, Jutand MA, Helmer C, Dartigues JF, Samieri C, Féart C. Dietary Patterns and 12-Year Risk of Frailty: Results From the Three-City Bordeaux Study. J Am Med Dir Assoc. 2017;18(2):169-175. Epub 2016 Nov 12

Pilleron S, Rajaobelina K, Tabue Teguo M, Dartigues JF, Helmer C, Delcourt C, Rigalleau V, Féart C. Accumulation of advanced glycation end products evaluated by skin autofluorescence and incident frailty in older adults from the Bordeaux Three-City cohort. PLoS One. 2017 Oct 17;12(10):e0186087. doi: 10.1371/journal.pone.0186087. eCollection 2017

Rajaobelina K, Helmer C, Vélayoudom-Céphise FL, Nov S, Farges B, Pupier E, Blanco L, Hugo M, Gin H, Rigalleau V. Progression of skin autofluorescence of AGEs over 4 years in patients with type 1 diabetes. Diabetes Metab Res Rev. 2017;33(7). Epub 2017 Sep 5.

Robak LA, Jansen IE, van Rooij J, Uitterlinden AG, Kraaij R, Jankovic J; International Parkinson’s Disease Genomics Consortium (IPDGC), Heutink P, Shulman JM; IPDGC Consortium members; International Parkinson’s Disease Genomics Consortium (IPDGC). Excessive burden of lysosomal storage disorder gene variants in Parkinson’s disease. Brain. 2017;140(12):3191-3203

Rondeau V, Mauguen A, Laurent A, Berr C, Helmer C. Dynamic prediction models for clustered and interval-censored outcomes: Investigating the intra-couple correlation in the risk of dementia. Stat Methods Med Res. 2017;26(5):2168-2183. Epub 2015 Jul 15

Rouch L, Cestac P, Cool C, Helmer C, Dartigues JF, Berr C, Rouaud O, Vellas B, Andrieu S. Effectiveness of a standardized and specific follow-up in memory centers in patients with Alzheimer’s disease. Curr Alzheimer Res. 2017;14(3):255-267

Ryan J, Pilkington L, Neuhaus K, Ritchie K, Ancelin ML, Saffery R. Investigating the epigenetic profile of the inflammatory gene IL-6 in late-life depression. BMC Psychiatry. 2017;17(1):354. doi: 10.1186/s12888-017-1515-8

Schilling S, Tzourio C, Soumaré A, Kaffashian S, Dartigues JF, Ancelin ML, Samieri C, Dufouil C, Debette S. Differential associations of plasma lipids with incident dementia and dementia subtypes in the 3C Study: A longitudinal, population-based prospective cohort study. PLoS Med. 2017;14(3):e1002265

Sims R, van der Lee SJ, Naj AC, Bellenguez C, Badarinarayan N, Jakobsdottir J, Kunkle BW, Boland A, Raybould R, Bis JC, Martin ER, Grenier-Boley B, Heilmann-Heimbach S, Chouraki V, Kuzma AB, Sleegers K, Vronskaya M, Ruiz A, Graham RR, Olaso R, Hoffmann P, Grove ML, Vardarajan BN, Hiltunen M, Nöthen MM, White CC, Hamilton-Nelson KL, Epelbaum J, Maier W, Choi SH, Beecham GW, Dulary C, Herms S, Smith AV, Funk CC, Derbois C, Forstner AJ, Ahmad S, Li H, Bacq D, Harold D, Satizabal CL, Valladares O, Squassina A, Thomas R, Brody JA, Qu L, Sánchez-Juan P, Morgan T, Wolters FJ, Zhao Y, Garcia FS, Denning N, Fornage M, Malamon J, Naranjo MCD, Majounie E, Mosley TH, Dombroski B, Wallon D, Lupton MK, Dupuis J, Whitehead P, Fratiglioni L, Medway C, Jian X, Mukherjee S, Keller L, Brown K, Lin H, Cantwell LB, Panza F, McGuinness B, Moreno-Grau S, Burgess JD, Solfrizzi V, Proitsi P, Adams HH, Allen M, Seripa D, Pastor P, Cupples LA, Price ND, Hannequin D, Frank-García A, Levy D, Chakrabarty P, Caffarra P, Giegling I, Beiser AS, Giedraitis V, Hampel H, Garcia ME, Wang X, Lannfelt L, Mecocci P, Eiriksdottir G, Crane PK, Pasquier F, Boccardi V, Henández I, Barber RC, Scherer M, Tarraga L, Adams PM, Leber M, Chen Y, Albert MS, Riedel-Heller S, Emilsson V, Beekly D, Braae A, Schmidt R, Blacker D, Masullo C, Schmidt H, Doody RS, Spalletta G, Jr WTL, Fairchild TJ, Bossù P, Lopez OL, Frosch MP, Sacchinelli E, Ghetti B, Yang Q, Huebinger RM, Jessen F, Li S, Kamboh MI, Morris J, Sotolongo-Grau O, Katz MJ, Corcoran C, Dunstan M, Braddel A, Thomas C, Meggy A, Marshall R, Gerrish A, Chapman J, Aguilar M, Taylor S, Hill M, Fairén MD, Hodges A, Vellas B, Soininen H, Kloszewska I, Daniilidou M, Uphill J, Patel Y, Hughes JT, Lord J, Turton J, Hartmann AM, Cecchetti R, Fenoglio C, Serpente M, Arcaro M, Caltagirone C, Orfei MD, Ciaramella A, Pichler S, Mayhaus M, Gu W, Lleó A, Fortea J, Blesa R, Barber IS, Brookes K, Cupidi C, Maletta RG, Carrell D, Sorbi S, Moebus S, Urbano M, Pilotto A, Kornhuber J, Bosco P, Todd S, Craig D, Johnston J, Gill M, Lawlor B, Lynch A, Fox NC, Hardy J; ARUK Consortium, Albin RL, Apostolova LG, Arnold SE, Asthana S, Atwood CS, Baldwin CT, Barnes LL, Barral S, Beach TG, Becker JT, Bigio EH, Bird TD, Boeve BF, Bowen JD, Boxer A, Burke JR, Burns JM, Buxbaum JD, Cairns NJ, Cao C, Carlson CS, Carlsson CM, Carney RM, Carrasquillo MM, Carroll SL, Diaz CC, Chui HC, Clark DG, Cribbs DH, Crocco EA, DeCarli C, Dick M, Duara R, Evans DA, Faber KM, Fallon KB, Fardo DW, Farlow MR, Ferris S, Foroud TM, Galasko DR, Gearing M, Geschwind DH, Gilbert JR, Graff-Radford NR, Green RC, Growdon JH, Hamilton RL, Harrell LE, Honig LS, Huentelman MJ, Hulette CM, Hyman BT, Jarvik GP, Abner E, Jin LW, Jun G, Karydas A, Kaye JA, Kim R, Kowall NW, Kramer JH, LaFerla FM, Lah JJ, Leverenz JB, Levey AI, Li G, Lieberman AP, Lunetta KL, Lyketsos CG, Marson DC, Martiniuk F, Mash DC, Masliah E, McCormick WC, McCurry SM, McDavid AN, McKee AC, Mesulam M, Miller BL, Miller CA, Miller JW, Morris JC, Murrell JR, Myers AJ, O’Bryant S, Olichney JM, Pankratz VS, Parisi JE, Paulson HL, Perry W, Peskind E, Pierce A, Poon WW, Potter H, Quinn JF, Raj A, Raskind M, Reisberg B, Reitz C, Ringman JM, Roberson ED, Rogaeva E, Rosen HJ, Rosenberg RN, Sager MA, Saykin AJ, Schneider JA, Schneider LS, Seeley WW, Smith AG, Sonnen JA, Spina S, Stern RA, Swerdlow RH, Tanzi RE, Thornton-Wells TA, Trojanowski JQ, Troncoso JC, Van Deerlin VM, Van Eldik LJ, Vinters HV, Vonsattel JP, Weintraub S, Welsh-Bohmer KA, Wilhelmsen KC, Williamson J, Wingo TS, Woltjer RL, Wright CB, Yu CE, Yu L, Garzia F, Golamaully F, Septier G, Engelborghs S, Vandenberghe R, De Deyn PP, Fernadez CM, Benito YA, Thonberg H, Forsell C, Lilius L, Kinhult-Stählbom A, Kilander L, Brundin R, Concari L, Helisalmi S, Koivisto AM, Haapasalo A, Dermecourt V, Fievet N, Hanon O, Dufouil C, Brice A, Ritchie K, Dubois B, Himali JJ, Keene CD, Tschanz J, Fitzpatrick AL, Kukull WA, Norton M, Aspelund T, Larson EB, Munger R, Rotter JI, Lipton RB, Bullido MJ, Hofman A, Montine TJ, Coto E, Boerwinkle E, Petersen RC, Alvarez V, Rivadeneira F, Reiman EM, Gallo M, O’Donnell CJ, Reisch JS, Bruni AC, Royall DR, Dichgans M, Sano M, Galimberti D, St George-Hyslop P, Scarpini E, Tsuang DW, Mancuso M, Bonuccelli U, Winslow AR, Daniele A, Wu CK; GERAD/PERADES, CHARGE, ADGC, EADI, Peters O, Nacmias B, Riemenschneider M, Heun R, Brayne C, Rubinsztein DC, Bras J, Guerreiro R, Al-Chalabi A, Shaw CE, Collinge J, Mann D, Tsolaki M, Clarimón J, Sussams R, Lovestone S, O’Donovan MC, Owen MJ, Behrens TW, Mead S, Goate AM, Uitterlinden AG, Holmes C, Cruchaga C, Ingelsson M, Bennett DA, Powell J, Golde TE, Graff C, De Jager PL, Morgan K, Ertekin-Taner N, Combarros O, Psaty BM, Passmore P, Younkin SG, Berr C, Gudnason V, Rujescu D, Dickson DW, Dartigues JF, DeStefano AL, Ortega-Cubero S, Hakonarson H, Campion D, Boada M, Kauwe JK, Farrer LA, Van Broeckhoven C, Ikram MA, Jones L, Haines JL, Tzourio C, Launer LJ, Escott-Price V, Mayeux R, Deleuze JF, Amin N, Holmans PA, Pericak-Vance MA, Amouyel P, van Duijn CM, Ramirez A, Wang LS, Lambert JC, Seshadri S, Williams J, Schellenberg GD. Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer’s disease. Nat Genet. 2017;49(9):1373-1384. Epub 2017 Jul 17

Tabue-Teguo M, Grasset L, Avila-Funes JA, Genuer R, Proust-Lima C, Péres K, Féart C, Amieva H, Harmand MG, Helmer C, Salles N, Rainfray M, Dartigues JF. Prevalence and Co-Occurrence of Geriatric Syndromes in People Aged 75 Years and Older in France: Results From the Bordeaux Three-city Study. J Gerontol A Biol Sci Med Sci. 2017 May 24. doi: 10.1093/gerona/glx068. 

Tully PJ, Tzourio C. Psychiatric correlates of blood pressure variability in the elderly: The Three City cohort study. Physiol Behav. 2017;168:91-97.

Tully PJ, Debette S, Mazoyer B, Tzourio C. White Matter Lesions are Associated with Specific Depressive Symptom Trajectories among Incident Depression and Dementia Populations: Three-City Dijon MRI Study. Am J Geriatr Psychiatry. 2017 Dec;25(12):1311-1321. Epub 2017 Jul 5

Tully PJ, Qchiqach S, Pereira E, Debette S, Mazoyer B, Tzourio C. Development and validation of a priori risk model for extensive white matter lesions in people age 65 years or older: the Dijon MRI study. BMJ Open. 2017;7(12):e018328.

Tzourio C, Hanon O, Godin O, Soumaré A, Dufouil C. Impact of home blood pressure monitoring on blood pressure control in older individuals: a French randomized study. J Hypertens. 2017;35(3):612-620

Veronese N, Cereda E, Stubbs B, Solmi M, Luchini C, Manzato E, Sergi G, Manu P, Harris T, Fontana L, Strandberg T, Amieva H, Dumurgier J, Elbaz A, Tzourio C, Eicholzer M, Rohrmann S, Moretti C, D’Ascenzo F, Quadri G, Polidoro A, Lourenço RA, Moreira VG, Sanchis J, Scotti V, Maggi S, Correll CU. Risk of cardiovascular disease morbidity and mortality in frail and pre-frail older adults: results from a meta-analysis and exploratory meta-regression analysis. Ageing Res Rev. 2017;35:63-73. Epub 2017 Jan 28

Wain LV, Vaez A, Jansen R, Joehanes R, van der Most PJ, Erzurumluoglu AM, O’Reilly PF, Cabrera CP, Warren HR, Rose LM, Verwoert GC, Hottenga JJ, Strawbridge RJ, Esko T, Arking DE, Hwang SJ, Guo X, Kutalik Z, Trompet S, Shrine N, Teumer A, Ried JS, Bis JC, Smith AV, Amin N, Nolte IM, Lyytikäinen LP, Mahajan A, Wareham NJ, Hofer E, Joshi PK, Kristiansson K, Traglia M, Havulinna AS, Goel A, Nalls MA, Sõber S, Vuckovic D, Luan J, Del Greco M F, Ayers KL, Marrugat J, Ruggiero D, Lopez LM, Niiranen T, Enroth S, Jackson AU, Nelson CP, Huffman JE, Zhang W, Marten J, Gandin I, Harris SE, Zemunik T, Lu Y, Evangelou E, Shah N, de Borst MH, Mangino M, Prins BP, Campbell A, Li-Gao R, Chauhan G, Oldmeadow C, Abecasis G, Abedi M, Barbieri CM, Barnes MR, Batini C, Beilby J, Blake T, Boehnke M, Bottinger EP, Braund PS, Brown M, Brumat M, Campbell H, Chambers JC, Cocca M, Collins F, Connell J, Cordell HJ, Damman JJ, Davies G, de Geus EJ, de Mutsert R, Deelen J, Demirkale Y, Doney ASF, Dörr M, Farrall M, Ferreira T, Frånberg M, Gao H, Giedraitis V, Gieger C, Giulianini F, Gow AJ, Hamsten A, Harris TB, Hofman A, Holliday EG, Hui J, Jarvelin MR, Johansson Å, Johnson AD, Jousilahti P, Jula A, Kähönen M, Kathiresan S, Khaw KT, Kolcic I, Koskinen S, Langenberg C, Larson M, Launer LJ, Lehne B, Liewald DCM, Lin L, Lind L, Mach F, Mamasoula C, Menni C, Mifsud B, Milaneschi Y, Morgan A, Morris AD, Morrison AC, Munson PJ, Nandakumar P, Nguyen QT, Nutile T, Oldehinkel AJ, Oostra BA, Org E, Padmanabhan S, Palotie A, Paré G, Pattie A, Penninx BWJH, Poulter N, Pramstaller PP, Raitakari OT, Ren M, Rice K, Ridker PM, Riese H, Ripatti S, Robino A, Rotter JI, Rudan I, Saba Y, Saint Pierre A, Sala CF, Sarin AP, Schmidt R, Scott R, Seelen MA, Shields DC, Siscovick D, Sorice R, Stanton A, Stott DJ, Sundström J, Swertz M, Taylor KD, Thom S, Tzoulaki I, Tzourio C, Uitterlinden AG, Völker U, Vollenweider P, Wild S, Willemsen G, Wright AF, Yao J, Thériault S, Conen D, Attia J, Sever P, Debette S, Mook-Kanamori DO, Zeggini E, Spector TD, van der Harst P, Palmer CNA, Vergnaud AC, Loos RJF, Polasek O, Starr JM, Girotto G, Hayward C, Kooner JS, Lindgren CM, Vitart V, Samani NJ, Tuomilehto J, Gyllensten U, Knekt P, Deary IJ, Ciullo M, Elosua R, Keavney BD, Hicks AA, Scott RA, Gasparini P, Laan M, Liu Y, Watkins H, Hartman CA, Salomaa V, Toniolo D, Perola M, Wilson JF, Schmidt H, Zhao JH, Lehtimäki T, van Duijn CM, Gudnason V, Psaty BM, Peters A, Rettig R, James A, Jukema JW, Strachan DP, Palmas W, Metspalu A, Ingelsson E, Boomsma DI, Franco OH, Bochud M, Newton-Cheh C, Munroe PB, Elliott P, Chasman DI, Chakravarti A, Knight J, Morris AP, Levy D, Tobin MD, Snieder H, Caulfield MJ, Ehret GB. Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney. Hypertension. 2017 Jul 24. pii: HYPERTENSIONAHA.117.09438. doi: 10.1161/HYPERTENSIONAHA.117.09438. [Epub ahead of print]

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Arnould L, Binquet C, Guenancia C, Alassane S, Kawasaki R, Daien V, Tzourio C, Kawasaki Y, Bourredjem A, Bron A, Creuzot-Garcher C. Association between the retinal vascular network with Singapore « I » Vessel Assessment (SIVA) software, cardiovascular history and risk factors in the elderly: The Montrachet study, population-based study. PLoS One. 2018;13(4):e0194694. eCollection 2018.

Bensassi I, Lopez-Castroman J, Maller JJ, Meslin C, Wyart M, Ritchie K, Courtet P, Artero S, Calati R. Smaller hippocampal volume in current but not in past depression in comparison to healthy controls: Minor evidence from an older adults sample. J Psychiatr Res. 2018;102:159-167. Epub 2018 Apr 9

Bis JC, Jian X, Kunkle BW, Chen Y, Hamilton-Nelson KL, Bush WS, Salerno WJ, Lancour D, Ma Y, Renton AE, Marcora E, Farrell JJ, Zhao Y, Qu L, Ahmad S, Amin N, Amouyel P, Beecham GW, Below JE, Campion D, Charbonnier C, Chung J, Crane PK, Cruchaga C, Cupples LA, Dartigues JF, Debette S, Deleuze JF, Fulton L, Gabriel SB, Genin E, Gibbs RA, Goate A, Grenier-Boley B, Gupta N, Haines JL, Havulinna AS, Helisalmi S, Hiltunen M, Howrigan DP, Ikram MA, Kaprio J, Konrad J, Kuzma A, Lander ES, Lathrop M, Lehtimäki T, Lin H, Mattila K, Mayeux R, Muzny DM, Nasser W, Neale B, Nho K, Nicolas G, Patel D, Pericak-Vance MA, Perola M, Psaty BM, Quenez O, Rajabli F, Redon R, Reitz C, Remes AM, Salomaa V, Sarnowski C, Schmidt H, Schmidt M, Schmidt R, Soininen H, Thornton TA, Tosto G, Tzourio C, van der Lee SJ, van Duijn CM, Vardarajan B, Wang W, Wijsman E, Wilson RK, Witten D, Worley KC, Zhang X; Alzheimer’s Disease Sequencing Project, Bellenguez C, Lambert JC, Kurki MI, Palotie A, Daly M, Boerwinkle E, Lunetta KL, Destefano AL, Dupuis J, Martin ER, Schellenberg GD, Seshadri S, Naj AC, Fornage M, Farrer LA. Whole exome sequencing study identifies novel rare and common Alzheimer’s-Associated variants involved in immune response and transcriptional regulation. Mol Psychiatry. 2018 Aug 14. doi: 10.1038/s41380-018-0112-7. 

Butcher L, Pérès K, André P, Morris RH, Walter S, Dartigues JF, Rodriguez-Mañas L, Feart C, Erusalimsky JD; FRAILOMIC consortium. Association between plasma CCL11 (eotaxin-1) and cognitive status in older adults: Differences between rural and urban dwellers. Exp Gerontol. 2018;113:173-179. Epub 2018 Oct 9

Calati R, Maller JJ, Meslin C, Lopez-Castroman J, Ritchie K, Courtet P, Artero S. Repatriation is associated with isthmus cingulate cortex reduction in community-dwelling elderly. World J Biol Psychiatry. 2018;19(6):421-430. Epub 2016 Dec 15

Cosh S, Naël V, Carrière I, Daien V, Amieva H, Delcourt C, Helmer C, The Sense-Cog Consortium. Bidirectional associations of vision and hearing loss with anxiety: prospective findings from the Three-City Study. Age Ageing. 2018;47(4):582-589

Cosh S, Carriere I, Daien V, Amieva H, Tzourio C, Delcourt C, Helmer C; Sense-Cog Consortium. The relationship between hearing loss in older adults and depression over 12 years: Findings from the Three-City prospective cohort study. Int J Geriatr Psychiatry. 2018 Dec;33(12):1654-1661. Epub 2018 Sep 13

Culverhouse RC, Saccone NL, Horton AC, Ma Y, Anstey KJ, Banaschewski T, Burmeister M, Cohen-Woods S, Etain B, Fisher HL, Goldman N, Guillaume S, Horwood J, Juhasz G, Lester KJ, Mandelli L, Middeldorp CM, Olié E, Villafuerte S, Air TM, Araya R, Bowes L, Burns R, Byrne EM, Coffey C, Coventry WL, Gawronski KAB, Glei D, Hatzimanolis A, Hottenga JJ, Jaussent I, Jawahar C, Jennen-Steinmetz C, Kramer JR, Lajnef M, Little K, Zu Schwabedissen HM, Nauck M, Nederhof E, Petschner P, Peyrot WJ, Schwahn C, Sinnamon G, Stacey D, Tian Y, Toben C, Van der Auwera S, Wainwright N, Wang JC, Willemsen G, Anderson IM, Arolt V, Åslund C, Bagdy G, Baune BT, Bellivier F, Boomsma DI, Courtet P, Dannlowski U, de Geus EJC, Deakin JFW, Easteal S, Eley T, Fergusson DM, Goate AM, Gonda X, Grabe HJ, Holzman C, Johnson EO, Kennedy M, Laucht M, Martin NG, Munafò MR, Nilsson KW, Oldehinkel AJ, Olsson CA, Ormel J, Otte C, Patton GC, Penninx BWJH, Ritchie K, Sarchiapone M, Scheid JM, Serretti A, Smit JH, Stefanis NC, Surtees PG, Völzke H, Weinstein M, Whooley M, Nurnberger JI Jr, Breslau N, Bierut LJ. Collaborative meta-analysis finds no evidence of a strong interaction between stress and 5-HTTLPR genotype contributing to the development of depression. Mol Psychiatry. 2018;23(1):133-142. Epub 2017 Apr 4

Danet-Lamasou M, Pérès K, Matharan F, Berr C, Carrière I, Tzourio C, Delcourt C, Bourdel-Marchasson I. Near Visual Impairment Incidence in Relation to Diabetes in Older People: The Three-Cities Study. J Am Geriatr Soc. 2018;66(4):699-705. Epub 2018 Jan 18

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Delcourt C, Le Goff M, von Hanno T, Mirshahi A, Khawaja AP, Verhoeven VJM, Hogg RE, Anastosopoulos E, Cachulo ML, Höhn R, Wolfram C, Bron A, Miotto S, Carrière I, Colijn JM, Buitendijk GHS, Evans J, Nitsch D, Founti P, Yip JLY, Pfeiffer N, Creuzot-Garcher C, Silva R, Piermarocchi S, Topouzis F, Bertelsen G, Foster PJ, Fletcher A, Klaver CCW, Korobelnik JF; European Eye Epidemiology Consortium. The Decreasing Prevalence of Nonrefractive Visual Impairment in Older Europeans: A Meta-analysis of Published and Unpublished Data. Ophthalmology. 2018;125(8):1149-1159. Epub 2018 Mar 13

Duperron MG, Tzourio C, Sargurupremraj M, Mazoyer B, Soumaré A, Schilling S, Amouyel P, Chauhan G, Zhu YC, Debette S. Burden of Dilated Perivascular Spaces, an Emerging Marker of Cerebral Small Vessel Disease, Is Highly Heritable. Stroke. 2018;49(2):282-287. Epub 2018 Jan 8

Elbaz A, Artaud F, Dugravot A, Tzourio C, Singh-Manoux A. The gait speed advantage of taller stature is lost with age. Sci Rep. 2018;8(1):1485.

Evangelou E, Warren HR, Mosen-Ansorena D, Mifsud B, Pazoki R, Gao H, Ntritsos G, Dimou N, Cabrera CP, Karaman I, Ng FL, Evangelou M, Witkowska K, Tzanis E, Hellwege JN, Giri A, Velez Edwards DR, Sun YV, Cho K, Gaziano JM, Wilson PWF, Tsao PS, Kovesdy CP, Esko T, Mägi R, Milani L, Almgren P, Boutin T, Debette S, Ding J, Giulianini F, Holliday EG, Jackson AU, Li-Gao R, Lin WY, Luan J, Mangino M, Oldmeadow C, Prins BP, Qian Y, Sargurupremraj M, Shah N, Surendran P, Thériault S, Verweij N, Willems SM, Zhao JH, Amouyel P, Connell J, de Mutsert R, Doney ASF, Farrall M, Menni C, Morris AD, Noordam R, Paré G, Poulter NR, Shields DC, Stanton A, Thom S, Abecasis G, Amin N, Arking DE, Ayers KL, Barbieri CM, Batini C, Bis JC, Blake T, Bochud M, Boehnke M, Boerwinkle E, Boomsma DI, Bottinger EP, Braund PS, Brumat M, Campbell A, Campbell H, Chakravarti A, Chambers JC, Chauhan G, Ciullo M, Cocca M, Collins F, Cordell HJ, Davies G, de Borst MH, de Geus EJ, Deary IJ, Deelen J, Del Greco M F, Demirkale CY, Dörr M, Ehret GB, Elosua R, Enroth S, Erzurumluoglu AM, Ferreira T, Frånberg M, Franco OH, Gandin I, Gasparini P, Giedraitis V, Gieger C, Girotto G, Goel A, Gow AJ, Gudnason V, Guo X, Gyllensten U, Hamsten A, Harris TB, Harris SE, Hartman CA, Havulinna AS, Hicks AA, Hofer E, Hofman A, Hottenga JJ, Huffman JE, Hwang SJ, Ingelsson E, James A, Jansen R, Jarvelin MR, Joehanes R, Johansson Å, Johnson AD, Joshi PK, Jousilahti P, Jukema JW, Jula A, Kähönen M, Kathiresan S, Keavney BD, Khaw KT, Knekt P, Knight J, Kolcic I, Kooner JS, Koskinen S, Kristiansson K, Kutalik Z, Laan M, Larson M, Launer LJ, Lehne B, Lehtimäki T, Liewald DCM, Lin L, Lind L, Lindgren CM, Liu Y, Loos RJF, Lopez LM, Lu Y, Lyytikäinen LP, Mahajan A, Mamasoula C, Marrugat J, Marten J, Milaneschi Y, Morgan A, Morris AP, Morrison AC, Munson PJ, Nalls MA, Nandakumar P, Nelson CP, Niiranen T, Nolte IM, Nutile T, Oldehinkel AJ, Oostra BA, O’Reilly PF, Org E, Padmanabhan S, Palmas W, Palotie A, Pattie A, Penninx BWJH, Perola M, Peters A, Polasek O, Pramstaller PP, Nguyen QT, Raitakari OT, Ren M, Rettig R, Rice K, Ridker PM, Ried JS, Riese H, Ripatti S, Robino A, Rose LM, Rotter JI, Rudan I, Ruggiero D, Saba Y, Sala CF, Salomaa V, Samani NJ, Sarin AP, Schmidt R, Schmidt H, Shrine N, Siscovick D, Smith AV, Snieder H, Sõber S, Sorice R, Starr JM, Stott DJ, Strachan DP, Strawbridge RJ, Sundström J, Swertz MA, Taylor KD, Teumer A, Tobin MD, Tomaszewski M, Toniolo D, Traglia M, Trompet S, Tuomilehto J, Tzourio C, Uitterlinden AG, Vaez A, van der Most PJ, van Duijn CM, Vergnaud AC, Verwoert GC, Vitart V, Völker U, Vollenweider P, Vuckovic D, Watkins H, Wild SH, Willemsen G, Wilson JF, Wright AF, Yao J, Zemunik T, Zhang W, Attia JR, Butterworth AS, Chasman DI, Conen D, Cucca F, Danesh J, Hayward C, Howson JMM, Laakso M, Lakatta EG, Langenberg C, Melander O, Mook-Kanamori DO, Palmer CNA, Risch L, Scott RA, Scott RJ, Sever P, Spector TD, van der Harst P, Wareham NJ, Zeggini E, Levy D, Munroe PB, Newton-Cheh C, Brown MJ, Metspalu A, Hung AM, O’Donnell CJ, Edwards TL, Psaty BM, Tzoulaki I, Barnes MR, Wain LV, Elliott P, Caulfield MJ; Million Veteran Program. Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits. Nat Genet. 2018;50(10):1412-1425. Epub 2018 Sep 17. Erratum in: Nat Genet. 2018 Dec;50(12):1755.

Franceschini N, Giambartolomei C, de Vries PS, Finan C, Bis JC, Huntley RP, Lovering RC, Tajuddin SM, Winkler TW, Graff M, Kavousi M, Dale C, Smith AV, Hofer E, van Leeuwen EM, Nolte IM, Lu L, Scholz M, Sargurupremraj M, Pitkänen N, Franzén O, Joshi PK, Noordam R, Marioni RE, Hwang SJ, Musani SK, Schminke U, Palmas W, Isaacs A, Correa A, Zonderman AB, Hofman A, Teumer A, Cox AJ, Uitterlinden AG, Wong A, Smit AJ, Newman AB, Britton A, Ruusalepp A, Sennblad B, Hedblad B, Pasaniuc B, Penninx BW, Langefeld CD, Wassel CL, Tzourio C, Fava C, Baldassarre D, O’Leary DH, Teupser D, Kuh D, Tremoli E, Mannarino E, Grossi E, Boerwinkle E, Schadt EE, Ingelsson E, Veglia F, Rivadeneira F, Beutner F, Chauhan G, Heiss G, Snieder H, Campbell H, Völzke H, Markus HS, Deary IJ, Jukema JW, de Graaf J, Price J, Pott J, Hopewell JC, Liang J, Thiery J, Engmann J, Gertow K, Rice K, Taylor KD, Dhana K, Kiemeney LALM, Lind L, Raffield LM, Launer LJ, Holdt LM, Dörr M, Dichgans M, Traylor M, Sitzer M, Kumari M, Kivimaki M, Nalls MA, Melander O, Raitakari O, Franco OH, Rueda-Ochoa OL, Roussos P, Whincup PH, Amouyel P, Giral P, Anugu P, Wong Q, Malik R, Rauramaa R, Burkhardt R, Hardy R, Schmidt R, de Mutsert R, Morris RW, Strawbridge RJ, Wannamethee SG, Hägg S, Shah S, McLachlan S, Trompet S, Seshadri S, Kurl S, Heckbert SR, Ring S, Harris TB, Lehtimäki T, Galesloot TE, Shah T, de Faire U, Plagnol V, Rosamond WD, Post W, Zhu X, Zhang X, Guo X, Saba Y; MEGASTROKE Consortium, Dehghan A, Seldenrijk A, Morrison AC, Hamsten A, Psaty BM, van Duijn CM, Lawlor DA, Mook-Kanamori DO, Bowden DW, Schmidt H, Wilson JF, Wilson JG, Rotter JI, Wardlaw JM, Deanfield J, Halcox J, Lyytikäinen LP, Loeffler M, Evans MK, Debette S, Humphries SE, Völker U, Gudnason V, Hingorani AD, Björkegren JLM, Casas JP, O’Donnell CJ. GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes. Nat Commun. 2018 Dec 3;9(1):5141

Ferrero A, Alassane S, Binquet C, Bretillon L, Acar N, Arnould L, Muselier-Mathieu A, Delcourt C, Bron AM, Creuzot-Garcher C. Dry eye disease in the elderly in a French population-based study (the Montrachet study: Maculopathy, Optic Nerve, nuTRition, neurovAsCular and HEarT diseases): Prevalence and associated factors. Ocul Surf. 2018;16(1):112-119. Epub 2017 Sep 20

Grasset L, Matthews FE, Pérès K, Foubert-Samier A, Helmer C, Dartigues JF, Brayne C. Evolution of dementia diagnosis over time (1988-2013): Evidence from French and English cohorts. Implication for secular trends analyses. Alzheimers Dement (Amst). 2018;10:490-497.. eCollection 2018

Grotz C, Meillon C, Amieva H, Andel R, Dartigues JF, Adam S, Letenneur L. Occupational social and mental stimulation and cognitive decline with advancing age. Age Ageing. 2018;47(1):101-106

Gusareva ES, Twizere JC, Sleegers K, Dourlen P, Abisambra JF, Meier S, Cloyd R, Weiss B, Dermaut B, Bessonov K, van der Lee SJ, Carrasquillo MM, Katsumata Y, Cherkaoui M, Asselbergh B, Ikram MA, Mayeux R, Farrer LA, Haines JL, Pericak-Vance MA, Schellenberg GD; Genetic and Environmental Risk in Alzheimer’s Disease 1 consortium (GERAD1); Alzheimer’s Disease Genetics Consortium (ADGC); European Alzheimer Disease Initiative Investigators (EADI1 Consortium), Sims R, Williams J, Amouyel P, van Duijn CM, Ertekin-Taner N, Van Broeckhoven C, Dequiedt F, Fardo DW, Lambert JC, Van Steen K. Male-specific epistasis between WWC1 and TLN2 genes is associated with Alzheimer’s disease. Neurobiol Aging. 2018;72:188.e3-188.e12. Epub 2018 Aug 9

Harmand MG, Meillon C, Rullier L, Taddé OB, Pimouguet C, Dartigues JF, Bergua V, Amieva H. Description of general practitioners’ practices when suspecting cognitive impairment. Recourse to care in dementia (Recaredem) study. Aging Ment Health. 2018;22(8):1040-1049. Epub 2017 Jun 8

Husson T, Duboc JB, Quenez O, Charbonnier C, Rotharmel M, Cuenca M, Jegouzo X, Richard AC, Frebourg T, Deleuze JF, Boland A, Genin E, Debette S, Tzourio C, Campion D, Nicolas G, Guillin O; FREX Consortium. Identification of potential genetic risk factors for bipolar disorder by whole-exome sequencing. Transl Psychiatry. 2018 Dec 5;8(1):268

Imamura F, Fretts A, Marklund M, Ardisson Korat AV, Yang WS, Lankinen M, Qureshi W, Helmer C, Chen TA, Wong K, Bassett JK, Murphy R, Tintle N, Yu CI, Brouwer IA, Chien KL, Frazier-Wood AC, Del Gobbo LC, Djoussé L, Geleijnse JM, Giles GG, de Goede J, Gudnason V, Harris WS, Hodge A, Hu F; InterAct Consortium, Koulman A, Laakso M, Lind L, Lin HJ, McKnight B, Rajaobelina K, Risérus U, Robinson JG, Samieri C, Siscovick DS, Soedamah-Muthu SS, Sotoodehnia N, Sun Q, Tsai MY, Uusitupa M, Wagenknecht LE, Wareham NJ, Wu JH, Micha R, Forouhi NG, Lemaitre RN, Mozaffarian D; Fatty Acids and Outcomes Research Consortium (FORCE). Fatty acid biomarkers of dairy fat consumption and incidence of type 2 diabetes: A pooled analysis of prospective cohort studies. PLoS Med. 2018;15(10):e1002670. eCollection 2018 Oct

Jian X, Satizabal CL, Smith AV, Wittfeld K, Bis JC, Smith JA, Hsu FC, Nho K, Hofer E, Hagenaars SP, Nyquist PA, Mishra A, Adams HHH, Li S, Teumer A, Zhao W, Freedman BI, Saba Y, Yanek LR, Chauhan G, van Buchem MA, Cushman M, Royle NA, Bryan RN, Niessen WJ, Windham BG, DeStefano AL, Habes M, Heckbert SR, Palmer ND, Lewis CE, Eiriksdottir G, Maillard P, Mathias RA, Homuth G, Valdés-Hernández MDC, Divers J, Beiser AS, Langner S, Rice KM, Bastin ME, Yang Q, Maldjian JA, Starr JM, Sidney S, Risacher SL, Uitterlinden AG, Gudnason VG, Nauck M, Rotter JI, Schreiner PJ, Boerwinkle E, van Duijn CM, Mazoyer B, von Sarnowski B, Gottesman RF, Levy D, Sigurdsson S, Vernooij MW, Turner ST, Schmidt R, Wardlaw JM, Psaty BM, Mosley TH, DeCarli CS, Saykin AJ, Bowden DW, Becker DM, Deary IJ, Schmidt H, Kardia SLR, Ikram MA, Debette S, Grabe HJ, Longstreth WT Jr, Seshadri S, Launer LJ, Fornage M; neuroCHARGE Working Group. Exome Chip Analysis Identifies Low-Frequency and Rare Variants in MRPL38 for White Matter Hyperintensities on Brain Magnetic Resonance Imaging. Stroke. 2018 Aug;49(8):1812-1819.

Lam D, Ancelin ML, Ritchie K, Freak-Poli R, Saffery R, Ryan J. Genotype-dependent associations between serotonin transporter gene (SLC6A4) DNA methylation and late-life depression. BMC Psychiatry. 2018;18(1):282. doi: 10.1186/s12888-018-1850-4

Lam D, Ancelin ML, Ritchie K, Saffery R, Ryan J. DNA methylation and genetic variation of the angiotensin converting enzyme (ACE) in depression. Psychoneuroendocrinology. 2018;88:1-8. Epub 2017 Nov 8

Laouali N, Brailly-Tabard S, Helmer C, Ancelin ML, Tzourio C, Elbaz A, Guiochon-Mantel A, Canonico M. Oestradiol level, oestrogen receptors, and mortality in elderly men: The three-city cohort study. Clin Endocrinol (Oxf). 2018;89(4):514-525.

Laouali N, Brailly-Tabard S, Helmer C, Ancelin ML, Tzourio C, Singh-Manoux A, Dugravot A, Elbaz A, Guiochon-Mantel A, Canonico M. Testosterone and All-Cause Mortality in Older Men: The Role of Metabolic Syndrome. J Endocr Soc. 2018;2(4):322-335. eCollection 2018 Apr 1.

Latourte A, Soumaré A, Bardin T, Perez-Ruiz F, Debette S, Richette P. Uric acid and incident dementia over 12 years of follow-up: a population-based cohort study. Ann Rheum Dis. 2018;77(3):328-335. Epub 2017 Jul 28

Lefèvre-Arbogast S, Gaudout D, Bensalem J, Letenneur L, Dartigues JF, Hejblum BP, Féart C, Delcourt C, Samieri C. Pattern of polyphenol intake and the long-term risk of dementia in older persons. Neurology. 2018;90(22):e1979-e1988. Epub 2018 Apr 27

Letellier N, Gutierrez LA, Carrière I, Gabelle A, Dartigues JF, Dufouil C, Helmer C, Cadot E, Berr C. Sex-specific association between neighborhood characteristics and dementia: The Three-City cohort. Alzheimers Dement. 2018;14(4):473-482. Epub 2017 Nov 2

Malik R, Chauhan G, Traylor M, Sargurupremraj M, Okada Y, Mishra A, Rutten-Jacobs L, Giese AK, van der Laan SW, Gretarsdottir S, Anderson CD, Chong M, Adams HHH, Ago T, Almgren P, Amouyel P, Ay H, Bartz TM, Benavente OR, Bevan S, Boncoraglio GB, Brown RD Jr, Butterworth AS, Carrera C, Carty CL, Chasman DI, Chen WM, Cole JW, Correa A, Cotlarciuc I, Cruchaga C, Danesh J, de Bakker PIW, DeStefano AL, den Hoed M, Duan Q, Engelter ST, Falcone GJ, Gottesman RF, Grewal RP, Gudnason V, Gustafsson S, Haessler J, Harris TB, Hassan A, Havulinna AS, Heckbert SR, Holliday EG, Howard G, Hsu FC, Hyacinth HI, Ikram MA, Ingelsson E, Irvin MR, Jian X, Jiménez-Conde J, Johnson JA, Jukema JW, Kanai M, Keene KL, Kissela BM, Kleindorfer DO, Kooperberg C, Kubo M, Lange LA, Langefeld CD, Langenberg C, Launer LJ, Lee JM, Lemmens R, Leys D, Lewis CM, Lin WY, Lindgren AG, Lorentzen E, Magnusson PK, Maguire J, Manichaikul A, McArdle PF, Meschia JF, Mitchell BD, Mosley TH, Nalls MA, Ninomiya T, O’Donnell MJ, Psaty BM, Pulit SL, Rannikmäe K, Reiner AP, Rexrode KM, Rice K, Rich SS, Ridker PM, Rost NS, Rothwell PM, Rotter JI, Rundek T, Sacco RL, Sakaue S, Sale MM, Salomaa V, Sapkota BR, Schmidt R, Schmidt CO, Schminke U, Sharma P, Slowik A, Sudlow CLM, Tanislav C, Tatlisumak T, Taylor KD, Thijs VNS, Thorleifsson G, Thorsteinsdottir U, Tiedt S, Trompet S, Tzourio C, van Duijn CM, Walters M, Wareham NJ, Wassertheil-Smoller S, Wilson JG, Wiggins KL, Yang Q, Yusuf S, Bis JC, Pastinen T, Ruusalepp A, Schadt EE, Koplev S, Björkegren JLM, Codoni V, Civelek M, Smith NL, Trégouët DA, Christophersen IE, Roselli C, Lubitz SA, Ellinor PT, Tai ES, Kooner JS, Kato N, He J, van der Harst P, Elliott P, Chambers JC, Takeuchi F, Johnson AD, Sanghera DK, Melander O, Jern C, Strbian D, Fernandez-Cadenas I, Longstreth WT Jr, Rolfs A, Hata J, Woo D, Rosand J, Pare G, Hopewell JC, Saleheen D, Stefansson K, Worrall BB, Kittner SJ, Seshadri S, Fornage M, Markus HS, Howson JMM, Kamatani Y, Debette S, Dichgans M, Malik R, Chauhan G, Traylor M, Sargurupremraj M, Okada Y, Mishra A, Rutten-Jacobs L, Giese AK, van der Laan SW, Gretarsdottir S, Anderson CD, Chong M, Adams HHH, Ago T, Almgren P, Amouyel P, Ay H, Bartz TM, Benavente OR, Bevan S, Boncoraglio GB, Brown RD Jr, Butterworth AS, Carrera C, Carty CL, Chasman DI, Chen WM, Cole JW, Correa A, Cotlarciuc I, Cruchaga C, Danesh J, de Bakker PIW, DeStefano AL, Hoed MD, Duan Q, Engelter ST, Falcone GJ, Gottesman RF, Grewal RP, Gudnason V, Gustafsson S, Haessler J, Harris TB, Hassan A, Havulinna AS, Heckbert SR, Holliday EG, Howard G, Hsu FC, Hyacinth HI, Ikram MA, Ingelsson E, Irvin MR, Jian X, Jiménez-Conde J, Johnson JA, Jukema JW, Kanai M, Keene KL, Kissela BM, Kleindorfer DO, Kooperberg C, Kubo M, Lange LA, Langefeld CD, Langenberg C, Launer LJ, Lee JM, Lemmens R, Leys D, Lewis CM, Lin WY, Lindgren AG, Lorentzen E, Magnusson PK, Maguire J, Manichaikul A, McArdle PF, Meschia JF, Mitchell BD, Mosley TH, Nalls MA, Ninomiya T, O’Donnell MJ, Psaty BM, Pulit SL, Rannikmäe K, Reiner AP, Rexrode KM, Rice K, Rich SS, Ridker PM, Rost NS, Rothwell PM, Rotter JI, Rundek T, Sacco RL, Sakaue S, Sale MM, Salomaa V, Sapkota BR, Schmidt R, Schmidt CO, Schminke U, Sharma P, Slowik A, Sudlow CLM, Tanislav C, Tatlisumak T, Taylor KD, Thijs VNS, Thorleifsson G, Thorsteinsdottir U, Tiedt S, Trompet S, Tzourio C, van Duijn CM, Walters M, Wareham NJ, Wassertheil-Smoller S, Wilson JG, Wiggins KL, Yang Q, Yusuf S, Amin N, Aparicio HS, Arnett DK, Attia J, Beiser AS, Berr C, Buring JE, Bustamante M, Caso V, Cheng YC, Choi SH, Chowhan A, Cullell N, Dartigues JF, Delavaran H, Delgado P, Dörr M, Engström G, Ford I, Gurpreet WS, Hamsten A, Heitsch L, Hozawa A, Ibanez L, Ilinca A, Ingelsson M, Iwasaki M, Jackson RD, Jood K, Jousilahti P, Kaffashian S, Kalra L, Kamouchi M, Kitazono T, Kjartansson O, Kloss M, Koudstaal PJ, Krupinski J, Labovitz DL, Laurie CC, Levi CR, Li L, Lind L, Lindgren CM, Lioutas V, Liu YM, Lopez OL, Makoto H, Martinez-Majander N, Matsuda K, Minegishi N, Montaner J, Morris AP, Muiño E, Müller-Nurasyid M, Norrving B, Ogishima S, Parati EA, Peddareddygari LR, Pedersen NL, Pera J, Perola M, Pezzini A, Pileggi S, Rabionet R, Riba-Llena I, Ribasés M, Romero JR, Roquer J, Rudd AG, Sarin AP, Sarju R, Sarnowski C, Sasaki M, Satizabal CL, Satoh M, Sattar N, Sawada N, Sibolt G, Sigurdsson Á, Smith A, Sobue K, Soriano-Tárraga C, Stanne T, Stine OC, Stott DJ, Strauch K, Takai T, Tanaka H, Tanno K, Teumer A, Tomppo L, Torres-Aguila NP, Touze E, Tsugane S, Uitterlinden AG, Valdimarsson EM, van der Lee SJ, Völzke H, Wakai K, Weir D, Williams SR, Wolfe CDA, Wong Q, Xu H, Yamaji T, Sanghera DK, Melander O, Jern C, Strbian D, Fernandez-Cadenas I, Longstreth WT Jr, Rolfs A, Hata J, Woo D, Rosand J, Pare G, Hopewell JC, Saleheen D, Stefansson K, Worrall BB, Kittner SJ, Seshadri S, Fornage M, Markus HS, Howson JMM, Kamatani Y, Debette S, Dichgans M; AFGen Consortium; Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium; International Genomics of Blood Pressure (iGEN-BP) Consortium; INVENT Consortium; STARNET; BioBank Japan Cooperative Hospital Group; COMPASS Consortium; EPIC-CVD Consortium; EPIC-InterAct Consortium; International Stroke Genetics Consortium (ISGC); METASTROKE Consortium; Neurology Working Group of the CHARGE Consortium; NINDS Stroke Genetics Network (SiGN); UK Young Lacunar DNA Study; MEGASTROKE Consortium; MEGASTROKE Consortium. Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes. Nat Genet. 2018;50(4):524-537. Epub 2018 Mar 12

Malik R, Rannikmäe K, Traylor M, Georgakis MK, Sargurupremraj M, Markus HS, Hopewell JC, Debette S, Sudlow CLM, Dichgans M; MEGASTROKE consortium and the International Stroke Genetics Consortium. Genome-wide meta-analysis identifies 3 novel loci associated with stroke. Ann Neurol. 2018;84(6):934-939. Epub 2018 Nov 30

Mauschitz MM, Bonnemaijer PWM, Diers K, Rauscher FG, Elze T, Engel C, Loeffler M, Colijn JM, Ikram MA, Vingerling JR, Williams KM, Hammond CJ, Creuzot-Garcher C, Bron AM, Silva R, Nunes S, Delcourt C, Cougnard-Grégoire A, Holz FG, Klaver CCW, Breteler MMB, Finger RP; European Eye Epidemiology (E3) Consortium. Systemic and Ocular Determinants of Peripapillary Retinal Nerve Fiber Layer Thickness Measurements in the European Eye Epidemiology (E3) Population. Ophthalmology. 2018;125(10):1526-1536. Epub 2018 Apr 30

Meijers-Heijboer H, van Leeuwen EM, Iyengar SK, Lass JH, Hofman A, Rivadeneira F, Uitterlinden AG, Vingerling JR, Lehtimäki T, Raitakari OT, Biino G, Concas MP, Schwantes-An TH, Igo RP Jr, Cuellar-Partida G, Martin NG, Craig JE, Gharahkhani P, Williams KM, Nag A, Rahi JS, Cumberland PM, Delcourt C, Bellenguez C, Ried JS, Bergen AA, Meitinger T, Gieger C, Wong TY, Hewitt AW, Mackey DA, Simpson CL, Pfeiffer N, Pärssinen O, Baird PN, Vitart V, Amin N, van Duijn CM, Bailey-Wilson JE, Young TL, Saw SM, Stambolian D, MacGregor S, Guggenheim JA, Tung JY, Hammond CJ, Klaver CCW. Genome-wide association meta-analysis highlights light-induced signaling as a driver for refractive error. Nat Genet. 2018;50(6):834-848. Epub 2018 May 28.

Méndez-Gómez JL, Pelletier A, Rougier MB, Korobelnik JF, Schweitzer C, Delyfer MN, Catheline G, Monfermé S, Dartigues JF, Delcourt C, Helmer C. Association of Retinal Nerve Fiber Layer Thickness With Brain Alterations in the Visual and Limbic Networks in Elderly Adults Without Dementia. JAMA Netw Open. 2018;1(7):e184406.

Mortamais M, Abdennour M, Bergua V, Tzourio C, Berr C, Gabelle A, Akbaraly TN. Anxiety and 10-Year Risk of Incident Dementia-An Association Shaped by Depressive Symptoms: Results of the Prospective Three-City Study. Front Neurosci. 2018;12:248. eCollection 201

NCD Risk Factor Collaboration (NCD-RisC). Contributions of mean and shape of blood pressure distribution to worldwide trends and variations in raised blood pressure: a pooled analysis of 1018 population-based measurement studies with 88.6 million participants. Int J Epidemiol. 2018 Mar 19. doi: 10.1093/ije/dyy016.

Olson NC, Raffield LM, Lange LA, Lange EM, Longstreth WT Jr, Chauhan G, Debette S, Seshadri S, Reiner AP, Tracy RP. Associations of activated coagulation factor VII and factor VIIa-antithrombin levels with genome-wide polymorphisms and cardiovascular disease risk. J Thromb Haemost. 2018;16(1):19-30. Epub 2017 Dec 8

Peloso GM, van der Lee SJ; International Genomics of Alzheimer’s Project (IGAP), Destefano AL, Seshardi S. Genetically elevated high-density lipoprotein cholesterol through the cholesteryl ester transfer protein gene does not associate with risk of Alzheimer’s disease. Alzheimers Dement (Amst). 2018;10:595-598

Pilleron S, Pérès K, Jutand MA, Helmer C, Dartigues JF, Samieri C, Féart C. Dietary patterns and risk of self-reported activity limitation in older adults from the Three-City Bordeaux Study. Br J Nutr. 2018;120(5):549-556. Epub 2018 Jul 10

Rahi B, Ajana S, Tabue-Teguo M, Dartigues JF, Peres K, Feart C. High adherence to a Mediterranean diet and lower risk of frailty among French older adults community-dwellers: Results from the Three-City-Bordeaux Study. Clin Nutr. 2018;37(4):1293-1298.. Epub 2017 May 31

Rullier L, Meillon C, Bergua V, Pimouguet C, Gonzalez-Colaço Harmand M, Helmer C, Pérès K, Dartigues JF, Amieva H. A comprehensive approach of the determinants of use of care in dementia: the Recaredem (recourse to care in dementia) cross-sectional study. Int Psychogeriatr. 2018:1-11. doi: 10.1017/S1041610218001497. 

Samieri C, Morris MC, Bennett DA, Berr C, Amouyel P, Dartigues JF, Tzourio C, Chasman DI, Grodstein F. Fish Intake, Genetic Predisposition to Alzheimer Disease, and Decline in Global Cognition and Memory in 5 Cohorts of Older Persons. Am J Epidemiol. 2018;187(5):933-940

Samieri C, Perier MC, Gaye B, Proust-Lima C, Helmer C, Dartigues JF, Berr C, Tzourio C, Empana JP. Association of Cardiovascular Health Level in Older Age With Cognitive Decline and Incident Dementia. JAMA. 2018;320(7):657-664.

Satizabal CL, Samieri C, Davis-Plourde KL, Voetsch B, Aparicio HJ, Pase MP, Romero JR, Helmer C, Vasan RS, Kase CS, Debette S, Beiser AS, Seshadri S. APOE and the Association of Fatty Acids With the Risk of Stroke, Coronary Heart Disease, and Mortality. Stroke. 2018;49(12):2822-2829.

Saunier V, Merle BMJ, Delyfer MN, Cougnard-Grégoire A, Rougier MB, Amouyel P, Lambert JC, Dartigues JF, Korobelnik JF, Delcourt C. Incidence of and Risk Factors Associated With Age-Related Macular Degeneration: Four-Year Follow-up From the ALIENOR Study. JAMA Ophthalmol. 2018;136(5):473-481.

Schweitzer C, Cougnard-Gregoire A, Rigalleau V, Dartigues JF, Malet F, Rougier MB, Delyfer MN, Helmer C, Korobelnik JF, Delcourt C. Autofluorescence of Skin Advanced Glycation End Products as a Risk Factor for Open Angle Glaucoma: The ALIENOR Study. Invest Ophthalmol Vis Sci. 2018;59(1):75-84

Tedja MS, Wojciechowski R, Hysi PG, Eriksson N, Furlotte NA, Verhoeven VJM, Iglesias AI, Meester-Smoor MA, Tompson SW, Fan Q, Khawaja AP, Cheng CY, Höhn R, Yamashiro K, Wenocur A, Grazal C, Haller T, Metspalu A, Wedenoja J, Jonas JB, Wang YX, Xie J, Mitchell P, Foster PJ, Klein BEK, Klein R, Paterson AD, Hosseini SM, Shah RL, Williams C, Teo YY, Tham YC, Gupta P, Zhao W, Shi Y, Saw WY, Tai ES, Sim XL, Huffman JE, Polašek O, Hayward C, Bencic G, Rudan I, Wilson JF; CREAM Consortium; 23andMe Research Team; UK Biobank Eye and Vision Consortium, Joshi PK, Tsujikawa A, Matsuda F, Whisenhunt KN, Zeller T, van der Spek PJ, Haak R, Meijers-Heijboer H, van Leeuwen EM, Iyengar SK, Lass JH, Hofman A, Rivadeneira F, Uitterlinden AG, Vingerling JR, Lehtimäki T, Raitakari OT, Biino G, Concas MP, Schwantes-An TH, Igo RP Jr, Cuellar-Partida G, Martin NG, Craig JE, Gharahkhani P, Williams KM, Nag A, Rahi JS, Cumberland PM, Delcourt C, Bellenguez C, Ried JS, Bergen AA, Meitinger T, Gieger C, Wong TY, Hewitt AW, Mackey DA, Simpson CL, Pfeiffer N, Pärssinen O, Baird PN, Vitart V, Amin N, van Duijn CM, Bailey-Wilson JE, Young TL, Saw SM, Stambolian D, MacGregor S, Guggenheim JA, Tung JY, Hammond CJ, Klaver CCW. Genome-wide association meta-analysis highlights light-induced signaling as a driver for refractive error. Nat Genet. 2018;50(6):834-848. Epub 2018 May 28

Tully PJ, Debette S, Tzourio C. The association between systolic blood pressure variability with depression, cognitive decline and white matter hyperintensities: the 3C Dijon MRI study. Psychol Med. 2018;48(9):1444-1453. Epub 2017 Sep 27

Tully PJ, Peters R, Pérès K, Anstey KJ, Tzourio C. Effect of SSRI and calcium channel blockers on depression symptoms and cognitive function in elderly persons treated for hypertension: three city cohort study. Int Psychogeriatr. 2018;30(9):1345-1354. Epub 2018 Mar 21.

Tully PJ, Turnbull DA, Anstey KJ, Beckett N, Beiser AS, Birns J, Brickman AM, Burns NR, Cosh S, de Leeuw PW, Dorstyn D, Elias MF, Wouter Jukema J, Kario K, Kikuya M, Kroon AA, Launer LJ, Mahajan R, McGrath ER, Mooijaart SP, Moll van Charante EP, Nagai M, Ninomiya T, Ohara T, Ohkubo T, Oishi E, Peters R, Richard E, Satoh M, Seshadri S, Stott DJ, van Gool WA, van Middelaar T, Trompet S, Giles K, Drioli-Phillips P, Aaimir U, Connolly F, Tzourio C. VARIABLE BRAIN consortium. The association between blood pressure variability (BPV) with dementia and cognitive function: a systematic review and meta-analysis protocol. Syst Rev. 2018;7(1):163

54. Wagner M, Dartigues JF, Samieri C, Proust-Lima C. Modeling Risk-Factor Trajectories When Measurement Tools Change Sequentially During Follow-up in Cohort Studies: Application to Dietary Habits in Prodromal Dementia. Am J Epidemiol. 2018;187(4):845-854.

Wagner M, Helmer C, Tzourio C, Berr C, Proust-Lima C, Samieri C. Evaluation of the Concurrent Trajectories of Cardiometabolic Risk Factors in the 14 Years Before Dementia.JAMA Psychiatry. 2018;75(10):1033-1042.

Zhu D, Chung HF, Pandeya N, Dobson AJ, Cade JE, Greenwood DC, Crawford SL, Avis NE, Gold EB, Mitchell ES, Woods NF, Anderson D, Brown DE, Sievert LL, Brunner EJ, Kuh D, Hardy R, Hayashi K, Lee JS, Mizunuma H, Giles GG, Bruinsma F, Tillin T, Simonsen MK, Adami HO, Weiderpass E, Canonico M, Ancelin ML, Demakakos P, Mishra GD. Relationships between intensity, duration, cumulative dose, and timing of smoking with age at menopause: A pooled analysis of individual data from 17 observational studies. PLoS Med. 2018;15(11):e1002704. eCollection 2018 Nov

Ajana S, Acar N, Bretillon L, Hejblum BP, Jacqmin-Gadda H, Delcourt C; BLISAR Study Group. Benefits of dimension reduction in penalized regression methods for high-dimensional grouped data: a case study in low sample size. Bioinformatics. 2019;35(19):3628-3634.

Allès B, Samieri C, Jutand MA, Carmichael PH, Shatenstein B, Gaudreau P, Ferland G, Barberger-Gateau P, Laurin D. Nutrient Patterns, Cognitive Function, and Decline in Older Persons: Results from the Three-City and NuAge Studies. Nutrients. 2019;11(8). pii: E1808. doi: 10.3390/nu11081808.

Ancelin ML, Carrière I, Artero S, Maller J, Meslin C, Ritchie K, Ryan J, Chaudieu I. Lifetime major depression and grey-matter volume. J Psychiatry Neurosci. 2019;44(1):45-53

André P, Samieri C, Buisson C, Dartigues JF, Helmer C, Laugerette F, Féart C. Lipopolysaccharide-Binding Protein, Soluble CD14, and the Long-Term Risk of Alzheimer’s Disease: A Nested Case-Control Pilot Study of Older Community Dwellers from the Three-City Cohort. J Alzheimers Dis. 2019;71(3):751-761.

Arnould L, Seydou A, Gabrielle PH, Guenancia C, Tzourio C, Bourredjem A, El Alami Y, Daien V, Binquet C, Bron AM, Creuzot-Garcher C. Subfoveal Choroidal Thickness, Cardiovascular History, and Risk Factors in the Elderly: The Montrachet Study. Invest Ophthalmol Vis Sci. 2019;60(7):2431-2437

Baker E, Sims R, Leonenko G, Frizzati A, Harwood JC, Grozeva D; GERAD/PERADES; CHARGE; ADGC; EADI; IGAP consortia, Morgan K, Passmore P, Holmes C, Powell J, Brayne C, Gill M, Mead S, Bossù P, Spalletta G, Goate AM, Cruchaga C, Maier W, Heun R, Jessen F, Peters O, Dichgans M, FröLich L, Ramirez A, Jones L, Hardy J, Ivanov D, Hill M, Holmans P, Allen ND, Morgan BP, Seshadri S, Schellenberg GD, Amouyel P, Williams J, Escott-Price V. Gene-based analysis in HRC imputed genome wide association data identifies three novel genes for Alzheimer’s disease. PLoS One. 2019;14(7):e0218111. eCollection 2019

Blanc J, Seydou A, Ben Ghezala I, Deschasse C, Meillon C, Bron AM, Binquet C, Creuzot-Garcher C. Vitreomacular Interface Abnormalities and Glaucoma in an Elderly Population (The MONTRACHET Study). Invest Ophthalmol Vis Sci. 2019;60(6):1996-2002.

Chauhan G, Adams HHH, Satizabal CL, Bis JC, Teumer A, Sargurupremraj M, Hofer E, Trompet S, Hilal S, Smith AV, Jian X, Malik R, Traylor M, Pulit SL, Amouyel P, Mazoyer B, Zhu YC, Kaffashian S, Schilling S, Beecham GW, Montine TJ, Schellenberg GD, Kjartansson O, Guðnason V, Knopman DS, Griswold ME, Windham BG, Gottesman RF, Mosley TH, Schmidt R, Saba Y, Schmidt H, Takeuchi F, Yamaguchi S, Nabika T, Kato N, Rajan KB, Aggarwal NT, De Jager PL, Evans DA, Psaty BM, Rotter JI, Rice K, Lopez OL, Liao J, Chen C, Cheng CY, Wong TY, Ikram MK, van der Lee SJ, Amin N, Chouraki V, DeStefano AL, Aparicio HJ, Romero JR, Maillard P, DeCarli C, Wardlaw JM, Hernández MDCV, Luciano M, Liewald D, Deary IJ, Starr JM, Bastin ME, Muñoz Maniega S, Slagboom PE, Beekman M, Deelen J, Uh HW, Lemmens R, Brodaty H, Wright MJ, Ames D, Boncoraglio GB, Hopewell JC, Beecham AH, Blanton SH, Wright CB, Sacco RL, Wen W, Thalamuthu A, Armstrong NJ, Chong E, Schofield PR, Kwok JB, van der Grond J, Stott DJ, Ford I, Jukema JW, Vernooij MW, Hofman A, Uitterlinden AG, van der Lugt A, Wittfeld K, Grabe HJ, Hosten N, von Sarnowski B, Völker U, Levi C, Jimenez-Conde J, Sharma P, Sudlow CLM, Rosand J, Woo D, Cole JW, Meschia JF, Slowik A, Thijs V, Lindgren A, Melander O, Grewal RP, Rundek T, Rexrode K, Rothwell PM, Arnett DK, Jern C, Johnson JA, Benavente OR, Wasssertheil-Smoller S, Lee JM, Wong Q, Mitchell BD, Rich SS, McArdle PF, Geerlings MI, van der Graaf Y, de Bakker PIW, Asselbergs FW, Srikanth V, Thomson R, McWhirter R, Moran C, Callisaya M, Phan T, Rutten-Jacobs LCA, Bevan S, Tzourio C, Mather KA, Sachdev PS, van Duijn CM, Worrall BB, Dichgans M, Kittner SJ, Markus HS, Ikram MA, Fornage M, Launer LJ, Seshadri S, Longstreth WT Jr, Debette S; Stroke Genetics Network (SiGN), the International Stroke Genetics Consortium (ISGC), METASTROKE, Alzheimer’s Disease Genetics Consortium (ADGC), and the Neurology Working Group of the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium. Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting. Neurology. 2019 Jan 29; 92(5): e486–e503

Chen Z, Chen JA, Shatunov A, Jones AR, Kravitz SN, Huang AY, Lawrence L, Lowe JK, Lewis CM, Payan CAM, Lieb W, Franke A, Deloukas P, Amouyel P, Tzourio C, Dartigues JF; NNIPPS and BBBIPPS Study Groups, Ludolph A, Bensimon G, Leigh PN, Bronstein JM, Coppola G, Geschwind DH, Al-Chalabi A. Genome-wide survey of copy number variants finds MAPT duplications in progressive supranuclear palsy. Mov Disord. 2019;34(7):1049-1059. Epub 2019 May 6

Chung J, Marini S, Pera J, Norrving B, Jimenez-Conde J, Roquer J, Fernandez-Cadenas I, Tirschwell DL, Selim M, Brown DL, Silliman SL, Worrall BB, Meschia JF, Demel S, Greenberg SM, Slowik A, Lindgren A, Schmidt R, Traylor M, Sargurupremraj M, Tiedt S, Malik R, Debette S, Dichgans M, Langefeld CD, Woo D, Rosand J, Anderson CD. Genome-wide association study of cerebral small vessel disease reveals established and novel loci. Brain. 2019 Oct 1;142(10):3176-3189

Colijn JM, den Hollander AI, Demirkan A, Cougnard-Grégoire A, Verzijden T, Kersten E, Meester-Smoor MA, Merle BMJ, Papageorgiou G, Ahmad S, Mulder MT, Costa MA, Benlian P, Bertelsen G, Bron AM, Claes B, Creuzot-Garcher C, Erke MG, Fauser S, Foster PJ, Hammond CJ, Hense HW, Hoyng CB, Khawaja AP, Korobelnik JF, Piermarocchi S, Segato T, Silva R, Souied EH, Williams KM, van Duijn CM, Delcourt C, Klaver CCW; European Eye Epidemiology Consortium; EYE-RISK Consortium. Increased High-Density Lipoprotein Levels Associated with Age-Related Macular Degeneration: Evidence from the EYE-RISK and European Eye Epidemiology Consortia. Ophthalmology. 2019;126(3):393-406. Epub 2018 Oct 10.

Cosh S, Carrière I, Daien V, Tzourio C, Delcourt C, Helmer C. Sensory loss and suicide ideation in older adults: findings from the Three-City cohort study. Int Psychogeriatr. 2019;31(1):139-145. Epub 2018 May 25.

Cosh S, Carriere I, Nael V, Tzourio C, Delcourt C, Helmer C; Sense-Cog Consortium. The association of vision loss and dimensions of depression over 12 years in older adults: Findings from the Three City study. J Affect Disord. 2019 Jan 15;243:477-484. doi: 10.1016/j.jad.2018.09.071. Epub 2018 Sep 22

Cyprien F, Courtet P, Maller J, Meslin C, Ritchie K, Ancelin ML, Artero S. Increased Serum C-reactive Protein and Corpus Callosum Alterations in Older Adults. Aging Dis. 2019;10(2):463-469. eCollection 2019 Apr

Debette S, Schilling S, Duperron MG, Larsson SC, Markus HS. Clinical Significance of Magnetic Resonance Imaging Markers of Vascular Brain Injury: A Systematic Review and Meta-analysis. JAMA Neurol. 2019;76(1):81-94

Duperron MG, Tzourio C, Schilling S, Zhu YC, Soumaré A, Mazoyer B, Debette S. High dilated perivascular space burden: a new MRI marker for risk of intracerebral hemorrhage. Neurobiol Aging. 2019;84:158-165. Epub 2019 Sep 10

1Fretts AM, Imamura F, Marklund M, Micha R, Wu JHY, Murphy RA, Chien KL, McKnight B, Tintle N, Forouhi NG, Qureshi WT, Virtanen JK, Wong K, Wood AC, Lankinen M, Rajaobelina K, Harris TB, Djoussé L, Harris B, Wareham NJ, Steffen LM, Laakso M, Veenstra J, Samieri C, Brouwer IA, Yu CI, Koulman A, Steffen BT, Helmer C, Sotoodehnia N, Siscovick D, Gudnason V; InterAct Consortium, Wagenknecht L, Voutilainen S, Tsai MY, Uusitupa M, Kalsbeek A, Berr C, Mozaffarian D, Lemaitre RN. Associations of circulating very-long-chain saturated fatty acids and incident type 2 diabetes: a pooled analysis of prospective cohort studies. Am J Clin Nutr. 2019;109(4):1216-1223

Frison E, Dufouil C, Helmer C, Berr C, Auriacombe S, Chêne G. Diabetes-Associated Dementia Risk and Competing Risk of Death in the Three-City Study. J Alzheimers Dis. 2019;71(4):1339-1350

Galvin A, Helmer C, Coureau G, Amadeo B, Rainfray M, Soubeyran P, Dartigues JF, Pérès K, Bellera C, Delva F, Mathoulin-Pélissier S. Determinants of functional decline in older adults experiencing cancer (the INCAPAC study). J Geriatr Oncol. 2019 Mar 20. pii: S1879-4068(18)30400-4. doi: 10.1016/j.jgo.2019.03.006. 

Gattoussi S, Cougnard-Grégoire A, Korobelnik JF, Rougier MB, Delyfer MN, Schweitzer C, Le Goff M, Merle BMJ, Dartigues JF, Delcourt C. CHOROIDAL THICKNESS, VASCULAR FACTORS, AND AGE-RELATED MACULAR DEGENERATION: The ALIENOR Study. Retina. 2019 Jan;39(1):34-43

Gattoussi S, Buitendijk GHS, Peto T, Leung I, Schmitz-Valckenberg S, Oishi A, Wolf S, Deák G, Delcourt C, Klaver CCW, Korobelnik JF; European Eye Epidemiology (E3) consortium. The European Eye Epidemiology spectral-domain optical coherence tomography classification of macular diseases for epidemiological studies. Acta Ophthalmol. 2019;97(4):364-371. Epub 2018 Sep 22.

Giri A, Hellwege JN, Keaton JM, Park J, Qiu C, Warren HR, Torstenson ES, Kovesdy CP, Sun YV, Wilson OD, Robinson-Cohen C, Roumie CL, Chung CP, Birdwell KA, Damrauer SM, DuVall SL, Klarin D, Cho K, Wang Y, Evangelou E, Cabrera CP, Wain LV, Shrestha R, Mautz BS, Akwo EA, Sargurupremraj M, Debette S, Boehnke M, Scott LJ, Luan J, Zhao JH, Willems SM, Thériault S, Shah N, Oldmeadow C, Almgren P, Li-Gao R, Verweij N, Boutin TS, Mangino M, Ntalla I, Feofanova E, Surendran P, Cook JP, Karthikeyan S, Lahrouchi N, Liu C, Sepúlveda N, Richardson TG, Kraja A, Amouyel P, Farrall M, Poulter NR; Understanding Society Scientific Group; International Consortium for Blood Pressure; Blood Pressure-International Consortium of Exome Chip Studies, Laakso M, Zeggini E, Sever P, Scott RA, Langenberg C, Wareham NJ, Conen D, Palmer CNA, Attia J, Chasman DI, Ridker PM, Melander O, Mook-Kanamori DO, Harst PV, Cucca F, Schlessinger D, Hayward C, Spector TD, Jarvelin MR, Hennig BJ, Timpson NJ, Wei WQ, Smith JC, Xu Y, Matheny ME, Siew EE, Lindgren C, Herzig KH, Dedoussis G, Denny JC, Psaty BM, Howson JMM, Munroe PB, Newton-Cheh C, Caulfield MJ, Elliott P, Gaziano JM, Concato J, Wilson PWF, Tsao PS, Velez Edwards DR, Susztak K; Million Veteran Program, O’Donnell CJ, Hung AM, Edwards TL. Trans-ethnic association study of blood pressure determinants in over 750,000 individuals. Nat Genet. 2019;51(1):51-62. Epub 2018 Dec 21

Grasset L, Pérès K, Joly P, Sabathé C, Foubert-Samier A, Dartigues JF, Helmer C. Secular trends of mortality and dementia-free life expectancy over a 10-year period in France. Eur J Epidemiol. 2019;34(2):115-123. Epub 2019 Jan 16

Kunkle BW, Grenier-Boley B, Sims R, Bis JC, Damotte V, Naj AC, Boland A, Vronskaya M, van der Lee SJ, Amlie-Wolf A, Bellenguez C, Frizatti A, Chouraki V, Martin ER, Sleegers K, Badarinarayan N, Jakobsdottir J, Hamilton-Nelson KL, Moreno-Grau S, Olaso R, Raybould R, Chen Y, Kuzma AB, Hiltunen M, Morgan T, Ahmad S, Vardarajan BN, Epelbaum J, Hoffmann P, Boada M, Beecham GW, Garnier JG, Harold D, Fitzpatrick AL, Valladares O, Moutet ML, Gerrish A, Smith AV, Qu L, Bacq D, Denning N, Jian X, Zhao Y, Del Zompo M, Fox NC, Choi SH, Mateo I, Hughes JT, Adams HH, Malamon J, Sanchez-Garcia F, Patel Y, Brody JA, Dombroski BA, Naranjo MCD, Daniilidou M, Eiriksdottir G, Mukherjee S, Wallon D, Uphill J, Aspelund T, Cantwell LB, Garzia F, Galimberti D, Hofer E, Butkiewicz M, Fin B, Scarpini E, Sarnowski C, Bush WS, Meslage S, Kornhuber J, White CC, Song Y, Barber RC, Engelborghs S, Sordon S, Voijnovic D, Adams PM, Vandenberghe R, Mayhaus M, Cupples LA, Albert MS, De Deyn PP, Gu W, Himali JJ, Beekly D, Squassina A, Hartmann AM, Orellana A, Blacker D, Rodriguez-Rodriguez E, Lovestone S, Garcia ME, Doody RS, Munoz-Fernadez C, Sussams R, Lin H, Fairchild TJ, Benito YA, Holmes C, Karamujić-Čomić H, Frosch MP, Thonberg H, Maier W, Roschupkin G, Ghetti B, Giedraitis V, Kawalia A, Li S, Huebinger RM, Kilander L, Moebus S, Hernández I, Kamboh MI, Brundin R, Turton J, Yang Q, Katz MJ, Concari L, Lord J, Beiser AS, Keene CD, Helisalmi S, Kloszewska I, Kukull WA, Koivisto AM, Lynch A, Tarraga L, Larson EB, Haapasalo A, Lawlor B, Mosley TH, Lipton RB, Solfrizzi V, Gill M, Longstreth WT Jr, Montine TJ, Frisardi V, Diez-Fairen M, Rivadeneira F, Petersen RC, Deramecourt V, Alvarez I, Salani F, Ciaramella A, Boerwinkle E, Reiman EM, Fievet N, Rotter JI, Reisch JS, Hanon O, Cupidi C, Andre Uitterlinden AG, Royall DR, Dufouil C, Maletta RG, de Rojas I, Sano M, Brice A, Cecchetti R, George-Hyslop PS, Ritchie K, Tsolaki M, Tsuang DW, Dubois B, Craig D, Wu CK, Soininen H, Avramidou D, Albin RL, Fratiglioni L, Germanou A, Apostolova LG, Keller L, Koutroumani M, Arnold SE, Panza F, Gkatzima O, Asthana S, Hannequin D, Whitehead P, Atwood CS, Caffarra P, Hampel H, Quintela I, Carracedo Á, Lannfelt L, Rubinsztein DC, Barnes LL, Pasquier F, Frölich L, Barral S, McGuinness B, Beach TG, Johnston JA, Becker JT, Passmore P, Bigio EH, Schott JM, Bird TD, Warren JD, Boeve BF, Lupton MK, Bowen JD, Proitsi P, Boxer A, Powell JF, Burke JR, Kauwe JSK, Burns JM, Mancuso M, Buxbaum JD, Bonuccelli U, Cairns NJ, McQuillin A, Cao C, Livingston G, Carlson CS, Bass NJ, Carlsson CM, Hardy J, Carney RM, Bras J, Carrasquillo MM, Guerreiro R, Allen M, Chui HC, Fisher E, Masullo C, Crocco EA, DeCarli C, Bisceglio G, Dick M, Ma L, Duara R, Graff-Radford NR, Evans DA, Hodges A, Faber KM, Scherer M, Fallon KB, Riemenschneider M, Fardo DW, Heun R, Farlow MR, Kölsch H, Ferris S, Leber M, Foroud TM, Heuser I, Galasko DR, Giegling I, Gearing M, Hüll M, Geschwind DH, Gilbert JR, Morris J, Green RC, Mayo K, Growdon JH, Feulner T, Hamilton RL, Harrell LE, Drichel D, Honig LS, Cushion TD, Huentelman MJ, Hollingworth P, Hulette CM, Hyman BT, Marshall R, Jarvik GP, Meggy A, Abner E, Menzies GE, Jin LW, Leonenko G, Real LM, Jun GR, Baldwin CT, Grozeva D, Karydas A, Russo G, Kaye JA, Kim R, Jessen F, Kowall NW, Vellas B, Kramer JH, Vardy E, LaFerla FM, Jöckel KH, Lah JJ, Dichgans M, Leverenz JB, Mann D, Levey AI, Pickering-Brown S, Lieberman AP, Klopp N, Lunetta KL, Wichmann HE, Lyketsos CG, Morgan K, Marson DC, Brown K, Martiniuk F, Medway C, Mash DC, Nöthen MM, Masliah E, Hooper NM, McCormick WC, Daniele A, McCurry SM, Bayer A, McDavid AN, Gallacher J, McKee AC, van den Bussche H, Mesulam M, Brayne C, Miller BL, Riedel-Heller S, Miller CA, Miller JW, Al-Chalabi A, Morris JC, Shaw CE, Myers AJ, Wiltfang J, O’Bryant S, Olichney JM, Alvarez V, Parisi JE, Singleton AB, Paulson HL, Collinge J, Perry WR, Mead S, Peskind E, Cribbs DH, Rossor M, Pierce A, Ryan NS, Poon WW, Nacmias B, Potter H, Sorbi S, Quinn JF, Sacchinelli E, Raj A, Spalletta G, Raskind M, Caltagirone C, Bossù P, Orfei MD, Reisberg B, Clarke R, Reitz C, Smith AD, Ringman JM, Warden D, Roberson ED, Wilcock G, Rogaeva E, Bruni AC, Rosen HJ, Gallo M, Rosenberg RN, Ben-Shlomo Y, Sager MA, Mecocci P, Saykin AJ, Pastor P, Cuccaro ML, Vance JM, Schneider JA, Schneider LS, Slifer S, Seeley WW, Smith AG, Sonnen JA, Spina S, Stern RA, Swerdlow RH, Tang M, Tanzi RE, Trojanowski JQ, Troncoso JC, Van Deerlin VM, Van Eldik LJ, Vinters HV, Vonsattel JP, Weintraub S, Welsh-Bohmer KA, Wilhelmsen KC, Williamson J, Wingo TS, Woltjer RL, Wright CB, Yu CE, Yu L, Saba Y; Alzheimer Disease Genetics Consortium (ADGC),; European Alzheimer’s Disease Initiative (EADI),; Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium (CHARGE),; Genetic and Environmental Risk in AD/Defining Genetic, Polygenic and Environmental Risk for Alzheimer’s Disease Consortium (GERAD/PERADES),, Pilotto A, Bullido MJ, Peters O, Crane PK, Bennett D, Bosco P, Coto E, Boccardi V, De Jager PL, Lleo A, Warner N, Lopez OL, Ingelsson M, Deloukas P, Cruchaga C, Graff C, Gwilliam R, Fornage M, Goate AM, Sanchez-Juan P, Kehoe PG, Amin N, Ertekin-Taner N, Berr C, Debette S, Love S, Launer LJ, Younkin SG, Dartigues JF, Corcoran C, Ikram MA, Dickson DW, Nicolas G, Campion D, Tschanz J, Schmidt H, Hakonarson H, Clarimon J, Munger R, Schmidt R, Farrer LA, Van Broeckhoven C, C O’Donovan M, DeStefano AL, Jones L, Haines JL, Deleuze JF, Owen MJ, Gudnason V, Mayeux R, Escott-Price V, Psaty BM, Ramirez A, Wang LS, Ruiz A, van Duijn CM, Holmans PA, Seshadri S, Williams J, Amouyel P, Schellenberg GD, Lambert JC, Pericak-Vance MA. Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing. Nat Genet. 2019;51(3):414-430. Epub 2019 Feb 28

Larsson SC, Traylor M, Burgess S, Boncoraglio GB, Jern C, Michaëlsson K, Markus HS; MEGASTROKE project of the International Stroke Genetics Consortium. Serum magnesium and calcium levels in relation to ischemic stroke: Mendelian randomization study. Neurology. 2019 26;92(9):e944-e950. Epub 2019 Jan 25

Letellier N, Carrière I, Gutierrez LA, Gabelle A, Dartigues JF, Dufouil C, Helmer C, Cadot E, Berr C. Influence of activity space on the association between neighborhood characteristics and dementia risk: results from the 3-City study cohort. BMC Geriatr. 2019;19(1):4. doi: 10.1186/s12877-018-1017-7

Lipnicki DM, Makkar SR, Crawford JD, Thalamuthu A, Kochan NA, Lima-Costa MF, Castro-Costa E, Ferri CP, Brayne C, Stephan B, Llibre-Rodriguez JJ, Llibre-Guerra JJ, Valhuerdi-Cepero AJ, Lipton RB, Katz MJ, Derby CA, Ritchie K, Ancelin ML, Carrière I, Scarmeas N, Yannakoulia M, Hadjigeorgiou GM, Lam L, Chan WC, Fung A, Guaita A, Vaccaro R, Davin A, Kim KW, Han JW, Suh SW, Riedel-Heller SG, Roehr S, Pabst A, van Boxtel M, Köhler S, Deckers K, Ganguli M, Jacobsen EP, Hughes TF, Anstey KJ, Cherbuin N, Haan MN, Aiello AE, Dang K, Kumagai S, Chen T, Narazaki K, Ng TP, Gao Q, Nyunt MSZ, Scazufca M, Brodaty H, Numbers K, Trollor JN, Meguro K, Yamaguchi S, Ishii H, Lobo A, Lopez-Anton R, Santabárbara J, Leung Y, Lo JW, Popovic G, Sachdev PS; for Cohort Studies of Memory in an International Consortium (COSMIC). Determinants of cognitive performance and decline in 20 diverse ethno-regional groups: A COSMIC collaboration cohort study. PLoS Med. 2019;16(7):e1002853. eCollection 2019 Jul

Low DY, Lefèvre-Arbogast S, González-Domínguez R, Urpi-Sarda M, Micheau P, Petera M, Centeno D, Durand S, Pujos-Guillot E, Korosi A, Lucassen PJ, Aigner L, Proust-Lima C, Hejblum BP, Helmer C, Andres-Lacueva C, Thuret S, Samieri C, Manach C. Diet-Related Metabolites Associated with Cognitive Decline Revealed by Untargeted Metabolomics in a Prospective Cohort. Mol Nutr Food Res. 2019;63(18):e1900177. Epub 2019 Jul 9

Luo Q, Chen Q, Wang W, Desrivières S, Quinlan EB, Jia T, Macare C, Robert GH, Cui J, Guedj M, Palaniyappan L, Kherif F, Banaschewski T, Bokde ALW, Büchel C, Flor H, Frouin V, Garavan H, Gowland P, Heinz A, Ittermann B, Martinot JL, Artiges E, Paillère-Martinot ML, Nees F, Orfanos DP, Poustka L, Fröhner JH, Smolka MN, Walter H, Whelan R, Callicott JH, Mattay VS, Pausova Z, Dartigues JF, Tzourio C, Crivello F, Berman KF, Li F, Paus T, Weinberger DR, Murray RM, Schumann G, Feng J; IMAGEN consortium. Association of a Schizophrenia-Risk Nonsynonymous Variant With Putamen Volume in Adolescents: A Voxelwise and Genome-Wide Association Study. JAMA Psychiatry. 2019 Apr; 76(4): 435–445. Published online 2019 Jan 16. doi: 10.1001/jamapsychiatry.2018.4126

Ma Y, Jun GR, Zhang X, Chung J, Naj AC, Chen Y, Bellenguez C, Hamilton-Nelson K, Martin ER, Kunkle BW, Bis JC, Debette S, DeStefano AL, Fornage M, Nicolas G, van Duijn C, Bennett DA, De Jager PL, Mayeux R, Haines JL, Pericak-Vance MA, Seshadri S, Lambert JC, Schellenberg GD, Lunetta KL, Farrer LA; Alzheimer’s Disease Sequencing Project and Alzheimer’s Disease Exome Sequencing–France Project. Analysis of Whole-Exome Sequencing Data for Alzheimer Disease Stratified by APOE Genotype. JAMA Neurol. 2019 Jun 10;76(9):1099-1108. doi: 10.1001/jamaneurol.2019.1456

Marklund M, Wu JHY, Imamura F, Del Gobbo LC, Fretts A, de Goede J, Shi P, Tintle N, Wennberg M, Aslibekyan S, Chen TA, de Oliveira Otto MC, Hirakawa Y, Eriksen HH, Kröger J, Laguzzi F, Lankinen M, Murphy RA, Prem K, Samieri C, Virtanen J, Wood AC, Wong K, Yang WS, Zhou X, Baylin A, Boer JMA, Brouwer IA, Campos H, Chaves PHM, Chien KL, de Faire U, Djoussé L, Eiriksdottir G, El-Abbadi N, Forouhi NG, Michael Gaziano J, Geleijnse JM, Gigante B, Giles G, Guallar E, Gudnason V, Harris T, Harris WS, Helmer C, Hellenius ML, Hodge A, Hu FB, Jacques PF, Jansson JH, Kalsbeek A, Khaw KT, Koh WP, Laakso M, Leander K, Lin HJ, Lind L, Luben R, Luo J, McKnight B, Mursu J, Ninomiya T, Overvad K, Psaty BM, Rimm E, Schulze MB, Siscovick D, Skjelbo Nielsen M, Smith AV, Steffen BT, Steffen L, Sun Q, Sundström J, Tsai MY, Tunstall-Pedoe H, Uusitupa MIJ, van Dam RM, Veenstra J, Monique Verschuren WM, Wareham N, Willett W, Woodward M, Yuan JM, Micha R, Lemaitre RN, Mozaffarian D, Risérus U; Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Fatty Acids and Outcomes Research Consortium (FORCE).Biomarkers of Dietary Omega-6 Fatty Acids and Incident Cardiovascular Disease and Mortality. Circulation. 2019;139(21):2422-2436.

Merle BMJ, Colijn JM, Cougnard-Grégoire A, de Koning-Backus APM, Delyfer MN, Kiefte-de Jong JC, Meester-Smoor M, Féart C, Verzijden T, Samieri C, Franco OH, Korobelnik JF, Klaver CCW, Delcourt C; EYE-RISK Consortium. Mediterranean Diet and Incidence of Advanced Age-Related Macular Degeneration: The EYE-RISK Consortium. Ophthalmology. 2019;126(3):381-390. Epub 2018 Aug 13.

Mishra A, Chauhan G, Violleau MH, Vojinovic D, Jian X, Bis JC, Li S, Saba Y, Grenier-Boley B, Yang Q, Bartz TM, Hofer E, Soumaré A, Peng F, Duperron MG, Foglio M, Mosley TH, Schmidt R, Psaty BM, Launer LJ, Boerwinkle E, Zhu Y, Mazoyer B, Lathrop M, Bellenguez C, Van Duijn CM, Ikram MA, Schmidt H, Longstreth WT, Fornage M, Seshadri S, Joutel A, Tzourio C, Debette S. Association of variants in HTRA1 and NOTCH3 with MRI-defined extremes of cerebral small vessel disease in older subjects. Brain. 2019;142(4):1009-1023.

Naël V, Pérès K, Dartigues JF, Letenneur L, Amieva H, Arleo A, Scherlen AC, Tzourio C, Berr C, Carrière I, Delcourt C, Helmer C; Sense-Cog consortium. Vision loss and 12-year risk of dementia in older adults: the 3C cohort study. Eur J Epidemiol. 2019;34(2):141-152. Epub 2019 Jan 4.

Naël V, Moreau G, Monfermé S, Cougnard-Grégoire A, Scherlen AC, Arleo A, Korobelnik JF, Delcourt C, Helmer C. Prevalence and Associated Factors of Uncorrected Refractive Error in Older Adults in a Population-Based Study in France. JAMA Ophthalmol. 2019;137(1):3-11

NCD Risk Factor Collaboration (NCD-RisC). Rising rural body-mass index is the main driver of the global obesity epidemic in adults. Nature. 2019; 569(7755):260-264. Epub 2019 May 8

Ngabirano L, Samieri C, Feart C, Gabelle A, Artero S, Duflos C, Berr C, Mura T. Intake of Meat, Fish, Fruits, and Vegetables and Long-Term Risk of Dementia and Alzheimer’s Disease. J Alzheimers Dis. 2019;68(2):711-722. doi: 10.3233/JAD-180919

Norton J, Carrière I, Pérès K, Gabelle A, Berr C, Ritchie K, Ancelin ML. Sex-specific depressive symptoms as markers of pre-Alzheimer dementia: findings from the Three-City cohort study. Transl Psychiatry. 2019;9(1):291.

Ouvrard C, Meillon C, Dartigues JF, Tabue Teguo M, Avila-Funes JA, Amieva H. Psychosocioeconomic Precariousness and Frailty: The Respective Contribution in Predicting Mortality. J Frailty Aging. 2019;8(1):42-47.

Péquignot R, Dufouil C, Pérès K, Artero S, Tzourio C, Empana JP. Depression Increases the Risk of Death Independently From Vascular Events in Elderly Individuals: The Three-City Study. J Am Geriatr Soc. 2019;67(3):546-552. Epub 2019 Jan 17.

Pilleron S, Weber D, Pérès K, Colpo M, Gomez-Cabrero D, Stuetz W, Dartigues JF, Ferrucci L, Bandinelli S, Garcia-Garcia FJ, Grune T, Féart C; FRAILOMIC initiative. Patterns of circulating fat-soluble vitamins and carotenoids and risk of frailty in four European cohorts of older adults. Eur J Nutr. 2019; 58(1):379-389. Epub 2018 Jan 27

Planche V, Coupé P, Helmer C, Le Goff M, Amieva H, Tison F, Dartigues JF, Catheline G. Evolution of brain atrophy subtypes during aging predicts long-term cognitive decline and future Alzheimer’s clinical syndrome. Neurobiol Aging. 2019;79:22-29. Epub 2019 Mar 22.

Rhodes CJ, Batai K, Bleda M, Haimel M, Southgate L, Germain M, Pauciulo MW, Hadinnapola C, Aman J, Girerd B, Arora A, Knight J, Hanscombe KB, Karnes JH, Kaakinen M, Gall H, Ulrich A, Harbaum L, Cebola I, Ferrer J, Lutz K, Swietlik EM, Ahmad F, Amouyel P, Archer SL, Argula R, Austin ED, Badesch D, Bakshi S, Barnett C, Benza R, Bhatt N, Bogaard HJ, Burger CD, Chakinala M, Church C, Coghlan JG, Condliffe R, Corris PA, Danesino C, Debette S, Elliott CG, Elwing J, Eyries M, Fortin T, Franke A, Frantz RP, Frost A, Garcia JGN, Ghio S, Ghofrani HA, Gibbs JSR, Harley J, He H, Hill NS, Hirsch R, Houweling AC, Howard LS, Ivy D, Kiely DG, Klinger J, Kovacs G, Lahm T, Laudes M, Machado RD, MacKenzie Ross RV, Marsolo K, Martin LJ, Moledina S, Montani D, Nathan SD, Newnham M, Olschewski A, Olschewski H, Oudiz RJ, Ouwehand WH, Peacock AJ, Pepke-Zaba J, Rehman Z, Robbins I, Roden DM, Rosenzweig EB, Saydain G, Scelsi L, Schilz R, Seeger W, Shaffer CM, Simms RW, Simon M, Sitbon O, Suntharalingam J, Tang H, Tchourbanov AY, Thenappan T, Torres F, Toshner MR, Treacy CM, Vonk Noordegraaf A, Waisfisz Q, Walsworth AK, Walter RE, Wharton J, White RJ, Wilt J, Wort SJ, Yung D, Lawrie A, Humbert M, Soubrier F, Trégouët DA, Prokopenko I, Kittles R, Gräf S, Nichols WC, Trembath RC, Desai AA, Morrell NW, Wilkins MR; UK NIHR BioResource Rare Diseases Consortium; UK PAH Cohort Study Consortium; US PAH Biobank Consortium. Genetic determinants of risk in pulmonary arterial hypertension: international genome-wide association studies and meta-analysis. Lancet Respir Med. 2019;7(3):227-238. Epub 2018 Dec 5

Satizabal CL, Adams HHH, Hibar DP, White CC, Knol MJ, Stein JL, Scholz M, Sargurupremraj M, Jahanshad N, Roshchupkin GV, Smith AV, Bis JC, Jian X, Luciano M, Hofer E, Teumer A, van der Lee SJ, Yang J, Yanek LR, Lee TV, Li S, Hu Y, Koh JY, Eicher JD, Desrivières S, Arias-Vasquez A, Chauhan G, Athanasiu L, Rentería ME, Kim S, Hoehn D, Armstrong NJ, Chen Q, Holmes AJ, den Braber A, Kloszewska I, Andersson M, Espeseth T, Grimm O, Abramovic L, Alhusaini S, Milaneschi Y, Papmeyer M, Axelsson T, Ehrlich S, Roiz-Santiañez R, Kraemer B, Håberg AK, Jones HJ, Pike GB, Stein DJ, Stevens A, Bralten J, Vernooij MW, Harris TB, Filippi I, Witte AV, Guadalupe T, Wittfeld K, Mosley TH, Becker JT, Doan NT, Hagenaars SP, Saba Y, Cuellar-Partida G, Amin N, Hilal S, Nho K, Mirza-Schreiber N, Arfanakis K, Becker DM, Ames D, Goldman AL, Lee PH, Boomsma DI, Lovestone S, Giddaluru S, Le Hellard S, Mattheisen M, Bohlken MM, Kasperaviciute D, Schmaal L, Lawrie SM, Agartz I, Walton E, Tordesillas-Gutierrez D, Davies GE, Shin J, Ipser JC, Vinke LN, Hoogman M, Jia T, Burkhardt R, Klein M, Crivello F, Janowitz D, Carmichael O, Haukvik UK, Aribisala BS, Schmidt H, Strike LT, Cheng CY, Risacher SL, Pütz B, Fleischman DA, Assareh AA, Mattay VS, Buckner RL, Mecocci P, Dale AM, Cichon S, Boks MP, Matarin M, Penninx BWJH, Calhoun VD, Chakravarty MM, Marquand AF, Macare C, Kharabian Masouleh S, Oosterlaan J, Amouyel P, Hegenscheid K, Rotter JI, Schork AJ, Liewald DCM, de Zubicaray GI, Wong TY, Shen L, Sämann PG, Brodaty H, Roffman JL, de Geus EJC, Tsolaki M, Erk S, van Eijk KR, Cavalleri GL, van der Wee NJA, McIntosh AM, Gollub RL, Bulayeva KB, Bernard M, Richards JS, Himali JJ, Loeffler M, Rommelse N, Hoffmann W, Westlye LT, Valdés Hernández MC, Hansell NK, van Erp TGM, Wolf C, Kwok JBJ, Vellas B, Heinz A, Olde Loohuis LM, Delanty N, Ho BC, Ching CRK, Shumskaya E, Singh B, Hofman A, van der Meer D, Homuth G, Psaty BM, Bastin ME, Montgomery GW, Foroud TM, Reppermund S, Hottenga JJ, Simmons A, Meyer-Lindenberg A, Cahn W, Whelan CD, van Donkelaar MMJ, Yang Q, Hosten N, Green RC, Thalamuthu A, Mohnke S, Hulshoff Pol HE, Lin H, Jack CR Jr, Schofield PR, Mühleisen TW, Maillard P, Potkin SG, Wen W, Fletcher E, Toga AW, Gruber O, Huentelman M, Davey Smith G, Launer LJ, Nyberg L, Jönsson EG, Crespo-Facorro B, Koen N, Greve DN, Uitterlinden AG, Weinberger DR, Steen VM, Fedko IO, Groenewold NA, Niessen WJ, Toro R, Tzourio C, Longstreth WT Jr, Ikram MK, Smoller JW, van Tol MJ, Sussmann JE, Paus T, Lemaître H, Schroeter ML, Mazoyer B, Andreassen OA, Holsboer F, Depondt C, Veltman DJ, Turner JA, Pausova Z, Schumann G, van Rooij D, Djurovic S, Deary IJ, McMahon KL, Müller-Myhsok B, Brouwer RM, Soininen H, Pandolfo M, Wassink TH, Cheung JW, Wolfers T, Martinot JL, Zwiers MP, Nauck M, Melle I, Martin NG, Kanai R, Westman E, Kahn RS, Sisodiya SM, White T, Saremi A, van Bokhoven H, Brunner HG, Völzke H, Wright MJ, van ‘t Ent D, Nöthen MM, Ophoff RA, Buitelaar JK, Fernández G, Sachdev PS, Rietschel M, van Haren NEM, Fisher SE, Beiser AS, Francks C, Saykin AJ, Mather KA, Romanczuk-Seiferth N, Hartman CA, DeStefano AL, Heslenfeld DJ, Weiner MW, Walter H, Hoekstra PJ, Nyquist PA, Franke B, Bennett DA, Grabe HJ, Johnson AD, Chen C, van Duijn CM, Lopez OL, Fornage M, Wardlaw JM, Schmidt R, DeCarli C, De Jager PL, Villringer A, Debette S, Gudnason V, Medland SE, Shulman JM, Thompson PM, Seshadri S, Ikram MA. Genetic architecture of subcortical brain structures in 38,851 individuals. Nat Genet. 2019 Nov;51(11):1624-1636. Epub 2019 Oct 21

Silenou BC, Avalos M, Helmer C, Berr C, Pariente A, Jacqmin-Gadda H. Health administrative data enrichment using cohort information: Comparative evaluation of methods by simulation and application to real data. PLoS One. 2019;14(1):e0211118. eCollection 2019

Tully PJ, Helmer C, Peters R, Tzourio C. Exploiting Drug-Apolipoprotein E Gene Interactions in Hypertension to Preserve Cognitive Function: The 3-City Cohort Study. J Am Med Dir Assoc. 2019 Feb;20(2):188-194.e4. doi: 10.1016/j.jamda.2018.08.002. Epub 2018 Oct 3.

van der Lee SJ, Knol MJ, Chauhan G, Satizabal CL, Smith AV, Hofer E, Bis JC, Hibar DP, Hilal S, van den Akker EB, Arfanakis K, Bernard M, Yanek LR, Amin N, Crivello F, Cheung JW, Harris TB, Saba Y, Lopez OL, Li S, van der Grond J, Yu L, Paus T, Roshchupkin GV, Amouyel P, Jahanshad N, Taylor KD, Yang Q, Mathias RA, Boehringer S, Mazoyer B, Rice K, Cheng CY, Maillard P, van Heemst D, Wong TY, Niessen WJ, Beiser AS, Beekman M, Zhao W, Nyquist PA, Chen C, Launer LJ, Psaty BM, Ikram MK, Vernooij MW, Schmidt H, Pausova Z, Becker DM, De Jager PL, Thompson PM, van Duijn CM, Bennett DA, Slagboom PE, Schmidt R, Longstreth WT, Ikram MA, Seshadri S, Debette S, Gudnason V, Adams HHH, DeCarli C. A genome-wide association study identifies genetic loci associated with specific lobar brain volumes. Commun Biol. 2019;2:285. doi: 10.1038/s42003-019-0537-9. eCollection 2019

Walter S, Dufouil C, Gross AL, Jones RN, Mungas D, Filshtein TJ, Manly JJ, Arpawong TE, Glymour MM. Neuropsychological Test Performance and MRI Markers of Dementia Risk: Reducing Education Bias. Alzheimer Dis Assoc Disord. 2019;33(3):179-185

Wrigglesworth J, Ancelin ML, Ritchie K, Ryan J. Association between DNA methylation of the KITLG gene and cortisol levels under stress: a replication study. Stress. 2019;22(1):162-168. Epub 2018 Oct 9

Yang J, Trépo E, Nahon P, Cao Q, Moreno C, Letouzé E, Imbeaud S, Gustot T, Deviere J, Debette S, Amouyel P, Bioulac-Sage P, Calderaro J, Ganne-Carrié N, Laurent A, Blanc JF, Guyot E, Sutton A, Ziol M, Zucman-Rossi J, Nault JC. PNPLA3 and TM6SF2 variants as risk factors of hepatocellular carcinoma across various etiologies and severity of underlying liver diseases. Int J Cancer. 2019;144(3):533-544. Epub 2018 Nov 9

Acar İE, Lores-Motta L, Colijn JM, Meester-Smoor MA, Verzijden T, Cougnard-Gregoire A, Ajana S, Merle BMJ, de Breuk A, Heesterbeek TJ, van den Akker E, Daha MR, Claes B, Pauleikhoff D, Hense HW, van Duijn CM, Fauser S, Hoyng CB, Delcourt C, Klaver CCW, Galesloot TE, den Hollander AI; EYE-RISK Consortium. Integrating Metabolomics, Genomics, and Disease Pathways in Age-Related Macular Degeneration: The EYE-RISK Consortium. Ophthalmology. 2020;127(12):1693-1709. Epub 2020 Jun 14

Ancelin ML, Carriere I, Artero S, Maller JJ, Meslin C, Dupuy AM, Ritchie K, Ryan J, Chaudieu I. Structural brain changes with lifetime trauma and re-experiencing symptoms is 5-HTTLPR genotype-dependent. Eur J Psychotraumatol. 2020 Mar 4;11(1):1733247. doi: 10.1080/20008198.2020.1733247. eCollection 2020

Ancelin ML, Norton J, Canonico M, Scarabin PY, Ritchie K, Ryan J. Aromatase (CYP19A1) gene variants, sex steroid levels, and late-life depression. Depress Anxiety. 2020;37(2):146-155. doi: 10.1002/da.22974. Epub 2019 Nov 15

Armstrong NJ, Mather KA, Sargurupremraj M, Knol MJ, Malik R, Satizabal CL, Yanek LR, Wen W, Gudnason VG, Dueker ND, Elliott LT, Hofer E, Bis J, Jahanshad N, Li S, Logue MA, Luciano M, Scholz M, Smith AV, Trompet S, Vojinovic D, Xia R, Alfaro-Almagro F, Ames D, Amin N, Amouyel P, Beiser AS, Brodaty H, Deary IJ, Fennema-Notestine C, Gampawar PG, Gottesman R, Griffanti L, Jack CR Jr, Jenkinson M, Jiang J, Kral BG, Kwok JB, Lampe L, C M Liewald D, Maillard P, Marchini J, Bastin ME, Mazoyer B, Pirpamer L, Rafael Romero J, Roshchupkin GV, Schofield PR, Schroeter ML, Stott DJ, Thalamuthu A, Trollor J, Tzourio C, van der Grond J, Vernooij MW, Witte VA, Wright MJ, Yang Q, Morris Z, Siggurdsson S, Psaty B, Villringer A, Schmidt H, Haberg AK, van Duijn CM, Jukema JW, Dichgans M, Sacco RL, Wright CB, Kremen WS, Becker LC, Thompson PM, Mosley TH, Wardlaw JM, Ikram MA, Adams HHH, Seshadri S, Sachdev PS, Smith SM, Launer L, Longstreth W, DeCarli C, Schmidt R, Fornage M, Debette S, Nyquist PA. Common Genetic Variation Indicates Separate Causes for Periventricular and Deep White Matter Hyperintensities. Stroke. 2020;51(7):2111-2121. doi: 10.1161/STROKEAHA.119.027544. Epub 2020 Jun 10

Arnould L, De Lazzer A, Seydou A, Binquet C, Bron AM, Creuzot-Garcher C. Diagnostic ability of spectral-domain optical coherence tomography peripapillary retinal nerve fiber layer thickness to discriminate glaucoma patients from controls in an elderly population (The MONTRACHET study). Acta Ophthalmol. 2020 Dec;98(8):e1009-e1016. doi: 10.1111/aos.14448. Epub 2020 Apr 24.

Arnould L, Guillemin M, Seydou A, Gabrielle PH, Bourredjem A, Kawasaki R, Binquet C, Bron AM, Creuzot-Garcher C. Association between the retinal vascular network and retinal nerve fiber layer in the elderly: The Montrachet study. PLoS One. 2020;15(10):e0241055. eCollection 2020.

Bae JB, Lipnicki DM, Han JW, Sachdev PS, Kim TH, Kwak KP, Kim BJ, Kim SG, Kim JL, Moon SW, Park JH, Ryu SH, Youn JC, Lee DY, Lee DW, Lee SB, Lee JJ, Jhoo JH, Llibre-Rodriguez JJ, Llibre-Guerra JJ, Valhuerdi-Cepero AJ, Ritchie K, Ancelin ML, Carriere I, Skoog I, Najar J, Sterner TR, Scarmeas N, Yannakoulia M, Dardiotis E, Meguro K, Kasai M, Nakamura K, Riedel-Heller S, Roehr S, Pabst A, van Boxtel M, Köhler S, Ding D, Zhao Q, Liang X, Scazufca M, Lobo A, De-la-Cámara C, Lobo E, Kim KW; for Cohort Studies of Memory in an International Consortium (COSMIC). Does parity matter in women’s risk of dementia? A COSMIC collaboration cohort study. BMC Med. 2020 Aug 5;18(1):210. doi: 10.1186/s12916-020-01671-1

Biarnés M, Colijn JM, Sousa J, Ferraro LL, Garcia M, Verzijden T, Meester-Smoor MA, Delcourt C, Klaver CCW, den Hollander AI, Lengyel I, Peto T, Monés J; EYE-RISK Consortium. Genotype- and Phenotype-Based Subgroups in Geographic Atrophy Secondary to Age-Related Macular Degeneration: The EYE-RISK Consortium. Ophthalmol Retina. 2020 Dec;4(12):1129-1137. doi: 10.1016/j.oret.2020.04.014. Epub 2020 May 1

Canonico M, Artaud F, Tzourio C, Elbaz A. Association of Reproductive History With Motor Function and Disability in Aging Women. J Am Geriatr Soc. 2020;68(3):585-594. Epub 2019 Nov 25

Carles S, Carrière I, Reppermund S, Davin A, Guaita A, Vaccaro R, Ganguli M, Jacobsen EP, Beer JC, Riedel-Heller SG, Roehr S, Pabst A, Haan MN, Brodaty H, Kochan NA, Trollor JN, Kim KW, Han JW, Suh SW, Lobo A, la Camara C, Lobo E, Lipnicki DM, Sachdev PS, Ancelin ML, Ritchie K; for Cohort Studies of Memory in an International Consortium (COSMIC). A cross-national study of depression in preclinical dementia: A COSMIC collaboration study. Alzheimers Dement. 2020;16(11):1544-1552. Epub 2020 Sep 3

Cremer A, Boutouyrie P, Laurent S, Gosse P, Tzourio C. Orthostatic hypotension: a marker of blood pressure variability and arterial stiffness: a cross-sectional study on an elderly population: the 3-City study. J Hypertens. 2020 Jun;38(6):1103-1109. doi: 10.1097/HJH.0000000000002374

Delyfer MN, Legout P, Le Goff M, Blaizeau M, Rougier MB, Schweitzer C, Korobelnik JF, Delcourt C. Prevalence of epiretinal membranes in the ageing population using retinal colour images and SD-OCT: the Alienor Study. Acta Ophthalmol. 2020 Apr 17. doi: 10.1111/aos.14422. [Epub ahead of print]

Ding J, Davis-Plourde KL, Sedaghat S, Tully PJ, Wang W, Phillips C, Pase MP, Himali JJ, Gwen Windham B, Griswold M, Gottesman R, Mosley TH, White L, Guðnason V, Debette S, Beiser AS, Seshadri S, Ikram MA, Meirelles O, Tzourio C, Launer LJ. Antihypertensive medications and risk for incident dementia and Alzheimer’s disease: a meta-analysis of individual participant data from prospective cohort studies. Lancet Neurol. 2020 Jan;19(1):61-70. Epub 2019 Nov 6

Dupré C, Bongue B, Helmer C, Dartigues JF, Hupin D, Roche F, Berr C, Carrière I. Physical activity types and risk of dementia in community-dwelling older people: the Three-City cohort. BMC Geriatr. 2020;20(1):132.

Dutheil C, Le Goff M, Cougnard-Grégoire A, Gattoussi S, Korobelnik JF, Rougier MB, Schweitzer C, Delcourt C, Delyfer MN. Incidence and Risk Factors of Reticular Pseudodrusen Using Multimodal Imaging. JAMA Ophthalmol. 2020 May 1;138(5):467-477. doi: 10.1001/jamaophthalmol.2020.0266

Edde M, Theaud G, Rheault F, Dilharreguy B, Helmer C, Dartigues JF, Amieva H, Allard M, Descoteaux M, Catheline G. Free water: A marker of age-related modifications of the cingulum white matter and its association with cognitive decline. PLoS One. 2020 Nov 20;15(11):e0242696. doi: 10.1371/journal.pone.0242696. eCollection 2020.

Edde M, Dilharreguy B, Theaud G, Chanraud S, Helmer C, Dartigues JF, Amieva H, Allard M, Descoteaux M, Catheline G. Age-related change in episodic memory: role of functional and structural connectivity between the ventral posterior cingulate and the parietal cortex. Brain Struct Funct. 2020;225(7):2203-2218. doi: 10.1007/s00429-020-02121-7. Epub 2020 Jul 29.

Fransquet PD, Ritchie K, Januar V, Saffery R, Ancelin ML, Ryan J. Is Peripheral BDNF Promoter Methylation a Preclinical Biomarker of Dementia? J Alzheimers Dis. 2020;73(2):645-655. doi: 10.3233/JAD-190738

Gentreau M, Chuy V, Féart C, Samieri C, Ritchie K, Raymond M, Berticat C, Artero S. Refined carbohydrate-rich diet is associated with long-term risk of dementia and Alzheimer’s disease in apolipoprotein E ε4 allele carriers. Alzheimers Dement. 2020 Jul;16(7):1043-1053. doi: 10.1002/alz.12114. Epub 2020 Jun 7

Gentreau M, Raymond M, Chuy V, Samieri C, Féart C, Berticat C, Artero S. High Glycemic Load Is Associated with Cognitive Decline in Apolipoprotein E ε4 Allele Carriers. Nutrients. 2020;12(12):3619

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Imamura F, Fretts AM, Marklund M, Ardisson Korat AV, Yang WS, Lankinen M, Qureshi W, Helmer C, Chen TA, Virtanen JK, Wong K, Bassett JK, Murphy R, Tintle N, Yu CI, Brouwer IA, Chien KL, Chen YY, Wood AC, Del Gobbo LC, Djousse L, Geleijnse JM, Giles GG, de Goede J, Gudnason V, Harris WS, Hodge A, Hu F; InterAct Consortium, Koulman A, Laakso M, Lind L, Lin HJ, McKnight B, Rajaobelina K, Riserus U, Robinson JG, Samieri C, Senn M, Siscovick DS, Soedamah-Muthu SS, Sotoodehnia N, Sun Q, Tsai MY, Tuomainen TP, Uusitupa M, Wagenknecht LE, Wareham NJ, Wu JHY, Micha R, Lemaitre RN, Mozaffarian D, Forouhi NG. Fatty acids in the de novo lipogenesis pathway and incidence of type 2 diabetes: A pooled analysis of prospective cohort studies. PLoS Med. 2020;17(6):e1003102. doi: 10.1371/journal.pmed.1003102. eCollection 2020 Jun

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Laouali N, Brailly-Tabard S, Helmer C, Ancelin ML, Tzourio C, Elbaz A, Guiochon-Mantel A, Canonico M. Testosterone Level and Cause-Specific Mortality in Older Men without Metabolic Syndrome. Epidemiol Health. 2020 Jun 1:e2020036. doi: 10.4178/epih.e2020036. Online ahead of print

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Makkar SR, Lipnicki DM, Crawford JD, Kochan NA, Castro-Costa E, Lima-Costa MF, Diniz BS, Brayne C, Stephan B, Matthews F, Llibre-Rodriguez JJ, Llibre-Guerra JJ, Valhuerdi-Cepero AJ, Lipton RB, Katz MJ, Zammit A, Ritchie K, Carles S, Carriere I, Scarmeas N, Yannakoulia M, Kosmidis M, Lam L, Fung A, Chan WC, Guaita A, Vaccaro R, Davin A, Kim KW, Han JW, Suh SW, Riedel-Heller SG, Roehr S, Pabst A, Ganguli M, Hughes TF, Jacobsen EP, Anstey KJ, Cherbuin N, Haan MN, Aiello AE, Dang K, Kumagai S, Narazaki K, Chen S, Ng TP, Gao Q, Nyunt MSZ, Meguro K, Yamaguchi S, Ishii H, Lobo A, Lobo Escolar E, De la Cámara C, Brodaty H, Trollor JN, Leung Y, Lo JW, Sachdev P; for Cohort Studies of Memory in an International Consortium (COSMIC). Education and the moderating roles of age, sex, ethnicity and apolipoprotein epsilon 4 on the risk of cognitive impairment. Arch Gerontol Geriatr. 2020;91:104112. Epub 2020 Jul 13

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Nadal J, Deverdun J, de Champfleur NM, Carriere I, Creuzot-Garcher C, Delcourt C, Chiquet C, Kawasaki R, Villain M, Ritchie K, Le Bars E, Daien V. Retinal vascular fractal dimension and cerebral blood flow, a pilot study. Acta Ophthalmol. 2020;98(1):e63-e71. Epub 2019 Sep 23

Nadal L, Coupé P, Helmer C, Manjon JV, Amieva H, Tison F, Dartigues JF, Catheline G, Planche V. Differential annualized rates of hippocampal subfields atrophy in aging and future Alzheimer’s clinical syndrome. Neurobiol Aging. 2020;90:75-83. Epub 2020 Feb 1

Nadal L, Coupé P, Helmer C, Tison F, Dartigues JF, Catheline G, Planche V. Dynamique de l’atrophie des sous-champs hippocampiques dans le vieillissement et la maladie d’Alzheimer. Rev Neurol (Paris). 2020 Sep;176S:S2. doi: 10.1016/j.neurol.2020.01.054

NCD Risk Factor Collaboration (NCD-RisC). Repositioning of the global epicentre of non-optimal cholesterol. Nature. 2020 Jun;582(7810):73-77. doi: 10.1038/s41586-020-2338-1. Epub 2020 Jun 3

NCD Risk Factor Collaboration (NCD-RisC). National trends in total cholesterol obscure heterogeneous changes in HDL and non-HDL cholesterol and total-to-HDL cholesterol ratio: a pooled analysis of 458 population-based studies in Asian and Western countries. Int J Epidemiol. 2020;49(1):173-192. doi: 10.1093/ije/dyz099

Nilaweera D, Freak-Poli R, Ritchie K, Chaudieu I, Ancelin ML, Ryan J. The long-term consequences of trauma and posttraumatic stress disorder symptoms on later life cognitive function and dementia risk. Psychiatry Res. 2020 Dec;294:113506. doi: 10.1016/j.psychres.2020.113506. Epub 2020 Oct 11.

Olin JW, Di Narzo AF, d’Escamard V, Kadian-Dodov D, Cheng H, Georges A, King A, Thomas A, Barwari T, Michelis KC, Bouchareb R, Bander E, Anyanwu A, Stelzer P, Filsoufi F, Florman S, Civelek M, Debette S, Jeunemaitre X, Björkegren JLM, Mayr M, Bouatia-Naji N, Hao K, Kovacic JC. A plasma proteogenomic signature for fibromuscular dysplasia. Cardiovasc Res. 2020;116(1):63-77. doi: 10.1093/cvr/cvz219

Parker N, Vidal-Pineiro D, French L, Shin J, Adams HHH, Brodaty H, Cox SR, Deary IJ, Fjell AM, Frenzel S, Grabe H, Hosten N, Ikram MA, Jiang J, Knol MJ, Mazoyer B, Mishra A, Sachdev PS, Salum G, Satizabal CL, Schmidt H, Schmidt R, Seshadri S, Schumann G, Völzke H, Walhovd KB, Wen W, Wittfeld K, Yang Q, Debette S, Pausova Z, Paus T. Corticosteroids and Regional Variations in Thickness of the Human Cerebral Cortex across the Lifespan. Cereb Cortex. 2020;30(2):575-586.

Pellay H, Marmonier C, Samieri C, Feart C. Socio-Demographic Characteristics, Dietary, and Nutritional Intakes of French Elderly Community Dwellers According to Their Dairy Product Consumption: Data from the Three-City Cohort. Nutrients. 2020;12(11):3418.

Ruth Peters, Sevil Yasar, Craig S. Anderson, Shea Andrews, Riitta Antikainen, Hisatomi Arima, Nigel Beckett, Joanne C. Beer, Anne Suzanne Bertens, Andrew Booth, Martin van Boxtel, Carol Brayne, Henry Brodaty, Michelle C. Carlson, John Chalmers, Maria Corrada, Steven DeKosky, Carol Derby, Roger A. Dixon, Françoise Forette, Mary Ganguli, Willem A. van Gool, Antonio Guaita, Ann M. Hever, David B. Hogan, Carol Jagger, Mindy Katz, Claudia Kawas, Patrick G. Kehoe, Sirkka Keinanen-Kiukaanniemi, Rose Ann Kenny, Sebastian Köhler, Setor K. Kunutsor, Jari Laukkanen, Colleen Maxwell, G. Peggy McFall, Tessa van Middelaar, Eric P. Moll van Charante, Tze-Pin Ng, Jean Peters, Iris Rawtaer, Edo Richard, Kenneth Rockwood, Lina Rydén, Perminder S. Sachdev, Ingmar Skoog, Johan Skoog, Jan A. Staessen, Blossom C.M. Stephan, Sylvain Sebert, Lutgarde Thijs, Stella Trompet, Phillip J. Tully, Christophe Tzourio, Roberta Vaccaro, Eeva Vaaramo, Erin Walsh, Jane Warwick, Kaarin J. Anstey. Investigation of antihypertensive class, dementia, and cognitive decline: A meta-analysis. Neurology. 2020 Jan 21; 94(3): e267–e281

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Saddiki H, Fayosse A, Cognat E, Sabia S, Engelborghs S, Wallon D, Alexopoulos P, Blennow K, Zetterberg H, Parnetti L, Zerr I, Hermann P, Gabelle A, Boada M, Orellana A, de Rojas I, Lilamand M, Bjerke M, Van Broeckhoven C, Farotti L, Salvadori N, Diehl-Schmid J, Grimmer T, Hourregue C, Dugravot A, Nicolas G, Laplanche JL, Lehmann S, Bouaziz-Amar E; Alzheimer’s Disease Neuroimaging Initiative, Hugon J, Tzourio C, Singh-Manoux A, Paquet C, Dumurgier J. Age and the association between apolipoprotein E genotype and Alzheimer disease: A cerebrospinal fluid biomarker-based case-control study. PLoS Med. 2020;17(8):e1003289. doi: 10.1371/journal.pmed.1003289. eCollection 2020 Aug

Saint Pierre A, Giemza J, Alves I, Karakachoff M, Gaudin M, Amouyel P, Dartigues JF, Tzourio C, Monteil M, Galan P, Hercberg S, Mathieson I, Redon R, Génin E, Dina C. The genetic history of France. Eur J Hum Genet. 2020;28(7):853-865. doi: 10.1038/s41431-020-0584-1. Epub 2020 Feb 10

Samieri C, Rajendra Sonawane A, Lefèvre-Arbogast S, Helmer C, Grodstein F, Glass K. Using network science tools to identify novel diet patterns in prodromal dementia. Neurology. 2020 May 12;94(19):e2014-e2025.doi: 10.1212/WNL.0000000000009399

Sargurupremraj M, Suzuki H, Jian X, Sarnowski C, Evans TE, Bis JC, Eiriksdottir G, Sakaue S, Terzikhan N, Habes M, Zhao W, Armstrong NJ, Hofer E, Yanek LR, Hagenaars SP, Kumar RB, van den Akker EB, McWhirter RE, Trompet S, Mishra A, Saba Y, Satizabal CL, Beaudet G, Petit L, Tsuchida A, Zago L, Schilling S, Sigurdsson S, Gottesman RF, Lewis CE, Aggarwal NT, Lopez OL, Smith JA, Valdés Hernández MC, van der Grond J, Wright MJ, Knol MJ, Dörr M, Thomson RJ, Bordes C, Le Grand Q, Duperron MG, Smith AV, Knopman DS, Schreiner PJ, Evans DA, Rotter JI, Beiser AS, Maniega SM, Beekman M, Trollor J, Stott DJ, Vernooij MW, Wittfeld K, Niessen WJ, Soumaré A, Boerwinkle E, Sidney S, Turner ST, Davies G, Thalamuthu A, Völker U, van Buchem MA, Bryan RN, Dupuis J, Bastin ME, Ames D, Teumer A, Amouyel P, Kwok JB, Bülow R, Deary IJ, Schofield PR, Brodaty H, Jiang J, Tabara Y, Setoh K, Miyamoto S, Yoshida K, Nagata M, Kamatani Y, Matsuda F, Psaty BM, Bennett DA, De Jager PL, Mosley TH, Sachdev PS, Schmidt R, Warren HR, Evangelou E, Trégouët DA; International Network against Thrombosis (INVENT) Consortium; International Headache Genomics Consortium (IHGC), Ikram MA, Wen W, DeCarli C, Srikanth VK, Jukema JW, Slagboom EP, Kardia SLR, Okada Y, Mazoyer B, Wardlaw JM, Nyquist PA, Mather KA, Grabe HJ, Schmidt H, Van Duijn CM, Gudnason V, Longstreth WT Jr, Launer LJ, Lathrop M, Seshadri S, Tzourio C, Adams HH, Matthews PM, Fornage M, Debette S. Cerebral small vessel disease genomics and its implications across the lifespan. Nat Commun. 2020;11(1):6285

Schijven D, Stevelink R, McCormack M, van Rheenen W, Luykx JJ, Koeleman BPC, Veldink JH; Project MinE ALS GWAS Consortium; International League Against Epilepsy Consortium on Complex Epilepsies. Analysis of shared common genetic risk between amyotrophic lateral sclerosis and epilepsy. Neurobiol Aging. 2020 Aug;92:153.e1-153.e5. doi: 10.1016/j.neurobiolaging.2020.04.011. Epub 2020 Apr 18

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Tully PJ, Alpérovitch A, Soumaré A, Mazoyer B, Debette S, Tzourio C. Association Between Cerebral Small Vessel Disease With Antidepressant Use and Depression: 3C Dijon Magnetic Resonance Imaging Study. Stroke. 2020;51(2):402-408. Epub 2019 Dec 12

Thomas A, Baillet M, Proust-Lima C, Féart C, Foubert-Samier A, Helmer C, Catheline G, Samieri C. Blood polyunsaturated omega-3 fatty acids, brain atrophy, cognitive decline, and dementia risk. Alzheimers Dement. 2020 Oct 8. doi: 10.1002/alz.12195.

Tully PJ, Kurth T, Elbaz A, Tzourio C. Convergence of psychiatric symptoms and restless legs syndrome: A cross-sectional study in an elderly French population. J Psychosom Res. 2020;128:109884. Epub 2019 Nov 25

Phillip J. Tully, Yuichiro Yano, Lenore J. Launer, Kazuomi Kario, Michiaki Nagai, Simon P. Mooijaart, Jurgen A. H. R. Claassen, Simona Lattanzi, Andrew D. Vincent, Christophe Tzourio, the Variability in Blood Pressure and Brain Health Consortium. Association Between Blood Pressure Variability and Cerebral Small‐Vessel Disease: A Systematic Review and Meta‐Analysis. J Am Heart Assoc. 2020; 9(1): e013841. Published online 2019 Dec 24

Wolters FJ, Chibnik LB, Waziry R, Anderson R, Berr C, Beiser A, Bis JC, Blacker D, Bos D, Brayne C, Dartigues JF, Darweesh SKL, Davis-Plourde KL, de Wolf F, Debette S, Dufouil C, Fornage M, Goudsmit J, Grasset L, Gudnason V, Hadjichrysanthou C, Helmer C, Ikram MA, Ikram MK, Joas E, Kern S, Kuller LH, Launer L, Lopez OL, Matthews FE, McRae-McKee K, Meirelles O, Mosley TH Jr, Pase MP, Psaty BM, Satizabal CL, Seshadri S, Skoog I, Stephan BCM, Wetterberg H, Wong MM, Zettergren A, Hofman A. Twenty-seven-year time trends in dementia incidence in Europe and the United States: The Alzheimer Cohorts Consortium. Neurology. 2020;95(5):e519-e531. Epub 2020 Jul 1

Zamudio-Rodríguez A, Letenneur L, Féart C, Avila-Funes JA, Amieva H, Pérès K. The disability process: is there a place for frailty? Age Ageing. 2020;49(5):764-770

Ajana S, Cougnard-Grégoire A, Colijn JM, Merle BM, Verzijden T, de Jong PT, Hofman A, Vingerling JR, Hejblum BP, Korobelnik JF, Meester-Smoor MA, Ueffing M, Jacqmin-Gadda H, Klaver CC, Delcourt C; EYE-RISK Consortium. Predicting Progression to Advanced Age-Related Macular Degeneration from Clinical, Genetic, and Lifestyle Factors Using Machine Learning. Ophthalmology. 2021;128(4):587-597. Epub 2020 Sep 2

Ancelin ML, Carrière I, Artero S, Maller JJ, Meslin C, Dupuy AM, Ritchie K, Ryan J, Chaudieu I. Structural brain alterations in older adults exposed to early-life adversity. Psychoneuroendocrinology. 2021;129:105272. Epub 2021 May 15

Ancelin ML, Norton J, Ritchie K, Chaudieu I, Ryan J. Steroid 21-hydroxylase gene variants and late-life depression. BMC Res Notes. 2021;14(1):203

Ancelin ML, Norton J, Ritchie K, Chaudieu I, Ryan J. 11β-Hydroxylase (CYP11B1) gene variants and new-onset depression in later life. J Psychiatry Neurosci. 2021;46(1):E147-E153.

Ancelin ML, Norton J, Scali J, Ritchie K, Chaudieu I, Ryan J. A Prospective Study of Diurnal Cortisol and Incident Dementia in Community-Dwelling Older Adults. J Alzheimers Dis. 2021;82(3):899-904

André P, Pais de Barros JP, Mj Merle B, Samieri C, Helmer C, Delcourt C, Féart C. Mediterranean diet and prudent diet are both associated with low circulating esterified 3-hydroxy fatty acids, a proxy of LPS burden, among older adults. Am J Clin Nutr. 2021 May 24:nqab126. doi: 10.1093/ajcn/nqab126.

Arnould L, Guenancia C, Binquet C, Delcourt C, Chiquet C, Daien V, Cottin Y, Bron AM, Acar N, Creuzot-Garcher C. Retinal vascular network: Changes with aging and systemic vascular disease (cardiac and cerebral). J Fr Ophtalmol. 2021 Nov 23:S0181-5512(21)00521-0. doi: 10.1016/j.jfo.2021.09.004.

Baksh RA, Ritchie CW, Terrera GM, Norton J, Raymont V, Ritchie K. The association between anxiety disorders and hippocampal volume in older adults. Psychol Aging. 2021;36(2):288-297. doi: 10.1037/pag0000597. Epub 2021 Mar 4.

Bastard P, Gervais A, Le Voyer T, Rosain J, Philippot Q, Manry J, Michailidis E, Hoffmann HH, Eto S, Garcia-Prat M, Bizien L, Parra-Martínez A, Yang R, Haljasmägi L, Migaud M, Särekannu K, Maslovskaja J, de Prost N, Tandjaoui-Lambiotte Y, Luyt CE, Amador-Borrero B, Gaudet A, Poissy J, Morel P, Richard P, Cognasse F, Troya J, Trouillet-Assant S, Belot A, Saker K, Garçon P, Rivière JG, Lagier JC, Gentile S, Rosen LB, Shaw E, Morio T, Tanaka J, Dalmau D, Tharaux PL, Sene D, Stepanian A, Megarbane B, Triantafyllia V, Fekkar A, Heath JR, Franco JL, Anaya JM, Solé-Violán J, Imberti L, Biondi A, Bonfanti P, Castagnoli R, Delmonte OM, Zhang Y, Snow AL, Holland SM, Biggs C, Moncada-Vélez M, Arias AA, Lorenzo L, Boucherit S, Coulibaly B, Anglicheau D, Planas AM, Haerynck F, Duvlis S, Nussbaum RL, Ozcelik T, Keles S, Bousfiha AA, El Bakkouri J, Ramirez-Santana C, Paul S, Pan-Hammarström Q, Hammarström L, Dupont A, Kurolap A, Metz CN, Aiuti A, Casari G, Lampasona V, Ciceri F, Barreiros LA, Dominguez-Garrido E, Vidigal M, Zatz M, van de Beek D, Sahanic S, Tancevski I, Stepanovskyy Y, Boyarchuk O, Nukui Y, Tsumura M, Vidaur L, Tangye SG, Burrel S, Duffy D, Quintana-Murci L, Klocperk A, Kann NY, Shcherbina A, Lau YL, Leung D, Coulongeat M, Marlet J, Koning R, Reyes LF, Chauvineau-Grenier A, Venet F, Monneret G, Nussenzweig MC, Arrestier R, Boudhabhay I, Baris-Feldman H, Hagin D, Wauters J, Meyts I, Dyer AH, Kennelly SP, Bourke NM, Halwani R, Sharif-Askari NS, Dorgham K, Sallette J, Sedkaoui SM, AlKhater S, Rigo-Bonnin R, Morandeira F, Roussel L, Vinh DC, Ostrowski SR, Condino-Neto A, Prando C, Bonradenko A, Spaan AN, Gilardin L, Fellay J, Lyonnet S, Bilguvar K, Lifton RP, Mane S; HGID Lab; COVID Clinicians; COVID-STORM Clinicians; NIAID Immune Response to COVID Group; NH-COVAIR Study Group; Danish CHGE; Danish Blood Donor Study; St. James’s Hospital; SARS CoV2 Interest group; French COVID Cohort Study Group; Imagine COVID-Group; Milieu Intérieur Consortium; CoV-Contact Cohort; Amsterdam UMC Covid-19; Biobank Investigators; COVID Human Genetic Effort; CONSTANCES cohort; 3C-Dijon Study; Cerba Health-Care; Etablissement du Sang study group, Anderson MS, Boisson B, Béziat V, Zhang SY, Vandreakos E, Hermine O, Pujol A, Peterson P, Mogensen TH, Rowen L, Mond J, Debette S, de Lamballerie X, Duval X, Mentré F, Zins M, Soler-Palacin P, Colobran R, Gorochov G, Solanich X, Susen S, Martinez-Picado J, Raoult D, Vasse M, Gregersen PK, Piemonti L, Rodríguez-Gallego C, Notarangelo LD, Su HC, Kisand K, Okada S, Puel A, Jouanguy E, Rice CM, Tiberghien P, Zhang Q, Cobat A, Abel L, Casanova JL. Autoantibodies neutralizing type I IFNs are present in ~4% of uninfected individuals over 70 years old and account for ~20% of COVID-19 deaths. Sci Immunol. 2021;6(62):eabl4340.

Ben Ghezala I, Seydou A, Gabrielle PH, Bouche-Pillon J, Binquet C, Delcourt C, Daien V, Bron AM, Creuzot-Garcher C. Epidemiology of vitreomacular interface abnormalities usign macular spectral-domain optical coherence tomography in an elderly population (THE MONTRACHET STUDY). Retina. 2021;41(1):60-67. doi: 10.1097/IAE.0000000000002802

Ben-Hassen C, Helmer C, Berr C, Jacqmin-Gadda H. 5-Year dynamic prediction of dementia using repeated measures of cognitive tests and a dependency scale. Am J Epidemiol. 2021 Nov 9:kwab269. doi: 10.1093/aje/kwab269.

Ben Ghezala I, Seydou A, Gabrielle PH, Bouche-Pillon J, Binquet C, Delcourt C, Daien V, Bron AM, Creuzot-Garcher C. Epidemiology of vitreomacular interface abnormalties using macular spectral-domain optical coherence tomography in an elderly population (THE MONTRACHET STUDY). Retina. 2021;41(1):60-67. doi: 10.1097/IAE.0000000000002802

Caillot-Ranjeva S, Amieva H, Meillon C, Helmer C, Berr C, Bergua V. Similarities in cognitive abilities in older couples: a study of mutual influences. J Clin Exp Neuropsychol. 2021 Feb;43(1):78-90. doi: 10.1080/13803395.2021.1874882. Epub 2021 Feb 8

Caillot-Ranjeva S, Gourlain S, Amieva H, Helmer C, Bergua V. Study of mutual influence between trait anxiety and risk of depression among older couples facing cancer. J Geriatr Oncol. 2021;12(4):605-611. Epub 2020 Sep 29

Carles S, Taddé BO, Berr C, Helmer C, Jacqmin-Gadda H, Carrière I, Proust-Lima C. Dynamic reciprocal relationships between cognitive and functional declines along the Alzheimer’s disease continuum in the prospective COGICARE study. Alzheimers Res Ther. 2021;13(1):148. doi: 10.1186/s13195-021-00887-4.

Chambon C, Neyraud E, Sayd T, Bros P, Di Biagio R, Hyvrier F, Féart C, André P, Rodriguez-Artalejo F, Lopez-Garcia E, Garcia-Esquinas E, Gomez-Cabrero D, Proctor G, Morzel M. The salivary proteome reflects some traits of dietary habits in diabetic and non-diabetic older adults. Eur J Nutr. 2021;60(8):4331-4344. Epub 2021 May 26

Chemaly A, Arnould L, Seydou A, Gabrielle PH, Baudin F, Acar N, Creuzot-Garcher C. Plasma fatty acids and primary open-angle glaucoma in the elderly: the Montrachet population-based study. BMC Ophthalmol. 2021 Mar 23;21(1):146. doi: 10.1186/s12886-021-01910-w.

Colijn JM, Meester-Smoor M, Verzijden T, de Breuk A, Silva R, Merle BMJ, Cougnard-Grégoire A, Hoyng CB, Fauser S, Coolen A, Creuzot-Garcher C, Hense HW, Ueffing M, Delcourt C, den Hollander AI, Klaver CCW; EYE-RISK Consortium. Genetic Risk, Lifestyle, and Age-Related Macular Degeneration in Europe: The EYE-RISK Consortium. Ophthalmology. 2021;128(7):1039-1049. Epub 2020 Nov 28

Cosh S, Carriere I, Delcourt C, Helmer C, Consortium TS. A dimensional approach to understanding the relationship between self-reported hearing loss and depression over 12 years: the Three-City study. Aging Ment Health. 2021;25(5):954-961. Epub 2020 Mar 13

Chuy V, Gentreau M, Artero S, Berticat C, Rigalleau V, Pérès K, Helmer C, Samieri C, Féart C. Simple carbohydrate intake and higher risk for physical frailty over 15 years in community-dwelling older adults. J Gerontol A Biol Sci Med Sci. 2021 Aug 21:glab243.

Cyprien F, Berr C, Maller JJ, Meslin C, Gentreau M, Mura T, Gabelle A, Courtet P, Ritchie K, Ancelin ML, Artero S. Late-life cynical hostility is associated with white matter alterations and the risk of Alzheimer’s disease. Psychol Med. 2021 Apr 14:1-10. doi: 10.1017/S0033291721000416. 

Damotte V, van der Lee SJ, Chouraki V, Grenier-Boley B, Simino J, Adams H, Tosto G, White C, Terzikhan N, Cruchaga C, Knol MJ, Li S, Schraen S, Grove ML, Satizabal C, Amin N, Berr C, Younkin S; Alzheimer’s Disease Neuroimaging Initiative, Gottesman RF, Buée L, Beiser A, Knopman DS, Uitterlinden A, DeCarli C, Bressler J, DeStefano A, Dartigues JF, Yang Q, Boerwinkle E, Tzourio C, Fornage M, Ikram MA, Amouyel P, de Jager P, Reitz C, Mosley TH, Lambert JC, Seshadri S, van Duijn CM. Plasma amyloid β levels are driven by genetic variants near APOE, BACE1, APP, PSEN2: A genome-wide association study in over 12,000 non-demented participants. Alzheimers Dement. 2021 May 18. doi: 10.1002/alz.12333.

de Heus RAA, Tzourio C, Lee EJL, Opozda M, Vincent AD, Anstey KJ, Hofman A, Kario K, Lattanzi S, Launer LJ, Ma Y, Mahajan R, Mooijaart SP, Nagai M, Peters R, Turnbull D, Yano Y; VARIABLE BRAIN Consortium, Claassen JAHR, Tully PJ. Association Between Blood Pressure Variability With Dementia and Cognitive Impairment: A Systematic Review and Meta-Analysis. Hypertension. 2021;78(5):1478-1489. doi: 10.1161/HYPERTENSIONAHA.121.17797. Epub 2021 Sep 20

de Rojas I, Moreno-Grau S, Tesi N, Grenier-Boley B, Andrade V, Jansen IE, Pedersen NL, Stringa N, Zettergren A, Hernández I, Montrreal L, Antúnez C, Antonell A, Tankard RM, Bis JC, Sims R, Bellenguez C, Quintela I, González-Perez A, Calero M, Franco-Macías E, Macías J, Blesa R, Cervera-Carles L, Menéndez-González M, Frank-García A, Royo JL, Moreno F, Huerto Vilas R, Baquero M, Diez-Fairen M, Lage C, García-Madrona S, García-González P, Alarcón-Martín E, Valero S, Sotolongo-Grau O, Ullgren A, Naj AC, Lemstra AW, Benaque A, Pérez-Cordón A, Benussi A, Rábano A, Padovani A, Squassina A, de Mendonça A, Arias Pastor A, Kok AAL, Meggy A, Pastor AB, Espinosa A, Corma-Gómez A, Martín Montes A, Sanabria Á, DeStefano AL, Schneider A, Haapasalo A, Kinhult Ståhlbom A, Tybjærg-Hansen A, Hartmann AM, Spottke A, Corbatón-Anchuelo A, Rongve A, Borroni B, Arosio B, Nacmias B, Nordestgaard BG, Kunkle BW, Charbonnier C, Abdelnour C, Masullo C, Martínez Rodríguez C, Muñoz-Fernandez C, Dufouil C, Graff C, Ferreira CB, Chillotti C, Reynolds CA, Fenoglio C, Van Broeckhoven C, Clark C, Pisanu C, Satizabal CL, Holmes C, Buiza-Rueda D, Aarsland D, Rujescu D, Alcolea D, Galimberti D, Wallon D, Seripa D, Grünblatt E, Dardiotis E, Düzel E, Scarpini E, Conti E, Rubino E, Gelpi E, Rodriguez-Rodriguez E, Duron E, Boerwinkle E, Ferri E, Tagliavini F, Küçükali F, Pasquier F, Sanchez-Garcia F, Mangialasche F, Jessen F, Nicolas G, Selbæk G, Ortega G, Chêne G, Hadjigeorgiou G, Rossi G, Spalletta G, Giaccone G, Grande G, Binetti G, Papenberg G, Hampel H, Bailly H, Zetterberg H, Soininen H, Karlsson IK, Alvarez I, Appollonio I, Giegling I, Skoog I, Saltvedt I, Rainero I, Rosas Allende I, Hort J, Diehl-Schmid J, Van Dongen J, Vidal JS, Lehtisalo J, Wiltfang J, Thomassen JQ, Kornhuber J, Haines JL, Vogelgsang J, Pineda JA, Fortea J, Popp J, Deckert J, Buerger K, Morgan K, Fließbach K, Sleegers K, Molina-Porcel L, Kilander L, Weinhold L, Farrer LA, Wang LS, Kleineidam L, Farotti L, Parnetti L, Tremolizzo L, Hausner L, Benussi L, Froelich L, Ikram MA, Deniz-Naranjo MC, Tsolaki M, Rosende-Roca M, Löwenmark M, Hulsman M, Spallazzi M, Pericak-Vance MA, Esiri M, Bernal Sánchez-Arjona M, Dalmasso MC, Martínez-Larrad MT, Arcaro M, Nöthen MM, Fernández-Fuertes M, Dichgans M, Ingelsson M, Herrmann MJ, Scherer M, Vyhnalek M, Kosmidis MH, Yannakoulia M, Schmid M, Ewers M, Heneka MT, Wagner M, Scamosci M, Kivipelto M, Hiltunen M, Zulaica M, Alegret M, Fornage M, Roberto N, van Schoor NM, Seidu NM, Banaj N, Armstrong NJ, Scarmeas N, Scherbaum N, Goldhardt O, Hanon O, Peters O, Skrobot OA, Quenez O, Lerch O, Bossù P, Caffarra P, Dionigi Rossi P, Sakka P, Hoffmann P, Holmans PA, Fischer P, Riederer P, Yang Q, Marshall R, Kalaria RN, Mayeux R, Vandenberghe R, Cecchetti R, Ghidoni R, Frikke-Schmidt R, Sorbi S, Hägg S, Engelborghs S, Helisalmi S, Botne Sando S, Kern S, Archetti S, Boschi S, Fostinelli S, Gil S, Mendoza S, Mead S, Ciccone S, Djurovic S, Heilmann-Heimbach S, Riedel-Heller S, Kuulasmaa T, Del Ser T, Lebouvier T, Polak T, Ngandu T, Grimmer T, Bessi V, Escott-Price V, Giedraitis V, Deramecourt V, Maier W, Jian X, Pijnenburg YAL; EADB contributors; GR@ACE study group; DEGESCO consortium; IGAP (ADGC, CHARGE, EADI, GERAD); PGC-ALZ consortia, Kehoe PG, Garcia-Ribas G, Sánchez-Juan P, Pastor P, Pérez-Tur J, Piñol-Ripoll G, Lopez de Munain A, García-Alberca JM, Bullido MJ, Álvarez V, Lleó A, Real LM, Mir P, Medina M, Scheltens P, Holstege H, Marquié M, Sáez ME, Carracedo Á, Amouyel P, Schellenberg GD, Williams J, Seshadri S, van Duijn CM, Mather KA, Sánchez-Valle R, Serrano-Ríos M, Orellana A, Tárraga L, Blennow K, Huisman M, Andreassen OA, Posthuma D, Clarimón J, Boada M, van der Flier WM, Ramirez A, Lambert JC, van der Lee SJ, Ruiz A. Common variants in Alzheimer’s disease and risk stratification by polygenic risk scores. Nat Commun. 2021;12(1):3417. doi: 10.1038/s41467-021-22491-8

Du Preez A, Lefèvre-Arbogast S, Houghton V, de Lucia C, Low DY, Helmer C, Féart C, Delcourt C, Proust-Lima C, Pallàs M, Ruigrok SR, Altendorfer B, González-Domínguez R, Sánchez-Pla A, Urpi-Sardà M, Andres-Lacueva C, Aigner L, Lucassen PJ, Korosi A, Manach C, Samieri C, Thuret S. The serum metabolome mediates the concert of diet, exercise, and neurogenesis, determining the risk for cognitive decline and dementia. Alzheimers Dement. 2021 Aug 17. doi: 10.1002/alz.12428. Online ahead of print.

Dupré C, Helmer C, Bongue B, Dartigues JF, Roche F, Berr C, Carrière I. Associations between physical activity types and multi-domain cognitive decline in older adults from the Three-city cohort. PLoS One. 2021;16(6):e0252500. eCollection 2021

Georges A, Yang ML, Berrandou TE, Bakker MK, Dikilitas O, Kiando SR, Ma L, Satterfield BA, Sengupta S, Yu M, Deleuze JF, Dupré D, Hunker KL, Kyryachenko S, Liu L, Sayoud-Sadeg I, Amar L, Brummett CM, Coleman DM, d’Escamard V, de Leeuw P, Fendrikova-Mahlay N, Kadian-Dodov D, Li JZ, Lorthioir A, Pappaccogli M, Prejbisz A, Smigielski W, Stanley JC, Zawistowski M, Zhou X, Zöllner S; FEIRI investigators; International Stroke Genetics Consortium (ISGC) Intracranial Aneurysm Working Group; MEGASTROKE, Amouyel P, De Buyzere ML, Debette S, Dobrowolski P, Drygas W, Gornik HL, Olin JW, Piwonski J, Rietzschel ER, Ruigrok YM, Vikkula M, Warchol Celinska E, Januszewicz A, Kullo IJ, Azizi M, Jeunemaitre X, Persu A, Kovacic JC, Ganesh SK, Bouatia-Naji N. Genetic investigation of fibromuscular dysplasia identifies risk loci and shared genetics with common cardiovascular diseases. Nat Commun. 2021;12(1):6031

Gomez-Cabrero D, Walter S, Abugessaisa I, Miñambres-Herraiz R, Palomares LB, Butcher L, Erusalimsky JD, Garcia-Garcia FJ, Carnicero J, Hardman TC, Mischak H, Zürbig P, Hackl M, Grillari J, Fiorillo E, Cucca F, Cesari M, Carrie I, Colpo M, Bandinelli S, Feart C, Peres K, Dartigues JF, Helmer C, Viña J, Olaso G, García-Palmero I, Martínez JG, Jansen-Dürr P, Grune T, Weber D, Lippi G, Bonaguri C, Sinclair AJ, Tegner J, Rodriguez-Mañas L; FRAILOMIC initiative. A robust machine learning framework to identify signatures for frailty: a nested case-control study in four aging European cohorts. Geroscience. 2021;43(3):1317-1329. Epub 2021 Feb 18

González-Domínguez R, Castellano-Escuder P, Carmona F, Lefèvre-Arbogast S, Low DY, Du Preez A, Ruigrok SR, Manach C, Urpi-Sarda M, Korosi A, Lucassen PJ, Aigner L, Pallàs M, Thuret S, Samieri C, Sánchez-Pla A, Andres-Lacueva C. Food and Microbiota Metabolites Associate with Cognitive Decline in Older Subjects: A 12-Year Prospective Study. Mol Nutr Food Res. 2021;65(23):e2100606. doi: 10.1002/mnfr.202100606. Epub 2021 Oct 28

Harris WS, Tintle NL, Imamura F, Qian F, Korat AVA, Marklund M, Djoussé L, Bassett JK, Carmichael PH, Chen YY, Hirakawa Y, Küpers LK, Laguzzi F, Lankinen M, Murphy RA, Samieri C, Senn MK, Shi P, Virtanen JK, Brouwer IA, Chien KL, Eiriksdottir G, Forouhi NG, Geleijnse JM, Giles GG, Gudnason V, Helmer C, Hodge A, Jackson R, Khaw KT, Laakso M, Lai H, Laurin D, Leander K, Lindsay J, Micha R, Mursu J, Ninomiya T, Post W, Psaty BM, Risérus U, Robinson JG, Shadyab AH, Snetselaar L, Sala-Vila A, Sun Y, Steffen LM, Tsai MY, Wareham NJ, Wood AC, Wu JHY, Hu F, Sun Q, Siscovick DS, Lemaitre RN, Mozaffarian D; Fatty Acids and Outcomes Research Consortium (FORCE). Blood n-3 fatty acid levels and total and cause-specific mortality from 17 prospective studies. Nat Commun. 2021;12(1):2329.

Hernández-Ruiz V, Meillon C, Avila-Funes JA, Bergua V, Dartigues JF, Koleck M, Letenneur L, Ouvrard C, Pérès K, Rascle N, Tabue-Teguo M, Amieva H. Older Adults and the COVID-19 Pandemic, What About the Oldest Old? The PACOVID Population-Based Survey. Front Psychiatry. 2021;12:711583. eCollection 2021

Lefèvre-Arbogast S, Hejblum BP, Helmer C, Klose C, Manach C, Low DY, Urpi-Sarda M, Andres-Lacueva C, González-Domínguez R, Aigner L, Altendorfer B, Lucassen PJ, Ruigrok SR, De Lucia C, Du Preez A, Proust-Lima C, Thuret S, Korosi A, Samieri C. Early signature in the blood lipidome associated with subsequent cognitive decline in the elderly: A case-control analysis nested within the Three-City cohort study. EBioMedicine. 2021 Feb;64:103216. Epub 2021 Jan 25

Le Grand Q, Satizabal CL, Sargurupremraj M, Mishra A, Soumaré A, Laurent A, Crivello F, Tsuchida A, Shin J, Macalli M, Singh B, Beiser AS, DeCarli C, Fletcher E, Paus T, Lathrop M, Adams HHH, Bis JC, Seshadri S, Tzourio C, Mazoyer B, Debette S. Genomic studies across the lifespan point to early mechanisms determining subcortical volumes. Biol Psychiatry Cogn Neurosci Neuroimaging. 2021 Oct 23:S2451-9022(21)00286-X. doi: 10.1016/j.bpsc.2021.10.011

Letellier N, Ilango SD, Mortamais M, Tzourio C, Gabelle A, Empana JP, Samieri C, Berr C, Benmarhnia T. Socioeconomic inequalities in dementia risk among a French population-based cohort: quantifying the role of cardiovascular health and vascular events. Eur J Epidemiol. 2021;36(10):1015-1023. Epub 2021 Jul 25

Linard M, Baillet M, Letenneur L, Garrigue I, Catheline G, Dartigues JF, Peres K, Helmer C. Herpes simplex virus, early neuroimaging markers and incidence of Alzheimer’s disease. Transl Psychiatry. 2021;11(1):414. doi: 10.1038/s41398-021-01532-2

Madrid L, Moreno-Grau S, Ahmad S, González-Pérez A, de Rojas I, Xia R, Martino Adami PV, García-González P, Kleineidam L, Yang Q, Damotte V, Bis JC, Noguera-Perea F, Bellenguez C, Jian X, Marín-Muñoz J, Grenier-Boley B, Orellana A, Ikram MA, Amouyel P, Satizabal CL; Alzheimer’s Disease Neuroimaging Initiative (ADNI)*; EADI consortium, CHARGE consortium, GERAD consortium, GR@ACE/DEGESCO consortium, Real LM, Antúnez-Almagro C, DeStefano A, Cabrera-Socorro A, Sims R, Van Duijn CM, Boerwinkle E, Ramírez A, Fornage M, Lambert JC, Williams J, Seshadri S; ADAPTED consortium, Ried JS, Ruiz A, Saez ME. Multiomics integrative analysis identifies APOE allele-specific blood biomarkers associated to Alzheimer’s disease etiopathogenesis. Aging (Albany NY). 2021;13(7):9277-9329. Online ahead of print

Mauschitz MM, Schmitz MT, Verzijden T, Schmid M, Thee EF, Colijn JM, Delcourt C, Cougnard-Grégoire A, Merle BMJ, Korobelnik JF, Gopinath B, Mitchell P, Elbaz H, Schuster AK, Wild PS, Brandl C, Stark KJ, Heid IM, Günther F, Peters A, Klaver CCW, Finger RP; European Eye Epidemiology (E3) Consortium. Physical Activity, Incidence, and Progression of Age-Related Macular Degeneration: A Multicohort Study. Am J Ophthalmol. 2021 Oct 22;236:99-106. doi: 10.1016/j.ajo.2021.10.008.

Merle BMJ, Cougnard-Grégoire A, Korobelnik JF, Schalch W, Etheve S, Rougier MB, Féart C, Samieri C, Delyfer MN, Delcourt C. Plasma Lutein, a Nutritional Biomarker for Development of Advanced Age-Related Macular Degeneration: The Alienor Study. Nutrients. 2021 Jun 15;13(6):2047. doi: 10.3390/nu13062047

Morillon C, Le Goff M, Gattoussi S, Korobelnik JF, Rougier MB, Schweitzer C, Delcourt C, Delyfer MN. Incidence, progression and risk factors of epiretinal membranes in the elderly. Retina. 2021 Mar 1;41(3):495-504.

Mortamais M, Gutierrez LA, de Hoogh K, Chen J, Vienneau D, Carrière I, Letellier N, Helmer C, Gabelle A, Mura T, Sunyer J, Benmarhnia T, Jacquemin B, Berr C. Long-term exposure to ambient air pollution and risk of dementia: Results of the prospective Three-City Study. Environ Int. 2021;148:106376. Epub 2021 Jan 2

NCD Risk Factor Collaboration (NCD-RisC). Worldwide trends in hypertension prevalence and progress in treatment and control from 1990 to 2019: a pooled analysis of 1201 population-representative studies with 104 million participants. Lancet. 2021;398(10304):957-980. Epub 2021 Aug 24

NCD Risk Factor Collaboration (NCD-RisC). Heterogeneous contributions of change in population distribution of body mass index to change in obesity and underweight. Elife. 2021;10:e60060. doi: 10.7554/eLife.60060

Pérès K, Ouvrard C, Koleck M, Rascle N, Dartigues JF, Bergua V, Amieva H. Living in rural area: A protective factor for a negative experience of the lockdown and the COVID-19 crisis in the oldest old population? Int J Geriatr Psychiatry. 2021;36(12):1950-1958. Epub 2021 Aug 26.

Peters R, Xu Y, Antikainen R, Beckett N, Gussekloo J, Jagger C, Jukema JW, Keinanen-Kiukaanniemi S, Rydén L, Skoog I, Staessen JA, Thijs L, Trompet S, Tully PJ, Tzourio C, Anstey KJ. Evaluation of High Cholesterol and Risk of Dementia and Cognitive Decline in Older Adults Using Individual Patient Meta-Analysis. Dement Geriatr Cogn Disord. 2021;50(4):318-325. Epub 2021 Oct 26

Pilleron S, Le Goff M, Ajana S, Helmer C, Pérès K, Dartigues JF, Tabue-Teguo M, Féart C. Self-Rated Health and Frailty in Older Adults from the Population-Based Three-City Bordeaux Cohort. Gerontology. 2021 Oct 18:1-8. doi: 10.1159/000518864. Online ahead of print.

Pin G, Coupé P, Nadal L, Manjon JV, Helmer C, Amieva H, Mazoyer B, Dartigues JF, Catheline G, Planche V. Distinct Hippocampal Subfields Atrophy in Older People With Vascular Brain Injuries. Stroke. 2021;52(5):1741-1750. Epub 2021 Mar 4

Qian F, Ardisson Korat AV, Imamura F, Marklund M, Tintle N, Virtanen JK, Zhou X, Bassett JK, Lai H, Hirakawa Y, Chien KL, Wood AC, Lankinen M, Murphy RA, Samieri C, Pertiwi K, de Mello VD, Guan W, Forouhi NG, Wareham N, Hu ICFB, Riserus U, Lind L, Harris WS, Shadyab AH, Robinson JG, Steffen LM, Hodge A, Giles GG, Ninomiya T, Uusitupa M, Tuomilehto J, Lindström J, Laakso M, Siscovick DS, Helmer C, Geleijnse JM, Wu JHY, Fretts A, Lemaitre RN, Micha R, Mozaffarian D, Sun Q; Fatty Acids and Outcomes Research Consortium (FORCE). n-3 Fatty Acid Biomarkers and Incident Type 2 Diabetes: An Individual Participant-Level Pooling Project of 20 Prospective Cohort Studies. Diabetes Care. 2021;44(5):1133-1142. Epub 2021 Mar 3

Rahi B, Pellay H, Chuy V, Helmer C, Samieri C, Féart C. Dairy Product Intake and Long-Term Risk for Frailty among French Elderly Community Dwellers. Nutrients. 2021;13(7):2151.

Rouanet A, Avila-Rieger J, Dugravot A, Lespinasse J, Stuckwisch R, Merrick R, Anderson E, Long L, Helmer C, Jacqmin-Gadda H, Dufouil C, Judd S, Manly J, Sabia S, Gross A, Proust-Lima C. How Selection Over Time Contributes to the Inconsistency of the Association between Sex/Gender and Cognitive Decline across Cognitive Aging Cohorts. Am J Epidemiol. 2021 Sep 14:kwab227. Online ahead of print.

Thomas A, Crivello F, Mazoyer B, Debette S, Tzourio C, Samieri C. Fish Intake and MRI Burden of Cerebrovascular Disease in Older Adults. Neurology. 2021;97(22):e2213-e2222. Epub 2021 Nov 3

Thomas A, Proust-Lima C, Baillet M, Helmer C, Delcourt C, Foubert-Samier A, Catheline G, Féart C, Samieri C. Plasma carotenoids and medial temporal lobe atrophy in older adults. Clin Nutr. 2021;40(4):2460-2463. Epub 2020 Oct 14.

van Rheenen W, van der Spek RAA, Bakker MK, van Vugt JJFA, Hop PJ, Zwamborn RAJ, de Klein N, Westra HJ, Bakker OB, Deelen P, Shireby G, Hannon E, Moisse M, Baird D, Restuadi R, Dolzhenko E, Dekker AM, Gawor K, Westeneng HJ, Tazelaar GHP, van Eijk KR, Kooyman M, Byrne RP, Doherty M, Heverin M, Al Khleifat A, Iacoangeli A, Shatunov A, Ticozzi N, Cooper-Knock J, Smith BN, Gromicho M, Chandran S, Pal S, Morrison KE, Shaw PJ, Hardy J, Orrell RW, Sendtner M, Meyer T, Başak N, van der Kooi AJ, Ratti A, Fogh I, Gellera C, Lauria G, Corti S, Cereda C, Sproviero D, D’Alfonso S, Sorarù G, Siciliano G, Filosto M, Padovani A, Chiò A, Calvo A, Moglia C, Brunetti M, Canosa A, Grassano M, Beghi E, Pupillo E, Logroscino G, Nefussy B, Osmanovic A, Nordin A, Lerner Y, Zabari M, Gotkine M, Baloh RH, Bell S, Vourc’h P, Corcia P, Couratier P, Millecamps S, Meininger V, Salachas F, Mora Pardina JS, Assialioui A, Rojas-García R, Dion PA, Ross JP, Ludolph AC, Weishaupt JH, Brenner D, Freischmidt A, Bensimon G, Brice A, Durr A, Payan CAM, Saker-Delye S, Wood NW, Topp S, Rademakers R, Tittmann L, Lieb W, Franke A, Ripke S, Braun A, Kraft J, Whiteman DC, Olsen CM, Uitterlinden AG, Hofman A, Rietschel M, Cichon S, Nöthen MM, Amouyel P; SLALOM Consortium; PARALS Consortium; SLAGEN Consortium; SLAP Consortium, Traynor BJ, Singleton AB, Mitne Neto M, Cauchi RJ, Ophoff RA, Wiedau-Pazos M, Lomen-Hoerth C, van Deerlin VM, Grosskreutz J, Roediger A, Gaur N, Jörk A, Barthel T, Theele E, Ilse B, Stubendorff B, Witte OW, Steinbach R, Hübner CA, Graff C, Brylev L, Fominykh V, Demeshonok V, Ataulina A, Rogelj B, Koritnik B, Zidar J, Ravnik-Glavač M, Glavač D, Stević Z, Drory V, Povedano M, Blair IP, Kiernan MC, Benyamin B, Henderson RD, Furlong S, Mathers S, McCombe PA, Needham M, Ngo ST, Nicholson GA, Pamphlett R, Rowe DB, Steyn FJ, Williams KL, Mather KA, Sachdev PS, Henders AK, Wallace L, de Carvalho M, Pinto S, Petri S, Weber M, Rouleau GA, Silani V, Curtis CJ, Breen G, Glass JD, Brown RH Jr, Landers JE, Shaw CE, Andersen PM, Groen EJN, van Es MA, Pasterkamp RJ, Fan D, Garton FC, McRae AF, Davey Smith G, Gaunt TR, Eberle MA, Mill J, McLaughlin RL, Hardiman O, Kenna KP, Wray NR, Tsai E, Runz H, Franke L, Al-Chalabi A, Van Damme P, van den Berg LH, Veldink JH. Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology. Nat Genet. 2021 Dec;53(12):1636-1648. Epub 2021 Dec 6.

Yu M, Kyryachenko S, Debette S, Amouyel P, Schott JJ, Le Tourneau T, Dina C, Norris RA, Hagège AA, Jeunemaitre X, Bouatia-Naji N. Genome-Wide Association Meta-Analysis Supports Genes Involved in Valve and Cardiac Development to Associate With Mitral Valve Prolapse. Circ Genom Precis Med. 2021;14(5):e003148. Epub 2021 Aug 31

Bordes C, Sargurupremraj M, Mishra A, Debette S. Genetics of common cerebral small vessel disease. Nat Rev Neurol. 2022 Jan 5. doi: 10.1038/s41582-021-00592-8. Online ahead of print

Cavaillès C, Berr C, Helmer C, Gabelle A, Jaussent I, Dauvilliers Y. Complaints of daytime sleepiness, insomnia, hypnotic use, and risk of dementia: a prospective cohort study in the elderly. Alzheimers Res Ther. 2022;14(1):12

Chuy V, Gentreau M, Artero S, Berticat C, Rigalleau V, Pérès K, Helmer C, Samieri C, Féart C. Simple Carbohydrate Intake and Higher Risk for Physical Frailty Over 15 Years in Community-Dwelling Older Adults. J Gerontol A Biol Sci Med Sci. 2022;77(1):10-18.

Dartigues JF, Le Bourdonnec K, Tabue-Teguo M, Le Goff M, Helmer C, Avila-Funes JA, Coureau G, Feart C, Pérès K, Genuer R, Letenneur L, Amieva H, Proust-Lima C. Co-Occurrence of Geriatric Syndromes and Diseases in the General Population: Assessment of the Dimensions of Aging. J Nutr Health Aging. 2022;26(1):37-45.

Duchesne J, Gutierrez LA, Carrière I, Mura T, Chen J, Vienneau D, de Hoogh K, Helmer C, Jacquemin B, Berr C, Mortamais M. Exposure to ambient air pollution and cognitive decline: Results of the prospective Three-City cohort study. Environ Int. 2022 Feb 3;161:107118. doi: 10.1016/j.envint.2022.107118. Online ahead of print

González-Domínguez R, Castellano-Escuder P, Lefèvre-Arbogast S, Low DY, Du Preez A, Ruigrok SR, Lee H, Helmer C, Pallàs M, Urpi-Sarda M, Sánchez-Pla A, Korosi A, Lucassen PJ, Aigner L, Manach C, Thuret S, Samieri C, Andres-Lacueva C. Apolipoprotein E and sex modulate fatty acid metabolism in a prospective observational study of cognitive decline. Alzheimers Res Ther. 2022 Jan 3;14(1):1. doi: 10.1186/s13195-021-00948-8

Letellier N, Gutierrez LA, Duchesne J, Chen C, Ilango S, Helmer C, Berr C, Mortamais M, Benmarhnia T. Air quality improvement and incident dementia: Effects of observed and hypothetical reductions in air pollutant using parametric g-computation. Alzheimers Dement. 2022 Feb 9. doi: 10.1002/alz.12606. Online ahead of print.

Neuffer J, Gourru M, Thomas A, Lefèvre-Arbogast S, Foubert-Samier A, Helmer C, Delcourt C, Féart C, Samieri C. A Biological Index to Screen Multi-Micronutrient Deficiencies Associated with the Risk to Develop Dementia in Older Persons from the Community. J Alzheimers Dis. 2022;85(1):331-342.

Pavlik VN, Burnham SC, Kass JS, Helmer C, Palmqvist S, Vassilaki M, Dartigues JF, Hansson O, Masters CL, Pérès K, Petersen RC, Stomrud E, Butler L, Coloma PM, Teitsma XM, Doody R, Sano M; CONCORD-AD investigators. Connecting Cohorts to Diminish Alzheimer’s Disease (CONCORD-AD): A Report of an International Research Collaboration Network. J Alzheimers Dis. 2022;85(1):31-45.